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The map label for this gene is murI

Identifier: 37521065

GI number: 37521065

Start: 1608749

End: 1609546

Strand: Reverse

Name: murI

Synonym: gll1496

Alternate gene names: 37521065

Gene position: 1609546-1608749 (Counterclockwise)

Preceding gene: 37521066

Following gene: 37521064

Centisome position: 34.55

GC content: 68.67

Gene sequence:

>798_bases
ATGGTTTTGGGCCTATTTGACAGCGGGCTGGGTGGTCTGACGGTGCTGCGGGAAATCGCCCGTAGGCTGCCCGCACAGCC
GGTGATCTACTTTGCCGACACGGCCCGCCTGCCCTACGGCTCTCGCACCCCGGCCGAAATCTGCCGGTACGTGCGCGAGA
TCTTGCACTGGTTCGAACAGCAGGGAGTCCAGCGCGTGCTGATGGCCTGCAACACCAGTTCGGCCCTCGCGTTGCCGGTG
GTCGCGTCGGAATATGCCCTGAAAGTCGGTGGGCTAATCGCCCCGGCCGCCCGCGCCGCCGCCCGCCGAGGCCGGCGCAT
CGGTGTGATCGCCACCGCCGCCACGGTTCAAAGCCATGCCTACACCCGCGCCATCCAGGCGCTCACCCCCCGGGCGCAAG
TATGGGAAGTTGCCTGCCCAGAATTTGTGCCGCTCGTCGAAGGCGGCCGGCTGCTGGGCGAGGAGGTGCGCTCGGTGGCC
CGCCGCTACCTGGCGCCGCTGGTAGAACAGCGCATCGACACCCTCGTCTATGGCTGCACCCACTATCCGTACCTGGCTCC
GGTGATTGGCGATCTGCTCCCGGCCAGTGTGCGGTGCGTCGACCCGGCGGTGGCGGCGGTGGCCGAACTGGCGGCGGCAC
TGCCGCCCTCACGGCGGTTGGAGACCCGGGCTGCCTGTCACTTTTTCGTCTCCGGCGATCCGGTGCGCTTTGCGCAGGCG
GCCTACCCCTGGCTCGACTACTATCCGCAGGTGCAGGCGGTCGCCCTGCCGCCGCTGCCGGCCGCTCAGACAAACTAG

Upstream 100 bases:

>100_bases
CCTGGGGAGTGCACCCTCATCGACCTGCGCTCTTGAGGACAGTTCTAGTCCGGTGCCCTTCCATGGGACACTCGAAAACA
GTGTGACGAGTGCGTAGGGT

Downstream 100 bases:

>100_bases
AGCGCTTTCAGGTGTCAGGTGTCAGGATTGCAACCGTTGTCCACTGGGGTTTACAGTCAGCCTGCCGGTGTCTGGGCAAC
CAAAAAACCGCTCCAGTCTC

Product: glutamate racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 265; Mature: 265

Protein sequence:

>265_residues
MVLGLFDSGLGGLTVLREIARRLPAQPVIYFADTARLPYGSRTPAEICRYVREILHWFEQQGVQRVLMACNTSSALALPV
VASEYALKVGGLIAPAARAAARRGRRIGVIATAATVQSHAYTRAIQALTPRAQVWEVACPEFVPLVEGGRLLGEEVRSVA
RRYLAPLVEQRIDTLVYGCTHYPYLAPVIGDLLPASVRCVDPAVAAVAELAAALPPSRRLETRAACHFFVSGDPVRFAQA
AYPWLDYYPQVQAVALPPLPAAQTN

Sequences:

>Translated_265_residues
MVLGLFDSGLGGLTVLREIARRLPAQPVIYFADTARLPYGSRTPAEICRYVREILHWFEQQGVQRVLMACNTSSALALPV
VASEYALKVGGLIAPAARAAARRGRRIGVIATAATVQSHAYTRAIQALTPRAQVWEVACPEFVPLVEGGRLLGEEVRSVA
RRYLAPLVEQRIDTLVYGCTHYPYLAPVIGDLLPASVRCVDPAVAAVAELAAALPPSRRLETRAACHFFVSGDPVRFAQA
AYPWLDYYPQVQAVALPPLPAAQTN
>Mature_265_residues
MVLGLFDSGLGGLTVLREIARRLPAQPVIYFADTARLPYGSRTPAEICRYVREILHWFEQQGVQRVLMACNTSSALALPV
VASEYALKVGGLIAPAARAAARRGRRIGVIATAATVQSHAYTRAIQALTPRAQVWEVACPEFVPLVEGGRLLGEEVRSVA
RRYLAPLVEQRIDTLVYGCTHYPYLAPVIGDLLPASVRCVDPAVAAVAELAAALPPSRRLETRAACHFFVSGDPVRFAQA
AYPWLDYYPQVQAVALPPLPAAQTN

Specific function: Provides the (R)-glutamate required for cell wall biosynthesis

COG id: COG0796

COG function: function code M; Glutamate racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate/glutamate racemases family

Homologues:

Organism=Escherichia coli, GI87082355, Length=207, Percent_Identity=33.8164251207729, Blast_Score=91, Evalue=9e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURI_GLOVI (Q7NKI2)

Other databases:

- EMBL:   BA000045
- RefSeq:   NP_924442.1
- HSSP:   P56868
- ProteinModelPortal:   Q7NKI2
- SMR:   Q7NKI2
- GeneID:   2598674
- GenomeReviews:   BA000045_GR
- KEGG:   gvi:gll1496
- NMPDR:   fig|251221.1.peg.1496
- HOGENOM:   HBG645102
- OMA:   AILGCTH
- ProtClustDB:   PRK00865
- BioCyc:   GVIO251221:GLL1496-MONOMER
- BRENDA:   5.1.1.3
- HAMAP:   MF_00258
- InterPro:   IPR015942
- InterPro:   IPR001920
- InterPro:   IPR018187
- InterPro:   IPR004391
- Gene3D:   G3DSA:3.40.50.1860
- TIGRFAMs:   TIGR00067

Pfam domain/function: PF01177 Asp_Glu_race; SSF53681 Asp/Glu_race

EC number: =5.1.1.3

Molecular weight: Translated: 28728; Mature: 28728

Theoretical pI: Translated: 8.97; Mature: 8.97

Prosite motif: PS00923 ASP_GLU_RACEMASE_1; PS00924 ASP_GLU_RACEMASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLGLFDSGLGGLTVLREIARRLPAQPVIYFADTARLPYGSRTPAEICRYVREILHWFEQ
CEEEECCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHH
QGVQRVLMACNTSSALALPVVASEYALKVGGLIAPAARAAARRGRRIGVIATAATVQSHA
HHHHHHHHHHCCCCCEEHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEEEEEHHHHHHHHH
YTRAIQALTPRAQVWEVACPEFVPLVEGGRLLGEEVRSVARRYLAPLVEQRIDTLVYGCT
HHHHHHHHCCHHHHHHHCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
HYPYLAPVIGDLLPASVRCVDPAVAAVAELAAALPPSRRLETRAACHFFVSGDPVRFAQA
CCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHEEEEECCCCHHHHHH
AYPWLDYYPQVQAVALPPLPAAQTN
HCCHHHHCCCCEEEECCCCCCCCCC
>Mature Secondary Structure
MVLGLFDSGLGGLTVLREIARRLPAQPVIYFADTARLPYGSRTPAEICRYVREILHWFEQ
CEEEECCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHH
QGVQRVLMACNTSSALALPVVASEYALKVGGLIAPAARAAARRGRRIGVIATAATVQSHA
HHHHHHHHHHCCCCCEEHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEEEEEHHHHHHHHH
YTRAIQALTPRAQVWEVACPEFVPLVEGGRLLGEEVRSVARRYLAPLVEQRIDTLVYGCT
HHHHHHHHCCHHHHHHHCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
HYPYLAPVIGDLLPASVRCVDPAVAAVAELAAALPPSRRLETRAACHFFVSGDPVRFAQA
CCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHEEEEECCCCHHHHHH
AYPWLDYYPQVQAVALPPLPAAQTN
HCCHHHHCCCCEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14621292