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The map label for this gene is aroE [H]

Identifier: 37522847

GI number: 37522847

Start: 3482915

End: 3483772

Strand: Reverse

Name: aroE [H]

Synonym: gvip451

Alternate gene names: 37522847

Gene position: 3483772-3482915 (Counterclockwise)

Preceding gene: 37522851

Following gene: 37522844

Centisome position: 74.77

GC content: 64.34

Gene sequence:

>858_bases
ATGTCCGACTCTCCAGCTATTCGCGGCACTACCCGGCTGTTGGGCCTGTTGGGGTATCCGGTCGGCCATTCGCTGTCCCC
GGTGATGCACAACGCCGCCCTCGCCCGCCTCGGCCTTGATCTGGTCTACGTGCCCCTGCCGGTGGCCCCCGCCGATTTGC
CCCAGGCGGTGGCGGGTTTGCGGCGCGCAGGCTTCGTGGGCTTCAACGTCACCATTCCCCACAAGCAGGCGATCGTACCT
TTGCTCGACACACTCACCCCCGAGGCCAAGGGCGCCGGTGCGGTCAACACCGTGCGCGTCGAGACCGACGGAAGCCTCAC
CGGCACCAACACCGATATCGAAGGCTTCATGGGTCCGATCGAAACGGTGCCGTTTCAAGGAGCGGCCACTATCCTCGGCT
GCGGCGGCTCCGCCCTCGCAGTCGCCCTAGGCTGTGCCCAACTGGGATTCACGCGCATCCACGTTGTCGGCCGCGACCCT
GCCAAACTGGCTGCTTTCAAATCGCACCTGCACCCCGCCGCCACCGTCGAAATTGATCTTTGGGAGCAGCTGGAATCGCT
GCTGCCTGGGACGGGGTTACTCATCAACACCACGCCCGTCGGCATGATCCCGGCCACAGAAGCGAGTCCGCTCGAAGATT
TGGGGGCTCTGCCGCTAAAAGCCTGCGTCTATGACCTGATTTACCGGCCGCGCCCAACCCGGCTGTTGCAGCTGGCGGTG
GCGCGTTCGCTCCAAACCTTCGACGGTCTGGGCATGCTCGTAGGGCAGGCTGAAGCGGCCTTCTATTTCTGGACAGGCTG
TAAGCCACCCACGCAGTTGATGCTGCAGACCGCCTGCAAAGCGCTGGCGCACGATTAG

Upstream 100 bases:

>100_bases
TAGACTTAACCTGTAGCGAATATAACGGTTCCCTGTAACCACTTACTCTACATCAGTCCCGTAGCGGCGGGAGCCCCGTT
TTTCCCACAGGCGCGATACG

Downstream 100 bases:

>100_bases
ATCGCCCTTTCTGCGGCGGACAGAATCAACCGATCGAGCTGGCCGCTGTTGGCTTCGCCACGGGCGCTGAGGGCCGAGCG
CACCAGGTGGAGACCCCGGC

Product: shikimate 5-dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 285; Mature: 284

Protein sequence:

>285_residues
MSDSPAIRGTTRLLGLLGYPVGHSLSPVMHNAALARLGLDLVYVPLPVAPADLPQAVAGLRRAGFVGFNVTIPHKQAIVP
LLDTLTPEAKGAGAVNTVRVETDGSLTGTNTDIEGFMGPIETVPFQGAATILGCGGSALAVALGCAQLGFTRIHVVGRDP
AKLAAFKSHLHPAATVEIDLWEQLESLLPGTGLLINTTPVGMIPATEASPLEDLGALPLKACVYDLIYRPRPTRLLQLAV
ARSLQTFDGLGMLVGQAEAAFYFWTGCKPPTQLMLQTACKALAHD

Sequences:

>Translated_285_residues
MSDSPAIRGTTRLLGLLGYPVGHSLSPVMHNAALARLGLDLVYVPLPVAPADLPQAVAGLRRAGFVGFNVTIPHKQAIVP
LLDTLTPEAKGAGAVNTVRVETDGSLTGTNTDIEGFMGPIETVPFQGAATILGCGGSALAVALGCAQLGFTRIHVVGRDP
AKLAAFKSHLHPAATVEIDLWEQLESLLPGTGLLINTTPVGMIPATEASPLEDLGALPLKACVYDLIYRPRPTRLLQLAV
ARSLQTFDGLGMLVGQAEAAFYFWTGCKPPTQLMLQTACKALAHD
>Mature_284_residues
SDSPAIRGTTRLLGLLGYPVGHSLSPVMHNAALARLGLDLVYVPLPVAPADLPQAVAGLRRAGFVGFNVTIPHKQAIVPL
LDTLTPEAKGAGAVNTVRVETDGSLTGTNTDIEGFMGPIETVPFQGAATILGCGGSALAVALGCAQLGFTRIHVVGRDPA
KLAAFKSHLHPAATVEIDLWEQLESLLPGTGLLINTTPVGMIPATEASPLEDLGALPLKACVYDLIYRPRPTRLLQLAVA
RSLQTFDGLGMLVGQAEAAFYFWTGCKPPTQLMLQTACKALAHD

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787983, Length=276, Percent_Identity=34.4202898550725, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1789675, Length=280, Percent_Identity=30.3571428571429, Blast_Score=94, Evalue=8e-21,
Organism=Saccharomyces cerevisiae, GI6320332, Length=287, Percent_Identity=27.8745644599303, Blast_Score=80, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR011342
- InterPro:   IPR013708
- InterPro:   IPR022893
- InterPro:   IPR006151 [H]

Pfam domain/function: PF01488 Shikimate_DH; PF08501 Shikimate_dh_N [H]

EC number: =1.1.1.25 [H]

Molecular weight: Translated: 29812; Mature: 29681

Theoretical pI: Translated: 6.62; Mature: 6.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDSPAIRGTTRLLGLLGYPVGHSLSPVMHNAALARLGLDLVYVPLPVAPADLPQAVAGL
CCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHH
RRAGFVGFNVTIPHKQAIVPLLDTLTPEAKGAGAVNTVRVETDGSLTGTNTDIEGFMGPI
HHCCEEEEEEECCCHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCCCCCHHHHCCCH
ETVPFQGAATILGCGGSALAVALGCAQLGFTRIHVVGRDPAKLAAFKSHLHPAATVEIDL
HCCCCCCCEEEEECCCHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHCCCCEEEEEHH
WEQLESLLPGTGLLINTTPVGMIPATEASPLEDLGALPLKACVYDLIYRPRPTRLLQLAV
HHHHHHHCCCCCEEEECCCCCEECCCCCCCHHHHCCCHHHHHHHHHHCCCCHHHHHHHHH
ARSLQTFDGLGMLVGQAEAAFYFWTGCKPPTQLMLQTACKALAHD
HHHHHHHCCHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SDSPAIRGTTRLLGLLGYPVGHSLSPVMHNAALARLGLDLVYVPLPVAPADLPQAVAGL
CCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHH
RRAGFVGFNVTIPHKQAIVPLLDTLTPEAKGAGAVNTVRVETDGSLTGTNTDIEGFMGPI
HHCCEEEEEEECCCHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCCCCCHHHHCCCH
ETVPFQGAATILGCGGSALAVALGCAQLGFTRIHVVGRDPAKLAAFKSHLHPAATVEIDL
HCCCCCCCEEEEECCCHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHCCCCEEEEEHH
WEQLESLLPGTGLLINTTPVGMIPATEASPLEDLGALPLKACVYDLIYRPRPTRLLQLAV
HHHHHHHCCCCCEEEECCCCCEECCCCCCCHHHHCCCHHHHHHHHHHCCCCHHHHHHHHH
ARSLQTFDGLGMLVGQAEAAFYFWTGCKPPTQLMLQTACKALAHD
HHHHHHHCCHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA