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The map label for this gene is aphA [H]

Identifier: 37523001

GI number: 37523001

Start: 3633338

End: 3635038

Strand: Direct

Name: aphA [H]

Synonym: glr3432

Alternate gene names: 37523001

Gene position: 3633338-3635038 (Clockwise)

Preceding gene: 37522997

Following gene: 37523002

Centisome position: 77.99

GC content: 64.32

Gene sequence:

>1701_bases
ATGTTTTGCACGTCGGGCCGCCTTCGCCAGTCCATTGTGCACAGACAGCTAATAGAGTCGAGGATGGACCAGGAAGCTCA
AGAGCGACTATGCCCCAACGCAAAGCATCTGCATTTTGCAATGGAGGCCGCCCACCTGGGTGTTTGGGATTGGAATGCCC
AAGAAAATACGGTGTTTTGTTCCGATAACGTTGAGCGGATGTTGGGTCTGGCTGCGGGCACATTTGCAGGCACCCTCGAA
GCGTTTCTCGCCTGCGTGCACCCGGAAGACCGCGCTCCCGTCGCGGCTGGGATTGCCGCGGTGCTTGCCCAAAAGCGGGA
GCCGCACGGCGAATTTCGGGTCGTCCACCCGGTGGGTGAGGTGCGCTGGCTGGCAGCCCAGGGCCGGCTGGTCTTTGGCG
ACGACGGTGCGGTGGTGCGAGTGCTCGGCATCGTGGCGGACATCACCGAACGACGGCGGACCGAGGCGGAGTTGCAGCGG
CAGAACCGGCGCATCCGCCTTTTCTCGGACATTGCCCTGAAAATTCGCCAGTCTTTACAACTGGAGGACATCCTGCGCAC
GTCCGTCGACGAGGTGCAAAAGCTGCTGGCTGCCGACCGGGTGCTCATCTTCCGGCTGTGGGCGGACGGCACCGGCAAGG
TGGTGCAGGAGGCGGTGCTGGAGAGCTGGCCGGCGGCGCTCGGGCAGAACATCCTCGATCCGTGCTTTCGAGACGGTTAC
CAGGAGCAGTACCGCCGGGGGCGCATCGGCGCCATCGCCGACATCGAGACGGCGCCCATCCAGCCCTGCCATGCCGATTT
TTTGCGGCGCTTCGCGGTGCGCGCCAATCTGGTGGTGCCCATTTTGCAGCGCGAGCAGCTGTGGGGTCTGCTCATCGCCC
ACCAGTGCAGCGCCCCCCGCCAGTGGAGCACTTTTGAGACGGAGTTGCTGTTGCAGTTGGCCGACCAGATGGGCATCGCC
CTCGCCCAGGCGCAACTGTTGGAGCAAGAGACCCAGCAGCGCCGGGAGCTGGCCCGCTCCAACACCGACCTCGAGCAGTT
CGCCTACGTCGCCTCCCACGATCTGCAGGAGCCCTTGCGGATGATCGGCAGCTACCTGCAACTGTTGGAGCAGCGCTACC
AGGACAAGCTCGATCCGGATGCCCAGGAATTCATCGGCTACGCCGTCGATGGGGCGCGCTGGATGCAGACGCTCATCAAC
GATCTGCTGGCCTACTCGCGCGTCGGCATCCGCGCCGCACCACCCGGCCGCATCGACGCGAGCGCCGTTCTCGAGAACGC
CCTGGCCAACTTAAAACCAACCATCGAAAATAGCGGCGCCACCGTCAGCCGCGAAGCGCTGCCCAAGGTGATCGCCGATG
CCACCCAGCTTGCCCAGGTCTTCCAGAATCTGGTGGGCAATGCGCTCAAGTTCCATGGCCCCGAGCCGCCGCAGATACAC
ATCGGCGCGGCGCCCGCTGCAGGGGAGTGGGTCTTCTCGGTGGCCGACAACGGCATCGGCATCGAAGCGCCTTACCGCGA
GCGCATCTTTGCCGTCTTTCGGCGGCTGCACCCCCGCGGCGGCTACGCCGGCACCGGCATCGGCCTGGCTATCTGCAAAA
AAATTGTCGAGCGCCACGGCGGGCGCATCTGGGTCGAGTCGCAGCCCGGCCGCGGATCGACATTTTTCTTTACCGTTCCG
GAGCCCACAGGTGATCTATGA

Upstream 100 bases:

>100_bases
GATCGCATGGATCAGGCTGTCGGCGTGGCTGGTAGTGAAAAGTTACGGTAAGCTTAAGGTTCCCAACGGAATCGTATTTG
TCTTATCTTGATATCGGGGC

Downstream 100 bases:

>100_bases
GCAGTGCCGCCGCCCCGAACCGTCCCATCGAAGTGCTGCTGGTCGAGGATAATCCCGGCGATGTGCGCTTGACCCGCATT
GCCCTCGCCGAAGGTCTGAT

Product: two-component sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 566; Mature: 566

Protein sequence:

>566_residues
MFCTSGRLRQSIVHRQLIESRMDQEAQERLCPNAKHLHFAMEAAHLGVWDWNAQENTVFCSDNVERMLGLAAGTFAGTLE
AFLACVHPEDRAPVAAGIAAVLAQKREPHGEFRVVHPVGEVRWLAAQGRLVFGDDGAVVRVLGIVADITERRRTEAELQR
QNRRIRLFSDIALKIRQSLQLEDILRTSVDEVQKLLAADRVLIFRLWADGTGKVVQEAVLESWPAALGQNILDPCFRDGY
QEQYRRGRIGAIADIETAPIQPCHADFLRRFAVRANLVVPILQREQLWGLLIAHQCSAPRQWSTFETELLLQLADQMGIA
LAQAQLLEQETQQRRELARSNTDLEQFAYVASHDLQEPLRMIGSYLQLLEQRYQDKLDPDAQEFIGYAVDGARWMQTLIN
DLLAYSRVGIRAAPPGRIDASAVLENALANLKPTIENSGATVSREALPKVIADATQLAQVFQNLVGNALKFHGPEPPQIH
IGAAPAAGEWVFSVADNGIGIEAPYRERIFAVFRRLHPRGGYAGTGIGLAICKKIVERHGGRIWVESQPGRGSTFFFTVP
EPTGDL

Sequences:

>Translated_566_residues
MFCTSGRLRQSIVHRQLIESRMDQEAQERLCPNAKHLHFAMEAAHLGVWDWNAQENTVFCSDNVERMLGLAAGTFAGTLE
AFLACVHPEDRAPVAAGIAAVLAQKREPHGEFRVVHPVGEVRWLAAQGRLVFGDDGAVVRVLGIVADITERRRTEAELQR
QNRRIRLFSDIALKIRQSLQLEDILRTSVDEVQKLLAADRVLIFRLWADGTGKVVQEAVLESWPAALGQNILDPCFRDGY
QEQYRRGRIGAIADIETAPIQPCHADFLRRFAVRANLVVPILQREQLWGLLIAHQCSAPRQWSTFETELLLQLADQMGIA
LAQAQLLEQETQQRRELARSNTDLEQFAYVASHDLQEPLRMIGSYLQLLEQRYQDKLDPDAQEFIGYAVDGARWMQTLIN
DLLAYSRVGIRAAPPGRIDASAVLENALANLKPTIENSGATVSREALPKVIADATQLAQVFQNLVGNALKFHGPEPPQIH
IGAAPAAGEWVFSVADNGIGIEAPYRERIFAVFRRLHPRGGYAGTGIGLAICKKIVERHGGRIWVESQPGRGSTFFFTVP
EPTGDL
>Mature_566_residues
MFCTSGRLRQSIVHRQLIESRMDQEAQERLCPNAKHLHFAMEAAHLGVWDWNAQENTVFCSDNVERMLGLAAGTFAGTLE
AFLACVHPEDRAPVAAGIAAVLAQKREPHGEFRVVHPVGEVRWLAAQGRLVFGDDGAVVRVLGIVADITERRRTEAELQR
QNRRIRLFSDIALKIRQSLQLEDILRTSVDEVQKLLAADRVLIFRLWADGTGKVVQEAVLESWPAALGQNILDPCFRDGY
QEQYRRGRIGAIADIETAPIQPCHADFLRRFAVRANLVVPILQREQLWGLLIAHQCSAPRQWSTFETELLLQLADQMGIA
LAQAQLLEQETQQRRELARSNTDLEQFAYVASHDLQEPLRMIGSYLQLLEQRYQDKLDPDAQEFIGYAVDGARWMQTLIN
DLLAYSRVGIRAAPPGRIDASAVLENALANLKPTIENSGATVSREALPKVIADATQLAQVFQNLVGNALKFHGPEPPQIH
IGAAPAAGEWVFSVADNGIGIEAPYRERIFAVFRRLHPRGGYAGTGIGLAICKKIVERHGGRIWVESQPGRGSTFFFTVP
EPTGDL

Specific function: Photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=247, Percent_Identity=29.1497975708502, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1786912, Length=297, Percent_Identity=27.6094276094276, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1789149, Length=229, Percent_Identity=28.82096069869, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI145693157, Length=241, Percent_Identity=28.2157676348548, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1788549, Length=242, Percent_Identity=28.099173553719, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1790436, Length=244, Percent_Identity=27.8688524590164, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1788713, Length=235, Percent_Identity=26.8085106382979, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1786600, Length=229, Percent_Identity=30.1310043668122, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI87081816, Length=262, Percent_Identity=27.0992366412214, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI87082128, Length=232, Percent_Identity=26.2931034482759, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1788393, Length=268, Percent_Identity=26.865671641791, Blast_Score=63, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR013654
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01590 GAF; PF02518 HATPase_c; PF00512 HisKA; PF08446 PAS_2; PF00360 Phytochrome [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 63035; Mature: 63035

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN ; PS50046 PHYTOCHROME_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFCTSGRLRQSIVHRQLIESRMDQEAQERLCPNAKHLHFAMEAAHLGVWDWNAQENTVFC
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCEEECCCCCCEEEE
SDNVERMLGLAAGTFAGTLEAFLACVHPEDRAPVAAGIAAVLAQKREPHGEFRVVHPVGE
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCC
VRWLAAQGRLVFGDDGAVVRVLGIVADITERRRTEAELQRQNRRIRLFSDIALKIRQSLQ
EEEEEECCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHCC
LEDILRTSVDEVQKLLAADRVLIFRLWADGTGKVVQEAVLESWPAALGQNILDPCFRDGY
HHHHHHHHHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHHHHHHCHHHHHHHHHCCH
QEQYRRGRIGAIADIETAPIQPCHADFLRRFAVRANLVVPILQREQLWGLLIAHQCSAPR
HHHHHCCCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
QWSTFETELLLQLADQMGIALAQAQLLEQETQQRRELARSNTDLEQFAYVASHDLQEPLR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
MIGSYLQLLEQRYQDKLDPDAQEFIGYAVDGARWMQTLINDLLAYSRVGIRAAPPGRIDA
HHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCH
SAVLENALANLKPTIENSGATVSREALPKVIADATQLAQVFQNLVGNALKFHGPEPPQIH
HHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCEEE
IGAAPAAGEWVFSVADNGIGIEAPYRERIFAVFRRLHPRGGYAGTGIGLAICKKIVERHG
EECCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCC
GRIWVESQPGRGSTFFFTVPEPTGDL
CEEEEECCCCCCCEEEEECCCCCCCC
>Mature Secondary Structure
MFCTSGRLRQSIVHRQLIESRMDQEAQERLCPNAKHLHFAMEAAHLGVWDWNAQENTVFC
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCEEECCCCCCEEEE
SDNVERMLGLAAGTFAGTLEAFLACVHPEDRAPVAAGIAAVLAQKREPHGEFRVVHPVGE
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCC
VRWLAAQGRLVFGDDGAVVRVLGIVADITERRRTEAELQRQNRRIRLFSDIALKIRQSLQ
EEEEEECCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHCC
LEDILRTSVDEVQKLLAADRVLIFRLWADGTGKVVQEAVLESWPAALGQNILDPCFRDGY
HHHHHHHHHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHHHHHHCHHHHHHHHHCCH
QEQYRRGRIGAIADIETAPIQPCHADFLRRFAVRANLVVPILQREQLWGLLIAHQCSAPR
HHHHHCCCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
QWSTFETELLLQLADQMGIALAQAQLLEQETQQRRELARSNTDLEQFAYVASHDLQEPLR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
MIGSYLQLLEQRYQDKLDPDAQEFIGYAVDGARWMQTLINDLLAYSRVGIRAAPPGRIDA
HHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCH
SAVLENALANLKPTIENSGATVSREALPKVIADATQLAQVFQNLVGNALKFHGPEPPQIH
HHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCEEE
IGAAPAAGEWVFSVADNGIGIEAPYRERIFAVFRRLHPRGGYAGTGIGLAICKKIVERHG
EECCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCC
GRIWVESQPGRGSTFFFTVPEPTGDL
CEEEEECCCCCCCEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]