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The map label for this gene is ybdL [H]

Identifier: 37522685

GI number: 37522685

Start: 3317666

End: 3318844

Strand: Reverse

Name: ybdL [H]

Synonym: gll3116

Alternate gene names: 37522685

Gene position: 3318844-3317666 (Counterclockwise)

Preceding gene: 37522686

Following gene: 37522684

Centisome position: 71.23

GC content: 65.22

Gene sequence:

>1179_bases
GTGGTTCCACCTGTCAAGCATCGTCTGTCGGAGCGCGCCCTCGCGGTTGTTCCCTCGCTGATTCGCGACGCCTCGCGCTA
CTGCGACGAACTCGGGGCGCTGAATTTGGCCCAGGGATTGCCGGATTTTGCGGCTCCCGCCTTTTTGAAGGAGGCGGCCC
AGCGGGCGATCGCCGCCGACCGCAACCAGTACTGTGACCCATGGGGACTGGCGCAGTTGCGCGAGGCCATCGCCGCCAAG
TGCACCAGGGACAACGCTCTGGCAGTCGATCCGGCCACGCAGGTGACGGTCTGTTGCGGAGCGACCGAGGGGATCAATCT
GGCGCTGATGGCATTGCTCGACCCGGGCGACGAAGTCGTGGTCTTCTCGCCTTTTTACGAGAACTACCGGCCGAATCTGG
CCACAGTCGAGGCAAAGCCCCGCTACGTGCCGCTCAGTGCCCCGGACTGGCGTGTCGATGAGGCGGTGCTCGAACGGGCC
TTTGCCGGTACCGCGCCCCGGGCAGTGATTGTCAACAACCCCGCCAATCCGACCGGCAAAGTCTGGTCGCGTCAGGAACT
GGAACTGGTGGCCCGCTACTGCGAGCGCCATGACGCCTACGCGATCACCGACGAGATTTACGAGTACATCCTCTACGACG
GGGCGGAGCATATCTCGCTGGCCTCGCTCGCGGGGATGGCCGAGCGCACGGTGACAGTCAGCGGGCTGTCGAAGACTTTT
TGTGTGACCGGCTGGCGACTGGGTTATGTGATCGCCTCAGAACCCCTGACCGCCGCCATCCGCAGGCTGCACGACTTTTT
GACCATCTGCGCTCCGGCACCGATGCAGCATGCCGCAGTCGCTGCCCTCGAAGCGCCTGCCGACTACTACGCCGATTTGC
GCCGCCTCTACCAGGCCAAGCGCGACCGGTTGGTGACGGCGCTGTACCGCAGCGGGTTTGAGCCGGTACGACCGGCTGGG
GCTTATTATGTCTGGACCGATGCCGGGGTGCTCGGGGCCAAAAACGCCCTGGCGGCGGCCGGACGCCTCGCCGTCGAAGC
GGGGATCGCGGCGGTGCCCGGGGATTGTTTTTTGCCGCCGGGTCATCCCAACTGCAATTTGCGCTTTTGCTATGCCAAGA
GCGACGAGACCCTGGCCGCCGCCGTCGAACGGCTCGATCGCTGGAGCGGCCATGGCTGA

Upstream 100 bases:

>100_bases
ATTGCTCGATGTACGGCTTTGCGATCCCCTGGCCGAGTTGCTGGGCCGCGAGGAATGGGCCAACGACTAGAATGCCTACA
GTCGAGATTGGGCATTATTC

Downstream 100 bases:

>100_bases
GCGGCGGGTGCGCTATACCAAGTCCAACCTGCCCAGCAAGATCTGTGCGGTCTGCGGTTTGCCTTTTGAATGGCGGCGCA
AGTGGGCCGACTGTTGGGAC

Product: aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 392; Mature: 392

Protein sequence:

>392_residues
MVPPVKHRLSERALAVVPSLIRDASRYCDELGALNLAQGLPDFAAPAFLKEAAQRAIAADRNQYCDPWGLAQLREAIAAK
CTRDNALAVDPATQVTVCCGATEGINLALMALLDPGDEVVVFSPFYENYRPNLATVEAKPRYVPLSAPDWRVDEAVLERA
FAGTAPRAVIVNNPANPTGKVWSRQELELVARYCERHDAYAITDEIYEYILYDGAEHISLASLAGMAERTVTVSGLSKTF
CVTGWRLGYVIASEPLTAAIRRLHDFLTICAPAPMQHAAVAALEAPADYYADLRRLYQAKRDRLVTALYRSGFEPVRPAG
AYYVWTDAGVLGAKNALAAAGRLAVEAGIAAVPGDCFLPPGHPNCNLRFCYAKSDETLAAAVERLDRWSGHG

Sequences:

>Translated_392_residues
MVPPVKHRLSERALAVVPSLIRDASRYCDELGALNLAQGLPDFAAPAFLKEAAQRAIAADRNQYCDPWGLAQLREAIAAK
CTRDNALAVDPATQVTVCCGATEGINLALMALLDPGDEVVVFSPFYENYRPNLATVEAKPRYVPLSAPDWRVDEAVLERA
FAGTAPRAVIVNNPANPTGKVWSRQELELVARYCERHDAYAITDEIYEYILYDGAEHISLASLAGMAERTVTVSGLSKTF
CVTGWRLGYVIASEPLTAAIRRLHDFLTICAPAPMQHAAVAALEAPADYYADLRRLYQAKRDRLVTALYRSGFEPVRPAG
AYYVWTDAGVLGAKNALAAAGRLAVEAGIAAVPGDCFLPPGHPNCNLRFCYAKSDETLAAAVERLDRWSGHG
>Mature_392_residues
MVPPVKHRLSERALAVVPSLIRDASRYCDELGALNLAQGLPDFAAPAFLKEAAQRAIAADRNQYCDPWGLAQLREAIAAK
CTRDNALAVDPATQVTVCCGATEGINLALMALLDPGDEVVVFSPFYENYRPNLATVEAKPRYVPLSAPDWRVDEAVLERA
FAGTAPRAVIVNNPANPTGKVWSRQELELVARYCERHDAYAITDEIYEYILYDGAEHISLASLAGMAERTVTVSGLSKTF
CVTGWRLGYVIASEPLTAAIRRLHDFLTICAPAPMQHAAVAALEAPADYYADLRRLYQAKRDRLVTALYRSGFEPVRPAG
AYYVWTDAGVLGAKNALAAAGRLAVEAGIAAVPGDCFLPPGHPNCNLRFCYAKSDETLAAAVERLDRWSGHG

Specific function: Shows aminotransferase activity with methionine and histidine as substrates, and to a lesser extent also with phenylalanine [H]

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=398, Percent_Identity=32.1608040201005, Blast_Score=230, Evalue=1e-60,
Organism=Homo sapiens, GI169881279, Length=398, Percent_Identity=32.1608040201005, Blast_Score=230, Evalue=1e-60,
Organism=Homo sapiens, GI56713254, Length=395, Percent_Identity=31.3924050632911, Blast_Score=217, Evalue=2e-56,
Organism=Homo sapiens, GI56713256, Length=395, Percent_Identity=31.3924050632911, Blast_Score=216, Evalue=2e-56,
Organism=Homo sapiens, GI169881281, Length=398, Percent_Identity=28.391959798995, Blast_Score=186, Evalue=3e-47,
Organism=Homo sapiens, GI4507369, Length=326, Percent_Identity=26.3803680981595, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI149944424, Length=222, Percent_Identity=28.8288288288288, Blast_Score=77, Evalue=3e-14,
Organism=Escherichia coli, GI1786816, Length=367, Percent_Identity=34.8773841961853, Blast_Score=224, Evalue=7e-60,
Organism=Escherichia coli, GI1788722, Length=356, Percent_Identity=28.9325842696629, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1788627, Length=280, Percent_Identity=32.5, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1787909, Length=334, Percent_Identity=26.3473053892216, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787710, Length=304, Percent_Identity=28.2894736842105, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1788332, Length=224, Percent_Identity=29.9107142857143, Blast_Score=67, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71994476, Length=392, Percent_Identity=30.1020408163265, Blast_Score=174, Evalue=7e-44,
Organism=Caenorhabditis elegans, GI71994472, Length=392, Percent_Identity=30.1020408163265, Blast_Score=174, Evalue=8e-44,
Organism=Caenorhabditis elegans, GI17567369, Length=388, Percent_Identity=26.0309278350515, Blast_Score=146, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI17567663, Length=301, Percent_Identity=26.2458471760797, Blast_Score=109, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6322401, Length=384, Percent_Identity=30.46875, Blast_Score=169, Evalue=5e-43,
Organism=Drosophila melanogaster, GI28573069, Length=419, Percent_Identity=30.0715990453461, Blast_Score=217, Evalue=1e-56,
Organism=Drosophila melanogaster, GI24646114, Length=419, Percent_Identity=30.0715990453461, Blast_Score=217, Evalue=1e-56,
Organism=Drosophila melanogaster, GI28573067, Length=419, Percent_Identity=30.0715990453461, Blast_Score=217, Evalue=1e-56,
Organism=Drosophila melanogaster, GI28573065, Length=419, Percent_Identity=30.0715990453461, Blast_Score=217, Evalue=1e-56,
Organism=Drosophila melanogaster, GI18859735, Length=356, Percent_Identity=26.4044943820225, Blast_Score=111, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.- [C]

Molecular weight: Translated: 42550; Mature: 42550

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVPPVKHRLSERALAVVPSLIRDASRYCDELGALNLAQGLPDFAAPAFLKEAAQRAIAAD
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCHHHHHHHHHHHHHHHHHC
RNQYCDPWGLAQLREAIAAKCTRDNALAVDPATQVTVCCGATEGINLALMALLDPGDEVV
CCCCCCCCCHHHHHHHHHHHHCCCCCEEECCCCEEEEEECCCCCCCEEEEEEECCCCCEE
VFSPFYENYRPNLATVEAKPRYVPLSAPDWRVDEAVLERAFAGTAPRAVIVNNPANPTGK
EECCHHHCCCCCEEEEECCCCEECCCCCCCCHHHHHHHHHHCCCCCCEEEECCCCCCCCC
VWSRQELELVARYCERHDAYAITDEIYEYILYDGAEHISLASLAGMAERTVTVSGLSKTF
CCCHHHHHHHHHHHHHCCCEEHHHHHHHHHHHCCHHHHHHHHHHHHHHHEEEECCCCCHH
CVTGWRLGYVIASEPLTAAIRRLHDFLTICAPAPMQHAAVAALEAPADYYADLRRLYQAK
EEECEEEEEEEECCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHH
RDRLVTALYRSGFEPVRPAGAYYVWTDAGVLGAKNALAAAGRLAVEAGIAAVPGDCFLPP
HHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCEECCCCCCCCC
GHPNCNLRFCYAKSDETLAAAVERLDRWSGHG
CCCCCCEEEEEECCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MVPPVKHRLSERALAVVPSLIRDASRYCDELGALNLAQGLPDFAAPAFLKEAAQRAIAAD
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCHHHHHHHHHHHHHHHHHC
RNQYCDPWGLAQLREAIAAKCTRDNALAVDPATQVTVCCGATEGINLALMALLDPGDEVV
CCCCCCCCCHHHHHHHHHHHHCCCCCEEECCCCEEEEEECCCCCCCEEEEEEECCCCCEE
VFSPFYENYRPNLATVEAKPRYVPLSAPDWRVDEAVLERAFAGTAPRAVIVNNPANPTGK
EECCHHHCCCCCEEEEECCCCEECCCCCCCCHHHHHHHHHHCCCCCCEEEECCCCCCCCC
VWSRQELELVARYCERHDAYAITDEIYEYILYDGAEHISLASLAGMAERTVTVSGLSKTF
CCCHHHHHHHHHHHHHCCCEEHHHHHHHHHHHCCHHHHHHHHHHHHHHHEEEECCCCCHH
CVTGWRLGYVIASEPLTAAIRRLHDFLTICAPAPMQHAAVAALEAPADYYADLRRLYQAK
EEECEEEEEEEECCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHH
RDRLVTALYRSGFEPVRPAGAYYVWTDAGVLGAKNALAAAGRLAVEAGIAAVPGDCFLPP
HHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCEECCCCCCCCC
GHPNCNLRFCYAKSDETLAAAVERLDRWSGHG
CCCCCCEEEEEECCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]