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The map label for this gene is gph [C]

Identifier: 37520921

GI number: 37520921

Start: 1446077

End: 1446727

Strand: Reverse

Name: gph [C]

Synonym: gll1352

Alternate gene names: 37520921

Gene position: 1446727-1446077 (Counterclockwise)

Preceding gene: 37520922

Following gene: 37520917

Centisome position: 31.05

GC content: 61.6

Gene sequence:

>651_bases
GTGAAGGCGGTGCTCTTTGACGCCGTCGGTACTCTGTTCGGAGTACGCGGCTCGGTGGGCGAAATTTACAGCGCCATCGC
CCGGACTTTCGGGGTCAAAAGCGATCCCGAAGCGATCGAAAAGCACTTTTGCGTGGCCTTCGCCGCCCGTCGGTCCCCGA
ACGCCGATGCGCGGCCCTGGTGGCGCTCCGTGGTGGCCCAGACGTTTACCGACACCGATTTTCCCGATTTCGAGGCTTAC
TTCGAGCGGGTCTGGAGTCACTTCGCCACTGCCGAGCCCTGGTTTGTCTACCCGGAGACCGTCGGTGTGCTCGCCGAACT
GCGTTCGCGCAGTCTGGTCCTCGCAGTGGTCTCCAACTTCGACGAGCGGCTTTACCCGGTTCTAGAAGCGCTTGGGCTAC
GCGGTTATTTTCAGGTGGTGGCCATCTCTACCGAGGTGGGCCACGCCAAGCCCGACCCGCGCCTTTTTACCCACGCTCTG
CAGCGGCTGGGTTGTTCAGTCGACGAAGCCATCCACGTCGGCGACTCGACCGAGGATGTGATCGGCGCCAAAGCAGCCGG
TATCCGAGTCTTCAAAGTCGACCGCTCCGGAGCGGCCGGTGCCGACACTATCAATTCGCTCGCCAGGCTTTTGGAGATGG
ATTATTTCTGA

Upstream 100 bases:

>100_bases
CACTTTTGAGGGGTGACGACGGCCAGGAAAGCTGGATCTTCGAAGTGCGCTCGGCACCCCTGGAGGCGACCTGGCTGCGG
GGTACCCTGGGTGCCGGTCA

Downstream 100 bases:

>100_bases
GCCAGCCAGGTGATCAGATCTGCAAGTTCATGGAAATCCAGCAAAGCTTCGCTGAGCGCTTCAAGTTCGGCGACTGAAAG
TGTGCGCACCTGTTCGATGG

Product: hypothetical protein

Products: Glycolate; Phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 216; Mature: 216

Protein sequence:

>216_residues
MKAVLFDAVGTLFGVRGSVGEIYSAIARTFGVKSDPEAIEKHFCVAFAARRSPNADARPWWRSVVAQTFTDTDFPDFEAY
FERVWSHFATAEPWFVYPETVGVLAELRSRSLVLAVVSNFDERLYPVLEALGLRGYFQVVAISTEVGHAKPDPRLFTHAL
QRLGCSVDEAIHVGDSTEDVIGAKAAGIRVFKVDRSGAAGADTINSLARLLEMDYF

Sequences:

>Translated_216_residues
MKAVLFDAVGTLFGVRGSVGEIYSAIARTFGVKSDPEAIEKHFCVAFAARRSPNADARPWWRSVVAQTFTDTDFPDFEAY
FERVWSHFATAEPWFVYPETVGVLAELRSRSLVLAVVSNFDERLYPVLEALGLRGYFQVVAISTEVGHAKPDPRLFTHAL
QRLGCSVDEAIHVGDSTEDVIGAKAAGIRVFKVDRSGAAGADTINSLARLLEMDYF
>Mature_216_residues
MKAVLFDAVGTLFGVRGSVGEIYSAIARTFGVKSDPEAIEKHFCVAFAARRSPNADARPWWRSVVAQTFTDTDFPDFEAY
FERVWSHFATAEPWFVYPETVGVLAELRSRSLVLAVVSNFDERLYPVLEALGLRGYFQVVAISTEVGHAKPDPRLFTHAL
QRLGCSVDEAIHVGDSTEDVIGAKAAGIRVFKVDRSGAAGADTINSLARLLEMDYF

Specific function: Unknown

COG id: COG1011

COG function: function code R; Predicted hydrolase (HAD superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily [H]

Homologues:

Organism=Homo sapiens, GI13654294, Length=205, Percent_Identity=36.0975609756098, Blast_Score=91, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI17553988, Length=231, Percent_Identity=29.8701298701299, Blast_Score=100, Evalue=6e-22,
Organism=Saccharomyces cerevisiae, GI6323778, Length=237, Percent_Identity=27.0042194092827, Blast_Score=91, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24639695, Length=226, Percent_Identity=30.5309734513274, Blast_Score=87, Evalue=7e-18,
Organism=Drosophila melanogaster, GI19923000, Length=208, Percent_Identity=27.8846153846154, Blast_Score=86, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR011950
- InterPro:   IPR006439
- InterPro:   IPR005833 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: 3.1.3.18 [C]

Molecular weight: Translated: 23811; Mature: 23811

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAVLFDAVGTLFGVRGSVGEIYSAIARTFGVKSDPEAIEKHFCVAFAARRSPNADARPW
CCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCHH
WRSVVAQTFTDTDFPDFEAYFERVWSHFATAEPWFVYPETVGVLAELRSRSLVLAVVSNF
HHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCEECHHHHHHHHHHHHCHHHHHHHHHH
DERLYPVLEALGLRGYFQVVAISTEVGHAKPDPRLFTHALQRLGCSVDEAIHVGDSTEDV
HHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHCCCHHHHEECCCCCHHH
IGAKAAGIRVFKVDRSGAAGADTINSLARLLEMDYF
HHHHHCCEEEEEECCCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKAVLFDAVGTLFGVRGSVGEIYSAIARTFGVKSDPEAIEKHFCVAFAARRSPNADARPW
CCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCHH
WRSVVAQTFTDTDFPDFEAYFERVWSHFATAEPWFVYPETVGVLAELRSRSLVLAVVSNF
HHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCEECHHHHHHHHHHHHCHHHHHHHHHH
DERLYPVLEALGLRGYFQVVAISTEVGHAKPDPRLFTHALQRLGCSVDEAIHVGDSTEDV
HHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHCCCHHHHEECCCCCHHH
IGAKAAGIRVFKVDRSGAAGADTINSLARLLEMDYF
HHHHHCCEEEEEECCCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Mg2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): 0.57 {phosphoglycolate}} [C]

Substrates: D-Glycerate 2-phosphatelyc; H2O [C]

Specific reaction: D-Glycerate 2-phosphatelyc + H2O --> Glycolate + Phosphate [C]

General reaction: Additional information:

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]