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The map label for this gene is ucpA [C]

Identifier: 37521924

GI number: 37521924

Start: 2516538

End: 2517386

Strand: Direct

Name: ucpA [C]

Synonym: glr2355

Alternate gene names: 37521924

Gene position: 2516538-2517386 (Clockwise)

Preceding gene: 37521923

Following gene: 37521927

Centisome position: 54.01

GC content: 67.73

Gene sequence:

>849_bases
ATGGGGCTTTTATCGGGAAGGGTGGCGGTGGTGACGGGGGCAAGCCGGGGAGCAGGCCGCGGAATTGCCCTGGCTTTGGG
CGATACGGGGGCGACGGTCTACGTCACCGGCCGCACGGTGCGCGGCGGATCGCTCCCCTTCATCGGCGCCCCCGGCACGA
TCGAGGATACGGCAGAAGGGGTCACGGCGCGGGGTGGCCGGGGTATCGCCGTGCGCTGCGATCACACCGATGACATCCAG
AGTGCCGCTCTTTTCGAGCGGGTAGCCCACGAGCAGGGCCGCCTGGATCTGCTAGTCAACAACGCCTGGGGCGGCAACGA
GGGGTCTTTCGCCGAGGTGCCTTTTTGGGAAGAACCCCTGACCAACTGGGATTGCATGTTCACCGCCGGGGTACGCGCCC
ATCTGGCCGCCAGCCGCTTTGCGGTGCCTGTGATGCTGAAGGCGGGCTGCGGACTCATCGTTTGTACAACTTTTTATGAC
GAAGGCCGCTTCATCGGCAATCTGTACTACGACCTGGCCAAGGCGAGCATCAACCGCCTGGCCTTCGGTCTGGCCTGCCA
GTTGCGCCCCCACGGCATCGCCGCGGTTGCCCTCTCGCCGGGGTTCATGCGCACCGAACTGGTGCTGATGCACCCGGATC
CGCAGGTGGGCGAGCCGGGCGAATCGACCGAGTACATCGGCCGGGCGGTAGCGGCCCTCGCGGCCGACCCGCACATCCTG
GAGCGCAGCGGCCGGGTGCTGGTGGTGGGCGAATTGGCGCGCGAGTACGGCTTGTGCGACATCGACGGCAGCCAACCTCC
CCCCTTTCGCCTGCCGCCAGGGGCACACCCCCAGCCCCCGCGGCGATGA

Upstream 100 bases:

>100_bases
TCGCGATTTCGAACCGGCACCTACCGAAGAGACACCGCCCGCCCGCAGCAGACCTTCGACCCCTTAGCCTGGAAACGTAG
CGTTTGCACAGGGACTTGCC

Downstream 100 bases:

>100_bases
TCCGGTTTGCAGCGCCCTCTCAGTGCGAACCCCGGCTCCAGATGCCGCTTGCGCGCATTTCGGGGTCGGACGAATCGGCC
CCGTCTTCGAAGGAGAAGGC

Product: oxidoreductase

Products: NA

Alternate protein names: ORFC [H]

Number of amino acids: Translated: 282; Mature: 281

Protein sequence:

>282_residues
MGLLSGRVAVVTGASRGAGRGIALALGDTGATVYVTGRTVRGGSLPFIGAPGTIEDTAEGVTARGGRGIAVRCDHTDDIQ
SAALFERVAHEQGRLDLLVNNAWGGNEGSFAEVPFWEEPLTNWDCMFTAGVRAHLAASRFAVPVMLKAGCGLIVCTTFYD
EGRFIGNLYYDLAKASINRLAFGLACQLRPHGIAAVALSPGFMRTELVLMHPDPQVGEPGESTEYIGRAVAALAADPHIL
ERSGRVLVVGELAREYGLCDIDGSQPPPFRLPPGAHPQPPRR

Sequences:

>Translated_282_residues
MGLLSGRVAVVTGASRGAGRGIALALGDTGATVYVTGRTVRGGSLPFIGAPGTIEDTAEGVTARGGRGIAVRCDHTDDIQ
SAALFERVAHEQGRLDLLVNNAWGGNEGSFAEVPFWEEPLTNWDCMFTAGVRAHLAASRFAVPVMLKAGCGLIVCTTFYD
EGRFIGNLYYDLAKASINRLAFGLACQLRPHGIAAVALSPGFMRTELVLMHPDPQVGEPGESTEYIGRAVAALAADPHIL
ERSGRVLVVGELAREYGLCDIDGSQPPPFRLPPGAHPQPPRR
>Mature_281_residues
GLLSGRVAVVTGASRGAGRGIALALGDTGATVYVTGRTVRGGSLPFIGAPGTIEDTAEGVTARGGRGIAVRCDHTDDIQS
AALFERVAHEQGRLDLLVNNAWGGNEGSFAEVPFWEEPLTNWDCMFTAGVRAHLAASRFAVPVMLKAGCGLIVCTTFYDE
GRFIGNLYYDLAKASINRLAFGLACQLRPHGIAAVALSPGFMRTELVLMHPDPQVGEPGESTEYIGRAVAALAADPHILE
RSGRVLVVGELAREYGLCDIDGSQPPPFRLPPGAHPQPPRR

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI209862901, Length=276, Percent_Identity=40.2173913043478, Blast_Score=179, Evalue=3e-45,
Organism=Homo sapiens, GI19923983, Length=276, Percent_Identity=40.2173913043478, Blast_Score=179, Evalue=3e-45,
Organism=Homo sapiens, GI40254986, Length=283, Percent_Identity=25.4416961130742, Blast_Score=75, Evalue=6e-14,
Organism=Escherichia coli, GI87082100, Length=259, Percent_Identity=28.5714285714286, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788459, Length=203, Percent_Identity=27.5862068965517, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1787905, Length=216, Percent_Identity=25.9259259259259, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1787335, Length=250, Percent_Identity=26.8, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17555612, Length=282, Percent_Identity=39.7163120567376, Blast_Score=192, Evalue=1e-49,
Organism=Caenorhabditis elegans, GI71997099, Length=283, Percent_Identity=36.0424028268551, Blast_Score=174, Evalue=6e-44,
Organism=Caenorhabditis elegans, GI86565303, Length=281, Percent_Identity=33.4519572953737, Blast_Score=140, Evalue=6e-34,
Organism=Caenorhabditis elegans, GI71982365, Length=287, Percent_Identity=26.4808362369338, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17559104, Length=210, Percent_Identity=28.0952380952381, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI193204405, Length=212, Percent_Identity=25.9433962264151, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17562910, Length=222, Percent_Identity=27.027027027027, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17558628, Length=203, Percent_Identity=27.0935960591133, Blast_Score=64, Evalue=7e-11,
Organism=Drosophila melanogaster, GI21357673, Length=265, Percent_Identity=26.0377358490566, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI23397609, Length=278, Percent_Identity=26.2589928057554, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI21357041, Length=248, Percent_Identity=26.2096774193548, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI28571526, Length=252, Percent_Identity=25, Blast_Score=73, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 29786; Mature: 29655

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLLSGRVAVVTGASRGAGRGIALALGDTGATVYVTGRTVRGGSLPFIGAPGTIEDTAEG
CCCCCCCEEEEECCCCCCCCEEEEEECCCCCEEEEEEEEECCCCCCEEECCCCCCHHHCC
VTARGGRGIAVRCDHTDDIQSAALFERVAHEQGRLDLLVNNAWGGNEGSFAEVPFWEEPL
CCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCEEECCCCCCCC
TNWDCMFTAGVRAHLAASRFAVPVMLKAGCGLIVCTTFYDEGRFIGNLYYDLAKASINRL
CCCCEEEECCHHHHHHHHHCCEEEEEECCCCEEEEEEEECCCCEEHHHHHHHHHHHHHHH
AFGLACQLRPHGIAAVALSPGFMRTELVLMHPDPQVGEPGESTEYIGRAVAALAADPHIL
EEEEEEEECCCCEEEEEECCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCHHH
ERSGRVLVVGELAREYGLCDIDGSQPPPFRLPPGAHPQPPRR
HCCCCEEEEEEHHHHCCCEECCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
GLLSGRVAVVTGASRGAGRGIALALGDTGATVYVTGRTVRGGSLPFIGAPGTIEDTAEG
CCCCCCEEEEECCCCCCCCEEEEEECCCCCEEEEEEEEECCCCCCEEECCCCCCHHHCC
VTARGGRGIAVRCDHTDDIQSAALFERVAHEQGRLDLLVNNAWGGNEGSFAEVPFWEEPL
CCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCEEECCCCCCCC
TNWDCMFTAGVRAHLAASRFAVPVMLKAGCGLIVCTTFYDEGRFIGNLYYDLAKASINRL
CCCCEEEECCHHHHHHHHHCCEEEEEECCCCEEEEEEEECCCCEEHHHHHHHHHHHHHHH
AFGLACQLRPHGIAAVALSPGFMRTELVLMHPDPQVGEPGESTEYIGRAVAALAADPHIL
EEEEEEEECCCCEEEEEECCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCHHH
ERSGRVLVVGELAREYGLCDIDGSQPPPFRLPPGAHPQPPRR
HCCCCEEEEEEHHHHCCCEECCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8868443 [H]