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The map label for this gene is thrC [H]

Identifier: 37521931

GI number: 37521931

Start: 2524335

End: 2525522

Strand: Reverse

Name: thrC [H]

Synonym: gvip326

Alternate gene names: 37521931

Gene position: 2525522-2524335 (Counterclockwise)

Preceding gene: 37521933

Following gene: 37521930

Centisome position: 54.21

GC content: 64.06

Gene sequence:

>1188_bases
ATGTTTGCTTTTATCAGCCATTTGATTTGCCCGCGCTGCGACAGCCGCTTTGATCCGCGCAAAGTCCACAACCTTTGCAC
TGCCTGCGCTTCGCCTTTGTTGGTCGAGTACGACCTCGAACAGGTCCGTGCCTCGGTGGATAAAGAGACGCTCGCCCGCC
GCGGCGAGTCGATGTGGCGCTACCGGGAACTGCTGCCCGTGATGGACCCGGCCCATATCGTGAGCTTCGGCGAAGGGTTC
ACACCACTGCTACCCATCGACGCGCTCACCCGAACCTGGGGATTGGAGACAGTCTGGATCAAAGACGACGGGCTCAATCC
TACCGGCTCCTTCAAGGCGCGGGGTGCCTCCTGCGGCATCTCGAAGGCTAAAGAACTCGGTATCCGGGAGGTGGCCCTGC
CCACGGCGGGCAACGCGGGCGGTGCCTGGGCCTGCTACGGGGCCGCCGCCGGTTTGCGCGTGCACGTGGCGATGCCCAGG
GACGCCCCGGCCGTCAACCAGCTCGAATGCCGTCTGTACGGCGCGGATCTGACATTAGTGGACGGGTTGATTTCGGACGC
GGGAAAATTGATTGCCCAGGGGGTGCGCGAGCATGGCTGGTTCGACGTCTCGACGCTCAAGGAGCCTTACCGCATCGAGG
GCAAGAAGACCCTGGGTCTTGAACTTGCCGAGCAGATGAACTGGCAGTTGCCCGATGCCATCCTCTACCCGGCCGGGGGC
GGCGTCGGAATCATCGGCATCTGGCGGGGCTTGCAGCAATTGAAAGCGATGGGCTGGGTGACGGGAAGTCTGCCCCGGCT
CATTGTCGTGCAGGCAGAAGGCTGCGCTCCGCTGGTCAAGGCGTTCGAGGAGGGCCGCACCGAGTCCGAATTCTGGCCGG
ATGCCCGGACTTTTGCCTCCGGACTGCGCGTACCTAAGGCCCTGGGCGATTTTCTGGTGCTGCAGGCGGTGCGCGAGACC
GGCGGCACCGCCATCGCCGTCAGCGACGAGCAGTGCGGCGAGATGATGAAACTTTTGGCCGGTCGCACCGGGATATTTGC
AGCACCGGAAGGAGCCGCCACCCTGGCTGCCGCCAAAATCCTGCGCGAGCGCGGCGATCTGGCTTCCCGCGATCGGGTGG
TGCTCATCAACACCGGCTCCGCTCTCAAGTACCCGGAGGCAATGAGCGAGGCACTGGCGATGCGGTAG

Upstream 100 bases:

>100_bases
GTACCTTTCTCGCCCACGAATACTGGAACGAAAGTTGTCTATGTTTCCCATGCTATGAAATGAATACCTGTTTTGGCTTC
TGTCCTCTGAAATAGTCGCG

Downstream 100 bases:

>100_bases
CCGGCTACCCTTTACACTTCCAGTTCTTCCAGCACCAGAGGGAAATTGCTCATCAACACCGGCTCCGCCCTCAAGTACCC
GGAGGTGATGACCAAGGCAC

Product: threonine synthase

Products: NA

Alternate protein names: TS [H]

Number of amino acids: Translated: 395; Mature: 395

Protein sequence:

>395_residues
MFAFISHLICPRCDSRFDPRKVHNLCTACASPLLVEYDLEQVRASVDKETLARRGESMWRYRELLPVMDPAHIVSFGEGF
TPLLPIDALTRTWGLETVWIKDDGLNPTGSFKARGASCGISKAKELGIREVALPTAGNAGGAWACYGAAAGLRVHVAMPR
DAPAVNQLECRLYGADLTLVDGLISDAGKLIAQGVREHGWFDVSTLKEPYRIEGKKTLGLELAEQMNWQLPDAILYPAGG
GVGIIGIWRGLQQLKAMGWVTGSLPRLIVVQAEGCAPLVKAFEEGRTESEFWPDARTFASGLRVPKALGDFLVLQAVRET
GGTAIAVSDEQCGEMMKLLAGRTGIFAAPEGAATLAAAKILRERGDLASRDRVVLINTGSALKYPEAMSEALAMR

Sequences:

>Translated_395_residues
MFAFISHLICPRCDSRFDPRKVHNLCTACASPLLVEYDLEQVRASVDKETLARRGESMWRYRELLPVMDPAHIVSFGEGF
TPLLPIDALTRTWGLETVWIKDDGLNPTGSFKARGASCGISKAKELGIREVALPTAGNAGGAWACYGAAAGLRVHVAMPR
DAPAVNQLECRLYGADLTLVDGLISDAGKLIAQGVREHGWFDVSTLKEPYRIEGKKTLGLELAEQMNWQLPDAILYPAGG
GVGIIGIWRGLQQLKAMGWVTGSLPRLIVVQAEGCAPLVKAFEEGRTESEFWPDARTFASGLRVPKALGDFLVLQAVRET
GGTAIAVSDEQCGEMMKLLAGRTGIFAAPEGAATLAAAKILRERGDLASRDRVVLINTGSALKYPEAMSEALAMR
>Mature_395_residues
MFAFISHLICPRCDSRFDPRKVHNLCTACASPLLVEYDLEQVRASVDKETLARRGESMWRYRELLPVMDPAHIVSFGEGF
TPLLPIDALTRTWGLETVWIKDDGLNPTGSFKARGASCGISKAKELGIREVALPTAGNAGGAWACYGAAAGLRVHVAMPR
DAPAVNQLECRLYGADLTLVDGLISDAGKLIAQGVREHGWFDVSTLKEPYRIEGKKTLGLELAEQMNWQLPDAILYPAGG
GVGIIGIWRGLQQLKAMGWVTGSLPRLIVVQAEGCAPLVKAFEEGRTESEFWPDARTFASGLRVPKALGDFLVLQAVRET
GGTAIAVSDEQCGEMMKLLAGRTGIFAAPEGAATLAAAKILRERGDLASRDRVVLINTGSALKYPEAMSEALAMR

Specific function: Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine [H]

COG id: COG0498

COG function: function code E; Threonine synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the threonine synthase family [H]

Homologues:

Organism=Drosophila melanogaster, GI21355833, Length=242, Percent_Identity=31.8181818181818, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: 1344 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR000634
- InterPro:   IPR004450 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.3.1 [H]

Molecular weight: Translated: 42636; Mature: 42636

Theoretical pI: Translated: 6.66; Mature: 6.66

Prosite motif: PS00165 DEHYDRATASE_SER_THR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFAFISHLICPRCDSRFDPRKVHNLCTACASPLLVEYDLEQVRASVDKETLARRGESMWR
CHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCEEEEECHHHHHHHCCHHHHHHHHHHHHH
YRELLPVMDPAHIVSFGEGFTPLLPIDALTRTWGLETVWIKDDGLNPTGSFKARGASCGI
HHHHHCCCCHHHHHHCCCCCCCCCCHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCC
SKAKELGIREVALPTAGNAGGAWACYGAAAGLRVHVAMPRDAPAVNQLECRLYGADLTLV
HHHHHCCCCEEECCCCCCCCCCEEEHHCCCCCEEEEECCCCCCCCCCEEEEEECCCHHHH
DGLISDAGKLIAQGVREHGWFDVSTLKEPYRIEGKKTLGLELAEQMNWQLPDAILYPAGG
HHHHHHHHHHHHHHHHHCCCEEHHHCCCCCEECCCHHHHHHHHHHCCCCCCCEEEECCCC
GVGIIGIWRGLQQLKAMGWVTGSLPRLIVVQAEGCAPLVKAFEEGRTESEFWPDARTFAS
CEEHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHCCCCCCCCCCCHHHHHH
GLRVPKALGDFLVLQAVRETGGTAIAVSDEQCGEMMKLLAGRTGIFAAPEGAATLAAAKI
HCCCHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHH
LRERGDLASRDRVVLINTGSALKYPEAMSEALAMR
HHHHCCCCCCCCEEEEECCCCCCCHHHHHHHHCCC
>Mature Secondary Structure
MFAFISHLICPRCDSRFDPRKVHNLCTACASPLLVEYDLEQVRASVDKETLARRGESMWR
CHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCEEEEECHHHHHHHCCHHHHHHHHHHHHH
YRELLPVMDPAHIVSFGEGFTPLLPIDALTRTWGLETVWIKDDGLNPTGSFKARGASCGI
HHHHHCCCCHHHHHHCCCCCCCCCCHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCC
SKAKELGIREVALPTAGNAGGAWACYGAAAGLRVHVAMPRDAPAVNQLECRLYGADLTLV
HHHHHCCCCEEECCCCCCCCCCEEEHHCCCCCEEEEECCCCCCCCCCEEEEEECCCHHHH
DGLISDAGKLIAQGVREHGWFDVSTLKEPYRIEGKKTLGLELAEQMNWQLPDAILYPAGG
HHHHHHHHHHHHHHHHHCCCEEHHHCCCCCEECCCHHHHHHHHHHCCCCCCCEEEECCCC
GVGIIGIWRGLQQLKAMGWVTGSLPRLIVVQAEGCAPLVKAFEEGRTESEFWPDARTFAS
CEEHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHCCCCCCCCCCCHHHHHH
GLRVPKALGDFLVLQAVRETGGTAIAVSDEQCGEMMKLLAGRTGIFAAPEGAATLAAAKI
HCCCHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHH
LRERGDLASRDRVVLINTGSALKYPEAMSEALAMR
HHHHCCCCCCCCEEEEECCCCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]