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The map label for this gene is fabF [H]

Identifier: 37522089

GI number: 37522089

Start: 2677694

End: 2678797

Strand: Reverse

Name: fabF [H]

Synonym: gll2520

Alternate gene names: 37522089

Gene position: 2678797-2677694 (Counterclockwise)

Preceding gene: 37522091

Following gene: 37522088

Centisome position: 57.5

GC content: 69.57

Gene sequence:

>1104_bases
ATGCTTGCTCTGGAACGTTCCGTGGTGATCACCGGTCTGGGGATCGTTTCTTGTCTGGGAGGCGAGGCGCGCACCACCTG
GAAGCGACTGCTGGCGGGCGAGCGCGGCTATGAACCTGGCGAGCCGGTTGGCCGTGCCGGGACTGTGCAGGCCGAGACGG
GTCGGGTTGTGGCCTTGGTACAGCAGGCTGCCCGCGAAGCACTCGCCGATGCGGGCAGCCGTGAGGCGTTCGATTTTGGG
GTCGCCATCGGCTCCAGTCGTGGACTGCAGGCAGATTGGGAAAACGGTCGCACCGGCCCCTTGATTGGCCTCGACGCCCC
GGCGCACGCCGTGGCGGCCCTGGCAGGTACGCAAGGCCCCCTCGCGGCGCTCTCATGCGCCTGCGCCTCGGGGGCCTGGG
CGATCGGCACAGGCTACCGCTGGATCCGTTGGGGCCTGTGCGATCGGGTGCTCGTGGGCGCCGCCGACGCCGCCATCACC
CCGCTCAACCTAGCGGGTTTTCGTCGGGCCGGTGCTCTGGCCCGCGACGCCTGTCTGCCCTTCGACCGGTGTCATAGCGG
CTTTGTGCTCGCCGAGGGAGCGTCGGTACTCGTACTCGAAGCTGAAGAAGTCGCCCACGGACGGCCCTACACCCGCATCC
GGGGTTTTTCCGCCACCTGCGACGCCTTTCACCCCACCGCCCCGCACCCCGAGGGCGAAGGGCTCGCGCGCGCCGTCGAG
CGCTGCAGAAAGCAAGCTCCGGGGCTGAGCGTGGGGGCTGTCCACGCCCACGGCACCGGCACGGCGGCGGGCGACCCTGT
CGAAGCCGCCGTGATCGCCCGGCTCTACGCCCCTGGTACACCGGTCATCGCCTGCAAGGGGAGTCTCGGCCACAGCCTGG
GAGCAAGCAGCGCCATGGAGGCGGCCCTCGCCTGCCTGGCATTGCAAACTGGGCAGTTGCCCCCGATCGCCGGGCTCACC
GACCCGCTCGCCCCGCTGGCCTTTGTACGCGAAGCCTTCCGGACCTCCGTGACCACCCTCATGCTCCACAGCCTCGGCTT
CGGCGGCCAGAACACGGCACTTCTGCTGGAAGCTTGCCCTTCACCACGCCGCACGTTAGGCTAG

Upstream 100 bases:

>100_bases
GAACCGGCGTCGCCTGGCATGCCAGGATAAGAGCAAACAAAGACCACCACTTGCTTTGCATCGATCCGTCCACTCCGAAC
GTTTATTGACGTATTCTGGC

Downstream 100 bases:

>100_bases
GAAAGCGAAAAGCCCGGGACGTAGCGCAGCTTGGTAGCGCACTACTTTGGGGTAGTAGGGGTCGTGGGTTCAAATCCCGC
CGTCCCGATATTTTAAAACC

Product: 3-oxoacyl-[acyl-carrier-protein] synthase

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase II; Beta-ketoacyl-ACP synthase II; KAS II [H]

Number of amino acids: Translated: 367; Mature: 367

Protein sequence:

>367_residues
MLALERSVVITGLGIVSCLGGEARTTWKRLLAGERGYEPGEPVGRAGTVQAETGRVVALVQQAAREALADAGSREAFDFG
VAIGSSRGLQADWENGRTGPLIGLDAPAHAVAALAGTQGPLAALSCACASGAWAIGTGYRWIRWGLCDRVLVGAADAAIT
PLNLAGFRRAGALARDACLPFDRCHSGFVLAEGASVLVLEAEEVAHGRPYTRIRGFSATCDAFHPTAPHPEGEGLARAVE
RCRKQAPGLSVGAVHAHGTGTAAGDPVEAAVIARLYAPGTPVIACKGSLGHSLGASSAMEAALACLALQTGQLPPIAGLT
DPLAPLAFVREAFRTSVTTLMLHSLGFGGQNTALLLEACPSPRRTLG

Sequences:

>Translated_367_residues
MLALERSVVITGLGIVSCLGGEARTTWKRLLAGERGYEPGEPVGRAGTVQAETGRVVALVQQAAREALADAGSREAFDFG
VAIGSSRGLQADWENGRTGPLIGLDAPAHAVAALAGTQGPLAALSCACASGAWAIGTGYRWIRWGLCDRVLVGAADAAIT
PLNLAGFRRAGALARDACLPFDRCHSGFVLAEGASVLVLEAEEVAHGRPYTRIRGFSATCDAFHPTAPHPEGEGLARAVE
RCRKQAPGLSVGAVHAHGTGTAAGDPVEAAVIARLYAPGTPVIACKGSLGHSLGASSAMEAALACLALQTGQLPPIAGLT
DPLAPLAFVREAFRTSVTTLMLHSLGFGGQNTALLLEACPSPRRTLG
>Mature_367_residues
MLALERSVVITGLGIVSCLGGEARTTWKRLLAGERGYEPGEPVGRAGTVQAETGRVVALVQQAAREALADAGSREAFDFG
VAIGSSRGLQADWENGRTGPLIGLDAPAHAVAALAGTQGPLAALSCACASGAWAIGTGYRWIRWGLCDRVLVGAADAAIT
PLNLAGFRRAGALARDACLPFDRCHSGFVLAEGASVLVLEAEEVAHGRPYTRIRGFSATCDAFHPTAPHPEGEGLARAVE
RCRKQAPGLSVGAVHAHGTGTAAGDPVEAAVIARLYAPGTPVIACKGSLGHSLGASSAMEAALACLALQTGQLPPIAGLT
DPLAPLAFVREAFRTSVTTLMLHSLGFGGQNTALLLEACPSPRRTLG

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP [H]

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-ketoacyl-ACP synthases family [H]

Homologues:

Organism=Homo sapiens, GI8923559, Length=420, Percent_Identity=32.3809523809524, Blast_Score=155, Evalue=8e-38,
Organism=Homo sapiens, GI41872631, Length=266, Percent_Identity=28.1954887218045, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI223972627, Length=153, Percent_Identity=36.6013071895425, Blast_Score=70, Evalue=4e-12,
Organism=Escherichia coli, GI1787337, Length=414, Percent_Identity=29.951690821256, Blast_Score=138, Evalue=5e-34,
Organism=Escherichia coli, GI1788663, Length=413, Percent_Identity=30.9927360774818, Blast_Score=110, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI71983541, Length=399, Percent_Identity=30.3258145363409, Blast_Score=133, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI71983535, Length=258, Percent_Identity=32.9457364341085, Blast_Score=123, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI212642053, Length=331, Percent_Identity=27.4924471299094, Blast_Score=96, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17550940, Length=263, Percent_Identity=25.0950570342205, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6320904, Length=437, Percent_Identity=28.8329519450801, Blast_Score=144, Evalue=3e-35,
Organism=Drosophila melanogaster, GI24644341, Length=412, Percent_Identity=32.5242718446602, Blast_Score=144, Evalue=8e-35,
Organism=Drosophila melanogaster, GI221330659, Length=265, Percent_Identity=29.0566037735849, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI19920632, Length=265, Percent_Identity=29.0566037735849, Blast_Score=92, Evalue=7e-19,
Organism=Drosophila melanogaster, GI24581345, Length=269, Percent_Identity=26.0223048327138, Blast_Score=78, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017568
- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C [H]

EC number: =2.3.1.179 [H]

Molecular weight: Translated: 37518; Mature: 37518

Theoretical pI: Translated: 7.43; Mature: 7.43

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLALERSVVITGLGIVSCLGGEARTTWKRLLAGERGYEPGEPVGRAGTVQAETGRVVALV
CCCCCCEEEEEHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCHHHHHH
QQAAREALADAGSREAFDFGVAIGSSRGLQADWENGRTGPLIGLDAPAHAVAALAGTQGP
HHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCEEECCCCHHHHHHHHCCCCH
LAALSCACASGAWAIGTGYRWIRWGLCDRVLVGAADAAITPLNLAGFRRAGALARDACLP
HHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHCCCCHHCCCCCHHHHHHHCHHHHHHCCC
FDRCHSGFVLAEGASVLVLEAEEVAHGRPYTRIRGFSATCDAFHPTAPHPEGEGLARAVE
HHHCCCCEEEECCCEEEEEEHHHHHCCCCCCEECCCCCCCCCCCCCCCCCCCCHHHHHHH
RCRKQAPGLSVGAVHAHGTGTAAGDPVEAAVIARLYAPGTPVIACKGSLGHSLGASSAME
HHHHHCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCEEEECCCCCCCCCCHHHHH
AALACLALQTGQLPPIAGLTDPLAPLAFVREAFRTSVTTLMLHSLGFGGQNTALLLEACP
HHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCC
SPRRTLG
CCHHCCC
>Mature Secondary Structure
MLALERSVVITGLGIVSCLGGEARTTWKRLLAGERGYEPGEPVGRAGTVQAETGRVVALV
CCCCCCEEEEEHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCHHHHHH
QQAAREALADAGSREAFDFGVAIGSSRGLQADWENGRTGPLIGLDAPAHAVAALAGTQGP
HHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCEEECCCCHHHHHHHHCCCCH
LAALSCACASGAWAIGTGYRWIRWGLCDRVLVGAADAAITPLNLAGFRRAGALARDACLP
HHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHCCCCHHCCCCCHHHHHHHCHHHHHHCCC
FDRCHSGFVLAEGASVLVLEAEEVAHGRPYTRIRGFSATCDAFHPTAPHPEGEGLARAVE
HHHCCCCEEEECCCEEEEEEHHHHHCCCCCCEECCCCCCCCCCCCCCCCCCCCHHHHHHH
RCRKQAPGLSVGAVHAHGTGTAAGDPVEAAVIARLYAPGTPVIACKGSLGHSLGASSAME
HHHHHCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCEEEECCCCCCCCCCHHHHH
AALACLALQTGQLPPIAGLTDPLAPLAFVREAFRTSVTTLMLHSLGFGGQNTALLLEACP
HHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCC
SPRRTLG
CCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA