Click here to switch to the map view.

The map label for this gene is yfhR [C]

Identifier: 37522777

GI number: 37522777

Start: 3417425

End: 3418309

Strand: Reverse

Name: yfhR [C]

Synonym: gll3208

Alternate gene names: 37522777

Gene position: 3418309-3417425 (Counterclockwise)

Preceding gene: 37522778

Following gene: 37522776

Centisome position: 73.37

GC content: 62.26

Gene sequence:

>885_bases
ATGGGTCGATTTGAAACAACGCTGTCCATCCCTTTGCCGCGCCCTGTTCGGATGCTACTTATCGGACTGATCGTGCTTGC
GCTGCTACTCTACGCAGGTGCGTGCGCCTGCCTCCGGCAGGTCCAGGAGCGTTTTATTTTCTTTCCTGAACGGGAAGTCA
CCGAAACTCCCGCCACCTACGGCCTGGGCTACGAAGACGTGTACCTGCCGCTGGAGAAAGATCAACTGCACGGCTGGTGG
ATCCCGGCGGCTCGCCCTGATGCGCCGGTGGTGCTCTACCTGCACGGCAACGGCATCAACGTCGGCGCCAACGCCGAACA
CGCCCACCGCCTGCAGTACCGGTTGGGTTTTACCGTCTTTTTGTTTGACTACCGCGGCTACGGCAAAAGCAGCGGCCCGT
TTCCTTCAGAAAACCGGGTGTACGCCGACGCGGAGCGCGCCTGGCAGTACCTGGTGGGCGAGCGGAAAATCGACCCCCGG
CGCATTTTGCTCTACGGCCACTCGCTGGGTGGAGCGGTCGCCGTCGAAATGGCCGTGCGCCACCCGGAGGTGGCGGGTGC
GGTGGTCGAAAGCTCCTTCACCTCGATTCTGGAGATGACCGCTGCCCAGCGGTGGACGCGCTTTTTTCCCGTCGAATGGT
TATTGCACCAGCGCTTCGACTCGATTGCCAAGATGAGCCGTCTGCAGGTGCCGGTGCTTTTTATCCATGGCCGCCGCGAC
CGTGTGATCTCCCATACGATGAGCGAGCGCAACTATGCCGCCGCTCCCCAACCCAAGCGCCTGTTGCTGGTTGCAGGCGG
GGATCACGCCACCAATGCCGTCGAGGGAGGCAGCCTCTACCTGGAGGGATTTCGCACCTTCGCCCACGCAGCACTGTCGC
GGTGA

Upstream 100 bases:

>100_bases
GATGCATCCATCGCGCCCCCAGCGAGCGTACCGGTAGTAAGCGACAGCGAATTTGCCGTGCTGCACCGACGGCTTTGCAC
TTTGCTCGGACCTCCTGGCG

Downstream 100 bases:

>100_bases
ATCGTTGTACAACGACCAGACCCCTTGGATTGTCCCCACACGTAACGGACAGCCTGCGTGCGTCAAGGGTCTTGCGAAAG
AAACTCGATTGATGTATGGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 294; Mature: 293

Protein sequence:

>294_residues
MGRFETTLSIPLPRPVRMLLIGLIVLALLLYAGACACLRQVQERFIFFPEREVTETPATYGLGYEDVYLPLEKDQLHGWW
IPAARPDAPVVLYLHGNGINVGANAEHAHRLQYRLGFTVFLFDYRGYGKSSGPFPSENRVYADAERAWQYLVGERKIDPR
RILLYGHSLGGAVAVEMAVRHPEVAGAVVESSFTSILEMTAAQRWTRFFPVEWLLHQRFDSIAKMSRLQVPVLFIHGRRD
RVISHTMSERNYAAAPQPKRLLLVAGGDHATNAVEGGSLYLEGFRTFAHAALSR

Sequences:

>Translated_294_residues
MGRFETTLSIPLPRPVRMLLIGLIVLALLLYAGACACLRQVQERFIFFPEREVTETPATYGLGYEDVYLPLEKDQLHGWW
IPAARPDAPVVLYLHGNGINVGANAEHAHRLQYRLGFTVFLFDYRGYGKSSGPFPSENRVYADAERAWQYLVGERKIDPR
RILLYGHSLGGAVAVEMAVRHPEVAGAVVESSFTSILEMTAAQRWTRFFPVEWLLHQRFDSIAKMSRLQVPVLFIHGRRD
RVISHTMSERNYAAAPQPKRLLLVAGGDHATNAVEGGSLYLEGFRTFAHAALSR
>Mature_293_residues
GRFETTLSIPLPRPVRMLLIGLIVLALLLYAGACACLRQVQERFIFFPEREVTETPATYGLGYEDVYLPLEKDQLHGWWI
PAARPDAPVVLYLHGNGINVGANAEHAHRLQYRLGFTVFLFDYRGYGKSSGPFPSENRVYADAERAWQYLVGERKIDPRR
ILLYGHSLGGAVAVEMAVRHPEVAGAVVESSFTSILEMTAAQRWTRFFPVEWLLHQRFDSIAKMSRLQVPVLFIHGRRDR
VISHTMSERNYAAAPQPKRLLLVAGGDHATNAVEGGSLYLEGFRTFAHAALSR

Specific function: Unknown

COG id: COG1073

COG function: function code R; Hydrolases of the alpha/beta superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To S.pombe bem46 and yeast YNL320w [H]

Homologues:

Organism=Homo sapiens, GI49355781, Length=261, Percent_Identity=31.0344827586207, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI194306564, Length=214, Percent_Identity=36.4485981308411, Blast_Score=108, Evalue=6e-24,
Organism=Homo sapiens, GI194306562, Length=200, Percent_Identity=37, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI151301175, Length=199, Percent_Identity=35.1758793969849, Blast_Score=105, Evalue=3e-23,
Organism=Homo sapiens, GI71051602, Length=210, Percent_Identity=31.9047619047619, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI71051600, Length=212, Percent_Identity=32.5471698113208, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI109689718, Length=199, Percent_Identity=29.1457286432161, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI24308097, Length=199, Percent_Identity=29.1457286432161, Blast_Score=79, Evalue=7e-15,
Organism=Escherichia coli, GI226510965, Length=297, Percent_Identity=27.9461279461279, Blast_Score=106, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI71988362, Length=198, Percent_Identity=33.8383838383838, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI71997133, Length=144, Percent_Identity=29.1666666666667, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI71985392, Length=206, Percent_Identity=28.1553398058252, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17532877, Length=187, Percent_Identity=28.8770053475936, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6324009, Length=285, Percent_Identity=27.3684210526316, Blast_Score=86, Evalue=6e-18,
Organism=Drosophila melanogaster, GI281362521, Length=206, Percent_Identity=33.9805825242718, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI281362519, Length=206, Percent_Identity=33.9805825242718, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI28571878, Length=206, Percent_Identity=33.9805825242718, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI17137566, Length=268, Percent_Identity=29.8507462686567, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24655467, Length=187, Percent_Identity=29.4117647058824, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24655464, Length=187, Percent_Identity=29.4117647058824, Blast_Score=75, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002925 [H]

Pfam domain/function: PF01738 DLH [H]

EC number: NA

Molecular weight: Translated: 33107; Mature: 32975

Theoretical pI: Translated: 9.19; Mature: 9.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRFETTLSIPLPRPVRMLLIGLIVLALLLYAGACACLRQVQERFIFFPEREVTETPATY
CCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCHH
GLGYEDVYLPLEKDQLHGWWIPAARPDAPVVLYLHGNGINVGANAEHAHRLQYRLGFTVF
CCCCCCEEEECCCCCCCEEECCCCCCCCCEEEEEECCCEEECCCCHHHHHHHHEECEEEE
LFDYRGYGKSSGPFPSENRVYADAERAWQYLVGERKIDPRRILLYGHSLGGAVAVEMAVR
EEEECCCCCCCCCCCCCCCEEECHHHHHHHHHCCCCCCCEEEEEEECCCCCCEEEHHHHC
HPEVAGAVVESSFTSILEMTAAQRWTRFFPVEWLLHQRFDSIAKMSRLQVPVLFIHGRRD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCC
RVISHTMSERNYAAAPQPKRLLLVAGGDHATNAVEGGSLYLEGFRTFAHAALSR
HHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCCCCCCEEHHHHHHHHHHHHCC
>Mature Secondary Structure 
GRFETTLSIPLPRPVRMLLIGLIVLALLLYAGACACLRQVQERFIFFPEREVTETPATY
CCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCHH
GLGYEDVYLPLEKDQLHGWWIPAARPDAPVVLYLHGNGINVGANAEHAHRLQYRLGFTVF
CCCCCCEEEECCCCCCCEEECCCCCCCCCEEEEEECCCEEECCCCHHHHHHHHEECEEEE
LFDYRGYGKSSGPFPSENRVYADAERAWQYLVGERKIDPRRILLYGHSLGGAVAVEMAVR
EEEECCCCCCCCCCCCCCCEEECHHHHHHHHHCCCCCCCEEEEEEECCCCCCEEEHHHHC
HPEVAGAVVESSFTSILEMTAAQRWTRFFPVEWLLHQRFDSIAKMSRLQVPVLFIHGRRD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCC
RVISHTMSERNYAAAPQPKRLLLVAGGDHATNAVEGGSLYLEGFRTFAHAALSR
HHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCCCCCCEEHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]