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The map label for this gene is ecaB [H]

Identifier: 37521657

GI number: 37521657

Start: 2241278

End: 2241982

Strand: Direct

Name: ecaB [H]

Synonym: gvip281

Alternate gene names: 37521657

Gene position: 2241278-2241982 (Clockwise)

Preceding gene: 37521656

Following gene: 37521658

Centisome position: 48.11

GC content: 62.98

Gene sequence:

>705_bases
ATGATCGAGCAACAGCCTAGATTCTTCTCGCGCCGGGATCTGTTTGTAACCGCCGGTACGGGGTTGTTGGCCGGGCTGAT
CACCGGTGCTTTACCCAGGAGCGCGGGCGCCACCACCAACCTCACCGCCGAGCAGGCGCTCGAGCGGCTCGTCGAAGGCA
ACAAGCGCTGGATCCAGTTCAAACTCACCGGAGCGGACCGCACCAAAAGCCGACTGGCGGAAGTGGCCAAAGGCCAAAGT
CCCTTCGCCGCCTTCGTCAGCTGCGCCGATTCGCGCGTACCGGCTGAACTTATCTTCGATCAGGGCCTGGGAGACCTGTT
CATGAACCGGGTGGCAGGCAACGTCCTCGATGAGATGATGCTGGGCAGCCTCGAATTTGCCACCTCCGTCCTCGGAGCGC
CCCTGGTCGTGGTCATGGGCCATCAGCGCTGTGGTGCGGTGCAGGCGGCGGTCAAAGCGGTGACCGAGGGCACCCAGTTT
CCGGGCCACCTGGCCAATTTTGTCGATGCCATCCGCCCGGCGGCGGCGAGCATCAAGGGCATGCCGGGCGACCCGGTGGA
AAACGCCATCCGTGCCAACGTGCTCATCACCGTCGACAAGATCAAAACGGCCCCGCCCATCATCAGCAAGCTGGTGGAGC
AGAGCAAAGTCAAGGTCGTGGGCGCCCGCTACGACCTCGATACCGGTGCTGTGAGCTTTTACTAA

Upstream 100 bases:

>100_bases
CAAGCTCGTTGCTCCCACCGAGCGCTGAAACCCGGCACCTGAAACCTAAAATCTGTCCAATCCAGAGATTGATTTCGATT
CACACCTGCAGGAGGACCCT

Downstream 100 bases:

>100_bases
TTTTGTGGAGAACGCTTCGATGTCCGTTTTTCTCGAAGTCGAACAGATCGACAAAGTCTTCGCTTTGCCGGGAGGCGGCA
ACTACATCGCCCTCAAAGGT

Product: periplasmic beta-type carbonic anhydrase

Products: NA

Alternate protein names: Carbonate dehydratase [H]

Number of amino acids: Translated: 234; Mature: 234

Protein sequence:

>234_residues
MIEQQPRFFSRRDLFVTAGTGLLAGLITGALPRSAGATTNLTAEQALERLVEGNKRWIQFKLTGADRTKSRLAEVAKGQS
PFAAFVSCADSRVPAELIFDQGLGDLFMNRVAGNVLDEMMLGSLEFATSVLGAPLVVVMGHQRCGAVQAAVKAVTEGTQF
PGHLANFVDAIRPAAASIKGMPGDPVENAIRANVLITVDKIKTAPPIISKLVEQSKVKVVGARYDLDTGAVSFY

Sequences:

>Translated_234_residues
MIEQQPRFFSRRDLFVTAGTGLLAGLITGALPRSAGATTNLTAEQALERLVEGNKRWIQFKLTGADRTKSRLAEVAKGQS
PFAAFVSCADSRVPAELIFDQGLGDLFMNRVAGNVLDEMMLGSLEFATSVLGAPLVVVMGHQRCGAVQAAVKAVTEGTQF
PGHLANFVDAIRPAAASIKGMPGDPVENAIRANVLITVDKIKTAPPIISKLVEQSKVKVVGARYDLDTGAVSFY
>Mature_234_residues
MIEQQPRFFSRRDLFVTAGTGLLAGLITGALPRSAGATTNLTAEQALERLVEGNKRWIQFKLTGADRTKSRLAEVAKGQS
PFAAFVSCADSRVPAELIFDQGLGDLFMNRVAGNVLDEMMLGSLEFATSVLGAPLVVVMGHQRCGAVQAAVKAVTEGTQF
PGHLANFVDAIRPAAASIKGMPGDPVENAIRANVLITVDKIKTAPPIISKLVEQSKVKVVGARYDLDTGAVSFY

Specific function: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate [H]

COG id: COG0288

COG function: function code P; Carbonic anhydrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-class carbonic anhydrase family [H]

Homologues:

Organism=Escherichia coli, GI1786534, Length=198, Percent_Identity=25.2525252525253, Blast_Score=74, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001765
- InterPro:   IPR015892 [H]

Pfam domain/function: PF00484 Pro_CA [H]

EC number: =4.2.1.1 [H]

Molecular weight: Translated: 24872; Mature: 24872

Theoretical pI: Translated: 9.22; Mature: 9.22

Prosite motif: PS00704 PROK_CO2_ANHYDRASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEQQPRFFSRRDLFVTAGTGLLAGLITGALPRSAGATTNLTAEQALERLVEGNKRWIQF
CCCCCCCCCCCCCEEEECCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEE
KLTGADRTKSRLAEVAKGQSPFAAFVSCADSRVPAELIFDQGLGDLFMNRVAGNVLDEMM
EECCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHH
LGSLEFATSVLGAPLVVVMGHQRCGAVQAAVKAVTEGTQFPGHLANFVDAIRPAAASIKG
HHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCC
MPGDPVENAIRANVLITVDKIKTAPPIISKLVEQSKVKVVGARYDLDTGAVSFY
CCCCHHHHHHHCCEEEEECCCCCCCHHHHHHHHHHHEEEEEEEEECCCCCEECC
>Mature Secondary Structure
MIEQQPRFFSRRDLFVTAGTGLLAGLITGALPRSAGATTNLTAEQALERLVEGNKRWIQF
CCCCCCCCCCCCCEEEECCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEE
KLTGADRTKSRLAEVAKGQSPFAAFVSCADSRVPAELIFDQGLGDLFMNRVAGNVLDEMM
EECCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHH
LGSLEFATSVLGAPLVVVMGHQRCGAVQAAVKAVTEGTQFPGHLANFVDAIRPAAASIKG
HHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCC
MPGDPVENAIRANVLITVDKIKTAPPIISKLVEQSKVKVVGARYDLDTGAVSFY
CCCCHHHHHHHCCEEEEECCCCCCCHHHHHHHHHHHEEEEEEEEECCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]