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The map label for this gene is 37520844

Identifier: 37520844

GI number: 37520844

Start: 1350561

End: 1351484

Strand: Reverse

Name: 37520844

Synonym: gll1275

Alternate gene names: NA

Gene position: 1351484-1350561 (Counterclockwise)

Preceding gene: 37520845

Following gene: 37520843

Centisome position: 29.01

GC content: 67.86

Gene sequence:

>924_bases
GTGCTGCCGGTCATCTACACCGATCGTTTCCTCGAACATCGCACCGGGGCTATGCACCCCGAGCGGCCCCAGCGGCTTGC
GGCAATTGTCGAGCGCCTGCGCCGCTCGCCGCTCGCTCCGTCCCTTGCCTGGCAGGAACCGCGCCAGGCCACCCGCGAGC
AATTGCTCTGGGTCCACAGCGCCGAACTGGTCGAGACGGTCGAACAGGTCTGCAGGGCCGGCGGCGGTTCGCTCGATCCT
GACACGACGGTGAGTGCCGAGAGCTTCGAGGTGGCTTCGCTCGCGGCGGGCGGTTGGCTGGACGGTGTCGATGCGGTGAT
CCGCACGGGCGAACCCGCCTGGGTGCTCGCCCGCCCCCCCGGCCACCACGCCGAGCGCGGGCAGGCGATGGGATTTTGCG
TGTTTGCCAACGCCGCCCTGGCTGCCCATTACGCGTTGCGCGTGCACGGCCGGACGCGCGTCGCGGTGCTCGACTGGGAC
GTGCACCACGGCAACGGCACCCAGCAACTGCTTTGGGAAGAATCGCGCCTGGCGTATATCTCGCTGCACCAGTCACCCCA
CTACCCGGGCACCGGCCACAGCCACGAACGCGGCGCGGCGGATAACGTTCTCAACGTGCCGCTACCGGCCGGGTGTGCCC
GCAAAGAGTACCAGCAGGCGCTCGACACGCTGGTCTGGCCGTTTATCGAACGCTTCGATCCGGAGTTATTGATCGTCAGC
GCCGGTTTTGACGGCCACATCGACGATCCGCTCGCCGAGATGGCTTTGCGGGCCTCGGACTACGGCGATTTTGCCCGCCA
GGCCCTGGCGCGCACTCGCCGGGTGCTCTTCGGCCTCGAAGGCGGCTACGACCTGGACGGCCTGGCCGAATCGGTTTTCG
CGGTCACCGAAGCCTGTCTGTCGGTGCGAACCCGTCAGGTATAG

Upstream 100 bases:

>100_bases
ACGACCTTTCGGGTGGGGGCGCGCTTTGAGATTGGCGGCTGAGGCGGCGAGCCGACCGTTATAATACCGTCCTGGCCTGT
TCGTTCCAGGTAAGGACACT

Downstream 100 bases:

>100_bases
GGCATTCAGCCGACCCGGCGCCCGGTCACTCAACAGCAGAAGGATCTACCTCCGTGAAGCTCGTCAAAGATCAACTGGTC
TGCCTGCGTCTCGACGACGC

Product: histone deacetylase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MLPVIYTDRFLEHRTGAMHPERPQRLAAIVERLRRSPLAPSLAWQEPRQATREQLLWVHSAELVETVEQVCRAGGGSLDP
DTTVSAESFEVASLAAGGWLDGVDAVIRTGEPAWVLARPPGHHAERGQAMGFCVFANAALAAHYALRVHGRTRVAVLDWD
VHHGNGTQQLLWEESRLAYISLHQSPHYPGTGHSHERGAADNVLNVPLPAGCARKEYQQALDTLVWPFIERFDPELLIVS
AGFDGHIDDPLAEMALRASDYGDFARQALARTRRVLFGLEGGYDLDGLAESVFAVTEACLSVRTRQV

Sequences:

>Translated_307_residues
MLPVIYTDRFLEHRTGAMHPERPQRLAAIVERLRRSPLAPSLAWQEPRQATREQLLWVHSAELVETVEQVCRAGGGSLDP
DTTVSAESFEVASLAAGGWLDGVDAVIRTGEPAWVLARPPGHHAERGQAMGFCVFANAALAAHYALRVHGRTRVAVLDWD
VHHGNGTQQLLWEESRLAYISLHQSPHYPGTGHSHERGAADNVLNVPLPAGCARKEYQQALDTLVWPFIERFDPELLIVS
AGFDGHIDDPLAEMALRASDYGDFARQALARTRRVLFGLEGGYDLDGLAESVFAVTEACLSVRTRQV
>Mature_307_residues
MLPVIYTDRFLEHRTGAMHPERPQRLAAIVERLRRSPLAPSLAWQEPRQATREQLLWVHSAELVETVEQVCRAGGGSLDP
DTTVSAESFEVASLAAGGWLDGVDAVIRTGEPAWVLARPPGHHAERGQAMGFCVFANAALAAHYALRVHGRTRVAVLDWD
VHHGNGTQQLLWEESRLAYISLHQSPHYPGTGHSHERGAADNVLNVPLPAGCARKEYQQALDTLVWPFIERFDPELLIVS
AGFDGHIDDPLAEMALRASDYGDFARQALARTRRVLFGLEGGYDLDGLAESVFAVTEACLSVRTRQV

Specific function: Putative deacetylase [H]

COG id: COG0123

COG function: function code BQ; Deacetylases, including yeast histone deacetylase and acetoin utilization protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone deacetylase family [H]

Homologues:

Organism=Homo sapiens, GI20070354, Length=308, Percent_Identity=38.961038961039, Blast_Score=156, Evalue=2e-38,
Organism=Homo sapiens, GI13128864, Length=316, Percent_Identity=34.1772151898734, Blast_Score=148, Evalue=5e-36,
Organism=Homo sapiens, GI62750349, Length=342, Percent_Identity=31.8713450292398, Blast_Score=136, Evalue=3e-32,
Organism=Homo sapiens, GI62750347, Length=342, Percent_Identity=31.8713450292398, Blast_Score=135, Evalue=3e-32,
Organism=Homo sapiens, GI17158039, Length=344, Percent_Identity=30.5232558139535, Blast_Score=135, Evalue=4e-32,
Organism=Homo sapiens, GI153085395, Length=343, Percent_Identity=32.3615160349854, Blast_Score=135, Evalue=4e-32,
Organism=Homo sapiens, GI30795204, Length=344, Percent_Identity=30.5232558139535, Blast_Score=135, Evalue=5e-32,
Organism=Homo sapiens, GI30795202, Length=344, Percent_Identity=30.5232558139535, Blast_Score=135, Evalue=5e-32,
Organism=Homo sapiens, GI148539870, Length=343, Percent_Identity=30.6122448979592, Blast_Score=127, Evalue=9e-30,
Organism=Homo sapiens, GI169234807, Length=343, Percent_Identity=30.6122448979592, Blast_Score=127, Evalue=1e-29,
Organism=Homo sapiens, GI226529806, Length=306, Percent_Identity=34.9673202614379, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI13128862, Length=288, Percent_Identity=24.6527777777778, Blast_Score=92, Evalue=8e-19,
Organism=Homo sapiens, GI293336691, Length=257, Percent_Identity=26.4591439688716, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI13128860, Length=259, Percent_Identity=25.8687258687259, Blast_Score=85, Evalue=8e-17,
Organism=Homo sapiens, GI8923769, Length=288, Percent_Identity=23.2638888888889, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI262073088, Length=174, Percent_Identity=27.5862068965517, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI217272877, Length=298, Percent_Identity=23.8255033557047, Blast_Score=69, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17540334, Length=301, Percent_Identity=34.21926910299, Blast_Score=168, Evalue=3e-42,
Organism=Caenorhabditis elegans, GI17540332, Length=301, Percent_Identity=35.2159468438538, Blast_Score=164, Evalue=6e-41,
Organism=Caenorhabditis elegans, GI193206283, Length=301, Percent_Identity=35.2159468438538, Blast_Score=164, Evalue=6e-41,
Organism=Caenorhabditis elegans, GI17537347, Length=292, Percent_Identity=33.9041095890411, Blast_Score=145, Evalue=3e-35,
Organism=Caenorhabditis elegans, GI193209491, Length=243, Percent_Identity=34.9794238683128, Blast_Score=130, Evalue=7e-31,
Organism=Caenorhabditis elegans, GI25154020, Length=319, Percent_Identity=29.4670846394984, Blast_Score=127, Evalue=8e-30,
Organism=Caenorhabditis elegans, GI25154022, Length=320, Percent_Identity=28.75, Blast_Score=120, Evalue=8e-28,
Organism=Caenorhabditis elegans, GI17534739, Length=305, Percent_Identity=24.9180327868852, Blast_Score=94, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI17508561, Length=297, Percent_Identity=24.9158249158249, Blast_Score=91, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17561978, Length=242, Percent_Identity=27.2727272727273, Blast_Score=87, Evalue=8e-18,
Organism=Saccharomyces cerevisiae, GI6324307, Length=314, Percent_Identity=32.484076433121, Blast_Score=151, Evalue=1e-37,
Organism=Saccharomyces cerevisiae, GI6321244, Length=293, Percent_Identity=25.5972696245734, Blast_Score=101, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6323999, Length=290, Percent_Identity=23.1034482758621, Blast_Score=89, Evalue=8e-19,
Organism=Saccharomyces cerevisiae, GI6325141, Length=360, Percent_Identity=23.3333333333333, Blast_Score=83, Evalue=5e-17,
Organism=Saccharomyces cerevisiae, GI6325325, Length=137, Percent_Identity=32.8467153284672, Blast_Score=83, Evalue=6e-17,
Organism=Drosophila melanogaster, GI281360899, Length=304, Percent_Identity=34.2105263157895, Blast_Score=164, Evalue=8e-41,
Organism=Drosophila melanogaster, GI24642142, Length=304, Percent_Identity=34.2105263157895, Blast_Score=163, Evalue=1e-40,
Organism=Drosophila melanogaster, GI24642146, Length=304, Percent_Identity=34.2105263157895, Blast_Score=163, Evalue=1e-40,
Organism=Drosophila melanogaster, GI24642144, Length=304, Percent_Identity=34.2105263157895, Blast_Score=163, Evalue=1e-40,
Organism=Drosophila melanogaster, GI24641720, Length=341, Percent_Identity=31.9648093841642, Blast_Score=135, Evalue=4e-32,
Organism=Drosophila melanogaster, GI281360801, Length=341, Percent_Identity=31.9648093841642, Blast_Score=135, Evalue=4e-32,
Organism=Drosophila melanogaster, GI281360799, Length=341, Percent_Identity=31.9648093841642, Blast_Score=135, Evalue=5e-32,
Organism=Drosophila melanogaster, GI24644244, Length=292, Percent_Identity=26.027397260274, Blast_Score=100, Evalue=9e-22,
Organism=Drosophila melanogaster, GI24657891, Length=306, Percent_Identity=25.4901960784314, Blast_Score=90, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000286 [H]

Pfam domain/function: PF00850 Hist_deacetyl [H]

EC number: NA

Molecular weight: Translated: 33817; Mature: 33817

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPVIYTDRFLEHRTGAMHPERPQRLAAIVERLRRSPLAPSLAWQEPRQATREQLLWVHS
CCCEEEHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHH
AELVETVEQVCRAGGGSLDPDTTVSAESFEVASLAAGGWLDGVDAVIRTGEPAWVLARPP
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHCCCCCEEEECCC
GHHAERGQAMGFCVFANAALAAHYALRVHGRTRVAVLDWDVHHGNGTQQLLWEESRLAYI
CCCCCCCCCCEEHHHHHHHHHHHHHEEECCCEEEEEEEEEEECCCCCHHHHHHCCCEEEE
SLHQSPHYPGTGHSHERGAADNVLNVPLPAGCARKEYQQALDTLVWPFIERFDPELLIVS
EEECCCCCCCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
AGFDGHIDDPLAEMALRASDYGDFARQALARTRRVLFGLEGGYDLDGLAESVFAVTEACL
CCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHH
SVRTRQV
HHHHCCC
>Mature Secondary Structure
MLPVIYTDRFLEHRTGAMHPERPQRLAAIVERLRRSPLAPSLAWQEPRQATREQLLWVHS
CCCEEEHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHH
AELVETVEQVCRAGGGSLDPDTTVSAESFEVASLAAGGWLDGVDAVIRTGEPAWVLARPP
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHCCCCCEEEECCC
GHHAERGQAMGFCVFANAALAAHYALRVHGRTRVAVLDWDVHHGNGTQQLLWEESRLAYI
CCCCCCCCCCEEHHHHHHHHHHHHHEEECCCEEEEEEEEEEECCCCCHHHHHHCCCEEEE
SLHQSPHYPGTGHSHERGAADNVLNVPLPAGCARKEYQQALDTLVWPFIERFDPELLIVS
EEECCCCCCCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
AGFDGHIDDPLAEMALRASDYGDFARQALARTRRVLFGLEGGYDLDGLAESVFAVTEACL
CCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHH
SVRTRQV
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]