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The map label for this gene is 37521960

Identifier: 37521960

GI number: 37521960

Start: 2552069

End: 2553292

Strand: Direct

Name: 37521960

Synonym: glr2391

Alternate gene names: NA

Gene position: 2552069-2553292 (Clockwise)

Preceding gene: 37521959

Following gene: 37521961

Centisome position: 54.78

GC content: 60.13

Gene sequence:

>1224_bases
ATGACTGACCGTCGCTATGATGTCGTACTTTACGGAGCTACCGGCTTCGTCGGCCAACAGACAGCACAGTACTTTACTCG
ACACACTCGCCCCGGTGCGGTCCATTGGGCAATCGCGGGCCGGAATCGACAAAAACTCGAATCGCTCAAGGCTCAGCTTG
GCACCAATGTGGATGTCCTGATTGCTGACAGCACCGACCAGCCTGCCCTCGATGCCGTCGCAGCCCAGACCCGCGTCATT
TTAAACACAGCAGGGCCTTTTGCCCTCTACGGAGACGCCATCGTCGATGCTTGCGTCCGGTTGCGAACGCATTATGTCGA
TATCACCGGCGAAACCCCCTGGGTGAGAGATCTTATCGACCGCTATCACGAGCGGGCCGCATCGGAGGGAACTCGGATCA
TTCCTTGCTGCGGGTTCGATTCAGTGCCGTCGGATCTGGGCAGTTACCTGATGGTTCGGCACCTGCAACGAGAATGGGGA
GTGTCCTGCCGGGCGGTGAAGGCCTATTTTCAGATGTACGGCGGCTTGAACGGCGGCACCCTCGCTTCTGGACTGAATTT
GTACGATTCCGGGCGGGCGGCCCGGGTGAGCGATCTCTTTCTGCTGGATCCGCCGGGTGAACATTCCAGCACGGAATTGG
AGCGCAATCGGGACCCGGAGGCCCCCGAGTACGATGCCGGTGTGGATACCTGGGTTGGACCGTTCTTCATGGGCCTGGTG
AACACCCGCGTCGTGCGCCGCAGCCGTGCCCTCTATGACCAGTGGCAAGAGCCTTACGGTCCGCAATTCGTCTACCAGGA
ATATCTCAAGTTCGATCCACCGCTGGCGTGGCTACAGGCCACGGTTGTCACCGTCGGCACGGCCTTGTTTGCAGGAATTA
TGCAACAAGCCCCGCTGCGGCCGTTACTGCAATCGCTGCTTCCCGAGCCCGGCAGTGGTCCCTCCGAGCAGACGATGAAC
GAGGGTTGGTTCCGCTGTGAACTTTTGGGAGTCGCTGAGGACGGGCGCCGGGTGAAGGGACTGATCTGTGACCAGGGAGA
TCCAGGCAACCGCGCCACGGTCAAATTCCTGTGCGAGTCGGCTCTGAGCTTGGTCTTGAACACCGATGAGTTGCCGGGTG
GACAACAGCGAGGCGGTGTCCTGACACCTGCAACCGGGCTTGGAGAAGTGCTGGCAGAACGGCTGCGCAGCGCAGGGATG
ACCCTGAAGGTTGGTGTCGTTTAG

Upstream 100 bases:

>100_bases
CCTTGCGGTCATACAGTGATACCTGCCACCCACAAAACTGAAAAAATACGAACCGACAATCGGTCTAACGCGCTTTTGGT
GATGCAGGAAAATAAGTACC

Downstream 100 bases:

>100_bases
GGGGCCATCCATTTTGGGGGGTGCCTGCGGTATTCCTACGGCATGGGCAGGATAAGAACCCCAACAATTCGGTAATTCGA
CGTCTATCCCGATTGGCGGG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 407; Mature: 406

Protein sequence:

>407_residues
MTDRRYDVVLYGATGFVGQQTAQYFTRHTRPGAVHWAIAGRNRQKLESLKAQLGTNVDVLIADSTDQPALDAVAAQTRVI
LNTAGPFALYGDAIVDACVRLRTHYVDITGETPWVRDLIDRYHERAASEGTRIIPCCGFDSVPSDLGSYLMVRHLQREWG
VSCRAVKAYFQMYGGLNGGTLASGLNLYDSGRAARVSDLFLLDPPGEHSSTELERNRDPEAPEYDAGVDTWVGPFFMGLV
NTRVVRRSRALYDQWQEPYGPQFVYQEYLKFDPPLAWLQATVVTVGTALFAGIMQQAPLRPLLQSLLPEPGSGPSEQTMN
EGWFRCELLGVAEDGRRVKGLICDQGDPGNRATVKFLCESALSLVLNTDELPGGQQRGGVLTPATGLGEVLAERLRSAGM
TLKVGVV

Sequences:

>Translated_407_residues
MTDRRYDVVLYGATGFVGQQTAQYFTRHTRPGAVHWAIAGRNRQKLESLKAQLGTNVDVLIADSTDQPALDAVAAQTRVI
LNTAGPFALYGDAIVDACVRLRTHYVDITGETPWVRDLIDRYHERAASEGTRIIPCCGFDSVPSDLGSYLMVRHLQREWG
VSCRAVKAYFQMYGGLNGGTLASGLNLYDSGRAARVSDLFLLDPPGEHSSTELERNRDPEAPEYDAGVDTWVGPFFMGLV
NTRVVRRSRALYDQWQEPYGPQFVYQEYLKFDPPLAWLQATVVTVGTALFAGIMQQAPLRPLLQSLLPEPGSGPSEQTMN
EGWFRCELLGVAEDGRRVKGLICDQGDPGNRATVKFLCESALSLVLNTDELPGGQQRGGVLTPATGLGEVLAERLRSAGM
TLKVGVV
>Mature_406_residues
TDRRYDVVLYGATGFVGQQTAQYFTRHTRPGAVHWAIAGRNRQKLESLKAQLGTNVDVLIADSTDQPALDAVAAQTRVIL
NTAGPFALYGDAIVDACVRLRTHYVDITGETPWVRDLIDRYHERAASEGTRIIPCCGFDSVPSDLGSYLMVRHLQREWGV
SCRAVKAYFQMYGGLNGGTLASGLNLYDSGRAARVSDLFLLDPPGEHSSTELERNRDPEAPEYDAGVDTWVGPFFMGLVN
TRVVRRSRALYDQWQEPYGPQFVYQEYLKFDPPLAWLQATVVTVGTALFAGIMQQAPLRPLLQSLLPEPGSGPSEQTMNE
GWFRCELLGVAEDGRRVKGLICDQGDPGNRATVKFLCESALSLVLNTDELPGGQQRGGVLTPATGLGEVLAERLRSAGMT
LKVGVV

Specific function: Unknown

COG id: COG3268

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the saccharopine dehydrogenase family. Enoyl reductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI55770836, Length=443, Percent_Identity=25.5079006772009, Blast_Score=126, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17560066, Length=431, Percent_Identity=26.9141531322506, Blast_Score=137, Evalue=7e-33,
Organism=Caenorhabditis elegans, GI32567112, Length=398, Percent_Identity=26.6331658291457, Blast_Score=130, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI71991033, Length=420, Percent_Identity=27.3809523809524, Blast_Score=122, Evalue=5e-28,
Organism=Drosophila melanogaster, GI24644140, Length=447, Percent_Identity=28.6353467561521, Blast_Score=144, Evalue=8e-35,
Organism=Drosophila melanogaster, GI24644142, Length=447, Percent_Identity=28.6353467561521, Blast_Score=144, Evalue=8e-35,
Organism=Drosophila melanogaster, GI21356081, Length=447, Percent_Identity=28.6353467561521, Blast_Score=144, Evalue=8e-35,
Organism=Drosophila melanogaster, GI24646278, Length=453, Percent_Identity=26.4900662251656, Blast_Score=138, Evalue=7e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR005097 [H]

Pfam domain/function: PF03435 Saccharop_dh [H]

EC number: NA

Molecular weight: Translated: 44627; Mature: 44496

Theoretical pI: Translated: 5.47; Mature: 5.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDRRYDVVLYGATGFVGQQTAQYFTRHTRPGAVHWAIAGRNRQKLESLKAQLGTNVDVL
CCCCEEEEEEECCCCCCHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHCCCEEEE
IADSTDQPALDAVAAQTRVILNTAGPFALYGDAIVDACVRLRTHYVDITGETPWVRDLID
EECCCCCCHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHH
RYHERAASEGTRIIPCCGFDSVPSDLGSYLMVRHLQREWGVSCRAVKAYFQMYGGLNGGT
HHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCH
LASGLNLYDSGRAARVSDLFLLDPPGEHSSTELERNRDPEAPEYDAGVDTWVGPFFMGLV
HHCCCCCCCCCCCCEEEEEEEECCCCCCCCCHHHHCCCCCCCCCCCCCHHHHHHHHHHHH
NTRVVRRSRALYDQWQEPYGPQFVYQEYLKFDPPLAWLQATVVTVGTALFAGIMQQAPLR
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHH
PLLQSLLPEPGSGPSEQTMNEGWFRCELLGVAEDGRRVKGLICDQGDPGNRATVKFLCES
HHHHHHCCCCCCCCCHHHHCCCCEEEEEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHH
ALSLVLNTDELPGGQQRGGVLTPATGLGEVLAERLRSAGMTLKVGVV
HHHHHCCCCCCCCCCCCCCEECCCCCHHHHHHHHHHHCCCEEEEECC
>Mature Secondary Structure 
TDRRYDVVLYGATGFVGQQTAQYFTRHTRPGAVHWAIAGRNRQKLESLKAQLGTNVDVL
CCCEEEEEEECCCCCCHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHCCCEEEE
IADSTDQPALDAVAAQTRVILNTAGPFALYGDAIVDACVRLRTHYVDITGETPWVRDLID
EECCCCCCHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHH
RYHERAASEGTRIIPCCGFDSVPSDLGSYLMVRHLQREWGVSCRAVKAYFQMYGGLNGGT
HHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCH
LASGLNLYDSGRAARVSDLFLLDPPGEHSSTELERNRDPEAPEYDAGVDTWVGPFFMGLV
HHCCCCCCCCCCCCEEEEEEEECCCCCCCCCHHHHCCCCCCCCCCCCCHHHHHHHHHHHH
NTRVVRRSRALYDQWQEPYGPQFVYQEYLKFDPPLAWLQATVVTVGTALFAGIMQQAPLR
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHH
PLLQSLLPEPGSGPSEQTMNEGWFRCELLGVAEDGRRVKGLICDQGDPGNRATVKFLCES
HHHHHHCCCCCCCCCHHHHCCCCEEEEEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHH
ALSLVLNTDELPGGQQRGGVLTPATGLGEVLAERLRSAGMTLKVGVV
HHHHHCCCCCCCCCCCCCCEECCCCCHHHHHHHHHHHCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230 [H]