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The map label for this gene is comA

Identifier: 37522842

GI number: 37522842

Start: 3476473

End: 3477897

Strand: Reverse

Name: comA

Synonym: gvip450

Alternate gene names: NA

Gene position: 3477897-3476473 (Counterclockwise)

Preceding gene: 37522844

Following gene: 37522841

Centisome position: 74.65

GC content: 62.53

Gene sequence:

>1425_bases
GTGTTTGCAGGCTGTGGTGATCGGGTGAAAAATTTTCGAATGCTCCTCTGGTGTATCGCCGGGGGACTGCTCATCGTCTC
GCTTTGGGTGCACTGGCAGCCCCAGCCGTCCCTTGGTCCGGCCGGTTCGACCGACTCCCCGGCATCGGCTTTGCCGCAGC
ACCCGCTGATCCGGGTCTACTTCAACCAGGCGCGCTCCGGGCGCTACGTCGATTATCGGGGTCTGGAGCGTCCCGGCGAC
GACCTGGAGCGGCGTATCGTCGAAGAACTCGGCCGCGCCCGCACCAGCGTCGATATCGCCATTCACGAGTTGAATCTACC
GGGAATTGCCCTGGCGATCGGCGAATGCGATCGGCGCGGGGTGGCCGTGCGCGTCATCTTGGAGCACACCTACCACCGCG
ACTTTGCATCTGTGGCTTTTGCGAATCGCCTCAAAAGCGCCGATCGCGAAGCCTACGACCGGTGGCGGCAATTCGTAGAT
GCCAATGGTGACGGCCGGGTCGATTATGGCGAGTTGCAGAAGCGCGATGCCGTCGGGATCTTGAAGCGGGCCAAGATTCC
GGTGATTGACGACACCGACGGCGGTACGCGCGGCAGCGGCATCATGCACCACAAGTTTTTGATCATCGACAACCGCCGCG
TCGTCACCGGCTCAACCAATTTCACCACCAGCGACGTCCACGGCGACCCGGCCGACCCGCGCACCCTGGGCAATGTCAAT
CATTTGATTGTGATCGAAAGCGCTCAGGTGGCCGGGCTATTTGCCGCGGAGTTCACCTGGATGTGGGGCGACGGGCCGGG
CGGCGCTCCCGACAGCCTCTTTGGGCGGCGCAAGCCTGTCCGTCCGTTGCAATCGGTGGAGGTGGGCGAGGCGCGCATCG
GTGTGCAGTTCGGCCCCGGCGAGGGCGAGGCGGGCATCAATGCCCTGATTGCCCGCCGGGTGACCAAGGCGCGCCGGTCG
CTCGATTTTGCCCTGTTCGTCTTCAGCGCCCCCGAAATTGCCAAAGCCATCCAGCGGGCCGCCGGGCAGGGAGTGCGGGT
GCGCGGTGCCCTCGACAGCGGATTTGCCTACCGCGATTACTCGATGGGATTTGATCTATGGGGGATGCGCCCGTGTGCTT
CGAAGCAATCCCCTCCCATCAAAACGGTCGGAGTGGCGCTCCTGCCGCGCGGCGACAAACTCCACCACAAATTTGCGCTT
CTCGATAACGGCACGGTCCTTACCGGATCCCACAACTGGTCGGTCGCCGCCGATCGGCGCAACGACGAAAGCTTCTTGAT
AATCGAAAGCCCCATCGTTGCTGCCCACTTCCGGCGCGAATTCGAGCGTCTTTACAGCCGTGTGCTGCTCGGCCCACCCA
AGCGCAAGCCAAAAACCTTTACTTGCACCAAGGAAAAAGCCAAACCAAATCACCACAACAGATAG

Upstream 100 bases:

>100_bases
TCTCAGGTAAGCCCGACCGCACGTCCGGCGCCGATGTCAGCCCAGTTTCCAGCATCCAAAGACGGCAGCTTCGCCGGTTG
ATTCAGACTGACGGGCGGTT

Downstream 100 bases:

>100_bases
CAGTGATAACATCATCACCAACGTTAAGATTCTGATGAATCCCATGCACCAGGGTTCTGGCAAAGTTGTTTGCACCACGT
TGGCGCTACCGGCAGATCTG

Product: hypothetical protein

Products: NA

Alternate protein names: Helix-Hairpin-Helix Motif Protein; Phospholipase D/Competence Protein ComEA; Phospholipase D Active Site Motif Domain Protein; Phospholipase D Domain-Containing Protein; Phosphoslipase; Competence Protein ComEA Helix-Hairpin-Helix Repeat Protein; Phospholipase D Domain Protein; Endonuclease

Number of amino acids: Translated: 474; Mature: 474

Protein sequence:

>474_residues
MFAGCGDRVKNFRMLLWCIAGGLLIVSLWVHWQPQPSLGPAGSTDSPASALPQHPLIRVYFNQARSGRYVDYRGLERPGD
DLERRIVEELGRARTSVDIAIHELNLPGIALAIGECDRRGVAVRVILEHTYHRDFASVAFANRLKSADREAYDRWRQFVD
ANGDGRVDYGELQKRDAVGILKRAKIPVIDDTDGGTRGSGIMHHKFLIIDNRRVVTGSTNFTTSDVHGDPADPRTLGNVN
HLIVIESAQVAGLFAAEFTWMWGDGPGGAPDSLFGRRKPVRPLQSVEVGEARIGVQFGPGEGEAGINALIARRVTKARRS
LDFALFVFSAPEIAKAIQRAAGQGVRVRGALDSGFAYRDYSMGFDLWGMRPCASKQSPPIKTVGVALLPRGDKLHHKFAL
LDNGTVLTGSHNWSVAADRRNDESFLIIESPIVAAHFRREFERLYSRVLLGPPKRKPKTFTCTKEKAKPNHHNR

Sequences:

>Translated_474_residues
MFAGCGDRVKNFRMLLWCIAGGLLIVSLWVHWQPQPSLGPAGSTDSPASALPQHPLIRVYFNQARSGRYVDYRGLERPGD
DLERRIVEELGRARTSVDIAIHELNLPGIALAIGECDRRGVAVRVILEHTYHRDFASVAFANRLKSADREAYDRWRQFVD
ANGDGRVDYGELQKRDAVGILKRAKIPVIDDTDGGTRGSGIMHHKFLIIDNRRVVTGSTNFTTSDVHGDPADPRTLGNVN
HLIVIESAQVAGLFAAEFTWMWGDGPGGAPDSLFGRRKPVRPLQSVEVGEARIGVQFGPGEGEAGINALIARRVTKARRS
LDFALFVFSAPEIAKAIQRAAGQGVRVRGALDSGFAYRDYSMGFDLWGMRPCASKQSPPIKTVGVALLPRGDKLHHKFAL
LDNGTVLTGSHNWSVAADRRNDESFLIIESPIVAAHFRREFERLYSRVLLGPPKRKPKTFTCTKEKAKPNHHNR
>Mature_474_residues
MFAGCGDRVKNFRMLLWCIAGGLLIVSLWVHWQPQPSLGPAGSTDSPASALPQHPLIRVYFNQARSGRYVDYRGLERPGD
DLERRIVEELGRARTSVDIAIHELNLPGIALAIGECDRRGVAVRVILEHTYHRDFASVAFANRLKSADREAYDRWRQFVD
ANGDGRVDYGELQKRDAVGILKRAKIPVIDDTDGGTRGSGIMHHKFLIIDNRRVVTGSTNFTTSDVHGDPADPRTLGNVN
HLIVIESAQVAGLFAAEFTWMWGDGPGGAPDSLFGRRKPVRPLQSVEVGEARIGVQFGPGEGEAGINALIARRVTKARRS
LDFALFVFSAPEIAKAIQRAAGQGVRVRGALDSGFAYRDYSMGFDLWGMRPCASKQSPPIKTVGVALLPRGDKLHHKFAL
LDNGTVLTGSHNWSVAADRRNDESFLIIESPIVAAHFRREFERLYSRVLLGPPKRKPKTFTCTKEKAKPNHHNR

Specific function: Unknown

COG id: COG1502

COG function: function code I; Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthases and related enzymes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI270265812, Length=141, Percent_Identity=30.4964539007092, Blast_Score=68, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 52420; Mature: 52420

Theoretical pI: Translated: 10.20; Mature: 10.20

Prosite motif: PS00018 EF_HAND_1 ; PS50035 PLD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFAGCGDRVKNFRMLLWCIAGGLLIVSLWVHWQPQPSLGPAGSTDSPASALPQHPLIRVY
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCHHHCCCCCEEEEE
FNQARSGRYVDYRGLERPGDDLERRIVEELGRARTSVDIAIHELNLPGIALAIGECDRRG
EECCCCCCEEECCCCCCCCHHHHHHHHHHHHHCCCEEEEEEEEECCCCEEEEECCCCCCC
VAVRVILEHTYHRDFASVAFANRLKSADREAYDRWRQFVDANGDGRVDYGELQKRDAVGI
EEEEEEEHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
LKRAKIPVIDDTDGGTRGSGIMHHKFLIIDNRRVVTGSTNFTTSDVHGDPADPRTLGNVN
HHHCCCCEEECCCCCCCCCCEEEEEEEEEECCEEEECCCCCEECCCCCCCCCCCCCCCCC
HLIVIESAQVAGLFAAEFTWMWGDGPGGAPDSLFGRRKPVRPLQSVEVGEARIGVQFGPG
EEEEEECCCEEEEEEEEEEEEECCCCCCCCHHHHCCCCCCCCHHCCCCCCEEEEEEECCC
EGEAGINALIARRVTKARRSLDFALFVFSAPEIAKAIQRAAGQGVRVRGALDSGFAYRDY
CCCHHHHHHHHHHHHHHHHCCEEEEEEECCHHHHHHHHHHCCCCEEEEEECCCCCEEEEC
SMGFDLWGMRPCASKQSPPIKTVGVALLPRGDKLHHKFALLDNGTVLTGSHNWSVAADRR
CCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCEEEEEEECCEEEECCCCCEEEECCC
NDESFLIIESPIVAAHFRREFERLYSRVLLGPPKRKPKTFTCTKEKAKPNHHNR
CCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEHHCCCCCCCCC
>Mature Secondary Structure
MFAGCGDRVKNFRMLLWCIAGGLLIVSLWVHWQPQPSLGPAGSTDSPASALPQHPLIRVY
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCHHHCCCCCEEEEE
FNQARSGRYVDYRGLERPGDDLERRIVEELGRARTSVDIAIHELNLPGIALAIGECDRRG
EECCCCCCEEECCCCCCCCHHHHHHHHHHHHHCCCEEEEEEEEECCCCEEEEECCCCCCC
VAVRVILEHTYHRDFASVAFANRLKSADREAYDRWRQFVDANGDGRVDYGELQKRDAVGI
EEEEEEEHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
LKRAKIPVIDDTDGGTRGSGIMHHKFLIIDNRRVVTGSTNFTTSDVHGDPADPRTLGNVN
HHHCCCCEEECCCCCCCCCCEEEEEEEEEECCEEEECCCCCEECCCCCCCCCCCCCCCCC
HLIVIESAQVAGLFAAEFTWMWGDGPGGAPDSLFGRRKPVRPLQSVEVGEARIGVQFGPG
EEEEEECCCEEEEEEEEEEEEECCCCCCCCHHHHCCCCCCCCHHCCCCCCEEEEEEECCC
EGEAGINALIARRVTKARRSLDFALFVFSAPEIAKAIQRAAGQGVRVRGALDSGFAYRDY
CCCHHHHHHHHHHHHHHHHCCEEEEEEECCHHHHHHHHHHCCCCEEEEEECCCCCEEEEC
SMGFDLWGMRPCASKQSPPIKTVGVALLPRGDKLHHKFALLDNGTVLTGSHNWSVAADRR
CCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCEEEEEEECCEEEECCCCCEEEECCC
NDESFLIIESPIVAAHFRREFERLYSRVLLGPPKRKPKTFTCTKEKAKPNHHNR
CCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA