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The map label for this gene is codA [H]

Identifier: 37522097

GI number: 37522097

Start: 2683467

End: 2684753

Strand: Reverse

Name: codA [H]

Synonym: gll2528

Alternate gene names: 37522097

Gene position: 2684753-2683467 (Counterclockwise)

Preceding gene: 37522098

Following gene: 37522094

Centisome position: 57.62

GC content: 65.5

Gene sequence:

>1287_bases
ATGCTGGATCTGATCATTCGCGGGGGCAATCTGCCGGACGGGAGCGGCCCGGTGGATATCGCCGTTGCGGATGGTCGGAT
TGCGGCGATTGCCCCTCGCCTCGAAGCGGAGGCCCGCGAGCAGATTGACGCCCATGGGCGATTGGTGAGCCCACCCTTCA
TCGACAGCCACTTTCACATCGATTCGACGCTTACCTTCGGTCGACCACGGGTCAACGCAAGCGGCACGCTGCTGGAAGGG
ATCGCATTGTGGGGCGAGTTGCGCCCGCAGCTAACCTTCGAAGAAATCAAAGGGAGGGCCCTCGGGTTCTGCCGGTGGGC
CATCGCCCGCGGCAACCTGGCCGTCCGCAGCCACGTCGATGTGTGCGATCCGACTCTCACGGCGGTGCAGGCGCTGCTCG
AGGTGCGCGCCCAGATCAAGCCCTACTTGGATCTGCAACTGGTCGCCTTTCCCCAGCAGGGCTACTTGCGCTACCGCGAA
GCGCCCGGACTGCTCGAACGCGCCCTGGATCTGGGGGTGGAGGTGGTCGGGGGCATTCCCCACTTCGAGCGCACCGCCGC
CGAGGGTGCGCTCTCGGTGCGCAAGCTGTGCGAACTGGCCGCCGAGCGCGGATTGCCCGTCGATATGCACTGCGACGAGA
GCGACGATCCCCACTCGCGTTTTGTCGAAAACCTCGCCTGCGAAACGGAGCGGCTGGGGCTGCAGGGTAGGGTGACAGGT
TCGCACCTCACCTCTCTCCACTCGATGGACAATTACTACGCCGGCAAGCTCATCGACCTGATGGCCGAGGCGCGCTTGAA
CGTGGTGGCTAATCCGCTCATCAACATCACCCTGCAGGGTCGTCACGACACCTACCCGAAGCGGCGGGGCCTGACCCGCA
TCCGCGAGCAGATGGCAGCGGGGCTCACCGTCGCCCTGGGCCACGACTGCGTGCTGGATCCGTGGTATCCGCTGGGTAGC
CACGACATGCTCGAAGTGGTTCACATGGCGGTGCACGTCGCCCAGATGACCGGTACTGCCCAGATGCACGCCCTTTTTGA
CGCCGTCACCGTGGGCGCCGCCCGGGTGCTGGAACTGGCGGACTACGGCCTTGTCCCCGGTTGCCATGCCGATATGGTCA
TCCTGCAGGCGCGCGATCCGATCGAAGCGATCCGCCTCAGGCCGGCGCGGCTATGGGTGATCCGCCGCGGCCGGGTGATC
GCCCGTACCGAACCTGTCCTCCCGCAGACAGCGCTCGATGGCTTGTGGCAACCCGTCGATTTTGGGCTTCCCGAAGCGTC
CGCTTAA

Upstream 100 bases:

>100_bases
AGAAGGCGCCGCTACCCCCGCCGGTAACGAGCTGCGGCCCACCCTGGCCCAGTGGCGCACCGAGAGGGTATAACGCTCGG
TCAGTGGAGCGAGCTTGCCA

Downstream 100 bases:

>100_bases
AAGCAATGGCGTGACCAAACACGATCCCAACCGGGCCTTCCCAAAGCACAACGGGTGCCGGAGATCACTCTTCGGCACCC
GTTGCAACGATTGCCTTCCA

Product: cytosine deaminase

Products: NA

Alternate protein names: Cytosine aminohydrolase [H]

Number of amino acids: Translated: 428; Mature: 428

Protein sequence:

>428_residues
MLDLIIRGGNLPDGSGPVDIAVADGRIAAIAPRLEAEAREQIDAHGRLVSPPFIDSHFHIDSTLTFGRPRVNASGTLLEG
IALWGELRPQLTFEEIKGRALGFCRWAIARGNLAVRSHVDVCDPTLTAVQALLEVRAQIKPYLDLQLVAFPQQGYLRYRE
APGLLERALDLGVEVVGGIPHFERTAAEGALSVRKLCELAAERGLPVDMHCDESDDPHSRFVENLACETERLGLQGRVTG
SHLTSLHSMDNYYAGKLIDLMAEARLNVVANPLINITLQGRHDTYPKRRGLTRIREQMAAGLTVALGHDCVLDPWYPLGS
HDMLEVVHMAVHVAQMTGTAQMHALFDAVTVGAARVLELADYGLVPGCHADMVILQARDPIEAIRLRPARLWVIRRGRVI
ARTEPVLPQTALDGLWQPVDFGLPEASA

Sequences:

>Translated_428_residues
MLDLIIRGGNLPDGSGPVDIAVADGRIAAIAPRLEAEAREQIDAHGRLVSPPFIDSHFHIDSTLTFGRPRVNASGTLLEG
IALWGELRPQLTFEEIKGRALGFCRWAIARGNLAVRSHVDVCDPTLTAVQALLEVRAQIKPYLDLQLVAFPQQGYLRYRE
APGLLERALDLGVEVVGGIPHFERTAAEGALSVRKLCELAAERGLPVDMHCDESDDPHSRFVENLACETERLGLQGRVTG
SHLTSLHSMDNYYAGKLIDLMAEARLNVVANPLINITLQGRHDTYPKRRGLTRIREQMAAGLTVALGHDCVLDPWYPLGS
HDMLEVVHMAVHVAQMTGTAQMHALFDAVTVGAARVLELADYGLVPGCHADMVILQARDPIEAIRLRPARLWVIRRGRVI
ARTEPVLPQTALDGLWQPVDFGLPEASA
>Mature_428_residues
MLDLIIRGGNLPDGSGPVDIAVADGRIAAIAPRLEAEAREQIDAHGRLVSPPFIDSHFHIDSTLTFGRPRVNASGTLLEG
IALWGELRPQLTFEEIKGRALGFCRWAIARGNLAVRSHVDVCDPTLTAVQALLEVRAQIKPYLDLQLVAFPQQGYLRYRE
APGLLERALDLGVEVVGGIPHFERTAAEGALSVRKLCELAAERGLPVDMHCDESDDPHSRFVENLACETERLGLQGRVTG
SHLTSLHSMDNYYAGKLIDLMAEARLNVVANPLINITLQGRHDTYPKRRGLTRIREQMAAGLTVALGHDCVLDPWYPLGS
HDMLEVVHMAVHVAQMTGTAQMHALFDAVTVGAARVLELADYGLVPGCHADMVILQARDPIEAIRLRPARLWVIRRGRVI
ARTEPVLPQTALDGLWQPVDFGLPEASA

Specific function: Unknown

COG id: COG0402

COG function: function code FR; Cytosine deaminase and related metal-dependent hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786531, Length=402, Percent_Identity=45.771144278607, Blast_Score=367, Evalue=1e-102,
Organism=Escherichia coli, GI1786517, Length=402, Percent_Identity=25.6218905472637, Blast_Score=87, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013108
- InterPro:   IPR011059 [H]

Pfam domain/function: PF07969 Amidohydro_3 [H]

EC number: =3.5.4.1 [H]

Molecular weight: Translated: 46863; Mature: 46863

Theoretical pI: Translated: 6.20; Mature: 6.20

Prosite motif: PS01137 TATD_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDLIIRGGNLPDGSGPVDIAVADGRIAAIAPRLEAEAREQIDAHGRLVSPPFIDSHFHI
CEEEEEECCCCCCCCCCEEEEEECCEEEEECCHHHHHHHHHHHHCCCCCCCCCCCCCEEE
DSTLTFGRPRVNASGTLLEGIALWGELRPQLTFEEIKGRALGFCRWAIARGNLAVRSHVD
CCEEECCCCCCCCCCHHHHHHHHHHHCCCCEEHHHHCCCHHHHEEEEHHCCCEEEECCCC
VCDPTLTAVQALLEVRAQIKPYLDLQLVAFPQQGYLRYREAPGLLERALDLGVEVVGGIP
CCCHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCEEECCCCHHHHHHHHCCHHEECCCC
HFERTAAEGALSVRKLCELAAERGLPVDMHCDESDDPHSRFVENLACETERLGLQGRVTG
CHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHHHHCCCCEEECH
SHLTSLHSMDNYYAGKLIDLMAEARLNVVANPLINITLQGRHDTYPKRRGLTRIREQMAA
HHHHHHHHHCCHHHHHHHHHHHHHHHHHEECCEEEEEECCCCCCCHHHHHHHHHHHHHHC
GLTVALGHDCVLDPWYPLGSHDMLEVVHMAVHVAQMTGTAQMHALFDAVTVGAARVLELA
CEEEEECCCEEECCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
DYGLVPGCHADMVILQARDPIEAIRLRPARLWVIRRGRVIARTEPVLPQTALDGLWQPVD
HCCCCCCCCCCEEEEECCCCHHHHHCCHHEEEEEECCEEEEECCCCCCHHHHHHCCCCCC
FGLPEASA
CCCCCCCC
>Mature Secondary Structure
MLDLIIRGGNLPDGSGPVDIAVADGRIAAIAPRLEAEAREQIDAHGRLVSPPFIDSHFHI
CEEEEEECCCCCCCCCCEEEEEECCEEEEECCHHHHHHHHHHHHCCCCCCCCCCCCCEEE
DSTLTFGRPRVNASGTLLEGIALWGELRPQLTFEEIKGRALGFCRWAIARGNLAVRSHVD
CCEEECCCCCCCCCCHHHHHHHHHHHCCCCEEHHHHCCCHHHHEEEEHHCCCEEEECCCC
VCDPTLTAVQALLEVRAQIKPYLDLQLVAFPQQGYLRYREAPGLLERALDLGVEVVGGIP
CCCHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCEEECCCCHHHHHHHHCCHHEECCCC
HFERTAAEGALSVRKLCELAAERGLPVDMHCDESDDPHSRFVENLACETERLGLQGRVTG
CHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHHHHCCCCEEECH
SHLTSLHSMDNYYAGKLIDLMAEARLNVVANPLINITLQGRHDTYPKRRGLTRIREQMAA
HHHHHHHHHCCHHHHHHHHHHHHHHHHHEECCEEEEEECCCCCCCHHHHHHHHHHHHHHC
GLTVALGHDCVLDPWYPLGSHDMLEVVHMAVHVAQMTGTAQMHALFDAVTVGAARVLELA
CEEEEECCCEEECCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
DYGLVPGCHADMVILQARDPIEAIRLRPARLWVIRRGRVIARTEPVLPQTALDGLWQPVD
HCCCCCCCCCCEEEEECCCCHHHHHCCHHEEEEEECCEEEEECCCCCCHHHHHHCCCCCC
FGLPEASA
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1640834; 8450832; 9278503 [H]