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The map label for this gene is moeZ [H]

Identifier: 37522981

GI number: 37522981

Start: 3610217

End: 3611404

Strand: Reverse

Name: moeZ [H]

Synonym: gll3412

Alternate gene names: 37522981

Gene position: 3611404-3610217 (Counterclockwise)

Preceding gene: 37522982

Following gene: 37522977

Centisome position: 77.51

GC content: 62.37

Gene sequence:

>1188_bases
ATGCTCAACCCCGATACGACGACGATCGAACTCTCGAGAGACGAACTGGAGCGCTACTCCCGCCACTTGATCTTGCCGGA
GGTGGGTCTGGAGGGCCAGAAGAAGCTCAAAGCCGCCTCGGTGCTGTGTGTGGGTACCGGCGGTCTAGGGGCACCACTCA
CGATGTACCTGGCCGCCGCCGGTATCGGCCGCATCGGTCTGGTGGATTTTGACGTGGTCGATGCGAGCAACCTCCAGCGC
CAGATCATCCACGGCACCTCCTGGATCGGCAAGCCCAAAATCGATTCGGCCACCGACCGCCTCCAAGAGATCAACCCGCA
CCTGCAAATCGACCGCTGGCCGGTGCGCCTTTCGAGCGAAAACGCCCTCGACATTTGCCGCGATTACGACTTGATCATCG
ACGGCACCGACAATTTTCCGACCCGCTATCTGGTCAACGACGCTTGCGTTCTGCTGGGCAAACCGAACGTCTACGGCTCG
ATCTTCCGCTTCGAGGGCCAATCGACTGTCTTCCACTACGAGGACGGCCCCTGCTACCGCTGCCTCTACCCGGAGCCGCC
GCCGCCGGGCCTGGTGCCCAGTTGTGCCGAAGGCGGCGTCCTGGGGATCTTACCGGGGGTGATCGGTGTCATCCAGGCCA
CCGAGGCGGTCAAGATCATCCTGGGCATCGGCACCACCCTCAAGGGCCGCCTGATGCTCTACGACGCCCTCAACATGAAG
TTCCGCGAGCTGAAGCTGCGCAGGAACCCCGAGTGCCCGGTGTGCGGGGATCACCCGACGGTCACATCGCTCATCGACTA
CGAGGAATTCTGCGGCATCCCCCAGGCCCGCGCCGAAGAAGAAAAGGCCAAAGCAACCATGAAAGAAATCACCGCGACCG
CACTGAAGCAAATGCTGGACGCCGGTAAGGACGTCGTCGTCGTCGACGTGCGCAACCCCGACGAATTTGCCGCCGCCCGC
ATCCCCGGCACTACGCTGGTGCCGCTGCCGGAAATCGAGCAGGGACCGGGCATCGAGAAGGTGCGTTCTCTAATCAACGG
CTCCGAACTGGTGCTCCACTGCAGGAGCGGCATGCGTTCAGCCAAGGCCCTGCAAATTCTGCAGTCGGTCGGCATTGAAG
GCACCAACCTCAAAGGCGGCATCCACGCCTGGTCCGACGAGGTCGATCCAAGCGTGCCCAAGGTATAG

Upstream 100 bases:

>100_bases
TCAACGACGAAGACATCCGCCACTTGCAGCAGCAGGGTACGGCCGTCCAACCGACCGACGTCATCAGCATCGTGCCTTCG
ATCGCTGGAGGACTCTAGCC

Downstream 100 bases:

>100_bases
AAGATGTCATGGCCTGCAAAACCGCCATCGATTCAGGAGCGCAAGTCCGTGCTCGATGAGCTCGCCTACGAAGCTCAAGA
GCAGGACATGGGCTACGCAT

Product: hypothetical protein

Products: NA

Alternate protein names: Sulfur carrier protein CysO adenylyltransferase; Sulfur carrier protein CysO sulfurtransferase [H]

Number of amino acids: Translated: 395; Mature: 395

Protein sequence:

>395_residues
MLNPDTTTIELSRDELERYSRHLILPEVGLEGQKKLKAASVLCVGTGGLGAPLTMYLAAAGIGRIGLVDFDVVDASNLQR
QIIHGTSWIGKPKIDSATDRLQEINPHLQIDRWPVRLSSENALDICRDYDLIIDGTDNFPTRYLVNDACVLLGKPNVYGS
IFRFEGQSTVFHYEDGPCYRCLYPEPPPPGLVPSCAEGGVLGILPGVIGVIQATEAVKIILGIGTTLKGRLMLYDALNMK
FRELKLRRNPECPVCGDHPTVTSLIDYEEFCGIPQARAEEEKAKATMKEITATALKQMLDAGKDVVVVDVRNPDEFAAAR
IPGTTLVPLPEIEQGPGIEKVRSLINGSELVLHCRSGMRSAKALQILQSVGIEGTNLKGGIHAWSDEVDPSVPKV

Sequences:

>Translated_395_residues
MLNPDTTTIELSRDELERYSRHLILPEVGLEGQKKLKAASVLCVGTGGLGAPLTMYLAAAGIGRIGLVDFDVVDASNLQR
QIIHGTSWIGKPKIDSATDRLQEINPHLQIDRWPVRLSSENALDICRDYDLIIDGTDNFPTRYLVNDACVLLGKPNVYGS
IFRFEGQSTVFHYEDGPCYRCLYPEPPPPGLVPSCAEGGVLGILPGVIGVIQATEAVKIILGIGTTLKGRLMLYDALNMK
FRELKLRRNPECPVCGDHPTVTSLIDYEEFCGIPQARAEEEKAKATMKEITATALKQMLDAGKDVVVVDVRNPDEFAAAR
IPGTTLVPLPEIEQGPGIEKVRSLINGSELVLHCRSGMRSAKALQILQSVGIEGTNLKGGIHAWSDEVDPSVPKV
>Mature_395_residues
MLNPDTTTIELSRDELERYSRHLILPEVGLEGQKKLKAASVLCVGTGGLGAPLTMYLAAAGIGRIGLVDFDVVDASNLQR
QIIHGTSWIGKPKIDSATDRLQEINPHLQIDRWPVRLSSENALDICRDYDLIIDGTDNFPTRYLVNDACVLLGKPNVYGS
IFRFEGQSTVFHYEDGPCYRCLYPEPPPPGLVPSCAEGGVLGILPGVIGVIQATEAVKIILGIGTTLKGRLMLYDALNMK
FRELKLRRNPECPVCGDHPTVTSLIDYEEFCGIPQARAEEEKAKATMKEITATALKQMLDAGKDVVVVDVRNPDEFAAAR
IPGTTLVPLPEIEQGPGIEKVRSLINGSELVLHCRSGMRSAKALQILQSVGIEGTNLKGGIHAWSDEVDPSVPKV

Specific function: Catalyzes the conversion of the sulfur carrier protein CysO to CysO-thiocarboxylate. The reaction is thought to proceed in two steps:first, ATP-dependent activation of CysO as acyl- adenylate (CysO-COOAMP), followed by sulfur transfer to give CysO- thioca

COG id: COG0476

COG function: function code H; Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 rhodanese domain [H]

Homologues:

Organism=Homo sapiens, GI7657339, Length=405, Percent_Identity=42.4691358024691, Blast_Score=301, Evalue=5e-82,
Organism=Homo sapiens, GI4885649, Length=147, Percent_Identity=28.5714285714286, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI1787048, Length=248, Percent_Identity=45.5645161290323, Blast_Score=220, Evalue=1e-58,
Organism=Escherichia coli, GI87082356, Length=244, Percent_Identity=42.6229508196721, Blast_Score=171, Evalue=8e-44,
Organism=Caenorhabditis elegans, GI17540406, Length=401, Percent_Identity=39.4014962593516, Blast_Score=277, Evalue=6e-75,
Organism=Caenorhabditis elegans, GI193203301, Length=167, Percent_Identity=25.748502994012, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI71984476, Length=180, Percent_Identity=29.4444444444444, Blast_Score=71, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6321903, Length=406, Percent_Identity=38.1773399014778, Blast_Score=256, Evalue=4e-69,
Organism=Saccharomyces cerevisiae, GI6320598, Length=169, Percent_Identity=27.2189349112426, Blast_Score=69, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6325438, Length=129, Percent_Identity=27.1317829457364, Blast_Score=67, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24582879, Length=397, Percent_Identity=43.3249370277078, Blast_Score=325, Evalue=2e-89,
Organism=Drosophila melanogaster, GI24660640, Length=150, Percent_Identity=28, Blast_Score=72, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007901
- InterPro:   IPR009036
- InterPro:   IPR016040
- InterPro:   IPR001763
- InterPro:   IPR000594 [H]

Pfam domain/function: PF05237 MoeZ_MoeB; PF00581 Rhodanese; PF00899 ThiF [H]

EC number: NA

Molecular weight: Translated: 42987; Mature: 42987

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: PS50206 RHODANESE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNPDTTTIELSRDELERYSRHLILPEVGLEGQKKLKAASVLCVGTGGLGAPLTMYLAAA
CCCCCCCEEEECHHHHHHHHHEEECCCCCCCCHHHHCEEEEEEEECCCCCHHHHHHHHHH
GIGRIGLVDFDVVDASNLQRQIIHGTSWIGKPKIDSATDRLQEINPHLQIDRWPVRLSSE
CCCCEEEEEEEEECHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCEEEECCEEEECCC
NALDICRDYDLIIDGTDNFPTRYLVNDACVLLGKPNVYGSIFRFEGQSTVFHYEDGPCYR
CCHHHHCCCEEEEECCCCCCCEEEECCEEEEEECCCCCEEEEEECCCCEEEEECCCCEEE
CLYPEPPPPGLVPSCAEGGVLGILPGVIGVIQATEAVKIILGIGTTLKGRLMLYDALNMK
EECCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHEEEEEECCCCCCCCEEEEEHHCCC
FRELKLRRNPECPVCGDHPTVTSLIDYEEFCGIPQARAEEEKAKATMKEITATALKQMLD
EEEHHHCCCCCCCCCCCCCCHHHHHCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AGKDVVVVDVRNPDEFAAARIPGTTLVPLPEIEQGPGIEKVRSLINGSELVLHCRSGMRS
CCCCEEEEECCCCCHHHHHCCCCCEECCCCCCCCCCCHHHHHHHHCCCCEEEEEHHCCCH
AKALQILQSVGIEGTNLKGGIHAWSDEVDPSVPKV
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLNPDTTTIELSRDELERYSRHLILPEVGLEGQKKLKAASVLCVGTGGLGAPLTMYLAAA
CCCCCCCEEEECHHHHHHHHHEEECCCCCCCCHHHHCEEEEEEEECCCCCHHHHHHHHHH
GIGRIGLVDFDVVDASNLQRQIIHGTSWIGKPKIDSATDRLQEINPHLQIDRWPVRLSSE
CCCCEEEEEEEEECHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCEEEECCEEEECCC
NALDICRDYDLIIDGTDNFPTRYLVNDACVLLGKPNVYGSIFRFEGQSTVFHYEDGPCYR
CCHHHHCCCEEEEECCCCCCCEEEECCEEEEEECCCCCEEEEEECCCCEEEEECCCCEEE
CLYPEPPPPGLVPSCAEGGVLGILPGVIGVIQATEAVKIILGIGTTLKGRLMLYDALNMK
EECCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHEEEEEECCCCCCCCEEEEEHHCCC
FRELKLRRNPECPVCGDHPTVTSLIDYEEFCGIPQARAEEEKAKATMKEITATALKQMLD
EEEHHHCCCCCCCCCCCCCCHHHHHCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AGKDVVVVDVRNPDEFAAARIPGTTLVPLPEIEQGPGIEKVRSLINGSELVLHCRSGMRS
CCCCEEEEECCCCCHHHHHCCCCCEECCCCCCCCCCCHHHHHHHHCCCCEEEEEHHCCCH
AKALQILQSVGIEGTNLKGGIHAWSDEVDPSVPKV
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]