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The map label for this gene is pksE [H]

Identifier: 37522400

GI number: 37522400

Start: 3014976

End: 3016643

Strand: Reverse

Name: pksE [H]

Synonym: gll2831

Alternate gene names: 37522400

Gene position: 3016643-3014976 (Counterclockwise)

Preceding gene: 37522401

Following gene: 37522399

Centisome position: 64.75

GC content: 65.11

Gene sequence:

>1668_bases
GTGCCACAATCCAACCGTCTCGAATATTTGGGTTTCTGCTTCAACCCCTACCAGTCCTGGGAAGGTCCGCTGGAGTCGGT
TGCCTTCGACGAAGAGGCTATGCGGGCGATGGCGCTCGATGGGGACCGGCCGCTGTACGTCGTCAAAATCGACGAGCGCG
TCGGCATGGCCCAAAGCGGCGGCCCCGCTCCCACCGGGCGCGGCAGGACCGCCACGGCCCAACTGCTCTTGAAGGCGCCG
CCGCTGTTGCCCGAGCAACTCGGGGACGATCGCTTCCGGATCGATCACGGGGTCAAGTATGCCTATGTTACTGGGGCGAT
GGCCAACGGCATCGCTTCGGAGGAGATGGTGATTGCCCTCGGCCGCGAGCGCCTGCTCGGGTCGTTCGGGGCGGCCGGGC
TGGTGCCTGAGCGCATCGAAGCGGCAATCCAGCGGATCCAGCAGGCGCTGCCGACGGGACCCTACGCATTCAACTTGATC
CACAGCCCCAGCGAAGCGGCGATCGAGCGAGGGGCGGTCGATCTCTATCTCAAATACGCCGTGACGACGGTCGAAGCCTC
GGCATTTATGGATCTCACCCCGAGCATCGTCCGCTACCGGGCAGCCGGGTTGAGTCGCCGGGGCGACGAGGTCGCGATCG
GCAACAAGATCATCGCCAAAGTGTCCCGCCCGGAAGTGGCGACGCGCTTTTTGCAGCCCGCTCCGCACCCTGTGCTCAAA
CAACTGGTCGAAAGCGGCCAGATCAGCGAACTGCAGGCCCAACTGGCCGAGCAGGTGCCGATGTGCGACGACCTCACCGT
CGAAGCCGACTCGGGCGGCCATACCGACAACCGGCCTCTGGTCTGCCTGCTGCCGGCCATCATCGCCCTGCGCGACGAGA
TCCAGGAGCGCTTCGGTTACACCCGGCCGGTGCGGGTGGGTGCAGCCGGCGGTATCGGCACCCCCCACGCGGTCCAGGCC
GCCTTCGCGATGGGGGCCGCCTACGTGGTGACCGGTTCGGTCAACCAGGCGTGCACAGAAGCCGGCGCCTCCCGCCACAC
CAAGCAACTGCTGGCCCAGGCCGATCTGGCCGATGTGGCGATGGCCCCGGCCGCCGATATGTTCGAATTGGGCGTCAAGC
TGCAGGTGCTCAAGCGGGGCACCCTGTTTGCCAGCCGTGCCCAGAAGCTTTTTGAGCTGTACAGAACCCACGAGTCGCTG
GAAGCCATCCCCGGCCCCGAGCGCGAGAAGCTCGAAAAGCAAATCTTCCGCCAGCCTTTAGAGGCGATCTGGCGGGATAC
CGTCGCCTATTTCACAAGCCGCGATCCCGACCAGATCCAGCGGGCCACGGACAACCCCAAGCGCAAAATGGCGCTGGTTT
TTCGCTGGTACCTGGGTCTTTCTTCGCGCTGGTCCAACACCGGTGAACCGGGCCGCGAGGCGGATTACCAGATCTGGTGC
GGTCCGGCGATGGGTGCGTTCAACCATTGGGTAAAAACCACCTACCTCGCCGAGCCCGCCAACCGCAGCGTCCTGGACGT
GGCCTGGCACCTGATGCGCGGAGCGGCTTTGCTGCAGCGCCTCGAAGGGATGCGCCTGCAGGGCCTGCGCATCCCGGGTT
CCTGGAACCAGTACCGGCCCGTCGCCAGAGCTATGCAATCGAGTCGTGTTTTAGAGGTACACCGATGA

Upstream 100 bases:

>100_bases
CAAATCGAGCTGGCGCGCCGGCTGGCGGCACCCGGCCGCAGCCCTCTGCGCTGATGGGTGGCCTACCGGACAACCGTTCT
ATTTCTCAAGGAGGCGCACC

Downstream 100 bases:

>100_bases
GCCCGATGTCTTCCCAGTCCAGCCTCAAGCCGATCGCCGGCGCCGCCCTCATCCAGGAGTGGCTGAAAGCCAAACTGAGC
GAGCGGCTGAAAATCTCCAC

Product: hypothetical protein

Products: NA

Alternate protein names: Malonyl CoA-acyl carrier protein transacylase; MCT [H]

Number of amino acids: Translated: 555; Mature: 554

Protein sequence:

>555_residues
MPQSNRLEYLGFCFNPYQSWEGPLESVAFDEEAMRAMALDGDRPLYVVKIDERVGMAQSGGPAPTGRGRTATAQLLLKAP
PLLPEQLGDDRFRIDHGVKYAYVTGAMANGIASEEMVIALGRERLLGSFGAAGLVPERIEAAIQRIQQALPTGPYAFNLI
HSPSEAAIERGAVDLYLKYAVTTVEASAFMDLTPSIVRYRAAGLSRRGDEVAIGNKIIAKVSRPEVATRFLQPAPHPVLK
QLVESGQISELQAQLAEQVPMCDDLTVEADSGGHTDNRPLVCLLPAIIALRDEIQERFGYTRPVRVGAAGGIGTPHAVQA
AFAMGAAYVVTGSVNQACTEAGASRHTKQLLAQADLADVAMAPAADMFELGVKLQVLKRGTLFASRAQKLFELYRTHESL
EAIPGPEREKLEKQIFRQPLEAIWRDTVAYFTSRDPDQIQRATDNPKRKMALVFRWYLGLSSRWSNTGEPGREADYQIWC
GPAMGAFNHWVKTTYLAEPANRSVLDVAWHLMRGAALLQRLEGMRLQGLRIPGSWNQYRPVARAMQSSRVLEVHR

Sequences:

>Translated_555_residues
MPQSNRLEYLGFCFNPYQSWEGPLESVAFDEEAMRAMALDGDRPLYVVKIDERVGMAQSGGPAPTGRGRTATAQLLLKAP
PLLPEQLGDDRFRIDHGVKYAYVTGAMANGIASEEMVIALGRERLLGSFGAAGLVPERIEAAIQRIQQALPTGPYAFNLI
HSPSEAAIERGAVDLYLKYAVTTVEASAFMDLTPSIVRYRAAGLSRRGDEVAIGNKIIAKVSRPEVATRFLQPAPHPVLK
QLVESGQISELQAQLAEQVPMCDDLTVEADSGGHTDNRPLVCLLPAIIALRDEIQERFGYTRPVRVGAAGGIGTPHAVQA
AFAMGAAYVVTGSVNQACTEAGASRHTKQLLAQADLADVAMAPAADMFELGVKLQVLKRGTLFASRAQKLFELYRTHESL
EAIPGPEREKLEKQIFRQPLEAIWRDTVAYFTSRDPDQIQRATDNPKRKMALVFRWYLGLSSRWSNTGEPGREADYQIWC
GPAMGAFNHWVKTTYLAEPANRSVLDVAWHLMRGAALLQRLEGMRLQGLRIPGSWNQYRPVARAMQSSRVLEVHR
>Mature_554_residues
PQSNRLEYLGFCFNPYQSWEGPLESVAFDEEAMRAMALDGDRPLYVVKIDERVGMAQSGGPAPTGRGRTATAQLLLKAPP
LLPEQLGDDRFRIDHGVKYAYVTGAMANGIASEEMVIALGRERLLGSFGAAGLVPERIEAAIQRIQQALPTGPYAFNLIH
SPSEAAIERGAVDLYLKYAVTTVEASAFMDLTPSIVRYRAAGLSRRGDEVAIGNKIIAKVSRPEVATRFLQPAPHPVLKQ
LVESGQISELQAQLAEQVPMCDDLTVEADSGGHTDNRPLVCLLPAIIALRDEIQERFGYTRPVRVGAAGGIGTPHAVQAA
FAMGAAYVVTGSVNQACTEAGASRHTKQLLAQADLADVAMAPAADMFELGVKLQVLKRGTLFASRAQKLFELYRTHESLE
AIPGPEREKLEKQIFRQPLEAIWRDTVAYFTSRDPDQIQRATDNPKRKMALVFRWYLGLSSRWSNTGEPGREADYQIWCG
PAMGAFNHWVKTTYLAEPANRSVLDVAWHLMRGAALLQRLEGMRLQGLRIPGSWNQYRPVARAMQSSRVLEVHR

Specific function: Probably involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism. Probably has an acyl transferase activity and could also have a flavin mononucleotide-dependent oxidoreductas

COG id: COG2070

COG function: function code R; Dioxygenases related to 2-nitropropane dioxygenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: In the N-terminal section; belongs to the fabD family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004136
- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR013785
- InterPro:   IPR004410
- InterPro:   IPR016036
- InterPro:   IPR014179 [H]

Pfam domain/function: PF00698 Acyl_transf_1; PF03060 NPD [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 61074; Mature: 60942

Theoretical pI: Translated: 7.93; Mature: 7.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQSNRLEYLGFCFNPYQSWEGPLESVAFDEEAMRAMALDGDRPLYVVKIDERVGMAQSG
CCCCCCCEEEEEEECCHHHCCCCHHHHHCCHHHHHHHHCCCCCCEEEEEECCCCCCCCCC
GPAPTGRGRTATAQLLLKAPPLLPEQLGDDRFRIDHGVKYAYVTGAMANGIASEEMVIAL
CCCCCCCCCHHHHHHHHCCCCCCHHHCCCCCEECCCCEEEEEEECHHHCCCCCCHHHHHH
GRERLLGSFGAAGLVPERIEAAIQRIQQALPTGPYAFNLIHSPSEAAIERGAVDLYLKYA
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHCCCHHEEEEHH
VTTVEASAFMDLTPSIVRYRAAGLSRRGDEVAIGNKIIAKVSRPEVATRFLQPAPHPVLK
HHHHHHHHHHCCCHHHHHHHHHCCCCCCCCEEECCHHHHHCCCHHHHHHHHCCCCCHHHH
QLVESGQISELQAQLAEQVPMCDDLTVEADSGGHTDNRPLVCLLPAIIALRDEIQERFGY
HHHHCCCHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
TRPVRVGAAGGIGTPHAVQAAFAMGAAYVVTGSVNQACTEAGASRHTKQLLAQADLADVA
CCCEEEECCCCCCCHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHH
MAPAADMFELGVKLQVLKRGTLFASRAQKLFELYRTHESLEAIPGPEREKLEKQIFRQPL
HCCCHHHHHHCCHHEEHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
EAIWRDTVAYFTSRDPDQIQRATDNPKRKMALVFRWYLGLSSRWSNTGEPGREADYQIWC
HHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEE
GPAMGAFNHWVKTTYLAEPANRSVLDVAWHLMRGAALLQRLEGMRLQGLRIPGSWNQYRP
CCHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHH
VARAMQSSRVLEVHR
HHHHHHHCCCEECCC
>Mature Secondary Structure 
PQSNRLEYLGFCFNPYQSWEGPLESVAFDEEAMRAMALDGDRPLYVVKIDERVGMAQSG
CCCCCCEEEEEEECCHHHCCCCHHHHHCCHHHHHHHHCCCCCCEEEEEECCCCCCCCCC
GPAPTGRGRTATAQLLLKAPPLLPEQLGDDRFRIDHGVKYAYVTGAMANGIASEEMVIAL
CCCCCCCCCHHHHHHHHCCCCCCHHHCCCCCEECCCCEEEEEEECHHHCCCCCCHHHHHH
GRERLLGSFGAAGLVPERIEAAIQRIQQALPTGPYAFNLIHSPSEAAIERGAVDLYLKYA
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHCCCHHEEEEHH
VTTVEASAFMDLTPSIVRYRAAGLSRRGDEVAIGNKIIAKVSRPEVATRFLQPAPHPVLK
HHHHHHHHHHCCCHHHHHHHHHCCCCCCCCEEECCHHHHHCCCHHHHHHHHCCCCCHHHH
QLVESGQISELQAQLAEQVPMCDDLTVEADSGGHTDNRPLVCLLPAIIALRDEIQERFGY
HHHHCCCHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
TRPVRVGAAGGIGTPHAVQAAFAMGAAYVVTGSVNQACTEAGASRHTKQLLAQADLADVA
CCCEEEECCCCCCCHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHH
MAPAADMFELGVKLQVLKRGTLFASRAQKLFELYRTHESLEAIPGPEREKLEKQIFRQPL
HCCCHHHHHHCCHHEEHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
EAIWRDTVAYFTSRDPDQIQRATDNPKRKMALVFRWYLGLSSRWSNTGEPGREADYQIWC
HHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEE
GPAMGAFNHWVKTTYLAEPANRSVLDVAWHLMRGAALLQRLEGMRLQGLRIPGSWNQYRP
CCHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHH
VARAMQSSRVLEVHR
HHHHHHHCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]