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The map label for this gene is ctaD [H]

Identifier: 37521732

GI number: 37521732

Start: 2311880

End: 2313562

Strand: Reverse

Name: ctaD [H]

Synonym: gvip299

Alternate gene names: 37521732

Gene position: 2313562-2311880 (Counterclockwise)

Preceding gene: 37521733

Following gene: 37521731

Centisome position: 49.66

GC content: 61.68

Gene sequence:

>1683_bases
ATGGTTGAAACCACCCAACAACGTGTCGAGCAACGGCAGCCGGAGCCTCTGGGCGATTGGCGCCGCTACTTCAGCTTCTG
TGTCGATCACAAGGTGATCGGCATCCAGTATCTGGTGACGACCTTTTTCTTCTACCTGCTGGGCGGCGCCCTGGCGATGG
TCATCCGCGCCGAGCTGATGACCCCTGGGGCCGAACTGGATCGTTCGCTTTACAACGGCGTGTTCACCATCCACGCGACG
ATCATGATCTTTCTTTGGATCATTCCGACCCTGGCGGGCTTCGGCAACTTCCTGGTGCCTTTGATGATTGGCGCCCGGGA
CATGGCCTTTCCGCGGCTCAACGCCCTCAGCTTCTGGATGATTCCGCCCGGGGGGCTGCTTTTGCTTTCGAGCTTTTTTG
TGCAAAGCGGTGCAGCCGGTGCCGGTTGGACCTCCTATCCGCCCCTCAGCACCCAGCAGGTGCAGGTGGGCGACTTGCTG
GTGACCAACTTCGGTCAGGTCATCTGGATTGCAAGCGTCGTCTTTTTGGGCACCTCCTCAATCCTGGCAGCCCTCAACTT
CATCGTCACGATCGTGGCGATGCGCACCGAGGGGATGGAGCTGTTTCGGATGCCGCTGTTTTGCTGGGCGACGCTCACCG
CCTCGTGCATCACGCTGCTGGGCACACCGGTCCTGGCCGGAGCGGTGATTTTGCTCGCCTTCGACCTGCTCCTTGGAACC
GTCTTTTTCAACCCGACCGGCGGCGGCGACCCGGTGGTCTACCAGCACATGTTCTGGTTCTACTCCCACCCGGCGGTCTA
CATCATGGTCCTGCCGGCGATGGGAATCATCTCCGAGGTGCTGCCGGTCTTCTCGCGCAAACCGATCTTCGGCTACAAGG
CGATCGCCATTTCGAGCATGGGCATCGCCGTGCTGGGCTTTCTGGTCTGGGCGCACCACATGTTCACCTCCGGCACCCCC
GACTGGCTGCGCATGTTCTTCATGGTCACTTCGTTTTTGATCGCGGTACCCACCGGCATCAAGGTCTTCAGCTGGCTGGG
CACGATCTGGGGCGGCAAGCTGGAACTGTCCTCGGCGATGCTCTTTGCCATGGGCTTCGTCTCGATGTTCGTCGTGGGCG
GCCTGTCGGGCATCATGCTCGCCTCGGTGCCGGTGGATATCCACGTCCACGACACCTACTTCGTGGTCGCCCACCTGCAC
TACGTGCTCTTCGGCGGCAGCGTCTTCGCCATCTACGCGGGGCTTTACTACTGGTTTCCGAAGATGACCGGGCGGCTGCT
CAACGAGACCTGGGGCAAGATCCACTTCGCCCTCACCTTCATCGGCTTCAACCTGTGCTTCTTGCCGATGCACCAGTTGG
GACTGCAGGGAATGCCCCGGCGCGTCGCCGAGTACGCCGAGCAGTTCCAGAGCCTCAACGTGCTGGTGAGTATCGGCGGC
TTCCTGCTGGGTATCTCGACGTTGCCCTTTTTGTTCAATGCCATCTACAGCTGGCTGTGGGGACCGAAGGCTCCGGCCAA
TCCCTGGCGGGCATTGACCCTGGAATGGACCACCGCCTCGCCGCCGCCGGTCGAGAACTTCGAGTACCTGCCGGTGGTCA
CCGCCGGCCCTTACGAGTACGGCACGGTCGGCTCCAGCCCCGAGGGCAACACCCCGACCGCCATCTCCCAACCCAAGTCC
TGA

Upstream 100 bases:

>100_bases
TCCGGCCGCCGCCTACGGGGCGACGAGCGGCACGACCGTGCTGCAATCCGAACAAACCCGCGCCCTCGTCGGGCACCTGC
GCGCACAAGGACAGTAAGCA

Downstream 100 bases:

>100_bases
CACTCCGGATAGACACGATGCAATCACCGATCAGTTCCAACGACGCGGCGATGTCCCAGGCAATCGGCCATAGCGACGGC
CACGGCCACGGCCACGGCGA

Product: cytochrome c oxidase subunit I

Products: NA

Alternate protein names: Cytochrome aa3 subunit 1; Cytochrome c oxidase polypeptide I; Oxidase aa(3) subunit 1 [H]

Number of amino acids: Translated: 560; Mature: 560

Protein sequence:

>560_residues
MVETTQQRVEQRQPEPLGDWRRYFSFCVDHKVIGIQYLVTTFFFYLLGGALAMVIRAELMTPGAELDRSLYNGVFTIHAT
IMIFLWIIPTLAGFGNFLVPLMIGARDMAFPRLNALSFWMIPPGGLLLLSSFFVQSGAAGAGWTSYPPLSTQQVQVGDLL
VTNFGQVIWIASVVFLGTSSILAALNFIVTIVAMRTEGMELFRMPLFCWATLTASCITLLGTPVLAGAVILLAFDLLLGT
VFFNPTGGGDPVVYQHMFWFYSHPAVYIMVLPAMGIISEVLPVFSRKPIFGYKAIAISSMGIAVLGFLVWAHHMFTSGTP
DWLRMFFMVTSFLIAVPTGIKVFSWLGTIWGGKLELSSAMLFAMGFVSMFVVGGLSGIMLASVPVDIHVHDTYFVVAHLH
YVLFGGSVFAIYAGLYYWFPKMTGRLLNETWGKIHFALTFIGFNLCFLPMHQLGLQGMPRRVAEYAEQFQSLNVLVSIGG
FLLGISTLPFLFNAIYSWLWGPKAPANPWRALTLEWTTASPPPVENFEYLPVVTAGPYEYGTVGSSPEGNTPTAISQPKS

Sequences:

>Translated_560_residues
MVETTQQRVEQRQPEPLGDWRRYFSFCVDHKVIGIQYLVTTFFFYLLGGALAMVIRAELMTPGAELDRSLYNGVFTIHAT
IMIFLWIIPTLAGFGNFLVPLMIGARDMAFPRLNALSFWMIPPGGLLLLSSFFVQSGAAGAGWTSYPPLSTQQVQVGDLL
VTNFGQVIWIASVVFLGTSSILAALNFIVTIVAMRTEGMELFRMPLFCWATLTASCITLLGTPVLAGAVILLAFDLLLGT
VFFNPTGGGDPVVYQHMFWFYSHPAVYIMVLPAMGIISEVLPVFSRKPIFGYKAIAISSMGIAVLGFLVWAHHMFTSGTP
DWLRMFFMVTSFLIAVPTGIKVFSWLGTIWGGKLELSSAMLFAMGFVSMFVVGGLSGIMLASVPVDIHVHDTYFVVAHLH
YVLFGGSVFAIYAGLYYWFPKMTGRLLNETWGKIHFALTFIGFNLCFLPMHQLGLQGMPRRVAEYAEQFQSLNVLVSIGG
FLLGISTLPFLFNAIYSWLWGPKAPANPWRALTLEWTTASPPPVENFEYLPVVTAGPYEYGTVGSSPEGNTPTAISQPKS
>Mature_560_residues
MVETTQQRVEQRQPEPLGDWRRYFSFCVDHKVIGIQYLVTTFFFYLLGGALAMVIRAELMTPGAELDRSLYNGVFTIHAT
IMIFLWIIPTLAGFGNFLVPLMIGARDMAFPRLNALSFWMIPPGGLLLLSSFFVQSGAAGAGWTSYPPLSTQQVQVGDLL
VTNFGQVIWIASVVFLGTSSILAALNFIVTIVAMRTEGMELFRMPLFCWATLTASCITLLGTPVLAGAVILLAFDLLLGT
VFFNPTGGGDPVVYQHMFWFYSHPAVYIMVLPAMGIISEVLPVFSRKPIFGYKAIAISSMGIAVLGFLVWAHHMFTSGTP
DWLRMFFMVTSFLIAVPTGIKVFSWLGTIWGGKLELSSAMLFAMGFVSMFVVGGLSGIMLASVPVDIHVHDTYFVVAHLH
YVLFGGSVFAIYAGLYYWFPKMTGRLLNETWGKIHFALTFIGFNLCFLPMHQLGLQGMPRRVAEYAEQFQSLNVLVSIGG
FLLGISTLPFLFNAIYSWLWGPKAPANPWRALTLEWTTASPPPVENFEYLPVVTAGPYEYGTVGSSPEGNTPTAISQPKS

Specific function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=506, Percent_Identity=46.2450592885375, Blast_Score=405, Evalue=1e-113,
Organism=Escherichia coli, GI1786634, Length=522, Percent_Identity=39.8467432950192, Blast_Score=368, Evalue=1e-103,
Organism=Saccharomyces cerevisiae, GI6226519, Length=533, Percent_Identity=40.9005628517824, Blast_Score=399, Evalue=1e-112,
Organism=Saccharomyces cerevisiae, GI6226524, Length=328, Percent_Identity=42.6829268292683, Blast_Score=261, Evalue=2e-70,
Organism=Saccharomyces cerevisiae, GI6226523, Length=251, Percent_Identity=38.6454183266932, Blast_Score=164, Evalue=3e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014241 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 61791; Mature: 61791

Theoretical pI: Translated: 7.15; Mature: 7.15

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVETTQQRVEQRQPEPLGDWRRYFSFCVDHKVIGIQYLVTTFFFYLLGGALAMVIRAELM
CCCCHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
TPGAELDRSLYNGVFTIHATIMIFLWIIPTLAGFGNFLVPLMIGARDMAFPRLNALSFWM
CCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCEEEEE
IPPGGLLLLSSFFVQSGAAGAGWTSYPPLSTQQVQVGDLLVTNFGQVIWIASVVFLGTSS
ECCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHH
ILAALNFIVTIVAMRTEGMELFRMPLFCWATLTASCITLLGTPVLAGAVILLAFDLLLGT
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
VFFNPTGGGDPVVYQHMFWFYSHPAVYIMVLPAMGIISEVLPVFSRKPIFGYKAIAISSM
HEECCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
GIAVLGFLVWAHHMFTSGTPDWLRMFFMVTSFLIAVPTGIKVFSWLGTIWGGKLELSSAM
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHH
LFAMGFVSMFVVGGLSGIMLASVPVDIHVHDTYFVVAHLHYVLFGGSVFAIYAGLYYWFP
HHHHHHHHHHHHHCCHHHHHEECCEEEEECCHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
KMTGRLLNETWGKIHFALTFIGFNLCFLPMHQLGLQGMPRRVAEYAEQFQSLNVLVSIGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
FLLGISTLPFLFNAIYSWLWGPKAPANPWRALTLEWTTASPPPVENFEYLPVVTAGPYEY
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCCCCCCCEEEEEECCCCCC
GTVGSSPEGNTPTAISQPKS
CCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MVETTQQRVEQRQPEPLGDWRRYFSFCVDHKVIGIQYLVTTFFFYLLGGALAMVIRAELM
CCCCHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
TPGAELDRSLYNGVFTIHATIMIFLWIIPTLAGFGNFLVPLMIGARDMAFPRLNALSFWM
CCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCEEEEE
IPPGGLLLLSSFFVQSGAAGAGWTSYPPLSTQQVQVGDLLVTNFGQVIWIASVVFLGTSS
ECCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHH
ILAALNFIVTIVAMRTEGMELFRMPLFCWATLTASCITLLGTPVLAGAVILLAFDLLLGT
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
VFFNPTGGGDPVVYQHMFWFYSHPAVYIMVLPAMGIISEVLPVFSRKPIFGYKAIAISSM
HEECCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
GIAVLGFLVWAHHMFTSGTPDWLRMFFMVTSFLIAVPTGIKVFSWLGTIWGGKLELSSAM
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHH
LFAMGFVSMFVVGGLSGIMLASVPVDIHVHDTYFVVAHLHYVLFGGSVFAIYAGLYYWFP
HHHHHHHHHHHHHCCHHHHHEECCEEEEECCHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
KMTGRLLNETWGKIHFALTFIGFNLCFLPMHQLGLQGMPRRVAEYAEQFQSLNVLVSIGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
FLLGISTLPFLFNAIYSWLWGPKAPANPWRALTLEWTTASPPPVENFEYLPVVTAGPYEY
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCCCCCCCEEEEEECCCCCC
GTVGSSPEGNTPTAISQPKS
CCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8387368; 8905231 [H]