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The map label for this gene is engD [H]

Identifier: 37522802

GI number: 37522802

Start: 3440202

End: 3441296

Strand: Reverse

Name: engD [H]

Synonym: gll3233

Alternate gene names: 37522802

Gene position: 3441296-3440202 (Counterclockwise)

Preceding gene: 37522816

Following gene: 37522800

Centisome position: 73.86

GC content: 62.28

Gene sequence:

>1095_bases
ATGCTCAAGACAGGCATCGTCGGTCTGCCCAACGTCGGCAAATCCACCCTTTTTAACGCCCTGGTCGAAAATGCCAAGGC
CCAGGCCGCCAATTTTCCGTTCTGCACCATCGAGCCCAACACTGGGGTGGTGAATGTACCGGACGAACGCCTGGGGATCT
TGGCCCGCATCGTCTCCACCAGCACGATCATCCCGGCGCGCATCGAGTACGTCGATATCGCCGGTCTGGTGCGCGGCGCC
AGCCAGGGCGAGGGTCTGGGCAACCAGTTTCTTTCGCACATCCGCCAGGTGGACGCGCTCGTCCACGTTGTGCGCTGCTT
CGAGAGCACCGACATCATCCACGTCGAAGGGTCTGTCGATCCGGTCCGCGACATCTCGACGATCAACCTGGAGTTGGCCC
TTTCGGATCTGGGGCAGGTCGACAAGCGCCTACAGAAAATTGCTAAGCAAAAAGGCACCAGCAAAGACCAGTACGCCGTC
GAGAGCAGTGCGCTCGAAAAGATCACCGCGGTGCTCAACGAGGGCAAGCCCGCCCGTTCCTGCGCCCTCACCGACGCCGA
AAAGGAGACTGTCGTCCCTCTAGAGTTGCTTACCTTCAAACCGGTCATCTACGCTGCGAACGTCTCTGAAGAGGAACTCG
CCACCGGCAACCGCTTCACCGAGCAGGTGGCCGCCATCGCCGCCGAGGAAAGCGCCCTGATGGTCGTCATCTCCGCCCAA
CTGGAGGCGGAACTGGCGGAACTGGAGCCCGAGGAGCGCAGCGCCTACCTCACGGACCTCGGGGTGAGCGATTCGGGGTT
GCAAAAGATGATCCGCGCCACCTACGACCTGTTGGGTCTGCAGACGTTTTTCACCGCGGGCGAAAAGGAAGTGCGCGCCT
GGACGATTACCCGCGGCACCACCGCTCCCCAGGCCGCCGGCACCATCCACACCGACTTCGAGCGCGGCTTTATTCGGGCC
GAGACCGTGGCCTACCCGGATCTGGTGACAGCGGGCTCCCAGGTGGCCGCCCGCGAAAAAGGCCAGGTGCGCTCCGAGGG
CAAGGAGTACATCGTCAAAGACGGCGACGTCATGCACTTTCGGTTCAACGTCTGA

Upstream 100 bases:

>100_bases
TTTTTTGGCTGCGTTACAGGGCGTGGCCCCGGAGCCCCCTCCTCCCCGACCGGGGACAGAACGCATTAAGATCGTTTTAC
ATTCGAGTGTCGCGCCACCC

Downstream 100 bases:

>100_bases
CGCCTCACCCCCGAATACTCACCGGCATGATCAGATACTGATAATTCCCATCGCCCACAGGCTTGAGCACCGCCGGATCG
CTCGCTCCGTTGAGGCAAAA

Product: GTP-dependent nucleic acid-binding protein EngD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 364; Mature: 364

Protein sequence:

>364_residues
MLKTGIVGLPNVGKSTLFNALVENAKAQAANFPFCTIEPNTGVVNVPDERLGILARIVSTSTIIPARIEYVDIAGLVRGA
SQGEGLGNQFLSHIRQVDALVHVVRCFESTDIIHVEGSVDPVRDISTINLELALSDLGQVDKRLQKIAKQKGTSKDQYAV
ESSALEKITAVLNEGKPARSCALTDAEKETVVPLELLTFKPVIYAANVSEEELATGNRFTEQVAAIAAEESALMVVISAQ
LEAELAELEPEERSAYLTDLGVSDSGLQKMIRATYDLLGLQTFFTAGEKEVRAWTITRGTTAPQAAGTIHTDFERGFIRA
ETVAYPDLVTAGSQVAAREKGQVRSEGKEYIVKDGDVMHFRFNV

Sequences:

>Translated_364_residues
MLKTGIVGLPNVGKSTLFNALVENAKAQAANFPFCTIEPNTGVVNVPDERLGILARIVSTSTIIPARIEYVDIAGLVRGA
SQGEGLGNQFLSHIRQVDALVHVVRCFESTDIIHVEGSVDPVRDISTINLELALSDLGQVDKRLQKIAKQKGTSKDQYAV
ESSALEKITAVLNEGKPARSCALTDAEKETVVPLELLTFKPVIYAANVSEEELATGNRFTEQVAAIAAEESALMVVISAQ
LEAELAELEPEERSAYLTDLGVSDSGLQKMIRATYDLLGLQTFFTAGEKEVRAWTITRGTTAPQAAGTIHTDFERGFIRA
ETVAYPDLVTAGSQVAAREKGQVRSEGKEYIVKDGDVMHFRFNV
>Mature_364_residues
MLKTGIVGLPNVGKSTLFNALVENAKAQAANFPFCTIEPNTGVVNVPDERLGILARIVSTSTIIPARIEYVDIAGLVRGA
SQGEGLGNQFLSHIRQVDALVHVVRCFESTDIIHVEGSVDPVRDISTINLELALSDLGQVDKRLQKIAKQKGTSKDQYAV
ESSALEKITAVLNEGKPARSCALTDAEKETVVPLELLTFKPVIYAANVSEEELATGNRFTEQVAAIAAEESALMVVISAQ
LEAELAELEPEERSAYLTDLGVSDSGLQKMIRATYDLLGLQTFFTAGEKEVRAWTITRGTTAPQAAGTIHTDFERGFIRA
ETVAYPDLVTAGSQVAAREKGQVRSEGKEYIVKDGDVMHFRFNV

Specific function: GTP-dependent nucleic acid-binding protein which may act as a translation factor [H]

COG id: COG0012

COG function: function code J; Predicted GTPase, probable translation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI58761500, Length=370, Percent_Identity=46.7567567567568, Blast_Score=319, Evalue=3e-87,
Organism=Homo sapiens, GI58761502, Length=232, Percent_Identity=39.6551724137931, Blast_Score=158, Evalue=8e-39,
Organism=Homo sapiens, GI24308117, Length=100, Percent_Identity=37, Blast_Score=69, Evalue=5e-12,
Organism=Escherichia coli, GI1787454, Length=364, Percent_Identity=54.9450549450549, Blast_Score=395, Evalue=1e-111,
Organism=Escherichia coli, GI1789574, Length=128, Percent_Identity=35.9375, Blast_Score=76, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17509631, Length=366, Percent_Identity=43.9890710382514, Blast_Score=310, Evalue=7e-85,
Organism=Saccharomyces cerevisiae, GI6319499, Length=369, Percent_Identity=42.5474254742547, Blast_Score=267, Evalue=2e-72,
Organism=Saccharomyces cerevisiae, GI6321773, Length=379, Percent_Identity=36.1477572559367, Blast_Score=221, Evalue=1e-58,
Organism=Drosophila melanogaster, GI24640873, Length=370, Percent_Identity=44.0540540540541, Blast_Score=298, Evalue=4e-81,
Organism=Drosophila melanogaster, GI24640877, Length=370, Percent_Identity=44.0540540540541, Blast_Score=298, Evalue=4e-81,
Organism=Drosophila melanogaster, GI24640875, Length=370, Percent_Identity=44.0540540540541, Blast_Score=298, Evalue=4e-81,
Organism=Drosophila melanogaster, GI24640879, Length=331, Percent_Identity=41.3897280966767, Blast_Score=243, Evalue=1e-64,
Organism=Drosophila melanogaster, GI24585318, Length=138, Percent_Identity=34.0579710144928, Blast_Score=71, Evalue=9e-13,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR004396
- InterPro:   IPR013029
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR012676
- InterPro:   IPR023192 [H]

Pfam domain/function: PF01926 MMR_HSR1; PF06071 YchF-GTPase_C [H]

EC number: NA

Molecular weight: Translated: 39363; Mature: 39363

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKTGIVGLPNVGKSTLFNALVENAKAQAANFPFCTIEPNTGVVNVPDERLGILARIVST
CCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEECCHHHHHHHHHHHHH
STIIPARIEYVDIAGLVRGASQGEGLGNQFLSHIRQVDALVHVVRCFESTDIIHVEGSVD
CCCCCCEEEEEEHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCC
PVRDISTINLELALSDLGQVDKRLQKIAKQKGTSKDQYAVESSALEKITAVLNEGKPARS
CCCCCEEEEEEEEHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCHH
CALTDAEKETVVPLELLTFKPVIYAANVSEEELATGNRFTEQVAAIAAEESALMVVISAQ
EECCCCCCCCCCCHHHHEECCEEEECCCCHHHHHCCCHHHHHHHHHHCCCCEEEEEEECH
LEAELAELEPEERSAYLTDLGVSDSGLQKMIRATYDLLGLQTFFTAGEKEVRAWTITRGT
HHHHHHHCCCHHHCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCC
TAPQAAGTIHTDFERGFIRAETVAYPDLVTAGSQVAAREKGQVRSEGKEYIVKDGDVMHF
CCCCCCCCEECHHHCCCEEEHHCCCCHHHHCCCHHHHHHCCCHHHCCCEEEEECCCEEEE
RFNV
EECC
>Mature Secondary Structure
MLKTGIVGLPNVGKSTLFNALVENAKAQAANFPFCTIEPNTGVVNVPDERLGILARIVST
CCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEECCHHHHHHHHHHHHH
STIIPARIEYVDIAGLVRGASQGEGLGNQFLSHIRQVDALVHVVRCFESTDIIHVEGSVD
CCCCCCEEEEEEHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCC
PVRDISTINLELALSDLGQVDKRLQKIAKQKGTSKDQYAVESSALEKITAVLNEGKPARS
CCCCCEEEEEEEEHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCHH
CALTDAEKETVVPLELLTFKPVIYAANVSEEELATGNRFTEQVAAIAAEESALMVVISAQ
EECCCCCCCCCCCHHHHEECCEEEECCCCHHHHHCCCHHHHHHHHHHCCCCEEEEEEECH
LEAELAELEPEERSAYLTDLGVSDSGLQKMIRATYDLLGLQTFFTAGEKEVRAWTITRGT
HHHHHHHCCCHHHCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCC
TAPQAAGTIHTDFERGFIRAETVAYPDLVTAGSQVAAREKGQVRSEGKEYIVKDGDVMHF
CCCCCCCCEECHHHCCCEEEHHCCCCHHHHCCCHHHHHHCCCHHHCCCEEEEECCCEEEE
RFNV
EECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]