| Definition | Gloeobacter violaceus PCC 7421 chromosome, complete genome. |
|---|---|
| Accession | NC_005125 |
| Length | 4,659,019 |
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The map label for this gene is hisC [H]
Identifier: 37522992
GI number: 37522992
Start: 3621661
End: 3622788
Strand: Reverse
Name: hisC [H]
Synonym: gvip468
Alternate gene names: 37522992
Gene position: 3622788-3621661 (Counterclockwise)
Preceding gene: 37522993
Following gene: 37522985
Centisome position: 77.76
GC content: 66.22
Gene sequence:
>1128_bases GTGATTCAAACACCCCTTCCTGCCCACGGCGGCGACCGCCAATGGGCGGCACGGATCGCCCGCTGCCGCATCGAAGAACT TGTGGATTTCTCTGCCAGCATCAACCCCCTCGGTCCCCCCCCTGGGGTACAGGCCGCCTACGGCGAGGGTTTTGCCGATC TATTGCATTACCCCGCTCCCCACGGCAGCGACCTGCAATCGGCCCTCGCCGCCCGCCTGGGAATCGAGCCCGAGCGCATC GTCTGCGGCAACGGGGCGGCGGAACTGCTCACCTGGGCGGGCCGCGAGTGCGCCCGCGCCGGACGGACCGTGCTACCGAT ACCCGCTTTTGGCGATTACCGCCGCGCCCTCGCCGCCTTTGACGCCCCGTATATTTCTGTACCACTCGCAGCCGATTTTT CACTGCCAAAGACACTGCCGCCGGGCGATGCGGTGATGCTCGCCAATCCCCACAATCCCTCCGGCTATCTCTACTCCCCG ACCGCCCTCGCAGCGTTGTTCGACCGCTTCAAGCTGCTTATCTTCGACGAAGCGTTCATCGATTTTCTCGACGACCCGGC GGCATTTTCGGCGCTTTGCGGCCCCGCGCACCCGGGGCTGATCGTGATTCGCTCGCTCACCAAATTCTATAGTTTGCCGG GGTTACGGCTGGGCTACGCCGTGCTGCCGGTGGCGATGGCGGCGCGCTGGCAAGCCTGGCGCGATCCATGGCCTGTCAAT GCCCTTGCCCAACACCTGGGAGTAGCGGCCCTGGCGGATCTCGATTTCGAGCGGCGCACCCGCGCCTGGCTTGGCCCGGC CCGCTCCCGCCTCGCCGCGGGCCTTGCGCTCCTGCCGGGGCTGACGGTCCTGCCGGGGGCGGCCAACTTCTTGCTGGTGC AGAGCGCCGCCTCGGCGGTGCACCTGCAGGCCGAATTACTGCGCCGCCATCGCCTGCTCATCCGCCACTGCACCAGCTAC GACGGTCTTGGCGAGCGTTATTTTCGGGTGGCGGTGCGCGGCGAATCCGAGAATGATCTGCTCACTGGCGCTCTAGCCGA GATTCTTGCTAAAACCCCAGCGACGAGCCGAGTCGACGGCTGCGCCAGTAGCCCGCCGCCATCAACAGACCCAGTGCATC CAGAGTAA
Upstream 100 bases:
>100_bases GACCCGCGAGAAGATGACCATCGCCGCGACGACCGTGCCGGCTTTTTCGGCGGGCAAGCAGTTTCGAGAAGCCGTCTCCG GTTCTGCCCAAGCGGACTAA
Downstream 100 bases:
>100_bases GCAGCGTCGCGGCCCAGTCGTCCCGGGCGGCCAGCAAGCTCACCCCGCCCCACCCCAGCAGCGAGACGAATTCTAAAATC CCGAGCATCGGATCTCCGCC
Product: threonine-phosphate decarboxylase
Products: NA
Alternate protein names: L-threonine-O-3-phosphate decarboxylase [H]
Number of amino acids: Translated: 375; Mature: 375
Protein sequence:
>375_residues MIQTPLPAHGGDRQWAARIARCRIEELVDFSASINPLGPPPGVQAAYGEGFADLLHYPAPHGSDLQSALAARLGIEPERI VCGNGAAELLTWAGRECARAGRTVLPIPAFGDYRRALAAFDAPYISVPLAADFSLPKTLPPGDAVMLANPHNPSGYLYSP TALAALFDRFKLLIFDEAFIDFLDDPAAFSALCGPAHPGLIVIRSLTKFYSLPGLRLGYAVLPVAMAARWQAWRDPWPVN ALAQHLGVAALADLDFERRTRAWLGPARSRLAAGLALLPGLTVLPGAANFLLVQSAASAVHLQAELLRRHRLLIRHCTSY DGLGERYFRVAVRGESENDLLTGALAEILAKTPATSRVDGCASSPPPSTDPVHPE
Sequences:
>Translated_375_residues MIQTPLPAHGGDRQWAARIARCRIEELVDFSASINPLGPPPGVQAAYGEGFADLLHYPAPHGSDLQSALAARLGIEPERI VCGNGAAELLTWAGRECARAGRTVLPIPAFGDYRRALAAFDAPYISVPLAADFSLPKTLPPGDAVMLANPHNPSGYLYSP TALAALFDRFKLLIFDEAFIDFLDDPAAFSALCGPAHPGLIVIRSLTKFYSLPGLRLGYAVLPVAMAARWQAWRDPWPVN ALAQHLGVAALADLDFERRTRAWLGPARSRLAAGLALLPGLTVLPGAANFLLVQSAASAVHLQAELLRRHRLLIRHCTSY DGLGERYFRVAVRGESENDLLTGALAEILAKTPATSRVDGCASSPPPSTDPVHPE >Mature_375_residues MIQTPLPAHGGDRQWAARIARCRIEELVDFSASINPLGPPPGVQAAYGEGFADLLHYPAPHGSDLQSALAARLGIEPERI VCGNGAAELLTWAGRECARAGRTVLPIPAFGDYRRALAAFDAPYISVPLAADFSLPKTLPPGDAVMLANPHNPSGYLYSP TALAALFDRFKLLIFDEAFIDFLDDPAAFSALCGPAHPGLIVIRSLTKFYSLPGLRLGYAVLPVAMAARWQAWRDPWPVN ALAQHLGVAALADLDFERRTRAWLGPARSRLAAGLALLPGLTVLPGAANFLLVQSAASAVHLQAELLRRHRLLIRHCTSY DGLGERYFRVAVRGESENDLLTGALAEILAKTPATSRVDGCASSPPPSTDPVHPE
Specific function: Decarboxylates L-threonine-O-3-phosphate to yield (R)-1- amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin [H]
COG id: COG0079
COG function: function code E; Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family [H]
Homologues:
None
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR004839 - InterPro: IPR005860 - InterPro: IPR004838 - InterPro: IPR015424 - InterPro: IPR015421 - InterPro: IPR015422 [H]
Pfam domain/function: PF00155 Aminotran_1_2 [H]
EC number: =4.1.1.81 [H]
Molecular weight: Translated: 40161; Mature: 40161
Theoretical pI: Translated: 7.05; Mature: 7.05
Prosite motif: PS00105 AA_TRANSFER_CLASS_1
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.6 %Cys (Translated Protein) 0.8 %Met (Translated Protein) 2.4 %Cys+Met (Translated Protein) 1.6 %Cys (Mature Protein) 0.8 %Met (Mature Protein) 2.4 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MIQTPLPAHGGDRQWAARIARCRIEELVDFSASINPLGPPPGVQAAYGEGFADLLHYPAP CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHCCCHHHHHHCCCC HGSDLQSALAARLGIEPERIVCGNGAAELLTWAGRECARAGRTVLPIPAFGDYRRALAAF CCCHHHHHHHHHHCCCCCEEEECCCHHHHHHHHCHHHHHCCCEEEECCCCHHHHHHHHHH DAPYISVPLAADFSLPKTLPPGDAVMLANPHNPSGYLYSPTALAALFDRFKLLIFDEAFI CCCCEEEEEECCCCCCCCCCCCCEEEEECCCCCCCEEECHHHHHHHHHHHHHHHHHHHHH DFLDDPAAFSALCGPAHPGLIVIRSLTKFYSLPGLRLGYAVLPVAMAARWQAWRDPWPVN HHHCCHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCHH ALAQHLGVAALADLDFERRTRAWLGPARSRLAAGLALLPGLTVLPGAANFLLVQSAASAV HHHHHHCHHHHHHCCHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH HLQAELLRRHRLLIRHCTSYDGLGERYFRVAVRGESENDLLTGALAEILAKTPATSRVDG HHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCC CASSPPPSTDPVHPE CCCCCCCCCCCCCCC >Mature Secondary Structure MIQTPLPAHGGDRQWAARIARCRIEELVDFSASINPLGPPPGVQAAYGEGFADLLHYPAP CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHCCCHHHHHHCCCC HGSDLQSALAARLGIEPERIVCGNGAAELLTWAGRECARAGRTVLPIPAFGDYRRALAAF CCCHHHHHHHHHHCCCCCEEEECCCHHHHHHHHCHHHHHCCCEEEECCCCHHHHHHHHHH DAPYISVPLAADFSLPKTLPPGDAVMLANPHNPSGYLYSPTALAALFDRFKLLIFDEAFI CCCCEEEEEECCCCCCCCCCCCCEEEEECCCCCCCEEECHHHHHHHHHHHHHHHHHHHHH DFLDDPAAFSALCGPAHPGLIVIRSLTKFYSLPGLRLGYAVLPVAMAARWQAWRDPWPVN HHHCCHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCHH ALAQHLGVAALADLDFERRTRAWLGPARSRLAAGLALLPGLTVLPGAANFLLVQSAASAV HHHHHHCHHHHHHCCHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH HLQAELLRRHRLLIRHCTSYDGLGERYFRVAVRGESENDLLTGALAEILAKTPATSRVDG HHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCC CASSPPPSTDPVHPE CCCCCCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 11677608; 12644504 [H]