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The map label for this gene is 37521889

Identifier: 37521889

GI number: 37521889

Start: 2484328

End: 2485485

Strand: Reverse

Name: 37521889

Synonym: gll2320

Alternate gene names: NA

Gene position: 2485485-2484328 (Counterclockwise)

Preceding gene: 37521894

Following gene: 37521888

Centisome position: 53.35

GC content: 64.59

Gene sequence:

>1158_bases
ATGGACGACAAGTTGTTTTTGATGATTCCCGGTCCGACGCCGATGCCGGAGCGGGCGCTCTTGGCCATGGCCAAAGCTCC
CATCGGTCACCGCAGCGGCGAATTTGCCAAGATCATGGCGGAGGTGTCCGAGAACCTCAAGTGGCTGCACCAGACGGCTT
CTGAGGTGCTGATGCTCTCTTCGAGCGGCACGGGGGCTCTCGAAGCGGCGATCATCAATGCCTGCTCCCCCGGCGATCGG
GTGCTGGTCGGTGCCAACGGCAAATTCGGCGAGCGCTGGGTGGAAGTAGCCCAGGCCTTCGGCCTCGATGTCGAGGTTAT
CTTCGCTCCTTACGGACAACCCCTCTCTACGGACGCCTTCAAAGCCGCCCTCGAAGCGGACACCGACAAGACCATCAAAG
CGGTGGTCGTCACCCACAGCGAGAGTTCGACAGGGGTGATCAACGACTTGGAGACGATCGTGGGTTACATCCGCGCCCAC
GGCGAGGCGCTGTCGATCGTCGATGCGGTGACCAGCCTCGGGGCGACGAGCGTGCCGGTGGACGCCTGGGGGCTCGATTT
TGTCGGCTCCGGCTCGCAAAAAGCTTATATGATCCCGCCGGGACTCGGGTTTTTGGCGGTAAGCGAGCGGGGTTGGGCCG
CCTGCGAGCGCTCGACGATGCCGCGCTACTACTTCGACCTGCGCAAGTACCGCAAGGCCCTCAAGAAAAACAACACTCCC
TTCACCACGCCGGTCAATCTCGTCTTTGCCCTGCAGACGACGCTGCAGATGCTGAGAGCCGAGGGGCTCGACGCGCTGTT
TGCCCGCCACGCCCGCCTGCGCGACGCCACCCGCGCCGCTTTACGCGCTCTGGGGCTGGCGCTGTTCAATCCGGACGACC
ACTCCGCAAGCCCGGCGATTACCGCCGTCGTGCCGCCGGAGGGTATTGCCTGCGACAAGTTGCGCGCCACGCTCAAGAAG
CACTACGACATCGTGATCGCGGGCGGCCAGGGGGAGATGGAAGGGCAGATCGTGCGCATCGGCCATCTAGGCTTCGTGGG
TGAGCGCGACGTGCTTACGGCCATCGCTGCCCTCGAAGGCGCCCTGCGCACCCTGGGCTACGACGGCTTCACCCCGGGAA
GCGGCGTGGCGGCGGCAAGCGCGGTGCTTTTCGGCTAA

Upstream 100 bases:

>100_bases
ACCTCCTCCGCTTGCCACCAAGCCGGGTGTGATAAGAATGTATTCCTGGCTACGGGACAGTTGCTAAAATGCCAGGGTTC
AAAGCAGAGGCGCTTCCGTC

Downstream 100 bases:

>100_bases
ACGCCTCTAGTGGTCAATGACCACGGATGTCCGGTTTAATTTGTGCGTACACTAAAAGTGCCCAGGCAGGCTAATACGGG
GAACTGCCGGTAATGCGCAA

Product: small subunit of soluble hydrogenase

Products: NA

Alternate protein names: Tritium exchange subunit [H]

Number of amino acids: Translated: 385; Mature: 385

Protein sequence:

>385_residues
MDDKLFLMIPGPTPMPERALLAMAKAPIGHRSGEFAKIMAEVSENLKWLHQTASEVLMLSSSGTGALEAAIINACSPGDR
VLVGANGKFGERWVEVAQAFGLDVEVIFAPYGQPLSTDAFKAALEADTDKTIKAVVVTHSESSTGVINDLETIVGYIRAH
GEALSIVDAVTSLGATSVPVDAWGLDFVGSGSQKAYMIPPGLGFLAVSERGWAACERSTMPRYYFDLRKYRKALKKNNTP
FTTPVNLVFALQTTLQMLRAEGLDALFARHARLRDATRAALRALGLALFNPDDHSASPAITAVVPPEGIACDKLRATLKK
HYDIVIAGGQGEMEGQIVRIGHLGFVGERDVLTAIAALEGALRTLGYDGFTPGSGVAAASAVLFG

Sequences:

>Translated_385_residues
MDDKLFLMIPGPTPMPERALLAMAKAPIGHRSGEFAKIMAEVSENLKWLHQTASEVLMLSSSGTGALEAAIINACSPGDR
VLVGANGKFGERWVEVAQAFGLDVEVIFAPYGQPLSTDAFKAALEADTDKTIKAVVVTHSESSTGVINDLETIVGYIRAH
GEALSIVDAVTSLGATSVPVDAWGLDFVGSGSQKAYMIPPGLGFLAVSERGWAACERSTMPRYYFDLRKYRKALKKNNTP
FTTPVNLVFALQTTLQMLRAEGLDALFARHARLRDATRAALRALGLALFNPDDHSASPAITAVVPPEGIACDKLRATLKK
HYDIVIAGGQGEMEGQIVRIGHLGFVGERDVLTAIAALEGALRTLGYDGFTPGSGVAAASAVLFG
>Mature_385_residues
MDDKLFLMIPGPTPMPERALLAMAKAPIGHRSGEFAKIMAEVSENLKWLHQTASEVLMLSSSGTGALEAAIINACSPGDR
VLVGANGKFGERWVEVAQAFGLDVEVIFAPYGQPLSTDAFKAALEADTDKTIKAVVVTHSESSTGVINDLETIVGYIRAH
GEALSIVDAVTSLGATSVPVDAWGLDFVGSGSQKAYMIPPGLGFLAVSERGWAACERSTMPRYYFDLRKYRKALKKNNTP
FTTPVNLVFALQTTLQMLRAEGLDALFARHARLRDATRAALRALGLALFNPDDHSASPAITAVVPPEGIACDKLRATLKK
HYDIVIAGGQGEMEGQIVRIGHLGFVGERDVLTAIAALEGALRTLGYDGFTPGSGVAAASAVLFG

Specific function: Soluble hydrogenase catalyzes both production and consumption of hydrogen from suitable artificial electron donors or acceptors. This subunit catalyzes the tritium-exchange activity [H]

COG id: COG0075

COG function: function code E; Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4557289, Length=371, Percent_Identity=32.0754716981132, Blast_Score=168, Evalue=6e-42,
Organism=Caenorhabditis elegans, GI17536281, Length=348, Percent_Identity=32.7586206896552, Blast_Score=154, Evalue=5e-38,
Organism=Saccharomyces cerevisiae, GI6321079, Length=367, Percent_Identity=29.9727520435967, Blast_Score=117, Evalue=2e-27,
Organism=Drosophila melanogaster, GI17530823, Length=345, Percent_Identity=31.304347826087, Blast_Score=158, Evalue=6e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: 2.6.1.-

Molecular weight: Translated: 40854; Mature: 40854

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDDKLFLMIPGPTPMPERALLAMAKAPIGHRSGEFAKIMAEVSENLKWLHQTASEVLMLS
CCCCEEEEECCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEEE
SSGTGALEAAIINACSPGDRVLVGANGKFGERWVEVAQAFGLDVEVIFAPYGQPLSTDAF
CCCCCHHHHHHEECCCCCCEEEEECCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHH
KAALEADTDKTIKAVVVTHSESSTGVINDLETIVGYIRAHGEALSIVDAVTSLGATSVPV
HHHHHCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCC
DAWGLDFVGSGSQKAYMIPPGLGFLAVSERGWAACERSTMPRYYFDLRKYRKALKKNNTP
CCCCCCEECCCCCEEEECCCCCCEEEECCCCCHHHHHCCCCHHHHHHHHHHHHHHCCCCC
FTTPVNLVFALQTTLQMLRAEGLDALFARHARLRDATRAALRALGLALFNPDDHSASPAI
CCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCEE
TAVVPPEGIACDKLRATLKKHYDIVIAGGQGEMEGQIVRIGHLGFVGERDVLTAIAALEG
EEEECCCCCCHHHHHHHHHHCCEEEEECCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHH
ALRTLGYDGFTPGSGVAAASAVLFG
HHHHCCCCCCCCCCCHHHHHHHHCC
>Mature Secondary Structure
MDDKLFLMIPGPTPMPERALLAMAKAPIGHRSGEFAKIMAEVSENLKWLHQTASEVLMLS
CCCCEEEEECCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEEE
SSGTGALEAAIINACSPGDRVLVGANGKFGERWVEVAQAFGLDVEVIFAPYGQPLSTDAF
CCCCCHHHHHHEECCCCCCEEEEECCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHH
KAALEADTDKTIKAVVVTHSESSTGVINDLETIVGYIRAHGEALSIVDAVTSLGATSVPV
HHHHHCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCC
DAWGLDFVGSGSQKAYMIPPGLGFLAVSERGWAACERSTMPRYYFDLRKYRKALKKNNTP
CCCCCCEECCCCCEEEECCCCCCEEEECCCCCHHHHHCCCCHHHHHHHHHHHHHHCCCCC
FTTPVNLVFALQTTLQMLRAEGLDALFARHARLRDATRAALRALGLALFNPDDHSASPAI
CCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCEE
TAVVPPEGIACDKLRATLKKHYDIVIAGGQGEMEGQIVRIGHLGFVGERDVLTAIAALEG
EEEECCCCCCHHHHHHHHHHCCEEEEECCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHH
ALRTLGYDGFTPGSGVAAASAVLFG
HHHHCCCCCCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2513553 [H]