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The map label for this gene is accA

Identifier: 37522433

GI number: 37522433

Start: 3055116

End: 3056096

Strand: Reverse

Name: accA

Synonym: gvip389

Alternate gene names: 37522433

Gene position: 3056096-3055116 (Counterclockwise)

Preceding gene: 37522435

Following gene: 37522430

Centisome position: 65.6

GC content: 63.4

Gene sequence:

>981_bases
ATGACGCAATCTCGCAGTGCAACACCCGGACCTTCGCTGGATTTCGAGCGCGAGCTGATGGAACTGGAGACGCGCCTCGA
CGACATCCGGCGCTTTGCAGAAGAAAACAACGTCGATGTCTCGACGCAACTGGCCGAGATCGAAGCGCGGGCCGCGGAAC
TGCGCCGCGACCTATACGCCAACCTGCCCCCCAAAGACATTTTGCAGCTGGCCCGCAATCCGAAGCGGCCCAGTACCCTC
GACTACATCCAGCTGTTGTGCGAAGACTGGGTCGAATTGCACGGCGATCGGCTGTTCGGCGACGATCTGGCCCTGGTGGG
GGGCCTGGCGCGCCTGGGGGATCACCCGGTGGTGATCATGGGCCACCAAAAAGGCCGCGACACCAAGGACAACATCCAGC
GCAACTTCGGCATGCCCCAGCCCGAGGGTTACCGCAAAGCTCTGCGCCTGATGGACCACGCCAATCACTTTCAGTTGCCG
ATCATCGCCCTCATCGACACCCCCGGCGCCCACGCCGGTGTCGATGCCGAACAGCGCGGCCAGGGGGAGGCGATTGCCCG
CAACCTCCAGCACATGTTCAGCTACGAGGTGCCCATCCTCTGCGCGGTGATTGGCGAAGGCGGCTCCGGCGGAGCGCTCG
CCATCGGCGTCGGCAACCGCATGCTGATGTTCGAGTACGCCGTCTACTCGGTGATTTCTCCCGACAGCTGCTCGGTGATC
CTCTGGCGCGACAAAAAGCACATCGAGCAGGCCGCCAACGCTCTCAAGATCACCGCCCGCGATCTCAAGCAATTGGGGAT
TGTCGATGAGATCATCCCCGAACCCTCGGGCGGCGCCCACCGCGACCCGCAGCGCGCCGCCGCCAATCTCAAAGAAGCAC
TCCTGCGGCACCTGGATGAACTCTTGACCCTGGACGGCCCTACCCGCCGTACCCAGCGCTACGAAAAATTCCGGGCCATG
GCCCGCTTCCAGGAAATCTGA

Upstream 100 bases:

>100_bases
AGACTCGGCGGAACGCTGGGTCAAAACCAGCATACTGTGCGCCTCGAACGGATGAGCGCCAAGCAACTGCTAGGATGTGC
TCACTCATCGGTCATTCGCC

Downstream 100 bases:

>100_bases
CACCTAGCTACGCAACCCCCCGTTTCAAGGGGGGCGGCGCAGCCGGGGGGATCAGACTTCCTCTTCTATCTGCACTTCCA
GCTGACCGATCTTCGAGCGT

Product: acetyl-CoA carboxylase carboxyltransferase subunit alpha

Products: NA

Alternate protein names: ACCase subunit alpha; Acetyl-CoA carboxylase carboxyltransferase subunit alpha

Number of amino acids: Translated: 326; Mature: 325

Protein sequence:

>326_residues
MTQSRSATPGPSLDFERELMELETRLDDIRRFAEENNVDVSTQLAEIEARAAELRRDLYANLPPKDILQLARNPKRPSTL
DYIQLLCEDWVELHGDRLFGDDLALVGGLARLGDHPVVIMGHQKGRDTKDNIQRNFGMPQPEGYRKALRLMDHANHFQLP
IIALIDTPGAHAGVDAEQRGQGEAIARNLQHMFSYEVPILCAVIGEGGSGGALAIGVGNRMLMFEYAVYSVISPDSCSVI
LWRDKKHIEQAANALKITARDLKQLGIVDEIIPEPSGGAHRDPQRAAANLKEALLRHLDELLTLDGPTRRTQRYEKFRAM
ARFQEI

Sequences:

>Translated_326_residues
MTQSRSATPGPSLDFERELMELETRLDDIRRFAEENNVDVSTQLAEIEARAAELRRDLYANLPPKDILQLARNPKRPSTL
DYIQLLCEDWVELHGDRLFGDDLALVGGLARLGDHPVVIMGHQKGRDTKDNIQRNFGMPQPEGYRKALRLMDHANHFQLP
IIALIDTPGAHAGVDAEQRGQGEAIARNLQHMFSYEVPILCAVIGEGGSGGALAIGVGNRMLMFEYAVYSVISPDSCSVI
LWRDKKHIEQAANALKITARDLKQLGIVDEIIPEPSGGAHRDPQRAAANLKEALLRHLDELLTLDGPTRRTQRYEKFRAM
ARFQEI
>Mature_325_residues
TQSRSATPGPSLDFERELMELETRLDDIRRFAEENNVDVSTQLAEIEARAAELRRDLYANLPPKDILQLARNPKRPSTLD
YIQLLCEDWVELHGDRLFGDDLALVGGLARLGDHPVVIMGHQKGRDTKDNIQRNFGMPQPEGYRKALRLMDHANHFQLPI
IALIDTPGAHAGVDAEQRGQGEAIARNLQHMFSYEVPILCAVIGEGGSGGALAIGVGNRMLMFEYAVYSVISPDSCSVIL
WRDKKHIEQAANALKITARDLKQLGIVDEIIPEPSGGAHRDPQRAAANLKEALLRHLDELLTLDGPTRRTQRYEKFRAMA
RFQEI

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-Co

COG id: COG0825

COG function: function code I; Acetyl-CoA carboxylase alpha subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccA family

Homologues:

Organism=Escherichia coli, GI1786382, Length=308, Percent_Identity=51.6233766233766, Blast_Score=323, Evalue=8e-90,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACCA_GLOVI (Q7NCW2)

Other databases:

- EMBL:   BA000045
- RefSeq:   NP_925810.1
- ProteinModelPortal:   Q7NCW2
- SMR:   Q7NCW2
- GeneID:   2601265
- GenomeReviews:   BA000045_GR
- NMPDR:   fig|251221.1.peg.2864
- HOGENOM:   HBG286557
- OMA:   QLTKDIY
- ProtClustDB:   PRK05724
- BioCyc:   GVIO251221:GLL2864-MONOMER
- BRENDA:   6.4.1.2
- HAMAP:   MF_00823
- InterPro:   IPR001095
- InterPro:   IPR011763
- PANTHER:   PTHR22855:SF3
- PRINTS:   PR01069
- TIGRFAMs:   TIGR00513

Pfam domain/function: PF03255 ACCA

EC number: =6.4.1.2

Molecular weight: Translated: 36469; Mature: 36338

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: PS50989 COA_CT_CTER; PS00605 ATPASE_C

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQSRSATPGPSLDFERELMELETRLDDIRRFAEENNVDVSTQLAEIEARAAELRRDLYA
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHC
NLPPKDILQLARNPKRPSTLDYIQLLCEDWVELHGDRLFGDDLALVGGLARLGDHPVVIM
CCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCEEEE
GHQKGRDTKDNIQRNFGMPQPEGYRKALRLMDHANHFQLPIIALIDTPGAHAGVDAEQRG
ECCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCHHHCC
QGEAIARNLQHMFSYEVPILCAVIGEGGSGGALAIGVGNRMLMFEYAVYSVISPDSCSVI
CHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEECCCCHHHHHHHHHHHCCCCCCEEE
LWRDKKHIEQAANALKITARDLKQLGIVDEIIPEPSGGAHRDPQRAAANLKEALLRHLDE
EECCHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
LLTLDGPTRRTQRYEKFRAMARFQEI
HHHCCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TQSRSATPGPSLDFERELMELETRLDDIRRFAEENNVDVSTQLAEIEARAAELRRDLYA
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHC
NLPPKDILQLARNPKRPSTLDYIQLLCEDWVELHGDRLFGDDLALVGGLARLGDHPVVIM
CCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCEEEE
GHQKGRDTKDNIQRNFGMPQPEGYRKALRLMDHANHFQLPIIALIDTPGAHAGVDAEQRG
ECCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCHHHCC
QGEAIARNLQHMFSYEVPILCAVIGEGGSGGALAIGVGNRMLMFEYAVYSVISPDSCSVI
CHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEECCCCHHHHHHHHHHHCCCCCCEEE
LWRDKKHIEQAANALKITARDLKQLGIVDEIIPEPSGGAHRDPQRAAANLKEALLRHLDE
EECCHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
LLTLDGPTRRTQRYEKFRAMARFQEI
HHHCCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14621292