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The map label for this gene is mltA [H]

Identifier: 37522471

GI number: 37522471

Start: 3097703

End: 3098767

Strand: Reverse

Name: mltA [H]

Synonym: gll2902

Alternate gene names: 37522471

Gene position: 3098767-3097703 (Counterclockwise)

Preceding gene: 37522472

Following gene: 37522470

Centisome position: 66.51

GC content: 65.35

Gene sequence:

>1065_bases
GTGGCGCGCTCTGAGGAGCCGCTTTTGGTGGGTGCGAGCTTCGAGGAGGTGGATCTTGCGGGTGGCTGGCACGACCGCTG
GACGCTCATCAAGAGTGTGGATACCAGCCTGCGGTATCTCTCTACCCCGGCAGCTTCGCGCGCCTATCCACGCCGGGGGA
TCACCCGCGAACGGCTTGCTGCGAGTCTCAGGCGCTTTCGGGCCATCTTGAAGACTTCGCCTAGCGCAGAAGCATTCAGC
GTGCGGGTGGGGCGCGAATTTGACCTCTATCGGGTCAATCCCGAGCCCGACAGCCCCGAGGTGCTCATCACCGGCTACTT
CGCGCCGGTCTACCGGGCGAGCCGCAAACCTACCGCAACCTACCGCTACCCGCTCTACAAAACCCCCGGCGACCTTGTCA
CCGACGGCGTGCGCGGTCTCGGTCAGCGCACCGCCGCCGGGGTGCGGCCCTACCCCACCCGCGCGCAGATCGAAAAGCAG
AATTTGCTCGCAGGCCGCGAACTGATCTGGCTGGCCGATCCGCTCGAACGCTTTTTGGTGCACGTCCAGGGCTCGGCGAA
GCTGGTGCTGACCGACGGTGCGACCCGCTCGGTGGGCTTTGCCGCCAAGACCGATAGGCCCTACCAGAGCATCGGCAAGG
CGCTGGTGGCCGACGGCAAAATCCGCGAGGAAGACCTGACGCTGCAGGCGGTCAAAGCTTACTTTCGCGCCCACCCGGAG
GAGCTTGAATCCTACTTGCACAAAAACGAGTCCTACGTTTTTTTCCGTTGGACCGACGACGGCGGTCCCTACGGCAGCCT
CGGCTTTCCGGTGACGGCGATGCACTCGGCGGCGATGGACAAGAGCGTCTTTCCGCCGGGGGCACTGTTGTTCATCCAGG
CCCAGACCCGCGCCGGGATGCTCCGGCAGTTCGTGCTCGACCATGACACGGGGGCGGCCATCCGCGGGCGCGGCCGGTTG
GATCTGTTCGTGGGCACGGGGCCTGAGGCGGAGGACCGGGCCGGGCAGATCAATGCCCCGGCGCGGCTCTACTATCTGTT
GCTCAAAATGCCCGCCAGCATTTGA

Upstream 100 bases:

>100_bases
CGCATCGAGCGGAAGCTAACCCGTGAAACCCCAACCGACTGGGATAATCTCGACGACGATTAGCGCCGCGCTGCTGGCCG
GCTGGCTGGTCTGCGCTCCG

Downstream 100 bases:

>100_bases
TAAGCTAGGTACGCTGTTTTTGGCCCTGGGCCTGACTGGAGAGGCATTTGACACGAGCCACCGAATTGCCGCCTGCACTG
GATACATTTTTGCTGGAGTT

Product: hypothetical protein

Products: Muramic Acid Residue [C]

Alternate protein names: Mlt38; Murein hydrolase A [H]

Number of amino acids: Translated: 354; Mature: 353

Protein sequence:

>354_residues
MARSEEPLLVGASFEEVDLAGGWHDRWTLIKSVDTSLRYLSTPAASRAYPRRGITRERLAASLRRFRAILKTSPSAEAFS
VRVGREFDLYRVNPEPDSPEVLITGYFAPVYRASRKPTATYRYPLYKTPGDLVTDGVRGLGQRTAAGVRPYPTRAQIEKQ
NLLAGRELIWLADPLERFLVHVQGSAKLVLTDGATRSVGFAAKTDRPYQSIGKALVADGKIREEDLTLQAVKAYFRAHPE
ELESYLHKNESYVFFRWTDDGGPYGSLGFPVTAMHSAAMDKSVFPPGALLFIQAQTRAGMLRQFVLDHDTGAAIRGRGRL
DLFVGTGPEAEDRAGQINAPARLYYLLLKMPASI

Sequences:

>Translated_354_residues
MARSEEPLLVGASFEEVDLAGGWHDRWTLIKSVDTSLRYLSTPAASRAYPRRGITRERLAASLRRFRAILKTSPSAEAFS
VRVGREFDLYRVNPEPDSPEVLITGYFAPVYRASRKPTATYRYPLYKTPGDLVTDGVRGLGQRTAAGVRPYPTRAQIEKQ
NLLAGRELIWLADPLERFLVHVQGSAKLVLTDGATRSVGFAAKTDRPYQSIGKALVADGKIREEDLTLQAVKAYFRAHPE
ELESYLHKNESYVFFRWTDDGGPYGSLGFPVTAMHSAAMDKSVFPPGALLFIQAQTRAGMLRQFVLDHDTGAAIRGRGRL
DLFVGTGPEAEDRAGQINAPARLYYLLLKMPASI
>Mature_353_residues
ARSEEPLLVGASFEEVDLAGGWHDRWTLIKSVDTSLRYLSTPAASRAYPRRGITRERLAASLRRFRAILKTSPSAEAFSV
RVGREFDLYRVNPEPDSPEVLITGYFAPVYRASRKPTATYRYPLYKTPGDLVTDGVRGLGQRTAAGVRPYPTRAQIEKQN
LLAGRELIWLADPLERFLVHVQGSAKLVLTDGATRSVGFAAKTDRPYQSIGKALVADGKIREEDLTLQAVKAYFRAHPEE
LESYLHKNESYVFFRWTDDGGPYGSLGFPVTAMHSAAMDKSVFPPGALLFIQAQTRAGMLRQFVLDHDTGAAIRGRGRLD
LFVGTGPEAEDRAGQINAPARLYYLLLKMPASI

Specific function: Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division. Degrades murein glycan strands and insoluble, high-molecular weight murein sacculi [H]

COG id: COG2821

COG function: function code M; Membrane-bound lytic murein transglycosylase

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789179, Length=273, Percent_Identity=28.5714285714286, Blast_Score=111, Evalue=8e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010611
- InterPro:   IPR014733
- InterPro:   IPR005300 [H]

Pfam domain/function: PF06725 3D; PF03562 MltA [H]

EC number: 3.2.1.- [C]

Molecular weight: Translated: 39293; Mature: 39162

Theoretical pI: Translated: 9.93; Mature: 9.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARSEEPLLVGASFEEVDLAGGWHDRWTLIKSVDTSLRYLSTPAASRAYPRRGITRERLA
CCCCCCCEEEECCCCEEECCCCCCHHHHHHHHHHHHHHHHCCCCHHCCCCCCCCCHHHHH
ASLRRFRAILKTSPSAEAFSVRVGREFDLYRVNPEPDSPEVLITGYFAPVYRASRKPTAT
HHHHHHHHHHHCCCCCCEEEEEECCEEEEEEECCCCCCCCEEEEECCHHHHHCCCCCCCE
YRYPLYKTPGDLVTDGVRGLGQRTAAGVRPYPTRAQIEKQNLLAGRELIWLADPLERFLV
EECCCCCCCHHHHHHHHHHCCHHHCCCCCCCCCHHHHHHHHHHCCCEEEEEECHHHHHHE
HVQGSAKLVLTDGATRSVGFAAKTDRPYQSIGKALVADGKIREEDLTLQAVKAYFRAHPE
EECCCEEEEEECCCCCCCCEEECCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCHH
ELESYLHKNESYVFFRWTDDGGPYGSLGFPVTAMHSAAMDKSVFPPGALLFIQAQTRAGM
HHHHHHHCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHCCCCCCCCEEEEEEECHHHHH
LRQFVLDHDTGAAIRGRGRLDLFVGTGPEAEDRAGQINAPARLYYLLLKMPASI
HHHHHHCCCCCCEEECCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHCCCCC
>Mature Secondary Structure 
ARSEEPLLVGASFEEVDLAGGWHDRWTLIKSVDTSLRYLSTPAASRAYPRRGITRERLA
CCCCCCEEEECCCCEEECCCCCCHHHHHHHHHHHHHHHHCCCCHHCCCCCCCCCHHHHH
ASLRRFRAILKTSPSAEAFSVRVGREFDLYRVNPEPDSPEVLITGYFAPVYRASRKPTAT
HHHHHHHHHHHCCCCCCEEEEEECCEEEEEEECCCCCCCCEEEEECCHHHHHCCCCCCCE
YRYPLYKTPGDLVTDGVRGLGQRTAAGVRPYPTRAQIEKQNLLAGRELIWLADPLERFLV
EECCCCCCCHHHHHHHHHHCCHHHCCCCCCCCCHHHHHHHHHHCCCEEEEEECHHHHHHE
HVQGSAKLVLTDGATRSVGFAAKTDRPYQSIGKALVADGKIREEDLTLQAVKAYFRAHPE
EECCCEEEEEECCCCCCCCEEECCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCHH
ELESYLHKNESYVFFRWTDDGGPYGSLGFPVTAMHSAAMDKSVFPPGALLFIQAQTRAGM
HHHHHHHCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHCCCCCCCCEEEEEEECHHHHH
LRQFVLDHDTGAAIRGRGRLDLFVGTGPEAEDRAGQINAPARLYYLLLKMPASI
HHHHHHCCCCCCEEECCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Muramic Acid Residue (N-Acetylmuramic Acid And N-Acetylglucosamine Residues) [C]

Specific reaction: Cleavage Of The Beta-1,4-Glycosidic [C]

General reaction: Cleavage Bond [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]