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The map label for this gene is rsgA2 [H]

Identifier: 37523015

GI number: 37523015

Start: 3654492

End: 3655550

Strand: Direct

Name: rsgA2 [H]

Synonym: glr3446

Alternate gene names: 37523015

Gene position: 3654492-3655550 (Clockwise)

Preceding gene: 37523014

Following gene: 37523017

Centisome position: 78.44

GC content: 67.23

Gene sequence:

>1059_bases
ATGAATTTGGATCCTTTCGGTTGGGATAGTTTTTTCGCGCAAGCTTTCGCGGGCTATCCCGAGAATGAATACGCTCCAGG
CCGGGTGATTGCCGAACACCGCGGCAGCTATGGGGTGGCCACAGAAATGGGGGAAGTGGCGGCGGCGGTCTCCGGACGCT
TGCGCCACGCGGCGCGCGGGCCGGCGGATTTTCCGGCGGTGGGCGATTGGGTGGTGCTTGAGCGCCGGGAGTTGCCCGGG
CACGGTCTGATCCAGGCGGTGCTGCCCAGAAAGAGCCGGTTCGCCCGGCGGGCGGCGGGCGGGCCGAGCGAGGCACAACT
GGTGGCGGCCAATGTGGAAGTGCTGTTCCTGGTGAGCGGTCTGGACGGCGACTTCAATGTGCGGCGCATCGAGCGCTATC
TGGTGCTCGCCTGGGAGTCCGGTGCCAACCCGGTGATCGTCCTCAACAAGGCCGACGTGTGCAGCGAGCTTGAGAAGCGG
GTGCAGGCGGTGGAGCGGGTGGCTGCGGGGGTGCCGGTGGTGGCGGTGAGCGCCGCTGCGGGCGGCCTGGAAAGCCTCGC
TTCCTGGCTTACCCCCGGCCGGACGGTGGCCCTTTTGGGCTCCAGCGGCGTGGGCAAATCGACGATTGCCAACCGGCTTT
TGGGCAACCCGGTTCAAGCAGTCCAGGGCGTGCGCGAGCACGACAGCCGCGGCCGGCACACGACGACTGCCCGCCAACTG
CTGCAACTGCCTGGGGGAGCCCTGCTCATCGACACCCCCGGCATGCGCGAGTTGCAGTTGTTGGCGGGAGAGGACAGTCT
GGAAGCGGCTTTTGCCGATGTTGAAGCGCTCGCCCGCCGGTGCCGCTTTCGCGATTGCAGCCACGCCAACGAACCCGGCT
GCGCGGTGCAGGCCGCCCTGCAGACAGGCGAACTGGAGGCGGCGCGGCTGGAAAGCTACCGCAAACTCCAGCGCGAAGCG
GCCTTCGAAGCGCGCAGGCAAGATCGCAGCGCCGCCCAGATCGAGAAGGAACGCTGGAAGCGAATCCATAAAGCCCAGCG
CGAGCGCCAAAAGCCCTAG

Upstream 100 bases:

>100_bases
GTAAGCCGCAGGGGTTCCTGTCGCTCATTCGTAGCATTCGGAATGCGTCGGCTTCCTCTGTGATCTTGCCGCAGTAGCAA
GATTCGCTTTGAGGAAAATC

Downstream 100 bases:

>100_bases
ACAGGTCTCGTATCAGATCCGCTTGGATTGTCATGTTTGACTGAGGTGCCAGGTGTCAGATGTCAGTGGGAACTTACTGG
CACCTGGCACCTGGCCTGAC

Product: ribosome-associated GTPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 352; Mature: 352

Protein sequence:

>352_residues
MNLDPFGWDSFFAQAFAGYPENEYAPGRVIAEHRGSYGVATEMGEVAAAVSGRLRHAARGPADFPAVGDWVVLERRELPG
HGLIQAVLPRKSRFARRAAGGPSEAQLVAANVEVLFLVSGLDGDFNVRRIERYLVLAWESGANPVIVLNKADVCSELEKR
VQAVERVAAGVPVVAVSAAAGGLESLASWLTPGRTVALLGSSGVGKSTIANRLLGNPVQAVQGVREHDSRGRHTTTARQL
LQLPGGALLIDTPGMRELQLLAGEDSLEAAFADVEALARRCRFRDCSHANEPGCAVQAALQTGELEAARLESYRKLQREA
AFEARRQDRSAAQIEKERWKRIHKAQRERQKP

Sequences:

>Translated_352_residues
MNLDPFGWDSFFAQAFAGYPENEYAPGRVIAEHRGSYGVATEMGEVAAAVSGRLRHAARGPADFPAVGDWVVLERRELPG
HGLIQAVLPRKSRFARRAAGGPSEAQLVAANVEVLFLVSGLDGDFNVRRIERYLVLAWESGANPVIVLNKADVCSELEKR
VQAVERVAAGVPVVAVSAAAGGLESLASWLTPGRTVALLGSSGVGKSTIANRLLGNPVQAVQGVREHDSRGRHTTTARQL
LQLPGGALLIDTPGMRELQLLAGEDSLEAAFADVEALARRCRFRDCSHANEPGCAVQAALQTGELEAARLESYRKLQREA
AFEARRQDRSAAQIEKERWKRIHKAQRERQKP
>Mature_352_residues
MNLDPFGWDSFFAQAFAGYPENEYAPGRVIAEHRGSYGVATEMGEVAAAVSGRLRHAARGPADFPAVGDWVVLERRELPG
HGLIQAVLPRKSRFARRAAGGPSEAQLVAANVEVLFLVSGLDGDFNVRRIERYLVLAWESGANPVIVLNKADVCSELEKR
VQAVERVAAGVPVVAVSAAAGGLESLASWLTPGRTVALLGSSGVGKSTIANRLLGNPVQAVQGVREHDSRGRHTTTARQL
LQLPGGALLIDTPGMRELQLLAGEDSLEAAFADVEALARRCRFRDCSHANEPGCAVQAALQTGELEAARLESYRKLQREA
AFEARRQDRSAAQIEKERWKRIHKAQRERQKP

Specific function: May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover [H]

COG id: COG1162

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 engC GTPase domain [H]

Homologues:

Organism=Escherichia coli, GI87082381, Length=256, Percent_Identity=30.859375, Blast_Score=123, Evalue=1e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010914
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004881 [H]

Pfam domain/function: PF03193 DUF258 [H]

EC number: NA

Molecular weight: Translated: 38122; Mature: 38122

Theoretical pI: Translated: 8.93; Mature: 8.93

Prosite motif: PS50936 ENGC_GTPASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLDPFGWDSFFAQAFAGYPENEYAPGRVIAEHRGSYGVATEMGEVAAAVSGRLRHAARG
CCCCCCCHHHHHHHHHCCCCCCCCCCCCEEHHCCCCCCHHHHHHHHHHHHHHHHHHHHCC
PADFPAVGDWVVLERRELPGHGLIQAVLPRKSRFARRAAGGPSEAQLVAANVEVLFLVSG
CCCCCCCCCEEEEECCCCCCCHHHHHHHCHHHHHHHHHCCCCCCCEEEEECEEEEEEEEC
LDGDFNVRRIERYLVLAWESGANPVIVLNKADVCSELEKRVQAVERVAAGVPVVAVSAAA
CCCCCHHHEEEEEEEEEEECCCCCEEEEECHHHHHHHHHHHHHHHHHHCCCCEEEEHHHH
GGLESLASWLTPGRTVALLGSSGVGKSTIANRLLGNPVQAVQGVREHDSRGRHTTTARQL
CCHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHH
LQLPGGALLIDTPGMRELQLLAGEDSLEAAFADVEALARRCRFRDCSHANEPGCAVQAAL
HHCCCCEEEECCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
QTGELEAARLESYRKLQREAAFEARRQDRSAAQIEKERWKRIHKAQRERQKP
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNLDPFGWDSFFAQAFAGYPENEYAPGRVIAEHRGSYGVATEMGEVAAAVSGRLRHAARG
CCCCCCCHHHHHHHHHCCCCCCCCCCCCEEHHCCCCCCHHHHHHHHHHHHHHHHHHHHCC
PADFPAVGDWVVLERRELPGHGLIQAVLPRKSRFARRAAGGPSEAQLVAANVEVLFLVSG
CCCCCCCCCEEEEECCCCCCCHHHHHHHCHHHHHHHHHCCCCCCCEEEEECEEEEEEEEC
LDGDFNVRRIERYLVLAWESGANPVIVLNKADVCSELEKRVQAVERVAAGVPVVAVSAAA
CCCCCHHHEEEEEEEEEEECCCCCEEEEECHHHHHHHHHHHHHHHHHHCCCCEEEEHHHH
GGLESLASWLTPGRTVALLGSSGVGKSTIANRLLGNPVQAVQGVREHDSRGRHTTTARQL
CCHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHH
LQLPGGALLIDTPGMRELQLLAGEDSLEAAFADVEALARRCRFRDCSHANEPGCAVQAAL
HHCCCCEEEECCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
QTGELEAARLESYRKLQREAAFEARRQDRSAAQIEKERWKRIHKAQRERQKP
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: GTP [C]

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]