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The map label for this gene is speA [H]

Identifier: 37523056

GI number: 37523056

Start: 3697533

End: 3698936

Strand: Reverse

Name: speA [H]

Synonym: gll3487

Alternate gene names: 37523056

Gene position: 3698936-3697533 (Counterclockwise)

Preceding gene: 37523059

Following gene: 37523055

Centisome position: 79.39

GC content: 67.88

Gene sequence:

>1404_bases
GTGGAAACCACTCCGCTCTGGGATGCGCTGAGGGCCGTCGCTCTAGCCTCGGGCACGGGCTTTCACACCCCGGGCCACAA
CGGCGGGGCGGGCCTGCCGCCAGCCCTCAAACACTGGCCGGATTGGGGCCGTCTGGACCTGACCGAACTTGCAGGACTCG
ACAACCTGCACGCTCCCACCGGGGTGATCGCCCACGCGCAACGGCTCGCGGCGGCAGTTTGGGGAGCCGAGCGCAGTTGG
TTTCTGGTCAACGGTGCGACCGCCGGAATCCAGGCGATGCTGCTTGCGGCACTCGGGCAGGGGCAGAAGGTGCTCGTGCC
CAGAAACTGTCACCAAAGTATCGTGCACGCCCTGGTGCTGAGCGGCGCGGTGCCGGTGTTCGTCCAACCTGTATGGGACA
GGCGCTGGCAGTTGGCCCACGGACTGACGGCGACGACGGTGGAAGCCGCCCTGGCCGTCCACCCGGACATCCGGGCGGTG
GTGGCGGTGCACCCGACGTACTTCGGGGCGGTGGGCGAGACGCGGGCCATCGCCAGGGTCGCCCACGCAAAAGGGATTGC
GCTGTTGGTCGATGCCGCCCACGGCGCCCATCTGCGCTTCCATCCGGACTTGCCCGAGTGCGCACTCGCAGCGGGAGCGG
ACTTGGTCGTCCATTCCGCCCACAAGACACTGCCCGCCCTCACCCAGGCGGCACTCCTTCACCAGCAGGGCACCCTGGTG
GACCCGGCCAGGGTGGAGATGGCTCTGAACCTTCTGCAAACCACCAGCCCGAGCTACTTGCTGATGGCCTCGCTCGATCT
GGCCCGCGCCCACATGGTCCGCCACGGCCGCGAGCAGCTCGGGCACATCCTGGAGATGGCCCATAGACTGCGACACAAAC
TGCCCTTCGCGGTGCTCGGGGGCGACGGAACGCCTGGCTTCGATCCGACCCGCCTGGTCATCGACGTGGGTGAGAAAGGC
TGGAGCGGTCACGCCGCTGAGACCTGGCTGGAGCAAAACGCCCAGGTGCGTGCGGAGATGGCCACCCACCGCCACCTGGT
CTTCATCCTCAATAGCGCCCACACCGAATTCGACGGCGAGCAACTGCAAGCATCCCTTCTGGCCCTGGCAACGGCCCAAC
CGACCGGGGCAACGCCGCCGGATCTGCTTCCACCGCCGCTTCCGGAGCTGCGCTATTCACCCCGCGAAGCTTTCGGCCGC
TCCCACCGGAGCGTTCCCCTAGCCGCGGCAGCCGGACTGACCAGTGCGGCCGATGTCTGCACCTACCCGCCCGGAGTGCC
GGTGCTGCTGCCGGGGGAAGTGGTTGCCGCCCAGAGCGTCGAGTATTTGGGCGCCGCCATTGACACTGGGGCCGAGACAG
TCGGGATCGACGGGCGCGGACACATCCGGGTCACTATTGACTAA

Upstream 100 bases:

>100_bases
TCATGCCATCAAAAAAGTGGGCCTCGAACCCACTCCTCCAGTCCCTGTGTGCTGAGGATACTAAGTATAGTGTGCCACAC
ACAACAAGACCAAGGAAGCC

Downstream 100 bases:

>100_bases
ATCCTAATTTAGACTTAGTCTAAATACAGGATCCACAGAATCTGAGGGGGCCGATGGCCAGACGATTCCTCGGGCTGTTT
CCCCGAGTGCCCAGCGAGCC

Product: lysine decarboxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 467; Mature: 467

Protein sequence:

>467_residues
METTPLWDALRAVALASGTGFHTPGHNGGAGLPPALKHWPDWGRLDLTELAGLDNLHAPTGVIAHAQRLAAAVWGAERSW
FLVNGATAGIQAMLLAALGQGQKVLVPRNCHQSIVHALVLSGAVPVFVQPVWDRRWQLAHGLTATTVEAALAVHPDIRAV
VAVHPTYFGAVGETRAIARVAHAKGIALLVDAAHGAHLRFHPDLPECALAAGADLVVHSAHKTLPALTQAALLHQQGTLV
DPARVEMALNLLQTTSPSYLLMASLDLARAHMVRHGREQLGHILEMAHRLRHKLPFAVLGGDGTPGFDPTRLVIDVGEKG
WSGHAAETWLEQNAQVRAEMATHRHLVFILNSAHTEFDGEQLQASLLALATAQPTGATPPDLLPPPLPELRYSPREAFGR
SHRSVPLAAAAGLTSAADVCTYPPGVPVLLPGEVVAAQSVEYLGAAIDTGAETVGIDGRGHIRVTID

Sequences:

>Translated_467_residues
METTPLWDALRAVALASGTGFHTPGHNGGAGLPPALKHWPDWGRLDLTELAGLDNLHAPTGVIAHAQRLAAAVWGAERSW
FLVNGATAGIQAMLLAALGQGQKVLVPRNCHQSIVHALVLSGAVPVFVQPVWDRRWQLAHGLTATTVEAALAVHPDIRAV
VAVHPTYFGAVGETRAIARVAHAKGIALLVDAAHGAHLRFHPDLPECALAAGADLVVHSAHKTLPALTQAALLHQQGTLV
DPARVEMALNLLQTTSPSYLLMASLDLARAHMVRHGREQLGHILEMAHRLRHKLPFAVLGGDGTPGFDPTRLVIDVGEKG
WSGHAAETWLEQNAQVRAEMATHRHLVFILNSAHTEFDGEQLQASLLALATAQPTGATPPDLLPPPLPELRYSPREAFGR
SHRSVPLAAAAGLTSAADVCTYPPGVPVLLPGEVVAAQSVEYLGAAIDTGAETVGIDGRGHIRVTID
>Mature_467_residues
METTPLWDALRAVALASGTGFHTPGHNGGAGLPPALKHWPDWGRLDLTELAGLDNLHAPTGVIAHAQRLAAAVWGAERSW
FLVNGATAGIQAMLLAALGQGQKVLVPRNCHQSIVHALVLSGAVPVFVQPVWDRRWQLAHGLTATTVEAALAVHPDIRAV
VAVHPTYFGAVGETRAIARVAHAKGIALLVDAAHGAHLRFHPDLPECALAAGADLVVHSAHKTLPALTQAALLHQQGTLV
DPARVEMALNLLQTTSPSYLLMASLDLARAHMVRHGREQLGHILEMAHRLRHKLPFAVLGGDGTPGFDPTRLVIDVGEKG
WSGHAAETWLEQNAQVRAEMATHRHLVFILNSAHTEFDGEQLQASLLALATAQPTGATPPDLLPPPLPELRYSPREAFGR
SHRSVPLAAAAGLTSAADVCTYPPGVPVLLPGEVVAAQSVEYLGAAIDTGAETVGIDGRGHIRVTID

Specific function: Catalyzes the formation of agmatine from arginine [H]

COG id: COG1982

COG function: function code E; Arginine/lysine/ornithine decarboxylases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-I family [H]

Homologues:

Organism=Escherichia coli, GI221142684, Length=338, Percent_Identity=26.6272189349112, Blast_Score=101, Evalue=8e-23,
Organism=Escherichia coli, GI1790573, Length=322, Percent_Identity=25.1552795031056, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1786384, Length=328, Percent_Identity=27.4390243902439, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1786909, Length=311, Percent_Identity=26.6881028938907, Blast_Score=75, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000310
- InterPro:   IPR008286
- InterPro:   IPR015424
- InterPro:   IPR015421 [H]

Pfam domain/function: PF01276 OKR_DC_1; PF03711 OKR_DC_1_C [H]

EC number: =4.1.1.19 [H]

Molecular weight: Translated: 49370; Mature: 49370

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METTPLWDALRAVALASGTGFHTPGHNGGAGLPPALKHWPDWGRLDLTELAGLDNLHAPT
CCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCHHHHCCCCCCCCCH
GVIAHAQRLAAAVWGAERSWFLVNGATAGIQAMLLAALGQGQKVLVPRNCHQSIVHALVL
HHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHH
SGAVPVFVQPVWDRRWQLAHGLTATTVEAALAVHPDIRAVVAVHPTYFGAVGETRAIARV
HCCCCEEEECHHHHHHHHHCCCHHHHHHHHHEECCCCEEEEEECCHHHCCCCCHHHHHHH
AHAKGIALLVDAAHGAHLRFHPDLPECALAAGADLVVHSAHKTLPALTQAALLHQQGTLV
HHHCCEEEEEECCCCCEEEECCCCCHHHHHCCCHHEEECHHHHHHHHHHHHHHHCCCCCC
DPARVEMALNLLQTTSPSYLLMASLDLARAHMVRHGREQLGHILEMAHRLRHKLPFAVLG
CHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEC
GDGTPGFDPTRLVIDVGEKGWSGHAAETWLEQNAQVRAEMATHRHLVFILNSAHTEFDGE
CCCCCCCCCEEEEEECCCCCCCCCHHHHHHHCCHHHHHHHHCCCEEEEEEECCCCCCCHH
QLQASLLALATAQPTGATPPDLLPPPLPELRYSPREAFGRSHRSVPLAAAAGLTSAADVC
HHHHHHHHHEECCCCCCCCCCCCCCCCHHHCCCCHHHHCCCCCCCCHHHHCCCCCHHHHC
TYPPGVPVLLPGEVVAAQSVEYLGAAIDTGAETVGIDGRGHIRVTID
CCCCCCCEEECCCHHHHHHHHHHHHHHCCCCCEEECCCCCCEEEEEC
>Mature Secondary Structure
METTPLWDALRAVALASGTGFHTPGHNGGAGLPPALKHWPDWGRLDLTELAGLDNLHAPT
CCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCHHHHCCCCCCCCCH
GVIAHAQRLAAAVWGAERSWFLVNGATAGIQAMLLAALGQGQKVLVPRNCHQSIVHALVL
HHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHH
SGAVPVFVQPVWDRRWQLAHGLTATTVEAALAVHPDIRAVVAVHPTYFGAVGETRAIARV
HCCCCEEEECHHHHHHHHHCCCHHHHHHHHHEECCCCEEEEEECCHHHCCCCCHHHHHHH
AHAKGIALLVDAAHGAHLRFHPDLPECALAAGADLVVHSAHKTLPALTQAALLHQQGTLV
HHHCCEEEEEECCCCCEEEECCCCCHHHHHCCCHHEEECHHHHHHHHHHHHHHHCCCCCC
DPARVEMALNLLQTTSPSYLLMASLDLARAHMVRHGREQLGHILEMAHRLRHKLPFAVLG
CHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEC
GDGTPGFDPTRLVIDVGEKGWSGHAAETWLEQNAQVRAEMATHRHLVFILNSAHTEFDGE
CCCCCCCCCEEEEEECCCCCCCCCHHHHHHHCCHHHHHHHHCCCEEEEEEECCCCCCCHH
QLQASLLALATAQPTGATPPDLLPPPLPELRYSPREAFGRSHRSVPLAAAAGLTSAADVC
HHHHHHHHHEECCCCCCCCCCCCCCCCHHHCCCCHHHHCCCCCCCCHHHHCCCCCHHHHC
TYPPGVPVLLPGEVVAAQSVEYLGAAIDTGAETVGIDGRGHIRVTID
CCCCCCCEEECCCHHHHHHHHHHHHHHCCCCCEEECCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969500; 9384377; 1697575; 1936936 [H]