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The map label for this gene is ftsW [H]

Identifier: 37523150

GI number: 37523150

Start: 3772455

End: 3773750

Strand: Reverse

Name: ftsW [H]

Synonym: gvip487

Alternate gene names: 37523150

Gene position: 3773750-3772455 (Counterclockwise)

Preceding gene: 37523151

Following gene: 37523149

Centisome position: 81.0

GC content: 65.59

Gene sequence:

>1296_bases
ATGCCTACGCTTCTCGAAAGATTGCAGGCTCCTTTGCGGGAGCGCACCGGCGAAACCAGCCCGAACGCATGGGTGCCGGA
GGCGCGCCTGCTGGTCGTGCTCATCCTCTGCTGGCTCGCCCTCGGCCTGCTGGTGCTCTTTTCGGCTTCTTTGCCGGTGG
GTGAGCTGCAGTACGACGACGGGTTGCGATTTTTTACGCGCCAGGCGCTCACGGCGGCGGTGGGGTTGCTGCTGATGTTC
TGGCTGTGCCGAACGCGCATCGACCGCCTGTTTGCCGTGGCTTTGCCGGTGTTCGGGGTGCTGCTGGCGATGGTGTTTTT
GGTCAAAATTCCGGGTATCGGCGTCGAGCTGAACGGCGCGCGCCGCTGGCTCCAGCTGGGGCCTTTCTCGCTGCAGCCTT
CTGAACTGATCAAGCCCTGCGTCATTTTGCTGGCGGCCCCGCTGATCGCCAACTGGCGAAGGCTGCCGAATTTTACGCGC
CTGCTCGGTCTGGTGGCTGCGGGCCTGACGGTGGGCGGCGTGCTGCTCCAGCCTGACCTGGGTACTGCTGCGCTGATTGG
TGTCACCCTCTGGCTGATGGGCTTTGCGGGGGGTCTGCCCCTGGGCGGCTTATTTGCGGTGCTGGCGGCCGGGGGCGCGG
TCGCTGCCTGGAAGGTAAGCACCACCGCCTATCAGATGGGCCGGGTGACCGCTTTTCTCGATCCGTGGGAGGTAGCCCGG
GGCGAAGGTTACCAGTTGGTGCAGAGTCTGCTTGCCGTCGGCTCCGGCGGCCTGCAAGGCACCGGGTTCGGCCTGTCGGC
CCAAAAATCGGCGTTCTTGCCCTACCCCTATTCCGATTTCATCTTCGCGGTCTTTTGCGAGGAGTTCGGCCTGGTCGGTG
CCGCCGCCTTTGTGCTCTTTTTGTTGCTCTTTTTGGTCGTGGGCTTGCGGGTGGCGGTGCGCTGCGCCGAACCTACGCGC
CGATTAATAGCCGCCGGTGCGACGCTGCTGTTGGTTACCCAGGCATTCTTCCACATCGCTGTGGTCACCGGTGCCGTACC
GCCCAAGGGCATGCCGCTGCCGCTGATGAGCTACGGTGGCAGCGGTTTGATTGCGAGCTTATTGTGCTGCGCTCTGCTTA
TCCGTGCCGCCTGCGAGATGAACCTTGCCCCGGCGGTGCGCTTCGTGCGCCGCCGCCCCGCCGCGCCACCGCCCCGCCCA
GTGGCGCCCGCCGCTCGTCCCGCCTCCGAACCTGTCCGGCGGGAGCCGTCGCCTTTGCCGGCGTACCTGCTCGATACGGC
TGTCCGTAGCCGGTAG

Upstream 100 bases:

>100_bases
AGATACTCAAAACCTGGTGTCTGCGAGGGAAATTGACCCCATATATGCCAACTTCGTCCCGTCTTTCAGGTAAACTGACG
GCAAAATTCTTCTTGCCGCC

Downstream 100 bases:

>100_bases
CCCGTTGAAAGTCTATTTGGCTGAGGCTGTAGGTAGACCTACTTCGTAGTAGCGGCCAGCCTCCTGCTGGTTCTCGATAA
GAATCTCCTGGGCAAGCAGG

Product: cell division protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 431; Mature: 430

Protein sequence:

>431_residues
MPTLLERLQAPLRERTGETSPNAWVPEARLLVVLILCWLALGLLVLFSASLPVGELQYDDGLRFFTRQALTAAVGLLLMF
WLCRTRIDRLFAVALPVFGVLLAMVFLVKIPGIGVELNGARRWLQLGPFSLQPSELIKPCVILLAAPLIANWRRLPNFTR
LLGLVAAGLTVGGVLLQPDLGTAALIGVTLWLMGFAGGLPLGGLFAVLAAGGAVAAWKVSTTAYQMGRVTAFLDPWEVAR
GEGYQLVQSLLAVGSGGLQGTGFGLSAQKSAFLPYPYSDFIFAVFCEEFGLVGAAAFVLFLLLFLVVGLRVAVRCAEPTR
RLIAAGATLLLVTQAFFHIAVVTGAVPPKGMPLPLMSYGGSGLIASLLCCALLIRAACEMNLAPAVRFVRRRPAAPPPRP
VAPAARPASEPVRREPSPLPAYLLDTAVRSR

Sequences:

>Translated_431_residues
MPTLLERLQAPLRERTGETSPNAWVPEARLLVVLILCWLALGLLVLFSASLPVGELQYDDGLRFFTRQALTAAVGLLLMF
WLCRTRIDRLFAVALPVFGVLLAMVFLVKIPGIGVELNGARRWLQLGPFSLQPSELIKPCVILLAAPLIANWRRLPNFTR
LLGLVAAGLTVGGVLLQPDLGTAALIGVTLWLMGFAGGLPLGGLFAVLAAGGAVAAWKVSTTAYQMGRVTAFLDPWEVAR
GEGYQLVQSLLAVGSGGLQGTGFGLSAQKSAFLPYPYSDFIFAVFCEEFGLVGAAAFVLFLLLFLVVGLRVAVRCAEPTR
RLIAAGATLLLVTQAFFHIAVVTGAVPPKGMPLPLMSYGGSGLIASLLCCALLIRAACEMNLAPAVRFVRRRPAAPPPRP
VAPAARPASEPVRREPSPLPAYLLDTAVRSR
>Mature_430_residues
PTLLERLQAPLRERTGETSPNAWVPEARLLVVLILCWLALGLLVLFSASLPVGELQYDDGLRFFTRQALTAAVGLLLMFW
LCRTRIDRLFAVALPVFGVLLAMVFLVKIPGIGVELNGARRWLQLGPFSLQPSELIKPCVILLAAPLIANWRRLPNFTRL
LGLVAAGLTVGGVLLQPDLGTAALIGVTLWLMGFAGGLPLGGLFAVLAAGGAVAAWKVSTTAYQMGRVTAFLDPWEVARG
EGYQLVQSLLAVGSGGLQGTGFGLSAQKSAFLPYPYSDFIFAVFCEEFGLVGAAAFVLFLLLFLVVGLRVAVRCAEPTRR
LIAAGATLLLVTQAFFHIAVVTGAVPPKGMPLPLMSYGGSGLIASLLCCALLIRAACEMNLAPAVRFVRRRPAAPPPRPV
APAARPASEPVRREPSPLPAYLLDTAVRSR

Specific function: This is a septum-peptidoglycan biosynthetic protein, involved in cell wall formation. Plays a role in the stabilization of the ftsZ ring during cell division [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=386, Percent_Identity=31.8652849740933, Blast_Score=162, Evalue=5e-41,
Organism=Escherichia coli, GI1786853, Length=268, Percent_Identity=38.0597014925373, Blast_Score=132, Evalue=4e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 45956; Mature: 45824

Theoretical pI: Translated: 10.22; Mature: 10.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTLLERLQAPLRERTGETSPNAWVPEARLLVVLILCWLALGLLVLFSASLPVGELQYDD
CCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
GLRFFTRQALTAAVGLLLMFWLCRTRIDRLFAVALPVFGVLLAMVFLVKIPGIGVELNGA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCH
RRWLQLGPFSLQPSELIKPCVILLAAPLIANWRRLPNFTRLLGLVAAGLTVGGVLLQPDL
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCEEECCCC
GTAALIGVTLWLMGFAGGLPLGGLFAVLAAGGAVAAWKVSTTAYQMGRVTAFLDPWEVAR
CHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHEECCHHHHHC
GEGYQLVQSLLAVGSGGLQGTGFGLSAQKSAFLPYPYSDFIFAVFCEEFGLVGAAAFVLF
CCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHH
LLLFLVVGLRVAVRCAEPTRRLIAAGATLLLVTQAFFHIAVVTGAVPPKGMPLPLMSYGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCC
SGLIASLLCCALLIRAACEMNLAPAVRFVRRRPAAPPPRPVAPAARPASEPVRREPSPLP
CHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCH
AYLLDTAVRSR
HHHHHHHHHCC
>Mature Secondary Structure 
PTLLERLQAPLRERTGETSPNAWVPEARLLVVLILCWLALGLLVLFSASLPVGELQYDD
CHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
GLRFFTRQALTAAVGLLLMFWLCRTRIDRLFAVALPVFGVLLAMVFLVKIPGIGVELNGA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCH
RRWLQLGPFSLQPSELIKPCVILLAAPLIANWRRLPNFTRLLGLVAAGLTVGGVLLQPDL
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCEEECCCC
GTAALIGVTLWLMGFAGGLPLGGLFAVLAAGGAVAAWKVSTTAYQMGRVTAFLDPWEVAR
CHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHEECCHHHHHC
GEGYQLVQSLLAVGSGGLQGTGFGLSAQKSAFLPYPYSDFIFAVFCEEFGLVGAAAFVLF
CCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHH
LLLFLVVGLRVAVRCAEPTRRLIAAGATLLLVTQAFFHIAVVTGAVPPKGMPLPLMSYGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCC
SGLIASLLCCALLIRAACEMNLAPAVRFVRRRPAAPPPRPVAPAARPASEPVRREPSPLP
CHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCH
AYLLDTAVRSR
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]