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The map label for this gene is yafC [C]

Identifier: 37522429

GI number: 37522429

Start: 3049469

End: 3050434

Strand: Reverse

Name: yafC [C]

Synonym: gll2860

Alternate gene names: 37522429

Gene position: 3050434-3049469 (Counterclockwise)

Preceding gene: 37522430

Following gene: 37522427

Centisome position: 65.47

GC content: 67.29

Gene sequence:

>966_bases
ATGACACAGGCAAGAAACAGGGCACTCCCGAGCGACACGAACGACATGGCCATATTTGCCTGCGTCGTCAATCTTGGAAG
CTTTGCACGGACAGCCGAAGAACACAACCTTACCCCTTCGGCCGTCAGCCGTGTCATCTCCCGCCTCGAGCTGCGGCTGG
GCGCGCGGCTGCTGCAGCGCTCCACCCGCAAGCTGTCGCTGACCGAGGCGGGCGCCATCTACCACGCCCGGGTCATACAG
ATCCTGGCAGACGTTGCCGAGGCCGAAGCGGAAGTGGCCGCGGCAAACCTCCAGCCGCGGGGCACTTTGAAGCTGAGCGT
GCCGGTGGTGTTTGGTCGGCTGCACGTGGCACCGCTGATCGGCCGCCTGATGCGGCAGTTTCCCGAACTGGCCGTCGAGC
TGACGCTTACCGACCGGTTTGTCGACCTCATCGAGGAGGGGATCGACCTTGCCCTGCGCATCGGCGCCCTGCCGGACTCC
CGGCTGATGGCCAGGCGCCTTTGCACCAACCGGCGCATACTCGTCGCAAGCCCCGATTACCTGGCCCGCGCCGGCACCCC
CGTCCGCCCCGCCGATCTCACCCGACACTCCTGTTTGATTTTCACGGCGCTCAACCGGCCGCGCGACTGGCGGCTGGTCG
GGCCGGAGGGCACCACGAGCGTCTCGGTGACGGGCCGGTTGAGCGCGAACAACGGCGATGCACTACTCGAAGCGGCCCTC
GAAAGCCTGGGCATCTGTCCGACCGCGACGTTCGTGGCCGCGGAACTGCTGATGCGCGGCGAGCTTGTGCGCGTCTTGCC
GGAGCACGAATTCGAACCGACAGCCGTCCACGCCGTTTACCCCTCGGCCCGGCAGCTCTCCACGAAGGTGCGCAGCGCTG
TCGATTTGCTGGTCAGAACCTTCGCAGATCCGCCGCCCTGGGACAGGCTCCCGGTGCCCGCCCCCCCGCCCCCGGCAAGA
CGCTGA

Upstream 100 bases:

>100_bases
TTGCTCCGCAATTCCCACGTGGTAGGATTACCGAGAATTGCCCAGCACCACCGCCGGGCATCGCCGACATTCGTACGACA
CCGGAATCAGGAGCGCCTGG

Downstream 100 bases:

>100_bases
GCGGGCCGGGGATTTTCCTCGCCCCTCAGCTTGTGACCTGGAGCAACATCTTGCCGGTCGAGGCGCGCGTTTCGAGGGCA
TGCTGGGCCTCGGCCGCCCG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 321; Mature: 320

Protein sequence:

>321_residues
MTQARNRALPSDTNDMAIFACVVNLGSFARTAEEHNLTPSAVSRVISRLELRLGARLLQRSTRKLSLTEAGAIYHARVIQ
ILADVAEAEAEVAAANLQPRGTLKLSVPVVFGRLHVAPLIGRLMRQFPELAVELTLTDRFVDLIEEGIDLALRIGALPDS
RLMARRLCTNRRILVASPDYLARAGTPVRPADLTRHSCLIFTALNRPRDWRLVGPEGTTSVSVTGRLSANNGDALLEAAL
ESLGICPTATFVAAELLMRGELVRVLPEHEFEPTAVHAVYPSARQLSTKVRSAVDLLVRTFADPPPWDRLPVPAPPPPAR
R

Sequences:

>Translated_321_residues
MTQARNRALPSDTNDMAIFACVVNLGSFARTAEEHNLTPSAVSRVISRLELRLGARLLQRSTRKLSLTEAGAIYHARVIQ
ILADVAEAEAEVAAANLQPRGTLKLSVPVVFGRLHVAPLIGRLMRQFPELAVELTLTDRFVDLIEEGIDLALRIGALPDS
RLMARRLCTNRRILVASPDYLARAGTPVRPADLTRHSCLIFTALNRPRDWRLVGPEGTTSVSVTGRLSANNGDALLEAAL
ESLGICPTATFVAAELLMRGELVRVLPEHEFEPTAVHAVYPSARQLSTKVRSAVDLLVRTFADPPPWDRLPVPAPPPPAR
R
>Mature_320_residues
TQARNRALPSDTNDMAIFACVVNLGSFARTAEEHNLTPSAVSRVISRLELRLGARLLQRSTRKLSLTEAGAIYHARVIQI
LADVAEAEAEVAAANLQPRGTLKLSVPVVFGRLHVAPLIGRLMRQFPELAVELTLTDRFVDLIEEGIDLALRIGALPDSR
LMARRLCTNRRILVASPDYLARAGTPVRPADLTRHSCLIFTALNRPRDWRLVGPEGTTSVSVTGRLSANNGDALLEAALE
SLGICPTATFVAAELLMRGELVRVLPEHEFEPTAVHAVYPSARQLSTKVRSAVDLLVRTFADPPPWDRLPVPAPPPPARR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=294, Percent_Identity=38.0952380952381, Blast_Score=181, Evalue=6e-47,
Organism=Escherichia coli, GI87081978, Length=294, Percent_Identity=37.4149659863946, Blast_Score=180, Evalue=1e-46,
Organism=Escherichia coli, GI1789440, Length=290, Percent_Identity=35.5172413793103, Blast_Score=168, Evalue=5e-43,
Organism=Escherichia coli, GI1789639, Length=290, Percent_Identity=33.448275862069, Blast_Score=162, Evalue=4e-41,
Organism=Escherichia coli, GI145693193, Length=277, Percent_Identity=33.2129963898917, Blast_Score=148, Evalue=4e-37,
Organism=Escherichia coli, GI1787128, Length=299, Percent_Identity=31.1036789297659, Blast_Score=137, Evalue=9e-34,
Organism=Escherichia coli, GI1787589, Length=286, Percent_Identity=26.5734265734266, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1788706, Length=267, Percent_Identity=26.5917602996255, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1789173, Length=251, Percent_Identity=26.6932270916335, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1786448, Length=142, Percent_Identity=29.5774647887324, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35050; Mature: 34919

Theoretical pI: Translated: 9.77; Mature: 9.77

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQARNRALPSDTNDMAIFACVVNLGSFARTAEEHNLTPSAVSRVISRLELRLGARLLQR
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
STRKLSLTEAGAIYHARVIQILADVAEAEAEVAAANLQPRGTLKLSVPVVFGRLHVAPLI
HHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHH
GRLMRQFPELAVELTLTDRFVDLIEEGIDLALRIGALPDSRLMARRLCTNRRILVASPDY
HHHHHHHHHHEEEEEHHHHHHHHHHHCHHEEEEECCCCCHHHHHHHHHCCCEEEEECCCH
LARAGTPVRPADLTRHSCLIFTALNRPRDWRLVGPEGTTSVSVTGRLSANNGDALLEAAL
HHHCCCCCCCCCCCCCCEEEEEECCCCCCEEEECCCCCCEEEEEEEEECCCCHHHHHHHH
ESLGICPTATFVAAELLMRGELVRVLPEHEFEPTAVHAVYPSARQLSTKVRSAVDLLVRT
HHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHH
FADPPPWDRLPVPAPPPPARR
HCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TQARNRALPSDTNDMAIFACVVNLGSFARTAEEHNLTPSAVSRVISRLELRLGARLLQR
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
STRKLSLTEAGAIYHARVIQILADVAEAEAEVAAANLQPRGTLKLSVPVVFGRLHVAPLI
HHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHH
GRLMRQFPELAVELTLTDRFVDLIEEGIDLALRIGALPDSRLMARRLCTNRRILVASPDY
HHHHHHHHHHEEEEEHHHHHHHHHHHCHHEEEEECCCCCHHHHHHHHHCCCEEEEECCCH
LARAGTPVRPADLTRHSCLIFTALNRPRDWRLVGPEGTTSVSVTGRLSANNGDALLEAAL
HHHCCCCCCCCCCCCCCEEEEEECCCCCCEEEECCCCCCEEEEEEEEECCCCHHHHHHHH
ESLGICPTATFVAAELLMRGELVRVLPEHEFEPTAVHAVYPSARQLSTKVRSAVDLLVRT
HHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHH
FADPPPWDRLPVPAPPPPARR
HCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8635745; 7542800 [H]