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The map label for this gene is copB [H]

Identifier: 37521566

GI number: 37521566

Start: 2145434

End: 2145925

Strand: Direct

Name: copB [H]

Synonym: glr1997

Alternate gene names: 37521566

Gene position: 2145434-2145925 (Clockwise)

Preceding gene: 37521565

Following gene: 37521569

Centisome position: 46.05

GC content: 64.02

Gene sequence:

>492_bases
GTGGTGATGCTCACCGGCGATAGCAACCCGGTGACCCGCTGGGTGGCGGGGGAATTGGGAATCGACATGTACCTCGCCCA
GGTTTTGCCGCAGGCCAAATCCGCGAAAGTCCGGCAACTCCAGCAAGAAGGCGCGAAAGTGGCGATGGTCGGCGACGGAG
TCAACGACGCCCCGGCTATTGCCCAAGTGGACGTGGGCATCGCCATCGGAGCGGGCACCGACGTGGCGCGCGCCACGTCG
GGGATCGTGCTGGTGCGCAACGACCCGCGCGACATCGCCAGGATCGTCGCCCTTAGCAAAGCGAGCTACGGCAAAATGGT
CCAGAACTTGATCTGGGCTGTAGGATACAACGCCGTCTCCCTGCCGCTCGCCGGCGGGGTGCTGGCCGGTGTGGGCTTCG
TGCTGCCGGTGTGGGTAGGGGCGGTGCTGATGTCACTGAGTACGATGATTGTCGCCATCAACGCCCAGACGCTGCGCGGC
TCAAAACTTTAA

Upstream 100 bases:

>100_bases
TGGGGCGAGCAAGGCCAAACCGTCGTCTATCTTGTCGAAGAGGACCGGGCCCAAGCCGCCTTTCGCCCTGGCCGACGTGA
TGCGGCAGTAGGGCATCTGG

Downstream 100 bases:

>100_bases
TTCATAAACCGAGAATCCCGAGGCTTTAGCCGTGTGAAGTGTCAGGTTGTTTCCTTGCCTGGCAGGAAATCCGGGTTCAG
GCTTTGTTCCAGCGTAAAAG

Product: cation transporting ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 163; Mature: 163

Protein sequence:

>163_residues
MVMLTGDSNPVTRWVAGELGIDMYLAQVLPQAKSAKVRQLQQEGAKVAMVGDGVNDAPAIAQVDVGIAIGAGTDVARATS
GIVLVRNDPRDIARIVALSKASYGKMVQNLIWAVGYNAVSLPLAGGVLAGVGFVLPVWVGAVLMSLSTMIVAINAQTLRG
SKL

Sequences:

>Translated_163_residues
MVMLTGDSNPVTRWVAGELGIDMYLAQVLPQAKSAKVRQLQQEGAKVAMVGDGVNDAPAIAQVDVGIAIGAGTDVARATS
GIVLVRNDPRDIARIVALSKASYGKMVQNLIWAVGYNAVSLPLAGGVLAGVGFVLPVWVGAVLMSLSTMIVAINAQTLRG
SKL
>Mature_163_residues
MVMLTGDSNPVTRWVAGELGIDMYLAQVLPQAKSAKVRQLQQEGAKVAMVGDGVNDAPAIAQVDVGIAIGAGTDVARATS
GIVLVRNDPRDIARIVALSKASYGKMVQNLIWAVGYNAVSLPLAGGVLAGVGFVLPVWVGAVLMSLSTMIVAINAQTLRG
SKL

Specific function: Probably involved in copper export [H]

COG id: COG2217

COG function: function code P; Cation transport ATPase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily [H]

Homologues:

Organism=Homo sapiens, GI115529486, Length=140, Percent_Identity=47.1428571428571, Blast_Score=137, Evalue=4e-33,
Organism=Homo sapiens, GI55743071, Length=140, Percent_Identity=48.5714285714286, Blast_Score=136, Evalue=8e-33,
Organism=Homo sapiens, GI55743073, Length=140, Percent_Identity=48.5714285714286, Blast_Score=136, Evalue=9e-33,
Organism=Homo sapiens, GI209413709, Length=140, Percent_Identity=35, Blast_Score=67, Evalue=5e-12,
Organism=Homo sapiens, GI27886529, Length=139, Percent_Identity=33.8129496402878, Blast_Score=67, Evalue=6e-12,
Organism=Homo sapiens, GI24638454, Length=140, Percent_Identity=35, Blast_Score=67, Evalue=6e-12,
Organism=Homo sapiens, GI310128958, Length=93, Percent_Identity=39.7849462365591, Blast_Score=67, Evalue=7e-12,
Organism=Homo sapiens, GI4502285, Length=140, Percent_Identity=35, Blast_Score=67, Evalue=7e-12,
Organism=Homo sapiens, GI10835220, Length=139, Percent_Identity=33.8129496402878, Blast_Score=67, Evalue=7e-12,
Organism=Homo sapiens, GI28373115, Length=93, Percent_Identity=38.7096774193548, Blast_Score=65, Evalue=4e-11,
Organism=Homo sapiens, GI28373111, Length=93, Percent_Identity=38.7096774193548, Blast_Score=65, Evalue=4e-11,
Organism=Homo sapiens, GI28373113, Length=93, Percent_Identity=38.7096774193548, Blast_Score=65, Evalue=4e-11,
Organism=Homo sapiens, GI28373103, Length=93, Percent_Identity=38.7096774193548, Blast_Score=65, Evalue=4e-11,
Organism=Homo sapiens, GI28373109, Length=93, Percent_Identity=38.7096774193548, Blast_Score=65, Evalue=4e-11,
Organism=Homo sapiens, GI28373105, Length=93, Percent_Identity=38.7096774193548, Blast_Score=65, Evalue=4e-11,
Organism=Homo sapiens, GI28373107, Length=93, Percent_Identity=38.7096774193548, Blast_Score=64, Evalue=5e-11,
Organism=Escherichia coli, GI1786691, Length=160, Percent_Identity=47.5, Blast_Score=129, Evalue=8e-32,
Organism=Escherichia coli, GI1789879, Length=120, Percent_Identity=40.8333333333333, Blast_Score=89, Evalue=1e-19,
Organism=Escherichia coli, GI1786914, Length=99, Percent_Identity=43.4343434343434, Blast_Score=82, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17556548, Length=138, Percent_Identity=47.8260869565217, Blast_Score=119, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI193210130, Length=93, Percent_Identity=39.7849462365591, Blast_Score=69, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17554158, Length=93, Percent_Identity=39.7849462365591, Blast_Score=69, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71988506, Length=93, Percent_Identity=39.7849462365591, Blast_Score=69, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6320475, Length=154, Percent_Identity=38.3116883116883, Blast_Score=97, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6319772, Length=166, Percent_Identity=26.5060240963855, Blast_Score=65, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6321271, Length=166, Percent_Identity=30.7228915662651, Blast_Score=65, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6325221, Length=99, Percent_Identity=37.3737373737374, Blast_Score=64, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6321430, Length=99, Percent_Identity=37.3737373737374, Blast_Score=64, Evalue=9e-12,
Organism=Drosophila melanogaster, GI221329854, Length=144, Percent_Identity=47.2222222222222, Blast_Score=132, Evalue=7e-32,
Organism=Drosophila melanogaster, GI24762455, Length=139, Percent_Identity=33.0935251798561, Blast_Score=67, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24762453, Length=139, Percent_Identity=33.0935251798561, Blast_Score=67, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24762447, Length=139, Percent_Identity=33.0935251798561, Blast_Score=67, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24762457, Length=139, Percent_Identity=33.0935251798561, Blast_Score=67, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24762449, Length=139, Percent_Identity=33.0935251798561, Blast_Score=67, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24762445, Length=139, Percent_Identity=33.0935251798561, Blast_Score=67, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24762451, Length=139, Percent_Identity=33.0935251798561, Blast_Score=67, Evalue=5e-12,
Organism=Drosophila melanogaster, GI17136664, Length=139, Percent_Identity=33.0935251798561, Blast_Score=67, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008250
- InterPro:   IPR006403
- InterPro:   IPR000695
- InterPro:   IPR006416
- InterPro:   IPR001757
- InterPro:   IPR018303
- InterPro:   IPR005834
- InterPro:   IPR023214 [H]

Pfam domain/function: PF00122 E1-E2_ATPase; PF00702 Hydrolase [H]

EC number: =3.6.3.4 [H]

Molecular weight: Translated: 16839; Mature: 16839

Theoretical pI: Translated: 9.96; Mature: 9.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVMLTGDSNPVTRWVAGELGIDMYLAQVLPQAKSAKVRQLQQEGAKVAMVGDGVNDAPAI
CEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCEEEEEECCCCCCCCE
AQVDVGIAIGAGTDVARATSGIVLVRNDPRDIARIVALSKASYGKMVQNLIWAVGYNAVS
EEEECCEEEECCCCHHHHHCCEEEEECCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCEEE
LPLAGGVLAGVGFVLPVWVGAVLMSLSTMIVAINAQTLRGSKL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEECHHCCCCCC
>Mature Secondary Structure
MVMLTGDSNPVTRWVAGELGIDMYLAQVLPQAKSAKVRQLQQEGAKVAMVGDGVNDAPAI
CEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCEEEEEECCCCCCCCE
AQVDVGIAIGAGTDVARATSGIVLVRNDPRDIARIVALSKASYGKMVQNLIWAVGYNAVS
EEEECCEEEECCCCHHHHHCCEEEEECCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCEEE
LPLAGGVLAGVGFVLPVWVGAVLMSLSTMIVAINAQTLRGSKL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEECHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]