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The map label for this gene is moaC [H]

Identifier: 37522947

GI number: 37522947

Start: 3588663

End: 3589187

Strand: Reverse

Name: moaC [H]

Synonym: gll3378

Alternate gene names: 37522947

Gene position: 3589187-3588663 (Counterclockwise)

Preceding gene: 37522953

Following gene: 37522944

Centisome position: 77.04

GC content: 66.1

Gene sequence:

>525_bases
ATGGCCGTTAGGATGGAGGCGATTTGGCGGAGTTTTCGTTTGCAGCCGCTTTCCCACATCGATGGCACCGGCGAGGCCCG
TATGGTAGACGTCACGGCCAAGCAAGCCAGTGAGCGCGTCGCCGTCGCTGAGGCGAGGGTGTGCATGGCGGCAGGCACGC
TCGAGGCGATTTTGGCGGGCAACACCCCCAAGGGGGATGTGCTTGCCACCGCCCGCATCGCCGGGATCATGGCCGCCAAG
CGCACGGGCGATTTGATTCCGCTGTGCCACCCACTGCCCATCGGCGCGGTGCACATCGAGATCACCCCCCAGAGCGAGCC
GCCCGGATTCTGCCTGCAGGCGACCGTCAAGACCCGGGCTTCGACCGGCGTCGAGATGGAGGCGCTCACCGCCGCTGCCG
TCGCGGCCCTCACCCTCTACGACATGGCCAAGGCTCTACAAAAGGACATGACCATCGAAGGGGTGCGGCTGATGCGCAAA
TCCGGGGGCCGCTCCGGCGATTACGTGCGCGAGCCTGAACCCTAA

Upstream 100 bases:

>100_bases
TACTGCTCGGACAATCTGTAGAACACGGGCGCACTTCTCCAAAAGTGGTCACTTCTTATATTACTAAGTATTTATGCTCA
GGTGTAAGGCTGCACTAGGG

Downstream 100 bases:

>100_bases
CCGGCGGCCACCGCCTCGGTTTTGGCCCGCAGACTGGCAAGCAGCTTGTCGAAGGGGGCGGTGAACTTGGCCAGGCCGTC
GGCGAGTAGCTCGCCTGTGA

Product: molybdenum cofactor biosynthesis protein MoaC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 174; Mature: 173

Protein sequence:

>174_residues
MAVRMEAIWRSFRLQPLSHIDGTGEARMVDVTAKQASERVAVAEARVCMAAGTLEAILAGNTPKGDVLATARIAGIMAAK
RTGDLIPLCHPLPIGAVHIEITPQSEPPGFCLQATVKTRASTGVEMEALTAAAVAALTLYDMAKALQKDMTIEGVRLMRK
SGGRSGDYVREPEP

Sequences:

>Translated_174_residues
MAVRMEAIWRSFRLQPLSHIDGTGEARMVDVTAKQASERVAVAEARVCMAAGTLEAILAGNTPKGDVLATARIAGIMAAK
RTGDLIPLCHPLPIGAVHIEITPQSEPPGFCLQATVKTRASTGVEMEALTAAAVAALTLYDMAKALQKDMTIEGVRLMRK
SGGRSGDYVREPEP
>Mature_173_residues
AVRMEAIWRSFRLQPLSHIDGTGEARMVDVTAKQASERVAVAEARVCMAAGTLEAILAGNTPKGDVLATARIAGIMAAKR
TGDLIPLCHPLPIGAVHIEITPQSEPPGFCLQATVKTRASTGVEMEALTAAAVAALTLYDMAKALQKDMTIEGVRLMRKS
GGRSGDYVREPEP

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z [H]

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family [H]

Homologues:

Organism=Escherichia coli, GI1787001, Length=160, Percent_Identity=55, Blast_Score=164, Evalue=4e-42,
Organism=Caenorhabditis elegans, GI32566331, Length=149, Percent_Identity=40.9395973154362, Blast_Score=120, Evalue=3e-28,
Organism=Drosophila melanogaster, GI28574490, Length=158, Percent_Identity=50.6329113924051, Blast_Score=145, Evalue=2e-35,
Organism=Drosophila melanogaster, GI28574492, Length=147, Percent_Identity=50.3401360544218, Blast_Score=130, Evalue=4e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023045
- InterPro:   IPR023046
- InterPro:   IPR002820 [H]

Pfam domain/function: PF01967 MoaC [H]

EC number: NA

Molecular weight: Translated: 18453; Mature: 18322

Theoretical pI: Translated: 8.07; Mature: 8.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVRMEAIWRSFRLQPLSHIDGTGEARMVDVTAKQASERVAVAEARVCMAAGTLEAILAG
CCEEHHHHHHHHCCCCHHHCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHCHHHHEEEC
NTPKGDVLATARIAGIMAAKRTGDLIPLCHPLPIGAVHIEITPQSEPPGFCLQATVKTRA
CCCCCCEEHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCCCCEEEEEEEHHHC
STGVEMEALTAAAVAALTLYDMAKALQKDMTIEGVRLMRKSGGRSGDYVREPEP
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
AVRMEAIWRSFRLQPLSHIDGTGEARMVDVTAKQASERVAVAEARVCMAAGTLEAILAG
CEEHHHHHHHHCCCCHHHCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHCHHHHEEEC
NTPKGDVLATARIAGIMAAKRTGDLIPLCHPLPIGAVHIEITPQSEPPGFCLQATVKTRA
CCCCCCEEHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCCCCEEEEEEEHHHC
STGVEMEALTAAAVAALTLYDMAKALQKDMTIEGVRLMRKSGGRSGDYVREPEP
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA