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The map label for this gene is hldE [H]

Identifier: 37522210

GI number: 37522210

Start: 2797126

End: 2798130

Strand: Direct

Name: hldE [H]

Synonym: glr2641

Alternate gene names: 37522210

Gene position: 2797126-2798130 (Clockwise)

Preceding gene: 37522209

Following gene: 37522211

Centisome position: 60.04

GC content: 67.16

Gene sequence:

>1005_bases
TTGGGCTTAAGAGACGATTTGCATCGACTCATCGACCGCCTTGCCGGTCGGCGGGTGCTGGTGGTGGGAGACCTGACCCT
CGACGAATTTATGACCGGGCTTGCGGAGCGCATCTCGCGCGAGGGGCCGGTGCTCATCTTGCGCCACGAACACACCCGCC
AAGTCCCCGGAGGGGCCGCCAACGCCGCCTACAATCTTGCCCGGCTCGGAGCGCAGGTGGCGGTTGCCGGAGTAACCGGC
CAGGACAGCCAGGCGGCGGCCCTCAAAACCTTACTCGCCGAGGCCGGTATCGACGTGAGCGGCCTGGTGACGGATGCGGA
GCGTCCGACCGTCACCAAGACCCGCATCGCAGCCCACAGTCGCCAGTCGGTCACCCAGCAGGTGGTGCGCATCGACCGCA
AATCCGACCGACCGCTGCCGCCGCCACTGGCCCGGCAACTGGCCGAGCGCATTGGCGAGTTGGCCGGCAGTTGCGCCGCC
GTCGTCTGCTCCGACTACTCCGAAGGCGTATTCTCCGACAAGACGATCGCTGCGTCCCTCCTGCACCCGTGCGTGGTCGT
CGATACCCACCTGCACCCGGAGCGCTATCACGGCGCCACGGTCTTTACGCCCAATCTGCCGGAGGCGGAGACGGCAGTGG
GCTACCCGATCCAGGATGCGGGTACGCTGCTGCGGGCAGGGCAGGAGCTGCTCATCCGCACCGGTGCCCGGCACATGCTC
ATCACCCGCGGCGAAGAAGGCATGAGCTTGTTTAGCGCCGGGGAGGCCGAGGCGCGGCACATCCCGGCTTTTAACCGCAC
CCAGGTTTTCGATGTGACCGGTGCGGGCGATACGGTGGTGGCGGCATTTACCCTGGCGCTGGTGAGCGGCGGCAGCGCTT
ACCAGGCAACAATCCTGGGCAATCTGGCCGCGAGCATCGTCGTGCGCCGCCTTGGCACCGCCACCACCCACCCCGACGAA
CTGCACGCCCACCTCGAGGAGCTGGAGTGGACGAGCGGGTTTTGA

Upstream 100 bases:

>100_bases
TGTCCACCCGGCGGTATGTACCGCCGGGTGGTCTCTCGCTACCGCCGTTCGCGGTGCGCAGCGGGCGTGATAGATTTGTC
TGGGTTTCGGGGTAGGACGT

Downstream 100 bases:

>100_bases
GCGTCGGGGCGCTCCAGCAGCTTCTTGCAGCCGAGCCCGAGCGCTGGCGTCCGCTGGTGCTCACCAACGGCTGCTTCGAC
ATCCTGCACGCGGGCCATGT

Product: hypothetical protein

Products: NA

Alternate protein names: D-beta-D-heptose 7-phosphate kinase; D-beta-D-heptose 7-phosphotransferase; D-beta-D-heptose 1-phosphate adenosyltransferase [H]

Number of amino acids: Translated: 334; Mature: 333

Protein sequence:

>334_residues
MGLRDDLHRLIDRLAGRRVLVVGDLTLDEFMTGLAERISREGPVLILRHEHTRQVPGGAANAAYNLARLGAQVAVAGVTG
QDSQAAALKTLLAEAGIDVSGLVTDAERPTVTKTRIAAHSRQSVTQQVVRIDRKSDRPLPPPLARQLAERIGELAGSCAA
VVCSDYSEGVFSDKTIAASLLHPCVVVDTHLHPERYHGATVFTPNLPEAETAVGYPIQDAGTLLRAGQELLIRTGARHML
ITRGEEGMSLFSAGEAEARHIPAFNRTQVFDVTGAGDTVVAAFTLALVSGGSAYQATILGNLAASIVVRRLGTATTHPDE
LHAHLEELEWTSGF

Sequences:

>Translated_334_residues
MGLRDDLHRLIDRLAGRRVLVVGDLTLDEFMTGLAERISREGPVLILRHEHTRQVPGGAANAAYNLARLGAQVAVAGVTG
QDSQAAALKTLLAEAGIDVSGLVTDAERPTVTKTRIAAHSRQSVTQQVVRIDRKSDRPLPPPLARQLAERIGELAGSCAA
VVCSDYSEGVFSDKTIAASLLHPCVVVDTHLHPERYHGATVFTPNLPEAETAVGYPIQDAGTLLRAGQELLIRTGARHML
ITRGEEGMSLFSAGEAEARHIPAFNRTQVFDVTGAGDTVVAAFTLALVSGGSAYQATILGNLAASIVVRRLGTATTHPDE
LHAHLEELEWTSGF
>Mature_333_residues
GLRDDLHRLIDRLAGRRVLVVGDLTLDEFMTGLAERISREGPVLILRHEHTRQVPGGAANAAYNLARLGAQVAVAGVTGQ
DSQAAALKTLLAEAGIDVSGLVTDAERPTVTKTRIAAHSRQSVTQQVVRIDRKSDRPLPPPLARQLAERIGELAGSCAAV
VCSDYSEGVFSDKTIAASLLHPCVVVDTHLHPERYHGATVFTPNLPEAETAVGYPIQDAGTLLRAGQELLIRTGARHMLI
TRGEEGMSLFSAGEAEARHIPAFNRTQVFDVTGAGDTVVAAFTLALVSGGSAYQATILGNLAASIVVRRLGTATTHPDEL
HAHLEELEWTSGF

Specific function: Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose [H]

COG id: COG2870

COG function: function code M; ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the cytidylyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1789432, Length=308, Percent_Identity=36.6883116883117, Blast_Score=168, Evalue=5e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023030
- InterPro:   IPR011611
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR011913
- InterPro:   IPR011914
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01467 CTP_transf_2; PF00294 PfkB [H]

EC number: 2.7.-.-

Molecular weight: Translated: 35560; Mature: 35429

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: PS00583 PFKB_KINASES_1 ; PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLRDDLHRLIDRLAGRRVLVVGDLTLDEFMTGLAERISREGPVLILRHEHTRQVPGGAA
CCCHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCH
NAAYNLARLGAQVAVAGVTGQDSQAAALKTLLAEAGIDVSGLVTDAERPTVTKTRIAAHS
HHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHH
RQSVTQQVVRIDRKSDRPLPPPLARQLAERIGELAGSCAAVVCSDYSEGVFSDKTIAASL
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCHHHHHHCCCCCCCCCCCHHHHHHH
LHPCVVVDTHLHPERYHGATVFTPNLPEAETAVGYPIQDAGTLLRAGQELLIRTGARHML
HCCEEEEECCCCCHHHCCCEEECCCCCCCHHHCCCCCHHHHHHHHHCHHHHHHCCCCEEE
ITRGEEGMSLFSAGEAEARHIPAFNRTQVFDVTGAGDTVVAAFTLALVSGGSAYQATILG
EECCCCCCHHHHCCCCCHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCCEEHHHHH
NLAASIVVRRLGTATTHPDELHAHLEELEWTSGF
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
GLRDDLHRLIDRLAGRRVLVVGDLTLDEFMTGLAERISREGPVLILRHEHTRQVPGGAA
CCHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCH
NAAYNLARLGAQVAVAGVTGQDSQAAALKTLLAEAGIDVSGLVTDAERPTVTKTRIAAHS
HHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHH
RQSVTQQVVRIDRKSDRPLPPPLARQLAERIGELAGSCAAVVCSDYSEGVFSDKTIAASL
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCHHHHHHCCCCCCCCCCCHHHHHHH
LHPCVVVDTHLHPERYHGATVFTPNLPEAETAVGYPIQDAGTLLRAGQELLIRTGARHML
HCCEEEEECCCCCHHHCCCEEECCCCCCCHHHCCCCCHHHHHHHHHCHHHHHHCCCCEEE
ITRGEEGMSLFSAGEAEARHIPAFNRTQVFDVTGAGDTVVAAFTLALVSGGSAYQATILG
EECCCCCCHHHHCCCCCHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCCEEHHHHH
NLAASIVVRRLGTATTHPDELHAHLEELEWTSGF
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA