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The map label for this gene is pilC [H]

Identifier: 37522234

GI number: 37522234

Start: 2825985

End: 2827217

Strand: Reverse

Name: pilC [H]

Synonym: gvip375

Alternate gene names: 37522234

Gene position: 2827217-2825985 (Counterclockwise)

Preceding gene: 37522235

Following gene: 37522233

Centisome position: 60.68

GC content: 61.64

Gene sequence:

>1233_bases
ATGCCGCAATTCAAGTACCGCGTGCGCGACTACCGGGGGACCGCCATCGAGGAGACCGTCGAGGCCGACAGCGCCGTCAC
GCTGCGCACGCGCCTGCGCGAGCAGGGCATGTACGTGCTGCAGATTGCCGAGGTCCAGCCGAGCGCCCTGCAGGGGGCTT
TTTCGCTGGAGGCGCTCCAGACGGCCACCACCCGCATCACCATCCGCGACAAGTCGCTGTTTGCCCGTCAGCTCGCGGCG
ATGACCAGCGCCGGCGTCTCGCTGGTGCGCTCGCTGACGGTGCTCGAAGAGCAGTCGACCAACCGCAAGCTCAAAAAAGT
GCTCACCCAGGTGAGCTTCGACGTCCAGCAGGGCAGCAGCCTTGCCGCCTCGATGCGCAAGTTTCCCCAGGCTTTCGACA
ACCTGTTCGTGGCGATGATCCAGGCGGGCGAAGCCGGGGGGCTGCTCGATCAGGTGCTCGACCGGCTCTCCAAGTTGCTT
GAAGACCAAGACCGTCTGCAGCGGCAGGTGCGATCCGCCCTCGCCTATCCGGTTACGGTGCTTATCCTCGCGGTGATTAT
TTTCCTGGCGATGGTGACGTTCATCCTGCCGGTCTTCAAGGACATCTTCAAGCAACTCGGGGGCGAATTACCCGCCTTTA
CCCAGACGTTGATGGGCCTGAGCGAACTGCTGCAAAACCCGTTTGCCTGGGCGTTTTTGATTGTCGCCGGCAGTGGGATC
ACCTGGCTGTACCGGCGCTACAACAATTCCCCCGGCGGCAGGCGGGTGGTCGACCGCATCAAGCTTGCTCTGCCTTTGTT
TGGCGATTTGATTCAAAAAGCCTCGGTGGCTCGCTTCTGCCGCACGTTCGGCTCGCTGGTGCGATCCGGGGTGCCTATCC
TCAGTGCCCTGGAGATCGTCCGCGACACCGCCGGCAATGCCGTGATCGCCGACGCCGTGGATGAAGCGCGCCGGGTGATC
CGCGAAGGCAGTCTGATTAGCCCCACCCTCAAAAAAGAAAAAGCCTTTCCGCCCATGGCAGTACAGATGATCAGCGTCGG
CGAAGAGTCGGGCGAACTCGACAGCATGCTGATGAAAGTCGCCGATTTCTACGAATCGGAAGTCGAGCAGGCGGTCAAGG
CGCTTACCAGTTTGCTGGAGCCCATCATGATCGTGGTACTCGGGGGACTGGTGGGCTCGGTCATTCTGGCGATGTACCTG
CCGCTGTTTACGGTCTTCGACTTGATCAAGTAG

Upstream 100 bases:

>100_bases
CGGCGGGCCGTCCGGCCGTCGGCCCCGGCGGCGGCGGTGGTTCCCGCCCCTCGTTCACCCAGCCCATCACCAACCGCTAA
GCTGCCTTTGAGCGACCGCT

Downstream 100 bases:

>100_bases
TGCGCCCAGAACCGGAGCTCTCGGCGTACCGGGAGCGGTCAAGCCGGAAAAGCATCCAGGCCGTATCTACGGAATCCCAG
AAATAGAGGGTGTTGGTTCA

Product: pilin biogenesis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 410; Mature: 409

Protein sequence:

>410_residues
MPQFKYRVRDYRGTAIEETVEADSAVTLRTRLREQGMYVLQIAEVQPSALQGAFSLEALQTATTRITIRDKSLFARQLAA
MTSAGVSLVRSLTVLEEQSTNRKLKKVLTQVSFDVQQGSSLAASMRKFPQAFDNLFVAMIQAGEAGGLLDQVLDRLSKLL
EDQDRLQRQVRSALAYPVTVLILAVIIFLAMVTFILPVFKDIFKQLGGELPAFTQTLMGLSELLQNPFAWAFLIVAGSGI
TWLYRRYNNSPGGRRVVDRIKLALPLFGDLIQKASVARFCRTFGSLVRSGVPILSALEIVRDTAGNAVIADAVDEARRVI
REGSLISPTLKKEKAFPPMAVQMISVGEESGELDSMLMKVADFYESEVEQAVKALTSLLEPIMIVVLGGLVGSVILAMYL
PLFTVFDLIK

Sequences:

>Translated_410_residues
MPQFKYRVRDYRGTAIEETVEADSAVTLRTRLREQGMYVLQIAEVQPSALQGAFSLEALQTATTRITIRDKSLFARQLAA
MTSAGVSLVRSLTVLEEQSTNRKLKKVLTQVSFDVQQGSSLAASMRKFPQAFDNLFVAMIQAGEAGGLLDQVLDRLSKLL
EDQDRLQRQVRSALAYPVTVLILAVIIFLAMVTFILPVFKDIFKQLGGELPAFTQTLMGLSELLQNPFAWAFLIVAGSGI
TWLYRRYNNSPGGRRVVDRIKLALPLFGDLIQKASVARFCRTFGSLVRSGVPILSALEIVRDTAGNAVIADAVDEARRVI
REGSLISPTLKKEKAFPPMAVQMISVGEESGELDSMLMKVADFYESEVEQAVKALTSLLEPIMIVVLGGLVGSVILAMYL
PLFTVFDLIK
>Mature_409_residues
PQFKYRVRDYRGTAIEETVEADSAVTLRTRLREQGMYVLQIAEVQPSALQGAFSLEALQTATTRITIRDKSLFARQLAAM
TSAGVSLVRSLTVLEEQSTNRKLKKVLTQVSFDVQQGSSLAASMRKFPQAFDNLFVAMIQAGEAGGLLDQVLDRLSKLLE
DQDRLQRQVRSALAYPVTVLILAVIIFLAMVTFILPVFKDIFKQLGGELPAFTQTLMGLSELLQNPFAWAFLIVAGSGIT
WLYRRYNNSPGGRRVVDRIKLALPLFGDLIQKASVARFCRTFGSLVRSGVPILSALEIVRDTAGNAVIADAVDEARRVIR
EGSLISPTLKKEKAFPPMAVQMISVGEESGELDSMLMKVADFYESEVEQAVKALTSLLEPIMIVVLGGLVGSVILAMYLP
LFTVFDLIK

Specific function: Involved in the translocation of the type IV pilin (pilA) [H]

COG id: COG1459

COG function: function code NU; Type II secretory pathway, component PulF

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP F family [H]

Homologues:

Organism=Escherichia coli, GI1789724, Length=411, Percent_Identity=29.1970802919708, Blast_Score=201, Evalue=5e-53,
Organism=Escherichia coli, GI1786295, Length=337, Percent_Identity=29.673590504451, Blast_Score=158, Evalue=5e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003004
- InterPro:   IPR018076
- InterPro:   IPR001992 [H]

Pfam domain/function: PF00482 GSPII_F [H]

EC number: NA

Molecular weight: Translated: 45174; Mature: 45042

Theoretical pI: Translated: 9.45; Mature: 9.45

Prosite motif: PS00874 T2SP_F

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQFKYRVRDYRGTAIEETVEADSAVTLRTRLREQGMYVLQIAEVQPSALQGAFSLEALQ
CCCCHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHH
TATTRITIRDKSLFARQLAAMTSAGVSLVRSLTVLEEQSTNRKLKKVLTQVSFDVQQGSS
HHHHEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
LAASMRKFPQAFDNLFVAMIQAGEAGGLLDQVLDRLSKLLEDQDRLQRQVRSALAYPVTV
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LILAVIIFLAMVTFILPVFKDIFKQLGGELPAFTQTLMGLSELLQNPFAWAFLIVAGSGI
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCH
TWLYRRYNNSPGGRRVVDRIKLALPLFGDLIQKASVARFCRTFGSLVRSGVPILSALEIV
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
RDTAGNAVIADAVDEARRVIREGSLISPTLKKEKAFPPMAVQMISVGEESGELDSMLMKV
HHCCCCEEHHHHHHHHHHHHHCCCCCCCHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHH
ADFYESEVEQAVKALTSLLEPIMIVVLGGLVGSVILAMYLPLFTVFDLIK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
PQFKYRVRDYRGTAIEETVEADSAVTLRTRLREQGMYVLQIAEVQPSALQGAFSLEALQ
CCCHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHH
TATTRITIRDKSLFARQLAAMTSAGVSLVRSLTVLEEQSTNRKLKKVLTQVSFDVQQGSS
HHHHEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
LAASMRKFPQAFDNLFVAMIQAGEAGGLLDQVLDRLSKLLEDQDRLQRQVRSALAYPVTV
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LILAVIIFLAMVTFILPVFKDIFKQLGGELPAFTQTLMGLSELLQNPFAWAFLIVAGSGI
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCH
TWLYRRYNNSPGGRRVVDRIKLALPLFGDLIQKASVARFCRTFGSLVRSGVPILSALEIV
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
RDTAGNAVIADAVDEARRVIREGSLISPTLKKEKAFPPMAVQMISVGEESGELDSMLMKV
HHCCCCEEHHHHHHHHHHHHHCCCCCCCHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHH
ADFYESEVEQAVKALTSLLEPIMIVVLGGLVGSVILAMYLPLFTVFDLIK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1971619; 10984043 [H]