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The map label for this gene is nreC [H]

Identifier: 37521779

GI number: 37521779

Start: 2364041

End: 2364715

Strand: Reverse

Name: nreC [H]

Synonym: gll2210

Alternate gene names: 37521779

Gene position: 2364715-2364041 (Counterclockwise)

Preceding gene: 37521780

Following gene: 37521778

Centisome position: 50.76

GC content: 56.0

Gene sequence:

>675_bases
GTGTCTAATGTTGATTCCAGTTCAACCCGAATCTTGATCGTCGACGACCACGCCGTGGTGCGTAGGGGGTTTTGCAGCAT
GCTGCGCTCTGCGGGCAACCTGTTTGCGGTTGAGGAAGCCTGCGAAGGCCAGCTCGCCGTACAGATGTTTCGGCAGTCGA
AGCCGGATCTTGTGTTGCTCGATGCCGCCATGCCCGAACTTGACGGCATCGAGGTCACCCGCCTCATGCACAATATCGAA
CCGGCGGCAAAAATCTTGATTGTCACCGAAATGGAAGAGGACTTTCTGCAGGCTTTCCGTGTCGGTGCGAGCGGCTGCAT
CCTCAAGAATGTCGAAAGCCATGAACTGCTCAATGCCGTAGGATTGGTGCTTTCCGGCTATCTGGTCTTCGGCCGGGCGA
TTACCAAGCTCATTGTCGAGAATTATCACCTGGCGGAAGAAGCCGGCAAGTACAGCAAGCTGGCTATTCACCTGACCGAG
AGAGAACGCGAGATTTTAAGTTTGATCTCGCAGGAGTTTACCAATATCGAGATCGCCGAACGGCTGTTTATCAGTCCCCG
CACGGTCGATTCCCACCGCGCCCGGCTGATGCAGAAGCTCGGCACCCGCAACACCGCCGGGCTGGTGCGCATTGCCATGG
AGTACGGATTGCTCTACGAGTCAAAAGTGGGCTGA

Upstream 100 bases:

>100_bases
TGTTCTAGCACAAGACTTACAGTTTTTCTGCTGTAAGCACTTCTGGTTGCTTTTCTGACAGTCCCATTTCCCTTCCAGTA
AGAAAAAGGCAAGGTGTACA

Downstream 100 bases:

>100_bases
AAGCGCACCCACAGCCCGTGGGCCAACTCCACCCACTTTGAGAACCGATGGGCCTGCACCAGCAGGCCCTTTTTTGGGGC
GACGGGCAACAGCATTATTT

Product: two-component response regulator

Products: NA

Alternate protein names: Nitrogen regulation protein C [H]

Number of amino acids: Translated: 224; Mature: 223

Protein sequence:

>224_residues
MSNVDSSSTRILIVDDHAVVRRGFCSMLRSAGNLFAVEEACEGQLAVQMFRQSKPDLVLLDAAMPELDGIEVTRLMHNIE
PAAKILIVTEMEEDFLQAFRVGASGCILKNVESHELLNAVGLVLSGYLVFGRAITKLIVENYHLAEEAGKYSKLAIHLTE
REREILSLISQEFTNIEIAERLFISPRTVDSHRARLMQKLGTRNTAGLVRIAMEYGLLYESKVG

Sequences:

>Translated_224_residues
MSNVDSSSTRILIVDDHAVVRRGFCSMLRSAGNLFAVEEACEGQLAVQMFRQSKPDLVLLDAAMPELDGIEVTRLMHNIE
PAAKILIVTEMEEDFLQAFRVGASGCILKNVESHELLNAVGLVLSGYLVFGRAITKLIVENYHLAEEAGKYSKLAIHLTE
REREILSLISQEFTNIEIAERLFISPRTVDSHRARLMQKLGTRNTAGLVRIAMEYGLLYESKVG
>Mature_223_residues
SNVDSSSTRILIVDDHAVVRRGFCSMLRSAGNLFAVEEACEGQLAVQMFRQSKPDLVLLDAAMPELDGIEVTRLMHNIEP
AAKILIVTEMEEDFLQAFRVGASGCILKNVESHELLNAVGLVLSGYLVFGRAITKLIVENYHLAEEAGKYSKLAIHLTER
EREILSLISQEFTNIEIAERLFISPRTVDSHRARLMQKLGTRNTAGLVRIAMEYGLLYESKVG

Specific function: Member of the two-component regulatory system nreB/nreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. Phosphorylated nreC binds to a GC-rich palindromic sequence at the promoters of the nitrate (narGHJI) and nit

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788222, Length=210, Percent_Identity=33.3333333333333, Blast_Score=100, Evalue=9e-23,
Organism=Escherichia coli, GI1786747, Length=214, Percent_Identity=26.6355140186916, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1787473, Length=194, Percent_Identity=32.9896907216495, Blast_Score=87, Evalue=8e-19,
Organism=Escherichia coli, GI1788521, Length=202, Percent_Identity=29.2079207920792, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1790102, Length=204, Percent_Identity=31.3725490196078, Blast_Score=77, Evalue=7e-16,
Organism=Escherichia coli, GI1788712, Length=203, Percent_Identity=26.1083743842365, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI1788394, Length=235, Percent_Identity=26.3829787234043, Blast_Score=61, Evalue=5e-11,
Organism=Escherichia coli, GI1788550, Length=115, Percent_Identity=35.6521739130435, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 24949; Mature: 24818

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNVDSSSTRILIVDDHAVVRRGFCSMLRSAGNLFAVEEACEGQLAVQMFRQSKPDLVLL
CCCCCCCCCEEEEECCHHHHHHHHHHHHHHCCCEEEEHHHHCHHHHHHHHHCCCCCEEEE
DAAMPELDGIEVTRLMHNIEPAAKILIVTEMEEDFLQAFRVGASGCILKNVESHELLNAV
ECCCCCCCCHHHHHHHHCCCCHHEEEEEECCHHHHHHHHHCCCCCCEECCCHHHHHHHHH
GLVLSGYLVFGRAITKLIVENYHLAEEAGKYSKLAIHLTEREREILSLISQEFTNIEIAE
HHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCEEEEEEEHHHHHHHHHHHHHHHCCHHHHH
RLFISPRTVDSHRARLMQKLGTRNTAGLVRIAMEYGLLYESKVG
HHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHCCCC
>Mature Secondary Structure 
SNVDSSSTRILIVDDHAVVRRGFCSMLRSAGNLFAVEEACEGQLAVQMFRQSKPDLVLL
CCCCCCCCEEEEECCHHHHHHHHHHHHHHCCCEEEEHHHHCHHHHHHHHHCCCCCEEEE
DAAMPELDGIEVTRLMHNIEPAAKILIVTEMEEDFLQAFRVGASGCILKNVESHELLNAV
ECCCCCCCCHHHHHHHHCCCCHHEEEEEECCHHHHHHHHHCCCCCCEECCCHHHHHHHHH
GLVLSGYLVFGRAITKLIVENYHLAEEAGKYSKLAIHLTEREREILSLISQEFTNIEIAE
HHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCEEEEEEEHHHHHHHHHHHHHHHCCHHHHH
RLFISPRTVDSHRARLMQKLGTRNTAGLVRIAMEYGLLYESKVG
HHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12426351 [H]