Click here to switch to the map view.

The map label for this gene is thiL [H]

Identifier: 37522867

GI number: 37522867

Start: 3498648

End: 3499634

Strand: Direct

Name: thiL [H]

Synonym: glr3298

Alternate gene names: 37522867

Gene position: 3498648-3499634 (Clockwise)

Preceding gene: 37522866

Following gene: 37522868

Centisome position: 75.09

GC content: 70.31

Gene sequence:

>987_bases
GTGGATATTGCCGAACTGGGTGAGCGGGGGCTGATTGCCCGGCTCGGCCGCTTTTTTGGCCAGGCCCCGCACATCCTGGT
GCCGGGGGGCGATGATGCGGCGGTGGTTGCGCCCGGTTCGGGGGCACTGGTGGCCACCACCGATTTGCTCTTCGAAGATG
TGCACTTTGGCGACCGCACCACCGGTCCCTTCGATGTGGGCTGGCGCTCCGCTGCGGCCAACCTCTCGGATCTGGCGGCC
ATGGGTGCCGCTCCGTTCGGCATGCTCGTCGGGTTGGGGCTGAGCCCCGGTACGAGCGTCGAGTGGGTGGAAGCGTTTTA
TGAAGGGTTCACCGCCTGCAGCGCGCCGGTGGGAGCCTTGCTGCTGGGGGGAGACACCTGCCGGGCCAAAAGCCGCACCG
TGGCGGTCACTGCCCTCGGTACGGTCGATCCGCGCCGGATACTCAGACGCAACGCCGCCCGGCCGGGGGACGCGCTGGTG
GTGACAGGACATCTGGGCGCTTCGCGGGCGGGCCTCGCGGTGCTGCTCGAGGCGGAGCGCTACGCCCACCTTGGGTCGCC
GGTGCGCGAAGCGGTGGTCGCCGCCCACCGGCGACCCAAGCCACGCCTGGAGGTACCGCCGCTCGTCTTTGCGCTGAGCG
GGCGGGCCGCCGCCATGGACACCAGCGACGGCCTCACCGATGCGATTGCCCAGGTGTGTGCCCAAAGCGGCTGCGGCGCG
GTGGTGGACCTGGCGGTCCTGCCCATCGACGCGGCGACAGCCCAGGTGGCGGGAAAGCAGGCCATCGCCTGGGCGCTCGG
GGGCGGCGAGGATTACGAGCTGTTGATTGCGCTGGAGCCTGGTGCCGCGGTGCAACTGGTGGAACGGCTTGCAGCGATCG
GTATCGGCGGGGCGATCGTCGGGCGGGCGGTGGCGGGAGACCGGGTTGTGGACACCGAAGACCGGCCGCTCGCCGCTCCC
GGCTTCGAGCACTTCAATCGACCGTAA

Upstream 100 bases:

>100_bases
CGTCTTCGCCTTCGGCATCTATGGCATCGTCCAGAGTCTGTTGGGCCGCTATGCGGAAGTGCCCACCATCTCCGAGGTGG
TCTACAGCCAGCTGCGCTAG

Downstream 100 bases:

>100_bases
AATGGCGGTGTAGGCCCTGGAGTCGCCGATGCAGTCCAAAAATTACTTCCGCAAGGGTTTCGGTCTTAAAGCCGAGGTAC
AGGACGATCTCAAGGCGGAG

Product: thiamine-monophosphate kinase

Products: NA

Alternate protein names: Thiamine-phosphate kinase [H]

Number of amino acids: Translated: 328; Mature: 328

Protein sequence:

>328_residues
MDIAELGERGLIARLGRFFGQAPHILVPGGDDAAVVAPGSGALVATTDLLFEDVHFGDRTTGPFDVGWRSAAANLSDLAA
MGAAPFGMLVGLGLSPGTSVEWVEAFYEGFTACSAPVGALLLGGDTCRAKSRTVAVTALGTVDPRRILRRNAARPGDALV
VTGHLGASRAGLAVLLEAERYAHLGSPVREAVVAAHRRPKPRLEVPPLVFALSGRAAAMDTSDGLTDAIAQVCAQSGCGA
VVDLAVLPIDAATAQVAGKQAIAWALGGGEDYELLIALEPGAAVQLVERLAAIGIGGAIVGRAVAGDRVVDTEDRPLAAP
GFEHFNRP

Sequences:

>Translated_328_residues
MDIAELGERGLIARLGRFFGQAPHILVPGGDDAAVVAPGSGALVATTDLLFEDVHFGDRTTGPFDVGWRSAAANLSDLAA
MGAAPFGMLVGLGLSPGTSVEWVEAFYEGFTACSAPVGALLLGGDTCRAKSRTVAVTALGTVDPRRILRRNAARPGDALV
VTGHLGASRAGLAVLLEAERYAHLGSPVREAVVAAHRRPKPRLEVPPLVFALSGRAAAMDTSDGLTDAIAQVCAQSGCGA
VVDLAVLPIDAATAQVAGKQAIAWALGGGEDYELLIALEPGAAVQLVERLAAIGIGGAIVGRAVAGDRVVDTEDRPLAAP
GFEHFNRP
>Mature_328_residues
MDIAELGERGLIARLGRFFGQAPHILVPGGDDAAVVAPGSGALVATTDLLFEDVHFGDRTTGPFDVGWRSAAANLSDLAA
MGAAPFGMLVGLGLSPGTSVEWVEAFYEGFTACSAPVGALLLGGDTCRAKSRTVAVTALGTVDPRRILRRNAARPGDALV
VTGHLGASRAGLAVLLEAERYAHLGSPVREAVVAAHRRPKPRLEVPPLVFALSGRAAAMDTSDGLTDAIAQVCAQSGCGA
VVDLAVLPIDAATAQVAGKQAIAWALGGGEDYELLIALEPGAAVQLVERLAAIGIGGAIVGRAVAGDRVVDTEDRPLAAP
GFEHFNRP

Specific function: Thiamine biosynthesis. [C]

COG id: COG0611

COG function: function code H; Thiamine monophosphate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiamine-monophosphate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786619, Length=336, Percent_Identity=34.5238095238095, Blast_Score=135, Evalue=3e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR016188
- InterPro:   IPR006283 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: =2.7.4.16 [H]

Molecular weight: Translated: 33488; Mature: 33488

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIAELGERGLIARLGRFFGQAPHILVPGGDDAAVVAPGSGALVATTDLLFEDVHFGDRT
CCHHHHCCCHHHHHHHHHHCCCCEEEEECCCCCEEEECCCCCEEEEHHHHHHHHCCCCCC
TGPFDVGWRSAAANLSDLAAMGAAPFGMLVGLGLSPGTSVEWVEAFYEGFTACSAPVGAL
CCCCCCCHHHHHCCHHHHHHHCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCEE
LLGGDTCRAKSRTVAVTALGTVDPRRILRRNAARPGDALVVTGHLGASRAGLAVLLEAER
EECCCCCCCCCCEEEEEEECCCCHHHHHHHCCCCCCCEEEEEECCCCCCCCEEEEEECHH
YAHLGSPVREAVVAAHRRPKPRLEVPPLVFALSGRAAAMDTSDGLTDAIAQVCAQSGCGA
HHHCCCHHHHHHHHHHCCCCCCCCCCCEEEEECCCEEECCCCCCHHHHHHHHHHCCCCCC
VVDLAVLPIDAATAQVAGKQAIAWALGGGEDYELLIALEPGAAVQLVERLAAIGIGGAIV
EEEEEEECCCHHHHHHCCCCEEEEEECCCCCEEEEEEECCCHHHHHHHHHHHHCCCHHHH
GRAVAGDRVVDTEDRPLAAPGFEHFNRP
HHHHCCCCEECCCCCCCCCCCHHHCCCC
>Mature Secondary Structure
MDIAELGERGLIARLGRFFGQAPHILVPGGDDAAVVAPGSGALVATTDLLFEDVHFGDRT
CCHHHHCCCHHHHHHHHHHCCCCEEEEECCCCCEEEECCCCCEEEEHHHHHHHHCCCCCC
TGPFDVGWRSAAANLSDLAAMGAAPFGMLVGLGLSPGTSVEWVEAFYEGFTACSAPVGAL
CCCCCCCHHHHHCCHHHHHHHCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCEE
LLGGDTCRAKSRTVAVTALGTVDPRRILRRNAARPGDALVVTGHLGASRAGLAVLLEAER
EECCCCCCCCCCEEEEEEECCCCHHHHHHHCCCCCCCEEEEEECCCCCCCCEEEEEECHH
YAHLGSPVREAVVAAHRRPKPRLEVPPLVFALSGRAAAMDTSDGLTDAIAQVCAQSGCGA
HHHCCCHHHHHHHHHHCCCCCCCCCCCEEEEECCCEEECCCCCCHHHHHHHHHHCCCCCC
VVDLAVLPIDAATAQVAGKQAIAWALGGGEDYELLIALEPGAAVQLVERLAAIGIGGAIV
EEEEEEECCCHHHHHHCCCCEEEEEECCCCCEEEEEEECCCHHHHHHHHHHHHCCCHHHH
GRAVAGDRVVDTEDRPLAAPGFEHFNRP
HHHHCCCCEECCCCCCCCCCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA