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The map label for this gene is azoB [H]

Identifier: 37521848

GI number: 37521848

Start: 2441183

End: 2442058

Strand: Direct

Name: azoB [H]

Synonym: glr2279

Alternate gene names: 37521848

Gene position: 2441183-2442058 (Clockwise)

Preceding gene: 37521847

Following gene: 37521849

Centisome position: 52.4

GC content: 55.82

Gene sequence:

>876_bases
GTGGAAAAGTCGAATCAAACTATTCTCGTTACCGGCGCAACCGGTCACCAGGGCGGCGCGGTGTCCCGTCATCTTTTGCA
ACGCAAATTTATGGTTCGCGCTCTGGTGCGCGACGAAAACAAGCCCGCCGCCCAGGCACTCAAACAAGCGGGCGCAGAAC
TCATCGAAGGAGATCTCGACGAGCGCGCTTCACTTGAGCGCGCTCTGCAAGGCGTCTTCGGTGTTTTTTCAGTTCAAAGC
TTCGACGACGGGTTGGACGTCGAAATCCGCCAGGGCAAGGCTCTCGTAGACGCGGCGAAAGCGGTGGGCACCCAGCATTT
CCTCTACAGCTCGGTGGGCAGCGCAGAACGCAAAACCGGCATTCCGCATTTCGACAGCAAGTTTCAAGTCGAAGGATACC
TCCGAGCCAGCGGTTTGCCGTACACGATTTTGCGTCCGGTTTTCTTCATGTACAATTACAGCTCCATGCGCCCGATGATT
GAAACCGGAACGCTCTCCCAGCCGCTCAGCCCCGAGCGGAAATTGCAGCAACTTTCTGAAGACGATTACGGAGAAATGGT
CGCCGAGGTTTTCGAGCGACCCGCAGATTTCTTGAATCGCGAGGAGGAAGTCGCAAGCGTGGATCTGACGATGACGGAAG
TCGCTGCCGCGTTCAGCCGCGTTTTGGGAGAAAACGTCGCCTACCAACAAATTCCTTTTGAAGCGTTCGAACAGCAAGCC
GGTGAGGAAATGACCACGATGTATCGCTGGTTTGAGGAGGTCGGCTACGGAGCGGATTTGGTGAAGTTGAAACGCGATTT
TCCGGAGCCGACCGACTTGGAAGCCTATTTGCGCGACCACGATTGGGCAAAACCCACCGAAAGCGCGTCCGATTAA

Upstream 100 bases:

>100_bases
ACGACAGCAGAGAGTCGCCGTGAGCGCACATCACCTGCTTCACGACCGTCATGCAAACTCGCAACCTTGGTTGGCTAACC
AGTTTACAAAGGAGACATCA

Downstream 100 bases:

>100_bases
TCCTGCCATGTTCTACTTGGGGCAGTTCACTGTTTCAAAATATTTCGCCAACGGTATCGTACCCCGGCCATACCCCAAGG
GTGATAAGGTGTCGGGTGCC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 291; Mature: 291

Protein sequence:

>291_residues
MEKSNQTILVTGATGHQGGAVSRHLLQRKFMVRALVRDENKPAAQALKQAGAELIEGDLDERASLERALQGVFGVFSVQS
FDDGLDVEIRQGKALVDAAKAVGTQHFLYSSVGSAERKTGIPHFDSKFQVEGYLRASGLPYTILRPVFFMYNYSSMRPMI
ETGTLSQPLSPERKLQQLSEDDYGEMVAEVFERPADFLNREEEVASVDLTMTEVAAAFSRVLGENVAYQQIPFEAFEQQA
GEEMTTMYRWFEEVGYGADLVKLKRDFPEPTDLEAYLRDHDWAKPTESASD

Sequences:

>Translated_291_residues
MEKSNQTILVTGATGHQGGAVSRHLLQRKFMVRALVRDENKPAAQALKQAGAELIEGDLDERASLERALQGVFGVFSVQS
FDDGLDVEIRQGKALVDAAKAVGTQHFLYSSVGSAERKTGIPHFDSKFQVEGYLRASGLPYTILRPVFFMYNYSSMRPMI
ETGTLSQPLSPERKLQQLSEDDYGEMVAEVFERPADFLNREEEVASVDLTMTEVAAAFSRVLGENVAYQQIPFEAFEQQA
GEEMTTMYRWFEEVGYGADLVKLKRDFPEPTDLEAYLRDHDWAKPTESASD
>Mature_291_residues
MEKSNQTILVTGATGHQGGAVSRHLLQRKFMVRALVRDENKPAAQALKQAGAELIEGDLDERASLERALQGVFGVFSVQS
FDDGLDVEIRQGKALVDAAKAVGTQHFLYSSVGSAERKTGIPHFDSKFQVEGYLRASGLPYTILRPVFFMYNYSSMRPMI
ETGTLSQPLSPERKLQQLSEDDYGEMVAEVFERPADFLNREEEVASVDLTMTEVAAAFSRVLGENVAYQQIPFEAFEQQA
GEEMTTMYRWFEEVGYGADLVKLKRDFPEPTDLEAYLRDHDWAKPTESASD

Specific function: Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Uses preferentially NADPH rather than NADH as an electron donor for its activity. The enzyme reductively cleaved Orange II and carboxy-Orange II, and can a

COG id: COG0702

COG function: function code MG; Predicted nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NmrA-type oxidoreductase family. Azoreductase type 3 subfamily [H]

Homologues:

Organism=Homo sapiens, GI10190720, Length=261, Percent_Identity=28.735632183908, Blast_Score=106, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR008030 [H]

Pfam domain/function: PF05368 NmrA [H]

EC number: NA

Molecular weight: Translated: 32568; Mature: 32568

Theoretical pI: Translated: 4.50; Mature: 4.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKSNQTILVTGATGHQGGAVSRHLLQRKFMVRALVRDENKPAAQALKQAGAELIEGDLD
CCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCH
ERASLERALQGVFGVFSVQSFDDGLDVEIRQGKALVDAAKAVGTQHFLYSSVGSAERKTG
HHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHCCHHHHCC
IPHFDSKFQVEGYLRASGLPYTILRPVFFMYNYSSMRPMIETGTLSQPLSPERKLQQLSE
CCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCHHHHHHHHCC
DDYGEMVAEVFERPADFLNREEEVASVDLTMTEVAAAFSRVLGENVAYQQIPFEAFEQQA
CCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHH
GEEMTTMYRWFEEVGYGADLVKLKRDFPEPTDLEAYLRDHDWAKPTESASD
HHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MEKSNQTILVTGATGHQGGAVSRHLLQRKFMVRALVRDENKPAAQALKQAGAELIEGDLD
CCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCH
ERASLERALQGVFGVFSVQSFDDGLDVEIRQGKALVDAAKAVGTQHFLYSSVGSAERKTG
HHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHCCHHHHCC
IPHFDSKFQVEGYLRASGLPYTILRPVFFMYNYSSMRPMIETGTLSQPLSPERKLQQLSE
CCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCHHHHHHHHCC
DDYGEMVAEVFERPADFLNREEEVASVDLTMTEVAAAFSRVLGENVAYQQIPFEAFEQQA
CCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHH
GEEMTTMYRWFEEVGYGADLVKLKRDFPEPTDLEAYLRDHDWAKPTESASD
HHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12147495 [H]