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The map label for this gene is sglT [H]

Identifier: 37523021

GI number: 37523021

Start: 3660479

End: 3662275

Strand: Direct

Name: sglT [H]

Synonym: glr3452

Alternate gene names: 37523021

Gene position: 3660479-3662275 (Clockwise)

Preceding gene: 37523018

Following gene: 37523024

Centisome position: 78.57

GC content: 62.88

Gene sequence:

>1797_bases
ATGCAACTGGAATGGATCGACTGGGCGATTATTGCTGCGTATTTTCTGGGCTCGCTGCTGATCGGGATTGCCTTCACCGG
GCGCGCCGGTAAAAGCCTGAGCGAATATTTTGTCTCCGGGCGCAACGTGCCCTGGTGGCTTGCGGGCACCTCGATGGTGG
CCACCACCTTCGCAGCCGACACCCCCCTGGCCGTCGCCGGTCTGGTGATCAAAAACGGCGTGGCGGCCAACTGGCTGTGG
TGGAGCTTCGTGATGGGCGGCATGCTCACGGTCTTTTTCTTTGCCCGCCTCTGGCGGCGCTCCGGGGTGCTCACCGACAT
CGAATTTACCGAGTTGCGCTACGGCGGCAAACCGGCGGCACTGCTGCGGGGCTTTCGCTCGCTCTATCTGGGGATCGCCA
TCAACTCGATCATCATGGGCTGGGTCACCCTGGCCATGGTCAAGATCCTCGGGCTGACTTTGGGGATCGACAAGTGGCAG
GCGGTGATTTTGTGCTTTGTCGTGACGGCGCTCTACACAACCCTTTCCGGGTTATGGGGGATCCTGGTCACCGACGCCTT
TCAATTTGTGATTGCGATGGTCGGTTGCATCGCCCTGGCTGTCTTTGGGCTGGAGGCGGTGGGGGGCATCGACGGCCTCA
AAGCGACCCTGGGCAGTCGCTTCGGCGACGCCGATCCGATCCTGGCGCTCACCCCGGCGGTCGATTCGCCCTGGATGCCC
ATTGCCACGTTCTTGATTTTGCTGAGTATCGGCTGGTGGGCGTCGTGGTATCCGGGAGCGGAACCGGGAGGGGGCGGCTA
TGTGGCCCAGCGGGTTTTCTCGGCGCGCAGCGAGCGCGATTCGCTTTTGGCGACGCTCTGGTTTACTGTTGCCCATTACG
CGCTCAGGCCCTGGCCGTGGATTGTGGTGGCGCTGGTGGCGATGGCCCTTTATCCGGGGCTGACTGAACCGAAGGCCGAC
CCTGAGACCGGCTACATCAAAGTGATGATCGACGTATTGCCCACCGGTTGGCGGGGATTGATGCTCGCCGCCTTCGCCGC
CGCCTACATGTCGACGATTTCGACCCACCTCAACTGGGGTACGTCCTATCTCATCAACGACTTTTACAAACGCTTCTTGC
GGCCGGAGGCTTCCGACAGCCACTACGTCTGGGCGGCGCGGCTTGCCACGGTGCTGGCGATGGTGCTGGCCGGGATCGCT
ACCCTCAACATCAATTCGATTAGCGGCGCCTGGCAGTTGCTGTTGGCCCTGGGTGCGGGAACCGGACCGGTCTATCTGCT
GCGCTGGTACTGGTGGCGCCTCAACGCCTGGTCGGAAATCTCAGCGCAACTGTGCGCGCTCGCAAGCTACGTTGTGCTCA
CTTACTTTTTGCCGGTGCAGATGCGCCTTGACACCAATGACCCCAACGATCTGGCCCTTTCGCTGGTGGTCTCGGTCGCC
GTCACCACGGTCTGCTGGCTGTCGGTCACTTTCTTGACCCAACCGGAGGCCCCGGCGGTGCTGGAGCGCTTTTACCGGCA
GGTGCGTCCGGAAGGACCGGGCTGGCGAGTCGTGCGCGAACGGTTGGGAGCCGGTCCGGGCGCTTCGTTGTGGCCCCTGG
CGTTTAACTGGCTGTGCGGAGTCGTGCTCGTCTATGGGGCGCTGTTCGGCGTGGGCAAATTGATCTTCAAAGAGTGGCTG
GCAGGTGGGCTGTATCTGGCGGTGAGTCTTGCAGCCGGAGCGCTGTTGGTCGTCACGTTCCAGGGCTTCTCGCCGGAACC
GGAGCCGCTGCCCGAGCCGCTCGCGGGCGAGGAGTGA

Upstream 100 bases:

>100_bases
GTACCCCCTTGCAGAATCGACGGCAGCGGCAGTAGGGTATCGGCGAGCACACTGGCGCTGCGTTTGCCCGTATTATGTCT
GCAGTTTTGATGCGCCGTTT

Downstream 100 bases:

>100_bases
CATTGCCCAACACGGATAACTTTTCGGCCGACGACCCGCGTTGGTGGGCAATGCACCAAGTCATTCCCCGATGTGGCTCG
GCGTCGGTGGTGTTTGATCT

Product: hypothetical protein

Products: NA

Alternate protein names: Na(+)/glucose symporter [H]

Number of amino acids: Translated: 598; Mature: 598

Protein sequence:

>598_residues
MQLEWIDWAIIAAYFLGSLLIGIAFTGRAGKSLSEYFVSGRNVPWWLAGTSMVATTFAADTPLAVAGLVIKNGVAANWLW
WSFVMGGMLTVFFFARLWRRSGVLTDIEFTELRYGGKPAALLRGFRSLYLGIAINSIIMGWVTLAMVKILGLTLGIDKWQ
AVILCFVVTALYTTLSGLWGILVTDAFQFVIAMVGCIALAVFGLEAVGGIDGLKATLGSRFGDADPILALTPAVDSPWMP
IATFLILLSIGWWASWYPGAEPGGGGYVAQRVFSARSERDSLLATLWFTVAHYALRPWPWIVVALVAMALYPGLTEPKAD
PETGYIKVMIDVLPTGWRGLMLAAFAAAYMSTISTHLNWGTSYLINDFYKRFLRPEASDSHYVWAARLATVLAMVLAGIA
TLNINSISGAWQLLLALGAGTGPVYLLRWYWWRLNAWSEISAQLCALASYVVLTYFLPVQMRLDTNDPNDLALSLVVSVA
VTTVCWLSVTFLTQPEAPAVLERFYRQVRPEGPGWRVVRERLGAGPGASLWPLAFNWLCGVVLVYGALFGVGKLIFKEWL
AGGLYLAVSLAAGALLVVTFQGFSPEPEPLPEPLAGEE

Sequences:

>Translated_598_residues
MQLEWIDWAIIAAYFLGSLLIGIAFTGRAGKSLSEYFVSGRNVPWWLAGTSMVATTFAADTPLAVAGLVIKNGVAANWLW
WSFVMGGMLTVFFFARLWRRSGVLTDIEFTELRYGGKPAALLRGFRSLYLGIAINSIIMGWVTLAMVKILGLTLGIDKWQ
AVILCFVVTALYTTLSGLWGILVTDAFQFVIAMVGCIALAVFGLEAVGGIDGLKATLGSRFGDADPILALTPAVDSPWMP
IATFLILLSIGWWASWYPGAEPGGGGYVAQRVFSARSERDSLLATLWFTVAHYALRPWPWIVVALVAMALYPGLTEPKAD
PETGYIKVMIDVLPTGWRGLMLAAFAAAYMSTISTHLNWGTSYLINDFYKRFLRPEASDSHYVWAARLATVLAMVLAGIA
TLNINSISGAWQLLLALGAGTGPVYLLRWYWWRLNAWSEISAQLCALASYVVLTYFLPVQMRLDTNDPNDLALSLVVSVA
VTTVCWLSVTFLTQPEAPAVLERFYRQVRPEGPGWRVVRERLGAGPGASLWPLAFNWLCGVVLVYGALFGVGKLIFKEWL
AGGLYLAVSLAAGALLVVTFQGFSPEPEPLPEPLAGEE
>Mature_598_residues
MQLEWIDWAIIAAYFLGSLLIGIAFTGRAGKSLSEYFVSGRNVPWWLAGTSMVATTFAADTPLAVAGLVIKNGVAANWLW
WSFVMGGMLTVFFFARLWRRSGVLTDIEFTELRYGGKPAALLRGFRSLYLGIAINSIIMGWVTLAMVKILGLTLGIDKWQ
AVILCFVVTALYTTLSGLWGILVTDAFQFVIAMVGCIALAVFGLEAVGGIDGLKATLGSRFGDADPILALTPAVDSPWMP
IATFLILLSIGWWASWYPGAEPGGGGYVAQRVFSARSERDSLLATLWFTVAHYALRPWPWIVVALVAMALYPGLTEPKAD
PETGYIKVMIDVLPTGWRGLMLAAFAAAYMSTISTHLNWGTSYLINDFYKRFLRPEASDSHYVWAARLATVLAMVLAGIA
TLNINSISGAWQLLLALGAGTGPVYLLRWYWWRLNAWSEISAQLCALASYVVLTYFLPVQMRLDTNDPNDLALSLVVSVA
VTTVCWLSVTFLTQPEAPAVLERFYRQVRPEGPGWRVVRERLGAGPGASLWPLAFNWLCGVVLVYGALFGVGKLIFKEWL
AGGLYLAVSLAAGALLVVTFQGFSPEPEPLPEPLAGEE

Specific function: Actively transports glucose into cells by Na(+) cotransport [H]

COG id: COG0591

COG function: function code ER; Na+/proline symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI14140236, Length=470, Percent_Identity=23.4042553191489, Blast_Score=108, Evalue=2e-23,
Organism=Homo sapiens, GI4507031, Length=473, Percent_Identity=24.9471458773784, Blast_Score=102, Evalue=8e-22,
Organism=Homo sapiens, GI17941285, Length=547, Percent_Identity=23.7659963436929, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI109659836, Length=470, Percent_Identity=24.2553191489362, Blast_Score=99, Evalue=9e-21,
Organism=Homo sapiens, GI109659839, Length=486, Percent_Identity=23.4567901234568, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI4507033, Length=419, Percent_Identity=25.2983293556086, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI157671931, Length=446, Percent_Identity=25.3363228699552, Blast_Score=87, Evalue=6e-17,
Organism=Homo sapiens, GI310128183, Length=453, Percent_Identity=24.5033112582781, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI110835708, Length=471, Percent_Identity=25.0530785562633, Blast_Score=80, Evalue=7e-15,
Organism=Homo sapiens, GI206597483, Length=408, Percent_Identity=23.7745098039216, Blast_Score=77, Evalue=5e-14,
Organism=Homo sapiens, GI206597487, Length=438, Percent_Identity=22.3744292237443, Blast_Score=70, Evalue=5e-12,
Organism=Escherichia coli, GI1790113, Length=475, Percent_Identity=23.5789473684211, Blast_Score=70, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 65271; Mature: 65271

Theoretical pI: Translated: 6.77; Mature: 6.77

Prosite motif: PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLEWIDWAIIAAYFLGSLLIGIAFTGRAGKSLSEYFVSGRNVPWWLAGTSMVATTFAAD
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCEEEECCHHHHHHHCCC
TPLAVAGLVIKNGVAANWLWWSFVMGGMLTVFFFARLWRRSGVLTDIEFTELRYGGKPAA
CCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCHHH
LLRGFRSLYLGIAINSIIMGWVTLAMVKILGLTLGIDKWQAVILCFVVTALYTTLSGLWG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
ILVTDAFQFVIAMVGCIALAVFGLEAVGGIDGLKATLGSRFGDADPILALTPAVDSPWMP
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCEEEECCCCCCCHH
IATFLILLSIGWWASWYPGAEPGGGGYVAQRVFSARSERDSLLATLWFTVAHYALRPWPW
HHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
IVVALVAMALYPGLTEPKADPETGYIKVMIDVLPTGWRGLMLAAFAAAYMSTISTHLNWG
HHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCC
TSYLINDFYKRFLRPEASDSHYVWAARLATVLAMVLAGIATLNINSISGAWQLLLALGAG
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCC
TGPVYLLRWYWWRLNAWSEISAQLCALASYVVLTYFLPVQMRLDTNDPNDLALSLVVSVA
CCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHH
VTTVCWLSVTFLTQPEAPAVLERFYRQVRPEGPGWRVVRERLGAGPGASLWPLAFNWLCG
HHHHHHHHHHEECCCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHH
VVLVYGALFGVGKLIFKEWLAGGLYLAVSLAAGALLVVTFQGFSPEPEPLPEPLAGEE
HHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCEEEEEEECCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MQLEWIDWAIIAAYFLGSLLIGIAFTGRAGKSLSEYFVSGRNVPWWLAGTSMVATTFAAD
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCEEEECCHHHHHHHCCC
TPLAVAGLVIKNGVAANWLWWSFVMGGMLTVFFFARLWRRSGVLTDIEFTELRYGGKPAA
CCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCHHH
LLRGFRSLYLGIAINSIIMGWVTLAMVKILGLTLGIDKWQAVILCFVVTALYTTLSGLWG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
ILVTDAFQFVIAMVGCIALAVFGLEAVGGIDGLKATLGSRFGDADPILALTPAVDSPWMP
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCEEEECCCCCCCHH
IATFLILLSIGWWASWYPGAEPGGGGYVAQRVFSARSERDSLLATLWFTVAHYALRPWPW
HHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
IVVALVAMALYPGLTEPKADPETGYIKVMIDVLPTGWRGLMLAAFAAAYMSTISTHLNWG
HHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCC
TSYLINDFYKRFLRPEASDSHYVWAARLATVLAMVLAGIATLNINSISGAWQLLLALGAG
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCC
TGPVYLLRWYWWRLNAWSEISAQLCALASYVVLTYFLPVQMRLDTNDPNDLALSLVVSVA
CCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHH
VTTVCWLSVTFLTQPEAPAVLERFYRQVRPEGPGWRVVRERLGAGPGASLWPLAFNWLCG
HHHHHHHHHHEECCCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHH
VVLVYGALFGVGKLIFKEWLAGGLYLAVSLAAGALLVVTFQGFSPEPEPLPEPLAGEE
HHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCEEEEEEECCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8652595; 10835424; 10757971 [H]