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The map label for this gene is rfbC [H]

Identifier: 37521774

GI number: 37521774

Start: 2359359

End: 2359907

Strand: Reverse

Name: rfbC [H]

Synonym: gvip304

Alternate gene names: 37521774

Gene position: 2359907-2359359 (Counterclockwise)

Preceding gene: 37521775

Following gene: 37521773

Centisome position: 50.65

GC content: 64.12

Gene sequence:

>549_bases
ATGCAATTTATCAACACCAAACTCGCCGGGGCCTGGATCATCGAACTGGAGCGGCGCGAGGACGAGCGGGGCTTTTTCGC
CCGCACCTTCTGCGCGCGCGAGTTCGAAGCGCAAGGCCTCGCGGGCACCTTCGCCCAGAGCAATCTGTCGTACAACCATC
GGGCAGGCACCCTGCGCGGCCTGCACTACCAGGTGGCCCCCGCCCTCGAGACCAAGCTTGTCCGCTGCACCCGCGGCGCC
ATTTACGACGTGATTGTCGACCTGCGGCCCGGCTCGCGGACTTACCTGCAGCACATCGGCGTCGAACTGAGCGAAGACAA
CCGCTGGGCGCTGTACGTACCGGGCCTGTTCGCCCACGGCTATCAAGCACTCACCGACGGCGCCGAGGTGCTCTATCAGG
TGGGCGAATTTTATACTCCGGGTTACGAACGGGGATTGCGCTACGACGACCCGGCCCTGGCCATCGATTGGCCGCTGCCG
GTCAGTGTTCTGTCCACCAAAGACAACGGCTGGCCCTTGCTTGCCCCCGCTATGCAGGAGCAGCACTAG

Upstream 100 bases:

>100_bases
ATTGACAACGAGCTTTTTTGGTCCGAGTACGTCAGCACCGAGCAGGACAAAAGCGTACTCGTTCAGCAGCCCGTCTTGAC
CGCAGCGGAGTAACCCATCG

Downstream 100 bases:

>100_bases
TCATGATTCTTATCGACAAAGCTCTACAGTTGCGCGCCGAGCGCCGCCAGCCCGTGCGCGTCGCCATGGTCGGCGCCGGG
TTTATGGGGCTGGGCATCGC

Product: dTDP-4-dehydrorhamnose 3,5-epimerase

Products: NA

Alternate protein names: Thymidine diphospho-4-keto-rhamnose 3,5-epimerase; dTDP-4-keto-6-deoxyglucose 3,5-epimerase; dTDP-6-deoxy-D-xylo-4-hexulose 3,5-epimerase; dTDP-L-rhamnose synthase [H]

Number of amino acids: Translated: 182; Mature: 182

Protein sequence:

>182_residues
MQFINTKLAGAWIIELERREDERGFFARTFCAREFEAQGLAGTFAQSNLSYNHRAGTLRGLHYQVAPALETKLVRCTRGA
IYDVIVDLRPGSRTYLQHIGVELSEDNRWALYVPGLFAHGYQALTDGAEVLYQVGEFYTPGYERGLRYDDPALAIDWPLP
VSVLSTKDNGWPLLAPAMQEQH

Sequences:

>Translated_182_residues
MQFINTKLAGAWIIELERREDERGFFARTFCAREFEAQGLAGTFAQSNLSYNHRAGTLRGLHYQVAPALETKLVRCTRGA
IYDVIVDLRPGSRTYLQHIGVELSEDNRWALYVPGLFAHGYQALTDGAEVLYQVGEFYTPGYERGLRYDDPALAIDWPLP
VSVLSTKDNGWPLLAPAMQEQH
>Mature_182_residues
MQFINTKLAGAWIIELERREDERGFFARTFCAREFEAQGLAGTFAQSNLSYNHRAGTLRGLHYQVAPALETKLVRCTRGA
IYDVIVDLRPGSRTYLQHIGVELSEDNRWALYVPGLFAHGYQALTDGAEVLYQVGEFYTPGYERGLRYDDPALAIDWPLP
VSVLSTKDNGWPLLAPAMQEQH

Specific function: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose [H]

COG id: COG1898

COG function: function code M; dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI1788350, Length=170, Percent_Identity=40.5882352941176, Blast_Score=124, Evalue=5e-30,
Organism=Caenorhabditis elegans, GI17550412, Length=161, Percent_Identity=38.5093167701863, Blast_Score=98, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR000888
- InterPro:   IPR014710
- ProDom:   PD001462 [H]

Pfam domain/function: PF00908 dTDP_sugar_isom [H]

EC number: =5.1.3.13 [H]

Molecular weight: Translated: 20566; Mature: 20566

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQFINTKLAGAWIIELERREDERGFFARTFCAREFEAQGLAGTFAQSNLSYNHRAGTLRG
CCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCCCEEEC
LHYQVAPALETKLVRCTRGAIYDVIVDLRPGSRTYLQHIGVELSEDNRWALYVPGLFAHG
EEEEECHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHCCCEECCCCEEEEEECCHHHCC
YQALTDGAEVLYQVGEFYTPGYERGLRYDDPALAIDWPLPVSVLSTKDNGWPLLAPAMQE
HHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCEEEECCCCEEEEEECCCCCEEECCCCCC
QH
CC
>Mature Secondary Structure
MQFINTKLAGAWIIELERREDERGFFARTFCAREFEAQGLAGTFAQSNLSYNHRAGTLRG
CCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCCCEEEC
LHYQVAPALETKLVRCTRGAIYDVIVDLRPGSRTYLQHIGVELSEDNRWALYVPGLFAHG
EEEEECHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHCCCEECCCCEEEEEECCHHHCC
YQALTDGAEVLYQVGEFYTPGYERGLRYDDPALAIDWPLPVSVLSTKDNGWPLLAPAMQE
HHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCEEEECCCCEEEEEECCCCCEEECCCCCC
QH
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463; 10827167 [H]