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The map label for this gene is rnd [H]

Identifier: 37522692

GI number: 37522692

Start: 3325283

End: 3325909

Strand: Reverse

Name: rnd [H]

Synonym: gll3123

Alternate gene names: 37522692

Gene position: 3325909-3325283 (Counterclockwise)

Preceding gene: 37522695

Following gene: 37522691

Centisome position: 71.39

GC content: 62.2

Gene sequence:

>627_bases
GTGAGCGAGCAGGCACAGATTTTTACCGACGACCTCTCGCCGGAGGTGGCCGGTACGTACTTGCAAAGTGGGCTTCTGGC
GGTAGACTCCGAGGCGATGGGGCTGTTGCCCCACCGCGATCGGCTGTGCCTGGTGCAACTGTGCGACGAGGCGGGTCTGG
TGAGTCTGGTGCGCCTGAGTGCCGGTCTGACCCAGGCTTCGCAGTTGCAAAAAGTGCTCGAAGCGCCCGCGGTGATCAAG
CTGTTTCATTACGCCCGCTTCGATGTCGCCATGCTGCGCCACCACCTGGGTATCCGCGTGCAGCCTATCGTCTGCACCAA
GGTGGCGAGCAAGCTGGCGCGCACCTACAGCCCCAGACACGGCCTGAAGGATCTGGTTCTGGAGACGGTGGGAGTGGAAC
TGGACAAATCCGCCCAGAGTTCGGACTGGGGGGCGGTGCTGGAATTGTCCGAGGAACAGTTGCGCTACGCCGCCAACGAC
GTGCGCTATTTGATCCCCGCCTGGCGCAAGCTGGAGACGATGCTTAGACGCGAGGGGCGCTTCGAGCTTGCCCGGCGCTG
TTTCGCGCACCTCGAGACCCAGGTGGATTTGGATCTTCTGGGTTACAGCAGCGTCTTCGAGCATTAA

Upstream 100 bases:

>100_bases
ACTCGTTAAGGGCTCGCATGTAATAAAGGTTAACATTTCGGCGGGACTTTCTCTACTGCCTGGGGAACAGATACAGTTGA
GCGACGGCCGGGGAGACGAT

Downstream 100 bases:

>100_bases
CAAAGTGCTCCCCAGGTTAGATGGCGACGGAGACAGTCTCTGTAATCTAATGGGGGTGCCCGCTTCTTCACGGGGGTGGC
GCACGTATGTGTATTAGTGA

Product: ribonuclease D

Products: NA

Alternate protein names: RNase D [H]

Number of amino acids: Translated: 208; Mature: 207

Protein sequence:

>208_residues
MSEQAQIFTDDLSPEVAGTYLQSGLLAVDSEAMGLLPHRDRLCLVQLCDEAGLVSLVRLSAGLTQASQLQKVLEAPAVIK
LFHYARFDVAMLRHHLGIRVQPIVCTKVASKLARTYSPRHGLKDLVLETVGVELDKSAQSSDWGAVLELSEEQLRYAAND
VRYLIPAWRKLETMLRREGRFELARRCFAHLETQVDLDLLGYSSVFEH

Sequences:

>Translated_208_residues
MSEQAQIFTDDLSPEVAGTYLQSGLLAVDSEAMGLLPHRDRLCLVQLCDEAGLVSLVRLSAGLTQASQLQKVLEAPAVIK
LFHYARFDVAMLRHHLGIRVQPIVCTKVASKLARTYSPRHGLKDLVLETVGVELDKSAQSSDWGAVLELSEEQLRYAAND
VRYLIPAWRKLETMLRREGRFELARRCFAHLETQVDLDLLGYSSVFEH
>Mature_207_residues
SEQAQIFTDDLSPEVAGTYLQSGLLAVDSEAMGLLPHRDRLCLVQLCDEAGLVSLVRLSAGLTQASQLQKVLEAPAVIKL
FHYARFDVAMLRHHLGIRVQPIVCTKVASKLARTYSPRHGLKDLVLETVGVELDKSAQSSDWGAVLELSEEQLRYAANDV
RYLIPAWRKLETMLRREGRFELARRCFAHLETQVDLDLLGYSSVFEH

Specific function: Cleaves multimeric tRNA precursor at the spacer region. Contribute to the 3' maturation of several stable RNAs [H]

COG id: COG0349

COG function: function code J; Ribonuclease D

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HRDC domain [H]

Homologues:

Organism=Escherichia coli, GI1788105, Length=166, Percent_Identity=33.1325301204819, Blast_Score=67, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002562
- InterPro:   IPR002121
- InterPro:   IPR010997
- InterPro:   IPR006292
- InterPro:   IPR012337 [H]

Pfam domain/function: PF01612 3_5_exonuc; PF00570 HRDC [H]

EC number: =3.1.13.5 [H]

Molecular weight: Translated: 23332; Mature: 23201

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEQAQIFTDDLSPEVAGTYLQSGLLAVDSEAMGLLPHRDRLCLVQLCDEAGLVSLVRLS
CCCCCCEECCCCCHHHHHHHHHCCCCEECCCHHCCCCCCCCHHHHHHHCCCHHHHHHHHH
AGLTQASQLQKVLEAPAVIKLFHYARFDVAMLRHHLGIRVQPIVCTKVASKLARTYSPRH
HCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCEECHHHHHHHHHHHHHHCCCCC
GLKDLVLETVGVELDKSAQSSDWGAVLELSEEQLRYAANDVRYLIPAWRKLETMLRREGR
CHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
FELARRCFAHLETQVDLDLLGYSSVFEH
HHHHHHHHHHHHHHCCHHHHCHHHHHCC
>Mature Secondary Structure 
SEQAQIFTDDLSPEVAGTYLQSGLLAVDSEAMGLLPHRDRLCLVQLCDEAGLVSLVRLS
CCCCCEECCCCCHHHHHHHHHCCCCEECCCHHCCCCCCCCHHHHHHHCCCHHHHHHHHH
AGLTQASQLQKVLEAPAVIKLFHYARFDVAMLRHHLGIRVQPIVCTKVASKLARTYSPRH
HCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCEECHHHHHHHHHHHHHHCCCCC
GLKDLVLETVGVELDKSAQSSDWGAVLELSEEQLRYAANDVRYLIPAWRKLETMLRREGR
CHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
FELARRCFAHLETQVDLDLLGYSSVFEH
HHHHHHHHHHHHHHCCHHHHCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3041371; 9097040; 9278503; 8107670 [H]