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The map label for this gene is ndh [H]

Identifier: 37523072

GI number: 37523072

Start: 3709687

End: 3710907

Strand: Direct

Name: ndh [H]

Synonym: glr3503

Alternate gene names: 37523072

Gene position: 3709687-3710907 (Clockwise)

Preceding gene: 37523071

Following gene: 37523073

Centisome position: 79.62

GC content: 66.91

Gene sequence:

>1221_bases
ATGCTGGAAGGGTCTTTCACAGCATCAGCCATGGCGCGCATTGTCATTGTCGGCGGCGGATTTGCGGGGTTGTTCACCGC
CCTTGGCCTCGAAGCGTATCCCTTCAAAGACGAGCGCCCAGAAATTCTGCTCATCGATCGCTCGGAGCGGTTTGTCTTCT
CGCCGCTCCTTTACGAACTGGTTTCGGGGGAGCTTGCCACCTGGGAGGTGGCCCCGCGCTTCGACGAATTGCTCGAAGGG
ACGCGGGTGCGCTTCGTGCAGGCCGAGGCGATGGGTTTCGACTTCGAAAACCGCATCGTCAAGCTTGCGGGCGGCGGTGC
CGAAAGTTACGACCGGCTGGCCCTTACCGTGGGCGGCAGCACACCCGTGGACATCGTGCCGGGGGCGCGCGAGCACGCCT
TGCCCTTTCGTACCCTCGAAGACGCCCAGGCGCTGATCGCCCGGCTCAAGGCCGCCCTCGATGCCGGGGCCGACCCTGTG
CGCGCAGCCCTGGTGGGGGCGGGGGCAAGCGGCGTCGAACTCGCCTGCAAACTCGCCGACACCCTAGGCGACAAAGGCAG
CATCGTTTTGTTCGACCGCGCAGCGGACATCCTGGCCGAGTTCGACGCGCCGGAGCGCAAAATGGCCCGTGCCGAACTCG
AAAAGCGCAGAGTGCGGCTGGGACTCTCCACAAAAATTCTGTCGGTGAGCGATGCGGGCCTGCAAGTCGAGACCGCCGGG
CGCGGCGTCGAGGCGATCCCCGCCGAGGTGGTGCTCTGGACGGTGGGGACGGCGGTGCCGGGGCTCATCAAAGATCTCGA
TCTGCCCAAGGGGCCGGGCGGACGGCTGGCCGTCGAGCCCACCTTGCAGGTGCAGGGGCACCCCGAAATCTTCGCCTTAG
GCGATCTGGCAGCGAGCCTCGATGCCGGCGGCAAGCCGCTCGGTCCCAGTGCCCAGTTGGCCTTCCAACAGGCGGGCTAC
TGCGCGTGGAATCTCTGGGCGAGCCTGAGCGACCGGCCGCTGCTCGCCTTTCGCTACAACGCGCTGGGCAAGCTGTTGGG
GTTGGGGATCGACAGCGGCGTCGCCTCGCTTCTGGGCACGGCCGTCGGCGGTCCGCCCGCCTATCTCATCCGCCGACTGG
CGTATCTTTACCGGATGCCCACCGACGCCCACCGGCTGAAAGTGGCCCTGCACTGGGCAAGTCGGCCTGTTGTGCGCTGG
CTGGGCGGGGCGGCACCTTAG

Upstream 100 bases:

>100_bases
TGCTGCAGCAGACCGATCTGCGCGGCCTGGACCTGGCCAGACTGGATCTCGAAGACACCGACGCCTCGGCAGCCCGCGTC
CGCTAACGATTGGCGCGGCT

Downstream 100 bases:

>100_bases
AGTAGGATTGTACCCACATCGGGTGAGATGCCCTTTCAGCCTATCTGCAGAAAATGAGTCTGTGAATGCACCGTTCGCAG
TTCAGGTTTCCGCAGGCCCT

Product: NADH dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 406; Mature: 406

Protein sequence:

>406_residues
MLEGSFTASAMARIVIVGGGFAGLFTALGLEAYPFKDERPEILLIDRSERFVFSPLLYELVSGELATWEVAPRFDELLEG
TRVRFVQAEAMGFDFENRIVKLAGGGAESYDRLALTVGGSTPVDIVPGAREHALPFRTLEDAQALIARLKAALDAGADPV
RAALVGAGASGVELACKLADTLGDKGSIVLFDRAADILAEFDAPERKMARAELEKRRVRLGLSTKILSVSDAGLQVETAG
RGVEAIPAEVVLWTVGTAVPGLIKDLDLPKGPGGRLAVEPTLQVQGHPEIFALGDLAASLDAGGKPLGPSAQLAFQQAGY
CAWNLWASLSDRPLLAFRYNALGKLLGLGIDSGVASLLGTAVGGPPAYLIRRLAYLYRMPTDAHRLKVALHWASRPVVRW
LGGAAP

Sequences:

>Translated_406_residues
MLEGSFTASAMARIVIVGGGFAGLFTALGLEAYPFKDERPEILLIDRSERFVFSPLLYELVSGELATWEVAPRFDELLEG
TRVRFVQAEAMGFDFENRIVKLAGGGAESYDRLALTVGGSTPVDIVPGAREHALPFRTLEDAQALIARLKAALDAGADPV
RAALVGAGASGVELACKLADTLGDKGSIVLFDRAADILAEFDAPERKMARAELEKRRVRLGLSTKILSVSDAGLQVETAG
RGVEAIPAEVVLWTVGTAVPGLIKDLDLPKGPGGRLAVEPTLQVQGHPEIFALGDLAASLDAGGKPLGPSAQLAFQQAGY
CAWNLWASLSDRPLLAFRYNALGKLLGLGIDSGVASLLGTAVGGPPAYLIRRLAYLYRMPTDAHRLKVALHWASRPVVRW
LGGAAP
>Mature_406_residues
MLEGSFTASAMARIVIVGGGFAGLFTALGLEAYPFKDERPEILLIDRSERFVFSPLLYELVSGELATWEVAPRFDELLEG
TRVRFVQAEAMGFDFENRIVKLAGGGAESYDRLALTVGGSTPVDIVPGAREHALPFRTLEDAQALIARLKAALDAGADPV
RAALVGAGASGVELACKLADTLGDKGSIVLFDRAADILAEFDAPERKMARAELEKRRVRLGLSTKILSVSDAGLQVETAG
RGVEAIPAEVVLWTVGTAVPGLIKDLDLPKGPGGRLAVEPTLQVQGHPEIFALGDLAASLDAGGKPLGPSAQLAFQQAGY
CAWNLWASLSDRPLLAFRYNALGKLLGLGIDSGVASLLGTAVGGPPAYLIRRLAYLYRMPTDAHRLKVALHWASRPVVRW
LGGAAP

Specific function: Transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Does not couple the redox reaction to proton translocation [H]

COG id: COG1252

COG function: function code C; NADH dehydrogenase, FAD-containing subunit

Gene ontology:

Cell location: Cell membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787352, Length=418, Percent_Identity=28.7081339712919, Blast_Score=121, Evalue=8e-29,
Organism=Saccharomyces cerevisiae, GI6323794, Length=450, Percent_Identity=24, Blast_Score=84, Evalue=6e-17,
Organism=Saccharomyces cerevisiae, GI6323515, Length=338, Percent_Identity=28.1065088757396, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6320118, Length=408, Percent_Identity=23.0392156862745, Blast_Score=69, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.6.99.3 [H]

Molecular weight: Translated: 43001; Mature: 43001

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEGSFTASAMARIVIVGGGFAGLFTALGLEAYPFKDERPEILLIDRSERFVFSPLLYEL
CCCCCCCHHCEEEEEEECCCHHHHHHHHCCCCCCCCCCCCCEEEEECCCCEEHHHHHHHH
VSGELATWEVAPRFDELLEGTRVRFVQAEAMGFDFENRIVKLAGGGAESYDRLALTVGGS
HCCCCEEEEECCCHHHHHCCCEEEEEEHHHHCCCHHHCEEEEECCCCCCCCEEEEEECCC
TPVDIVPGAREHALPFRTLEDAQALIARLKAALDAGADPVRAALVGAGASGVELACKLAD
CCEEECCCCHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHEECCCCCCHHHHHHHHH
TLGDKGSIVLFDRAADILAEFDAPERKMARAELEKRRVRLGLSTKILSVSDAGLQVETAG
HCCCCCCEEEEECHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEECC
RGVEAIPAEVVLWTVGTAVPGLIKDLDLPKGPGGRLAVEPTLQVQGHPEIFALGDLAASL
CCCCCCCCEEEEEEHHHHHHHHHHHCCCCCCCCCCEEECCEEEECCCCCEEEECCHHHHH
DAGGKPLGPSAQLAFQQAGYCAWNLWASLSDRPLLAFRYNALGKLLGLGIDSGVASLLGT
CCCCCCCCCCHHHHHHHCCCEEEEHHHCCCCCCEEEEEHHHHHHHHHCCCCHHHHHHHHH
AVGGPPAYLIRRLAYLYRMPTDAHRLKVALHWASRPVVRWLGGAAP
HCCCCHHHHHHHHHHHHCCCCCHHEEEEEEEECCCHHHHHHCCCCC
>Mature Secondary Structure
MLEGSFTASAMARIVIVGGGFAGLFTALGLEAYPFKDERPEILLIDRSERFVFSPLLYEL
CCCCCCCHHCEEEEEEECCCHHHHHHHHCCCCCCCCCCCCCEEEEECCCCEEHHHHHHHH
VSGELATWEVAPRFDELLEGTRVRFVQAEAMGFDFENRIVKLAGGGAESYDRLALTVGGS
HCCCCEEEEECCCHHHHHCCCEEEEEEHHHHCCCHHHCEEEEECCCCCCCCEEEEEECCC
TPVDIVPGAREHALPFRTLEDAQALIARLKAALDAGADPVRAALVGAGASGVELACKLAD
CCEEECCCCHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHEECCCCCCHHHHHHHHH
TLGDKGSIVLFDRAADILAEFDAPERKMARAELEKRRVRLGLSTKILSVSDAGLQVETAG
HCCCCCCEEEEECHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEECC
RGVEAIPAEVVLWTVGTAVPGLIKDLDLPKGPGGRLAVEPTLQVQGHPEIFALGDLAASL
CCCCCCCCEEEEEEHHHHHHHHHHHCCCCCCCCCCEEECCEEEECCCCCEEEECCHHHHH
DAGGKPLGPSAQLAFQQAGYCAWNLWASLSDRPLLAFRYNALGKLLGLGIDSGVASLLGT
CCCCCCCCCCHHHHHHHCCCEEEEHHHCCCCCCEEEEEHHHHHHHHHCCCCHHHHHHHHH
AVGGPPAYLIRRLAYLYRMPTDAHRLKVALHWASRPVVRWLGGAAP
HCCCCHHHHHHHHHHHHCCCCCHHEEEEEEEECCCHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 6265208; 8905232; 9278503 [H]