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The map label for this gene is hslO

Identifier: 37521850

GI number: 37521850

Start: 2443003

End: 2443923

Strand: Direct

Name: hslO

Synonym: gvip309

Alternate gene names: 37521850

Gene position: 2443003-2443923 (Clockwise)

Preceding gene: 37521849

Following gene: 37521852

Centisome position: 52.44

GC content: 64.5

Gene sequence:

>921_bases
ATGGCGGATCAACTGGTACGGGCGACGGCGGCACAGGGCAGGATCCGGGCCGTGGGCGTGCTCTCGACGCGCCTGACGGA
GGAAGCGCGCGGCCGGCACAAGCTCTCGTATGTGGCGACGGCGGCTTTGGGGCGGACGATGGCGGCCGGTTTGCTGATTG
CCTCCAACTTCAAGCAGACCGAGGCGCGGGTGAACCTGCGCCTCCAGGGAGATGGACCCTTGGGCGGCATTCTGGTGGAC
GCGGGGGCCGACGGCACCGTGCGCGGCTACGTCAAAAACCCCCAGGTGGAACTGCCCCCTTCCCCCAAGGGCAAGCTCGA
CGTCGGCCGGGCGGTGGGAGCGAACGGTTTTCTCTATGTGGTCAAAGATCTGGGCTATGGCTACCCGTTTTCGGGCACGA
CCGAACTGGTGAGCGGCGAAATCGGCGACGATGTCACCCATTACCTGGTCACCTCCGAGCAGGTGGCCTCGGCCCTGATG
CTCGGGGTGTTCGTGGGCGCCGACGGGGTGGATGCGGCCGGCGGGCTGCTGTTGCAGGTGATGCCCAGTGCCGATGGCCA
GGAGGACGAGGAACTGGCCGCTACGCTTGAGAGGCGACTGGCGAGTGTAGAAGGTTTTACGCCCCTGGTGCGCTCGGGCA
AGCGCATCCCCCAGATTCTCGAGGAACTGCTGGGGGATATGGGCCTCGAAATTTTTCCGGAGGTGCAGTTGGTGCGCTTC
CACTGTCACTGCTCGCCGCAGCGGGTCCTGGGGGCACTCAAAATGATGGGCGAAGCCGAACTGCTCGATATGATCGAAAA
AGACGGCGGGGCTGAGGCCACCTGCCACTTCTGCAACCAGGTCTACCAGGTCAAAGCGAGCGAGCTTGAGACCCTGGTCG
AGCAACTGCGCTCCGAGCGCGAGGTCAGTTCGCAAGAATAA

Upstream 100 bases:

>100_bases
GCTCCAATCCTCAGGTGATCGCCGCCTACCTGGGCGGCGCAGTTTAATGCCCCGGCAGGGCACAATAGAGAAAGTGTGTA
AATTTCCGTAAAGGATTTTC

Downstream 100 bases:

>100_bases
AAAAGGGGAGGCCGTCTGCCTCCCCTATCGTTCAATGTTTCGAACGTTTTACGAACGGCCGGTCATCTGCTGCTGCCGGA
TGTCCTGGTAACGGCTTTTG

Product: Hsp33-like chaperonin

Products: NA

Alternate protein names: Heat shock protein 33 homolog; HSP33

Number of amino acids: Translated: 306; Mature: 305

Protein sequence:

>306_residues
MADQLVRATAAQGRIRAVGVLSTRLTEEARGRHKLSYVATAALGRTMAAGLLIASNFKQTEARVNLRLQGDGPLGGILVD
AGADGTVRGYVKNPQVELPPSPKGKLDVGRAVGANGFLYVVKDLGYGYPFSGTTELVSGEIGDDVTHYLVTSEQVASALM
LGVFVGADGVDAAGGLLLQVMPSADGQEDEELAATLERRLASVEGFTPLVRSGKRIPQILEELLGDMGLEIFPEVQLVRF
HCHCSPQRVLGALKMMGEAELLDMIEKDGGAEATCHFCNQVYQVKASELETLVEQLRSEREVSSQE

Sequences:

>Translated_306_residues
MADQLVRATAAQGRIRAVGVLSTRLTEEARGRHKLSYVATAALGRTMAAGLLIASNFKQTEARVNLRLQGDGPLGGILVD
AGADGTVRGYVKNPQVELPPSPKGKLDVGRAVGANGFLYVVKDLGYGYPFSGTTELVSGEIGDDVTHYLVTSEQVASALM
LGVFVGADGVDAAGGLLLQVMPSADGQEDEELAATLERRLASVEGFTPLVRSGKRIPQILEELLGDMGLEIFPEVQLVRF
HCHCSPQRVLGALKMMGEAELLDMIEKDGGAEATCHFCNQVYQVKASELETLVEQLRSEREVSSQE
>Mature_305_residues
ADQLVRATAAQGRIRAVGVLSTRLTEEARGRHKLSYVATAALGRTMAAGLLIASNFKQTEARVNLRLQGDGPLGGILVDA
GADGTVRGYVKNPQVELPPSPKGKLDVGRAVGANGFLYVVKDLGYGYPFSGTTELVSGEIGDDVTHYLVTSEQVASALML
GVFVGADGVDAAGGLLLQVMPSADGQEDEELAATLERRLASVEGFTPLVRSGKRIPQILEELLGDMGLEIFPEVQLVRFH
CHCSPQRVLGALKMMGEAELLDMIEKDGGAEATCHFCNQVYQVKASELETLVEQLRSEREVSSQE

Specific function: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress

COG id: COG1281

COG function: function code O; Disulfide bond chaperones of the HSP33 family

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HSP33 family

Homologues:

Organism=Escherichia coli, GI87082260, Length=290, Percent_Identity=25.8620689655172, Blast_Score=87, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HSLO_GLOVI (Q7NIA2)

Other databases:

- EMBL:   BA000045
- RefSeq:   NP_925227.1
- ProteinModelPortal:   Q7NIA2
- SMR:   Q7NIA2
- GeneID:   2600683
- GenomeReviews:   BA000045_GR
- NMPDR:   fig|251221.1.peg.2281
- HOGENOM:   HBG286231
- OMA:   QRHKLSY
- ProtClustDB:   PRK00114
- BioCyc:   GVIO251221:GLR2281-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00117
- InterPro:   IPR000397
- InterPro:   IPR016154
- InterPro:   IPR016153
- Gene3D:   G3DSA:3.90.1280.10
- Gene3D:   G3DSA:3.55.30.10
- PIRSF:   PIRSF005261

Pfam domain/function: PF01430 HSP33; SSF64397 Heat_shock_Hsp33_N

EC number: NA

Molecular weight: Translated: 32669; Mature: 32538

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADQLVRATAAQGRIRAVGVLSTRLTEEARGRHKLSYVATAALGRTMAAGLLIASNFKQT
CCCHHHHHHHHCCCEEEEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHC
EARVNLRLQGDGPLGGILVDAGADGTVRGYVKNPQVELPPSPKGKLDVGRAVGANGFLYV
CEEEEEEEECCCCCCCEEEECCCCCCEEEEEECCEEECCCCCCCCCCCCCCCCCCCEEEE
VKDLGYGYPFSGTTELVSGEIGDDVTHYLVTSEQVASALMLGVFVGADGVDAAGGLLLQV
EECCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEE
MPSADGQEDEELAATLERRLASVEGFTPLVRSGKRIPQILEELLGDMGLEIFPEVQLVRF
ECCCCCCCHHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHCCCEECCCEEEEEE
HCHCSPQRVLGALKMMGEAELLDMIEKDGGAEATCHFCNQVYQVKASELETLVEQLRSER
EECCCHHHHHHHHHHHCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EVSSQE
CCCCCC
>Mature Secondary Structure 
ADQLVRATAAQGRIRAVGVLSTRLTEEARGRHKLSYVATAALGRTMAAGLLIASNFKQT
CCHHHHHHHHCCCEEEEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHC
EARVNLRLQGDGPLGGILVDAGADGTVRGYVKNPQVELPPSPKGKLDVGRAVGANGFLYV
CEEEEEEEECCCCCCCEEEECCCCCCEEEEEECCEEECCCCCCCCCCCCCCCCCCCEEEE
VKDLGYGYPFSGTTELVSGEIGDDVTHYLVTSEQVASALMLGVFVGADGVDAAGGLLLQV
EECCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEE
MPSADGQEDEELAATLERRLASVEGFTPLVRSGKRIPQILEELLGDMGLEIFPEVQLVRF
ECCCCCCCHHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHCCCEECCCEEEEEE
HCHCSPQRVLGALKMMGEAELLDMIEKDGGAEATCHFCNQVYQVKASELETLVEQLRSER
EECCCHHHHHHHHHHHCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EVSSQE
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14621292