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The map label for this gene is typA [H]

Identifier: 37521089

GI number: 37521089

Start: 1638157

End: 1639965

Strand: Reverse

Name: typA [H]

Synonym: gll1520

Alternate gene names: 37521089

Gene position: 1639965-1638157 (Counterclockwise)

Preceding gene: 37521090

Following gene: 37521084

Centisome position: 35.2

GC content: 61.19

Gene sequence:

>1809_bases
ATGGAAACCAACCGTCTGAGTCCGGCTCAGATTCGCAACGTCGCGATTATTGCCCACGTCGACCACGGCAAGACCACCCT
GGTTGACGCTCTGCTCAGGCAGTCCGGGATCTTCCGGGACAACGAAGTGGTGGAAACCTGCGTGATGGACTCTAACGACC
TCGAGCGCGAGCGCGGAATCACGATCCTGGCCAAGAACACGGCGGTAAGCTACCTCGACCATCTCATCAATATCGTGGAC
ACTCCCGGCCACGCCGATTTTGGCGGCGAAGTCGAGCGGGTGCTGGGCATGGTCGAAGGTTGCCTGCTCATCGTCGACGC
CAACGAAGGGCCGATGCCCCAGACGCGCTTCGTGCTCAGAAAGGCACTCGAAAAGGGTCTCAAGCCCATCTTGCTGGTCA
ACAAGATCGACCGGCCCCAGGCCGACCCGCACCGCGCTATCGACAAGGTGCTGGATCTGTTTATCGAACTGGGGGCCGAC
GACGATCAGATCGATTTTCCGGTGCTCTTTGCCTCGGGGCTGTCGGGTTACGCCAAAAACGATCTGGCCGATGAATCCAA
GGACATGCAGCCTCTGTTCGAGGCCATCTTGCGCCACGTTCCGGCGCCGGTGGGCGATCCGACCAAGCCTTTGCAGCTGC
AGGTAACCACTCTCGATTACTCCGAGTACCTGGGCCGCATCGTCGTGGGCAAGATCCACAACGGTTCGATCCGCGCCAAC
GAGACCATCGCCATCGTCAAAGACTCCGGCAAGATCGAGCGGGGCAAGGTGGTCAAACTCTTTGGTTTCGAGGGCCTCAG
CCGCATCGAACTTACCGAGGCTTACGCGGGCAATATCGTGGCGGTGGCGGGCTTTGCCGACGCCAACATCGGCGAGACGC
TCACCAGCGCCGAGCACCCCGAGGCGCTGCCGCTCATCAAAGTCGACGAACCGACCCTGCAGATGACCTTCTCAGTCAAC
GACTCGCCCTTTGCGGGCCAGGAGGGCAAGCACGTCACCTCCCGCAAGCTGCGCGAGCGCCTCTTCAAAGAGCTTGAGAC
CAACGTCTCGCTAAGGGTCGAGGAGACCGATTCGCCCGATCGCTTTTTGGTCTCCGGCCGCGGCGAGCTGCACCTGGGCA
TCTTGATTGAGACGATGCGCCGGGAGGGTTATGAGTTTCAAGTCTCCAAACCCCGAGTGATCTTCCGCGTGGTAGACGGC
CAGGTCTACGAGCCGTTCGAACTATTGGTGCTCGATGTGCCCGACGACGCGGCGGGCGGCTGCATCTCCAACCTCGGCCG
CCGCCGTGCCGAGATGCAGAACATGCAGAGCTTCGGCAACGGCCGCACCCAGCTCGAATTTGTGATCCCCGCTCGCGGGT
TGATGGGCTTTCGCACCGAGTGCCTGCGCCTCACGCGCGGCGAAGGGATCATGAGCCACTCCTTCCTCGACTACCGCTCG
ACGGTGGGCGAAATGGAAACGCTCAGAAACGGTGTGCTCATCGCCTTCGAGGAAGGCGATGCGACGTACTACTCCCTGCA
GAACGCCGAGGACCGGGGCATCTTCTTCATCACCCCCGGCACCCGCGTCTACGCCGGCATGATCATCGGCGAGAACAACC
GCCAGCAGGATCTCGAACTGAACATCTGCAAGACCAAGAAGCTCACCAACATGCGCTCCGCCGGGGGCGAAGAACTGGTG
CAGCTCAAGACGCCTGTGATTATGAGCCTGGAGCGCGCTCTTGAGTACATCAACGACGACGAACTGGTGGAAGTGACTCC
CAAGTCCATCCGCCTGCGCAAGCTGGCCCTCAAAGCCGCCCGCAAGTAG

Upstream 100 bases:

>100_bases
CGTCTCGGCGTCGTAAGCGCAACTGACGGCCTTGGGCGAAGAATGCTAGGATAGGGCTCAAGTCTTAACTTTTGTAAAAC
CACCAGCTTCGGGCCTATCC

Downstream 100 bases:

>100_bases
CCGTCTTCGAGTACATCGCCCGGTCGCTCGCTGCAGCGGCCGGGTTTGCCCTATTCGGGAGCACTGAGTGATATCGCGCC
GTTTGTAGTGTTTATTCCCG

Product: GTP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 602; Mature: 602

Protein sequence:

>602_residues
METNRLSPAQIRNVAIIAHVDHGKTTLVDALLRQSGIFRDNEVVETCVMDSNDLERERGITILAKNTAVSYLDHLINIVD
TPGHADFGGEVERVLGMVEGCLLIVDANEGPMPQTRFVLRKALEKGLKPILLVNKIDRPQADPHRAIDKVLDLFIELGAD
DDQIDFPVLFASGLSGYAKNDLADESKDMQPLFEAILRHVPAPVGDPTKPLQLQVTTLDYSEYLGRIVVGKIHNGSIRAN
ETIAIVKDSGKIERGKVVKLFGFEGLSRIELTEAYAGNIVAVAGFADANIGETLTSAEHPEALPLIKVDEPTLQMTFSVN
DSPFAGQEGKHVTSRKLRERLFKELETNVSLRVEETDSPDRFLVSGRGELHLGILIETMRREGYEFQVSKPRVIFRVVDG
QVYEPFELLVLDVPDDAAGGCISNLGRRRAEMQNMQSFGNGRTQLEFVIPARGLMGFRTECLRLTRGEGIMSHSFLDYRS
TVGEMETLRNGVLIAFEEGDATYYSLQNAEDRGIFFITPGTRVYAGMIIGENNRQQDLELNICKTKKLTNMRSAGGEELV
QLKTPVIMSLERALEYINDDELVEVTPKSIRLRKLALKAARK

Sequences:

>Translated_602_residues
METNRLSPAQIRNVAIIAHVDHGKTTLVDALLRQSGIFRDNEVVETCVMDSNDLERERGITILAKNTAVSYLDHLINIVD
TPGHADFGGEVERVLGMVEGCLLIVDANEGPMPQTRFVLRKALEKGLKPILLVNKIDRPQADPHRAIDKVLDLFIELGAD
DDQIDFPVLFASGLSGYAKNDLADESKDMQPLFEAILRHVPAPVGDPTKPLQLQVTTLDYSEYLGRIVVGKIHNGSIRAN
ETIAIVKDSGKIERGKVVKLFGFEGLSRIELTEAYAGNIVAVAGFADANIGETLTSAEHPEALPLIKVDEPTLQMTFSVN
DSPFAGQEGKHVTSRKLRERLFKELETNVSLRVEETDSPDRFLVSGRGELHLGILIETMRREGYEFQVSKPRVIFRVVDG
QVYEPFELLVLDVPDDAAGGCISNLGRRRAEMQNMQSFGNGRTQLEFVIPARGLMGFRTECLRLTRGEGIMSHSFLDYRS
TVGEMETLRNGVLIAFEEGDATYYSLQNAEDRGIFFITPGTRVYAGMIIGENNRQQDLELNICKTKKLTNMRSAGGEELV
QLKTPVIMSLERALEYINDDELVEVTPKSIRLRKLALKAARK
>Mature_602_residues
METNRLSPAQIRNVAIIAHVDHGKTTLVDALLRQSGIFRDNEVVETCVMDSNDLERERGITILAKNTAVSYLDHLINIVD
TPGHADFGGEVERVLGMVEGCLLIVDANEGPMPQTRFVLRKALEKGLKPILLVNKIDRPQADPHRAIDKVLDLFIELGAD
DDQIDFPVLFASGLSGYAKNDLADESKDMQPLFEAILRHVPAPVGDPTKPLQLQVTTLDYSEYLGRIVVGKIHNGSIRAN
ETIAIVKDSGKIERGKVVKLFGFEGLSRIELTEAYAGNIVAVAGFADANIGETLTSAEHPEALPLIKVDEPTLQMTFSVN
DSPFAGQEGKHVTSRKLRERLFKELETNVSLRVEETDSPDRFLVSGRGELHLGILIETMRREGYEFQVSKPRVIFRVVDG
QVYEPFELLVLDVPDDAAGGCISNLGRRRAEMQNMQSFGNGRTQLEFVIPARGLMGFRTECLRLTRGEGIMSHSFLDYRS
TVGEMETLRNGVLIAFEEGDATYYSLQNAEDRGIFFITPGTRVYAGMIIGENNRQQDLELNICKTKKLTNMRSAGGEELV
QLKTPVIMSLERALEYINDDELVEVTPKSIRLRKLALKAARK

Specific function: Not known; probably interacts with the ribosomes in a GTP dependent manner [H]

COG id: COG1217

COG function: function code T; Predicted membrane GTPase involved in stress response

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding elongation factor family. TypA subfamily [H]

Homologues:

Organism=Homo sapiens, GI157426893, Length=539, Percent_Identity=27.0871985157699, Blast_Score=140, Evalue=4e-33,
Organism=Homo sapiens, GI94966754, Length=134, Percent_Identity=44.0298507462687, Blast_Score=126, Evalue=5e-29,
Organism=Homo sapiens, GI4503483, Length=148, Percent_Identity=41.2162162162162, Blast_Score=109, Evalue=6e-24,
Organism=Homo sapiens, GI18390331, Length=146, Percent_Identity=41.7808219178082, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI34147630, Length=246, Percent_Identity=31.7073170731707, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI310132016, Length=112, Percent_Identity=41.0714285714286, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI310110807, Length=112, Percent_Identity=41.0714285714286, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI310123363, Length=112, Percent_Identity=41.0714285714286, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI25306287, Length=144, Percent_Identity=36.8055555555556, Blast_Score=93, Evalue=7e-19,
Organism=Homo sapiens, GI19923640, Length=144, Percent_Identity=36.8055555555556, Blast_Score=93, Evalue=7e-19,
Organism=Homo sapiens, GI25306283, Length=144, Percent_Identity=36.8055555555556, Blast_Score=93, Evalue=7e-19,
Organism=Homo sapiens, GI217272892, Length=155, Percent_Identity=34.1935483870968, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI217272894, Length=155, Percent_Identity=34.1935483870968, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI94966752, Length=130, Percent_Identity=33.8461538461538, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI53729339, Length=286, Percent_Identity=26.5734265734266, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI53729337, Length=286, Percent_Identity=26.5734265734266, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI48994988, Length=589, Percent_Identity=53.4804753820034, Blast_Score=635, Evalue=0.0,
Organism=Escherichia coli, GI1788922, Length=540, Percent_Identity=29.8148148148148, Blast_Score=160, Evalue=2e-40,
Organism=Escherichia coli, GI1789738, Length=156, Percent_Identity=37.8205128205128, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1790835, Length=415, Percent_Identity=24.0963855421687, Blast_Score=87, Evalue=4e-18,
Organism=Escherichia coli, GI1789737, Length=235, Percent_Identity=27.6595744680851, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1790412, Length=235, Percent_Identity=27.6595744680851, Blast_Score=71, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17557151, Length=318, Percent_Identity=31.4465408805031, Blast_Score=132, Evalue=6e-31,
Organism=Caenorhabditis elegans, GI17556745, Length=458, Percent_Identity=25.5458515283843, Blast_Score=113, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI17506493, Length=217, Percent_Identity=33.6405529953917, Blast_Score=110, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI71988811, Length=134, Percent_Identity=41.7910447761194, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI71988819, Length=134, Percent_Identity=41.7910447761194, Blast_Score=103, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17533571, Length=501, Percent_Identity=26.9461077844311, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17552882, Length=188, Percent_Identity=32.4468085106383, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17556456, Length=172, Percent_Identity=33.7209302325581, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71994658, Length=275, Percent_Identity=27.2727272727273, Blast_Score=69, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6323320, Length=522, Percent_Identity=28.9272030651341, Blast_Score=151, Evalue=2e-37,
Organism=Saccharomyces cerevisiae, GI6324707, Length=203, Percent_Identity=35.4679802955665, Blast_Score=113, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6320593, Length=203, Percent_Identity=35.4679802955665, Blast_Score=113, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6323098, Length=179, Percent_Identity=39.1061452513966, Blast_Score=100, Evalue=5e-22,
Organism=Saccharomyces cerevisiae, GI6324761, Length=274, Percent_Identity=28.4671532846715, Blast_Score=96, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6324166, Length=147, Percent_Identity=39.4557823129252, Blast_Score=96, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6322359, Length=158, Percent_Identity=34.8101265822785, Blast_Score=94, Evalue=6e-20,
Organism=Drosophila melanogaster, GI78706572, Length=506, Percent_Identity=25.296442687747, Blast_Score=120, Evalue=4e-27,
Organism=Drosophila melanogaster, GI28574573, Length=188, Percent_Identity=37.7659574468085, Blast_Score=112, Evalue=7e-25,
Organism=Drosophila melanogaster, GI24585711, Length=150, Percent_Identity=41.3333333333333, Blast_Score=108, Evalue=8e-24,
Organism=Drosophila melanogaster, GI24585713, Length=150, Percent_Identity=41.3333333333333, Blast_Score=108, Evalue=8e-24,
Organism=Drosophila melanogaster, GI24585709, Length=150, Percent_Identity=41.3333333333333, Blast_Score=108, Evalue=9e-24,
Organism=Drosophila melanogaster, GI24582462, Length=146, Percent_Identity=39.041095890411, Blast_Score=101, Evalue=2e-21,
Organism=Drosophila melanogaster, GI21357743, Length=194, Percent_Identity=34.5360824742268, Blast_Score=97, Evalue=4e-20,
Organism=Drosophila melanogaster, GI221458488, Length=150, Percent_Identity=40, Blast_Score=94, Evalue=4e-19,
Organism=Drosophila melanogaster, GI281363316, Length=271, Percent_Identity=28.4132841328413, Blast_Score=88, Evalue=2e-17,
Organism=Drosophila melanogaster, GI17864358, Length=271, Percent_Identity=28.4132841328413, Blast_Score=88, Evalue=2e-17,
Organism=Drosophila melanogaster, GI19921738, Length=233, Percent_Identity=30.0429184549356, Blast_Score=86, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR000795
- InterPro:   IPR005225
- InterPro:   IPR000640
- InterPro:   IPR004161
- InterPro:   IPR009000
- InterPro:   IPR006298 [H]

Pfam domain/function: PF00679 EFG_C; PF00009 GTP_EFTU; PF03144 GTP_EFTU_D2 [H]

EC number: NA

Molecular weight: Translated: 66904; Mature: 66904

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: PS00301 EFACTOR_GTP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METNRLSPAQIRNVAIIAHVDHGKTTLVDALLRQSGIFRDNEVVETCVMDSNDLERERGI
CCCCCCCHHHHCEEEEEEEECCCHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCHHHCCE
TILAKNTAVSYLDHLINIVDTPGHADFGGEVERVLGMVEGCLLIVDANEGPMPQTRFVLR
EEEECCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHH
KALEKGLKPILLVNKIDRPQADPHRAIDKVLDLFIELGADDDQIDFPVLFASGLSGYAKN
HHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCCC
DLADESKDMQPLFEAILRHVPAPVGDPTKPLQLQVTTLDYSEYLGRIVVGKIHNGSIRAN
CCCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECHHHHCCEEEEEEEECCCEECC
ETIAIVKDSGKIERGKVVKLFGFEGLSRIELTEAYAGNIVAVAGFADANIGETLTSAEHP
CEEEEEECCCCCCCCCEEEEECCCCCCEEEEEHHCCCCEEEEEECCCCCCCHHHHCCCCC
EALPLIKVDEPTLQMTFSVNDSPFAGQEGKHVTSRKLRERLFKELETNVSLRVEETDSPD
CCCCEEEECCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCC
RFLVSGRGELHLGILIETMRREGYEFQVSKPRVIFRVVDGQVYEPFELLVLDVPDDAAGG
EEEEECCCCEEEHHHHHHHHHCCCEEEECCCEEEEEEECCCCCCCEEEEEEECCCCCCCH
CISNLGRRRAEMQNMQSFGNGRTQLEFVIPARGLMGFRTECLRLTRGEGIMSHSFLDYRS
HHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCCHHHHHHHHHH
TVGEMETLRNGVLIAFEEGDATYYSLQNAEDRGIFFITPGTRVYAGMIIGENNRQQDLEL
HHHHHHHHCCCEEEEEECCCCEEEEECCCCCCCEEEECCCCEEEEEEEEECCCCCCCCEE
NICKTKKLTNMRSAGGEELVQLKTPVIMSLERALEYINDDELVEVTPKSIRLRKLALKAA
EEECCHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHH
RK
CC
>Mature Secondary Structure
METNRLSPAQIRNVAIIAHVDHGKTTLVDALLRQSGIFRDNEVVETCVMDSNDLERERGI
CCCCCCCHHHHCEEEEEEEECCCHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCHHHCCE
TILAKNTAVSYLDHLINIVDTPGHADFGGEVERVLGMVEGCLLIVDANEGPMPQTRFVLR
EEEECCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHH
KALEKGLKPILLVNKIDRPQADPHRAIDKVLDLFIELGADDDQIDFPVLFASGLSGYAKN
HHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCCC
DLADESKDMQPLFEAILRHVPAPVGDPTKPLQLQVTTLDYSEYLGRIVVGKIHNGSIRAN
CCCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECHHHHCCEEEEEEEECCCEECC
ETIAIVKDSGKIERGKVVKLFGFEGLSRIELTEAYAGNIVAVAGFADANIGETLTSAEHP
CEEEEEECCCCCCCCCEEEEECCCCCCEEEEEHHCCCCEEEEEECCCCCCCHHHHCCCCC
EALPLIKVDEPTLQMTFSVNDSPFAGQEGKHVTSRKLRERLFKELETNVSLRVEETDSPD
CCCCEEEECCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCC
RFLVSGRGELHLGILIETMRREGYEFQVSKPRVIFRVVDGQVYEPFELLVLDVPDDAAGG
EEEEECCCCEEEHHHHHHHHHCCCEEEECCCEEEEEEECCCCCCCEEEEEEECCCCCCCH
CISNLGRRRAEMQNMQSFGNGRTQLEFVIPARGLMGFRTECLRLTRGEGIMSHSFLDYRS
HHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCCHHHHHHHHHH
TVGEMETLRNGVLIAFEEGDATYYSLQNAEDRGIFFITPGTRVYAGMIIGENNRQQDLEL
HHHHHHHHCCCEEEEEECCCCEEEEECCCCCCCEEEECCCCEEEEEEEEECCCCCCCCEE
NICKTKKLTNMRSAGGEELVQLKTPVIMSLERALEYINDDELVEVTPKSIRLRKLALKAA
EEECCHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHH
RK
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]