Click here to switch to the map view.

The map label for this gene is ubiA [H]

Identifier: 37522997

GI number: 37522997

Start: 3629421

End: 3630299

Strand: Direct

Name: ubiA [H]

Synonym: gvip469

Alternate gene names: 37522997

Gene position: 3629421-3630299 (Clockwise)

Preceding gene: 37522996

Following gene: 37523001

Centisome position: 77.9

GC content: 64.16

Gene sequence:

>879_bases
ATGAGTACCGCCCCCACCGACTGGCGCGCCAAAGCCGACGCTGTCTTCCGCCTATTGCGCTGGGACAAACCGGCCGGCCG
GCTTATCTTGATGATCCCCGCGCTCTGGGGAGTCTTCGCCGCCGCCGGGGGTTCCCCCTCGCCGCTGTTGGTGCTGGTGA
TGGTAGTAGGCACCATCGCCACCAGTGCCGCCGGTTGCGTCATCAACGACCTGTGGGATCGCGACATCGATCCGCTCGTC
GAGCGCACCCGCGCTCGGCCCCTCGCCAGCCGCGAACTGGCCGTGCCGGTAGCGGTGGTCACTTTCGCGGTCTCGCTGCT
GTGCGCCTGGGGGCTGACCTTTTTTCTCAACCCCTTCACCTTCTGGTTGTGCGTTGCCGCCGTGCCGGTGATTGCCCTCT
ATCCGGGGGCCAAGCGCGTCTTCCCGGTGCCGCAACTGGTCCTCTCGCTGGCCTGGGGGTTTGCCGCGCTCATCTCCTGG
TCGGCAGTGACCGGCGGCCTGGAGACCCCCGCCTGGTGGCTATGGGGAGCGACGGTGCTGTGGACCCTTGGCTTTGACAC
GGTCTATGCCCTTTCGGACCGCGAGGACGACCTCAAAATCGGGATCAACTCGAGTGCTATCTTTTTTGGCCGCTTCACCC
CCGAGGCGATCGCCGCATTTTTTGCCGGGGCCGCTCTGTGCCTGGCGGTGGTAGGCTACCAGCTGGAACTGGGATCGATT
TTTTATGTGTGTTTGATCGTCGCCACCCTCTTCTGGTGGCGCGAGTACCGCTCGCTGGTGACCGGCGACGATCCGGCCCG
CTTTAACCGCATCTTCAATGAAAACGTCACCGTCGGTTTTGTCATCCTGACGGGGCTCATCGGCGGGACGTTGATCTGA

Upstream 100 bases:

>100_bases
CCTTCGAGGTGGCGGGACCCGTCAACCAGACCGGCTCGCTGCGCGATTTGCGTTGGGTCGACGAACCGGCACCCATCGAA
GAGCGCCCCGCCTCGACACC

Downstream 100 bases:

>100_bases
GTGCAAAAGGTCCGGCAGCGAACTGAACCGGGTGGGTAGTTTCTAACTGCGACTAATCATGGCGGATATGGGCTTCGCCC
TGGGCCAGCAAATTGAGCAC

Product: 4-hydroxybenzoate polyprenyltransferase

Products: NA

Alternate protein names: 4-HB polyprenyltransferase [H]

Number of amino acids: Translated: 292; Mature: 291

Protein sequence:

>292_residues
MSTAPTDWRAKADAVFRLLRWDKPAGRLILMIPALWGVFAAAGGSPSPLLVLVMVVGTIATSAAGCVINDLWDRDIDPLV
ERTRARPLASRELAVPVAVVTFAVSLLCAWGLTFFLNPFTFWLCVAAVPVIALYPGAKRVFPVPQLVLSLAWGFAALISW
SAVTGGLETPAWWLWGATVLWTLGFDTVYALSDREDDLKIGINSSAIFFGRFTPEAIAAFFAGAALCLAVVGYQLELGSI
FYVCLIVATLFWWREYRSLVTGDDPARFNRIFNENVTVGFVILTGLIGGTLI

Sequences:

>Translated_292_residues
MSTAPTDWRAKADAVFRLLRWDKPAGRLILMIPALWGVFAAAGGSPSPLLVLVMVVGTIATSAAGCVINDLWDRDIDPLV
ERTRARPLASRELAVPVAVVTFAVSLLCAWGLTFFLNPFTFWLCVAAVPVIALYPGAKRVFPVPQLVLSLAWGFAALISW
SAVTGGLETPAWWLWGATVLWTLGFDTVYALSDREDDLKIGINSSAIFFGRFTPEAIAAFFAGAALCLAVVGYQLELGSI
FYVCLIVATLFWWREYRSLVTGDDPARFNRIFNENVTVGFVILTGLIGGTLI
>Mature_291_residues
STAPTDWRAKADAVFRLLRWDKPAGRLILMIPALWGVFAAAGGSPSPLLVLVMVVGTIATSAAGCVINDLWDRDIDPLVE
RTRARPLASRELAVPVAVVTFAVSLLCAWGLTFFLNPFTFWLCVAAVPVIALYPGAKRVFPVPQLVLSLAWGFAALISWS
AVTGGLETPAWWLWGATVLWTLGFDTVYALSDREDDLKIGINSSAIFFGRFTPEAIAAFFAGAALCLAVVGYQLELGSIF
YVCLIVATLFWWREYRSLVTGDDPARFNRIFNENVTVGFVILTGLIGGTLI

Specific function: Synthesis of 3-octaprenyl-4-hydroxybenzoate [H]

COG id: COG0382

COG function: function code H; 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI260656052, Length=279, Percent_Identity=31.5412186379928, Blast_Score=134, Evalue=1e-31,
Organism=Escherichia coli, GI1790473, Length=278, Percent_Identity=35.6115107913669, Blast_Score=150, Evalue=8e-38,
Organism=Caenorhabditis elegans, GI17553718, Length=282, Percent_Identity=33.6879432624113, Blast_Score=140, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI32565247, Length=285, Percent_Identity=31.9298245614035, Blast_Score=122, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17553720, Length=341, Percent_Identity=27.5659824046921, Blast_Score=107, Evalue=9e-24,
Organism=Caenorhabditis elegans, GI32565245, Length=135, Percent_Identity=37.037037037037, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI32565243, Length=135, Percent_Identity=37.037037037037, Blast_Score=74, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6324370, Length=290, Percent_Identity=30.6896551724138, Blast_Score=109, Evalue=5e-25,
Organism=Drosophila melanogaster, GI21355567, Length=279, Percent_Identity=34.4086021505376, Blast_Score=145, Evalue=3e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006370
- InterPro:   IPR000537 [H]

Pfam domain/function: PF01040 UbiA [H]

EC number: 2.5.1.-

Molecular weight: Translated: 31751; Mature: 31620

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTAPTDWRAKADAVFRLLRWDKPAGRLILMIPALWGVFAAAGGSPSPLLVLVMVVGTIA
CCCCCCCHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
TSAAGCVINDLWDRDIDPLVERTRARPLASRELAVPVAVVTFAVSLLCAWGLTFFLNPFT
HHHCCHHHHHHHCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FWLCVAAVPVIALYPGAKRVFPVPQLVLSLAWGFAALISWSAVTGGLETPAWWLWGATVL
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
WTLGFDTVYALSDREDDLKIGINSSAIFFGRFTPEAIAAFFAGAALCLAVVGYQLELGSI
HHHCCHHEEEECCCCCCEEEECCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
FYVCLIVATLFWWREYRSLVTGDDPARFNRIFNENVTVGFVILTGLIGGTLI
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
STAPTDWRAKADAVFRLLRWDKPAGRLILMIPALWGVFAAAGGSPSPLLVLVMVVGTIA
CCCCCCHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
TSAAGCVINDLWDRDIDPLVERTRARPLASRELAVPVAVVTFAVSLLCAWGLTFFLNPFT
HHHCCHHHHHHHCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FWLCVAAVPVIALYPGAKRVFPVPQLVLSLAWGFAALISWSAVTGGLETPAWWLWGATVL
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
WTLGFDTVYALSDREDDLKIGINSSAIFFGRFTPEAIAAFFAGAALCLAVVGYQLELGSI
HHHCCHHEEEECCCCCCEEEECCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
FYVCLIVATLFWWREYRSLVTGDDPARFNRIFNENVTVGFVILTGLIGGTLI
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA