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The map label for this gene is sugE [H]

Identifier: 37522556

GI number: 37522556

Start: 3186995

End: 3187315

Strand: Reverse

Name: sugE [H]

Synonym: gll2987

Alternate gene names: 37522556

Gene position: 3187315-3186995 (Counterclockwise)

Preceding gene: 37522558

Following gene: 37522554

Centisome position: 68.41

GC content: 60.44

Gene sequence:

>321_bases
ATGTCTTGGGTCGCCCTGATCTCTGCCGGATTGCTCGAAATCGGTTGGGCCGTCGGTCTGAAATACTCGGAAGGTTTTAC
TCGTTTTTTGCCCTCGGTGCTGACGGGCCTTTCGATGGTCCTGAGCCTCGGACTGCTGGGCTACGCGCTTAAAAGCCTGC
CCATCGGGACCGCTTACGCCGTCTGGACCGGTGTCGGCACCGTCGGTACAGCCCTCTTGGGGATATGGTTGTTCGGCGAA
TCGGCAAGCGCCCTGCGCCTTGCCTGCATCGGCCTCATCGTCGCGGGCATCGTCGGATTGAAATGGGTGGCCCCACACTA
A

Upstream 100 bases:

>100_bases
GCCGATGGCCCGCCCGATTTGCCACAATCAAAACGGTGGGGACGACCCCACCCTTCGCAAAGTTTCGCGGGGACGACCCC
GCACCCACAGGAGGTGCGCC

Downstream 100 bases:

>100_bases
GGAAGGCTACAGGTCTGCAACTGCTTTGGCGACCGTCAGAAAATGACCCAGGATGGGCGAAGTGTTGTCCTGGTGCCAGG
CGGCGGCCAGGACCAGCCTC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 106; Mature: 105

Protein sequence:

>106_residues
MSWVALISAGLLEIGWAVGLKYSEGFTRFLPSVLTGLSMVLSLGLLGYALKSLPIGTAYAVWTGVGTVGTALLGIWLFGE
SASALRLACIGLIVAGIVGLKWVAPH

Sequences:

>Translated_106_residues
MSWVALISAGLLEIGWAVGLKYSEGFTRFLPSVLTGLSMVLSLGLLGYALKSLPIGTAYAVWTGVGTVGTALLGIWLFGE
SASALRLACIGLIVAGIVGLKWVAPH
>Mature_105_residues
SWVALISAGLLEIGWAVGLKYSEGFTRFLPSVLTGLSMVLSLGLLGYALKSLPIGTAYAVWTGVGTVGTALLGIWLFGES
ASALRLACIGLIVAGIVGLKWVAPH

Specific function: Quaternary ammonium compound efflux pump. Confers resistance to cetylpyridinium, cetyldimethylethyl ammonium and cetrimide cations [H]

COG id: COG2076

COG function: function code P; Membrane transporters of cations and cationic drugs

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the small multidrug resistance (SMR) protein family. SugE (TC 2.A.7.1.4) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082378, Length=101, Percent_Identity=62.3762376237624, Blast_Score=126, Evalue=3e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000390 [H]

Pfam domain/function: PF00893 Multi_Drug_Res [H]

EC number: NA

Molecular weight: Translated: 10961; Mature: 10830

Theoretical pI: Translated: 9.17; Mature: 9.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSWVALISAGLLEIGWAVGLKYSEGFTRFLPSVLTGLSMVLSLGLLGYALKSLPIGTAYA
CHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
VWTGVGTVGTALLGIWLFGESASALRLACIGLIVAGIVGLKWVAPH
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SWVALISAGLLEIGWAVGLKYSEGFTRFLPSVLTGLSMVLSLGLLGYALKSLPIGTAYA
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
VWTGVGTVGTALLGIWLFGESASALRLACIGLIVAGIVGLKWVAPH
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]