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The map label for this gene is murG

Identifier: 37521240

GI number: 37521240

Start: 1783672

End: 1784745

Strand: Reverse

Name: murG

Synonym: gll1671

Alternate gene names: 37521240

Gene position: 1784745-1783672 (Counterclockwise)

Preceding gene: 37521243

Following gene: 37521239

Centisome position: 38.31

GC content: 67.32

Gene sequence:

>1074_bases
ATGCCCAAGCCGCGGTTGCTGATTGCCGCGAGCGGCACCGGCGGACATATCTTTCCGGCTCTGGCGGTGGCTGGCGAATT
GAGCGAATTTGAGATCGCCTGGCTTGGGGTTCCCGACCGGCTGGAGAACAAACTGGTTCCCGGCCGCTACCCGCTGCACA
CCGTCGCTCTACAGGGGCTCAACCGCAAACCCGGCCCCCAGTGGCTCGAAGCCGCCTCCCAGACCTTTGCCGCCTACCGC
TACGCCCGGAACCTATTGAGTCAGGAACGCTTCGCGGGGGTGTTCACCACCGGCGGCTACATCGCCGCCCCGGCGGTGCT
CGCCGCCCGCAGCCTGAACCTGCCTGCCATCGGTCACGAATCGAATGTGCTGCCGGGCAAGGTGATCCGCTACCTCGCCC
GCTGGATGCGCTCCTTGGGCCTCGGCTTCGCCGAATCGGCCACCTACGTCAGTGGGGCCACGACCCGCTGGGTGGGTACA
CCGGTGCGCCCCGAGTTTTTGATCTCCCCCAATCCGCTGCTCGATGTTCCGGTGCCGCCCGAGGCGCCCTTGATCGTGGT
GATGGGGGGCTCCCAGGGAGCCAGGGCGATCAATCAGATGGTGGGCGAGTGCGCCCCCGGCTGGCTTGAGCGCGGCTGGT
GGATAGTACACCTCACTGGTGCCGGTGAATACGATGCCGTGCGCGAGGGTACCCCCGACCACCCCGCTTACCGCATCTAC
GCCTTCTGGGAAAAGATGGCCCCGCTGCTCTCCCGCGCGGATCTGGCCATCAGCCGCGCCGGGGCGGCGACCCTCAGCGA
ATTGCTCGTCACCGGCACCCCGTCGCTTTTGATTCCCTATCCGTTTGCCGCCGAGGATCACCAGAGCGTCAACGCCGCAG
CCCTCGTGCGCGCCGGGGCGGCTCTCCAGTTTTCTCAAGCGGCCCTGAGTGCCCCGCTCCTGGACCGCACCGTCCAGGCC
CTCCTGGACAATCCCGAAACCCTGGCCAGGATGGCTGCGAGCGCACGCAGGCTCGCGGTTCCCGATGCCGCCCGCCGCAC
AGCCGATTTGGTGCGCGAGTGCGTTCGCCATTAA

Upstream 100 bases:

>100_bases
ACTAGAGTATCCCAGGAGTCTGCTCCCCGCGATCGGATTCTTTACATTCGGGATGGCGGTTGTTTTTAGATCCTGAGAGA
TGGTTCATACGGTTTCCTCT

Downstream 100 bases:

>100_bases
AAAGGCTGTCGGCAGTCCGGCTGCGATAGCATGGCCCTACAGGATTCAAGCGAAACGACAATGCCTATCCAGGGCGAAAA
CCTGCTGAATGAGTATGGAA

Product: UDP-N-acetylglucosamine-N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase

Number of amino acids: Translated: 357; Mature: 356

Protein sequence:

>357_residues
MPKPRLLIAASGTGGHIFPALAVAGELSEFEIAWLGVPDRLENKLVPGRYPLHTVALQGLNRKPGPQWLEAASQTFAAYR
YARNLLSQERFAGVFTTGGYIAAPAVLAARSLNLPAIGHESNVLPGKVIRYLARWMRSLGLGFAESATYVSGATTRWVGT
PVRPEFLISPNPLLDVPVPPEAPLIVVMGGSQGARAINQMVGECAPGWLERGWWIVHLTGAGEYDAVREGTPDHPAYRIY
AFWEKMAPLLSRADLAISRAGAATLSELLVTGTPSLLIPYPFAAEDHQSVNAAALVRAGAALQFSQAALSAPLLDRTVQA
LLDNPETLARMAASARRLAVPDAARRTADLVRECVRH

Sequences:

>Translated_357_residues
MPKPRLLIAASGTGGHIFPALAVAGELSEFEIAWLGVPDRLENKLVPGRYPLHTVALQGLNRKPGPQWLEAASQTFAAYR
YARNLLSQERFAGVFTTGGYIAAPAVLAARSLNLPAIGHESNVLPGKVIRYLARWMRSLGLGFAESATYVSGATTRWVGT
PVRPEFLISPNPLLDVPVPPEAPLIVVMGGSQGARAINQMVGECAPGWLERGWWIVHLTGAGEYDAVREGTPDHPAYRIY
AFWEKMAPLLSRADLAISRAGAATLSELLVTGTPSLLIPYPFAAEDHQSVNAAALVRAGAALQFSQAALSAPLLDRTVQA
LLDNPETLARMAASARRLAVPDAARRTADLVRECVRH
>Mature_356_residues
PKPRLLIAASGTGGHIFPALAVAGELSEFEIAWLGVPDRLENKLVPGRYPLHTVALQGLNRKPGPQWLEAASQTFAAYRY
ARNLLSQERFAGVFTTGGYIAAPAVLAARSLNLPAIGHESNVLPGKVIRYLARWMRSLGLGFAESATYVSGATTRWVGTP
VRPEFLISPNPLLDVPVPPEAPLIVVMGGSQGARAINQMVGECAPGWLERGWWIVHLTGAGEYDAVREGTPDHPAYRIYA
FWEKMAPLLSRADLAISRAGAATLSELLVTGTPSLLIPYPFAAEDHQSVNAAALVRAGAALQFSQAALSAPLLDRTVQAL
LDNPETLARMAASARRLAVPDAARRTADLVRECVRH

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily

Homologues:

Organism=Escherichia coli, GI1786278, Length=360, Percent_Identity=33.8888888888889, Blast_Score=159, Evalue=3e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURG_GLOVI (Q7MBC4)

Other databases:

- EMBL:   BA000045
- RefSeq:   NP_924617.1
- ProteinModelPortal:   Q7MBC4
- GeneID:   2598451
- GenomeReviews:   BA000045_GR
- KEGG:   gvi:gll1671
- NMPDR:   fig|251221.1.peg.1671
- HOGENOM:   HBG617076
- OMA:   IGFGGYP
- BioCyc:   GVIO251221:GLL1671-MONOMER
- BRENDA:   2.4.1.227
- HAMAP:   MF_00033
- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235
- TIGRFAMs:   TIGR01133

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28

EC number: =2.4.1.227

Molecular weight: Translated: 38316; Mature: 38184

Theoretical pI: Translated: 9.28; Mature: 9.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKPRLLIAASGTGGHIFPALAVAGELSEFEIAWLGVPDRLENKLVPGRYPLHTVALQGL
CCCCCEEEEECCCCCCHHHHHHHHCCCCCEEEEEECCCHHHHCCCCCCCCCHHHHHHHCC
NRKPGPQWLEAASQTFAAYRYARNLLSQERFAGVFTTGGYIAAPAVLAARSLNLPAIGHE
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECCCHHHHHHHHHHHCCCCCCCCCC
SNVLPGKVIRYLARWMRSLGLGFAESATYVSGATTRWVGTPVRPEFLISPNPLLDVPVPP
CCCCHHHHHHHHHHHHHHHCCCCCCCCCEECCCCEEECCCCCCCCEEECCCCEEECCCCC
EAPLIVVMGGSQGARAINQMVGECAPGWLERGWWIVHLTGAGEYDAVREGTPDHPAYRIY
CCCEEEEECCCCHHHHHHHHHHHCCCCHHHCCEEEEEEECCCCCCHHHCCCCCCCCEEHH
AFWEKMAPLLSRADLAISRAGAATLSELLVTGTPSLLIPYPFAAEDHQSVNAAALVRAGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCHHHHHHHCC
ALQFSQAALSAPLLDRTVQALLDNPETLARMAASARRLAVPDAARRTADLVRECVRH
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PKPRLLIAASGTGGHIFPALAVAGELSEFEIAWLGVPDRLENKLVPGRYPLHTVALQGL
CCCCEEEEECCCCCCHHHHHHHHCCCCCEEEEEECCCHHHHCCCCCCCCCHHHHHHHCC
NRKPGPQWLEAASQTFAAYRYARNLLSQERFAGVFTTGGYIAAPAVLAARSLNLPAIGHE
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECCCHHHHHHHHHHHCCCCCCCCCC
SNVLPGKVIRYLARWMRSLGLGFAESATYVSGATTRWVGTPVRPEFLISPNPLLDVPVPP
CCCCHHHHHHHHHHHHHHHCCCCCCCCCEECCCCEEECCCCCCCCEEECCCCEEECCCCC
EAPLIVVMGGSQGARAINQMVGECAPGWLERGWWIVHLTGAGEYDAVREGTPDHPAYRIY
CCCEEEEECCCCHHHHHHHHHHHCCCCHHHCCEEEEEEECCCCCCHHHCCCCCCCCEEHH
AFWEKMAPLLSRADLAISRAGAATLSELLVTGTPSLLIPYPFAAEDHQSVNAAALVRAGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCHHHHHHHCC
ALQFSQAALSAPLLDRTVQALLDNPETLARMAASARRLAVPDAARRTADLVRECVRH
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 14621292