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The map label for this gene is nlpI [C]

Identifier: 37520776

GI number: 37520776

Start: 1284145

End: 1285752

Strand: Direct

Name: nlpI [C]

Synonym: glr1207

Alternate gene names: 37520776

Gene position: 1284145-1285752 (Clockwise)

Preceding gene: 37520774

Following gene: 37520777

Centisome position: 27.56

GC content: 68.53

Gene sequence:

>1608_bases
ATGACTGCTTTGCGTCGCTTGCTCGGTTTATTGGTTGCCGTCTGGCTAGGTTGGGTTGCCCCACCCGCTCCGGGGGTGTC
GGCGGCACCGTCCAAGGCGACGATGCCGGTGGAGCGATGGCAGCAGGCCCAGACCCACCTGCGGCGGTCCGACTACGCGC
GTCTGGCCGACGAGTGCAGCCGGATGCTCCGGCAGGATGCCGCCTTTGAACCCGCCTACCGGTGGCGGGCACAGGCAAGA
TTGCGCCTGGGAGATCTAAAAGGGGGCCTGGCCGACGCCGAGCAGGCCATCCGGTTGGTGCCCACCAACGCCGAAGCGTA
TTTGCTGCGCGGCGAACTGCACGCCACCGCCGGTACCGCCGCGGCGGCCCGGGCTGATTATCTGCAGGCGGTGCAGGCCA
GCCCCGACGACGCCGAGGGGCTCAGGGTGCGGGCGATGGCCCAGTACGCTTTGGGCGACGGCGACGGAGCGTTGATGCAT
CTTGATCGCGCCGTTGTCCTCGACGCGCGCAAGGAGCGCGCCTACCTGCAACGGGGGTTGCTGCGCGCCCAGCGCGGCGA
TCGCGAGGGGGCGCGCGCCGACTATTTACGGGCGGTGGTCCTGGCCCACGACTATGTGCCCGCCCACCTGCAGCTGGCTG
CTCTGGCGCAGCAGCGCGGCGAGTACGCCGCCGCCGTCGAAACCCTGGACCGGGTCATCGAGCTGAACAAAAGCCACCCC
CTCGCCCACGCCAACCGGGGCCTGGCGAAGCTCAAGCTCAAAGAGTACCGGGCTGCCGCCGCCGATTTCAGCCGGGCCAT
TACCCTGAACGCCCCGGCACCGGCGATGCTCCGCCTCAACCGCGCCGTCGCCCTGGCCGAACTGAGGGACCATCCGGCGG
CTCTCACGGATCTGGGCGAAGCGATCCGCCTCGATCCGAAGCTCGCCGCCGCCCACGGCAACCGGGGTCTGGTGCGCACC
CGCTCGGGCGACTTTAAAGGAGCCATCGCCGATTTTGACCGGCAACTCGCCCTCGATCCGAGCAGTGCCGACGCCTACAT
CGGTCGGGCGGACGCCCGCACCCGCTCCGGGGATCTCCAGGGGGCGCTGGCTGATTTTGACCGGGCCGTCGATCTGTCGC
CTTCATCGTTTGCCCTACGCAGTCGGGCCGAGTTGCACGTGCGGCTCAAAGCTTACAAAGAAGCGATCGCCGACTACGAC
CGGGTGATCGCCCTGGAGCCGAAGCTTCCCACCGCTTATGTCGGCCGCGGCAACGCCCGCCTCGGCCTACAGGACACCCA
GGGGGCGCTTGCCGATTACGACCAGGCCCTCGCCCTGGATTCGGCCTTCGGACGGGCCTATTACAACCGCGGCCTCGCCA
ACTTCCGGCTGCGCAGTTACCGCAAGGCGGTCAACGACTTTGACCGGGCTCTGGACCACAACTTCGACAGCGCCCCGGTC
TTTCTCAATCGCGGTCTTGCCCTCGCGGGCCTGGGCGAGCGCGGTGCGGCGCTCGCCGACTGGCGCAAGGCTGCGACCCT
CTTTCGCGAGCGCAACGACCAGGTAGGTTACCGCCGTGCCCGCGAACTCATCGAGCGCGTCAGCCGCAAAAGCGACCTGT
TCGCCTGA

Upstream 100 bases:

>100_bases
CCCTGGATTTCTTGCCCATCCAGTGTAAGAGCCGTCGAACCACAACCGTTGCATCCCTACTGAACAACAGGTTTTTACCG
ACTGGCTCACCTTTTCGACT

Downstream 100 bases:

>100_bases
TCCAGTAAGCAACTGAAGAGCTTATCCGGCGTCGCGTCCGGCAATTGCCCTTTTGCCGGGATTGCTGCGGCCGGCATACG
ATGTGATGGTCTTACGCGCT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 535; Mature: 534

Protein sequence:

>535_residues
MTALRRLLGLLVAVWLGWVAPPAPGVSAAPSKATMPVERWQQAQTHLRRSDYARLADECSRMLRQDAAFEPAYRWRAQAR
LRLGDLKGGLADAEQAIRLVPTNAEAYLLRGELHATAGTAAAARADYLQAVQASPDDAEGLRVRAMAQYALGDGDGALMH
LDRAVVLDARKERAYLQRGLLRAQRGDREGARADYLRAVVLAHDYVPAHLQLAALAQQRGEYAAAVETLDRVIELNKSHP
LAHANRGLAKLKLKEYRAAAADFSRAITLNAPAPAMLRLNRAVALAELRDHPAALTDLGEAIRLDPKLAAAHGNRGLVRT
RSGDFKGAIADFDRQLALDPSSADAYIGRADARTRSGDLQGALADFDRAVDLSPSSFALRSRAELHVRLKAYKEAIADYD
RVIALEPKLPTAYVGRGNARLGLQDTQGALADYDQALALDSAFGRAYYNRGLANFRLRSYRKAVNDFDRALDHNFDSAPV
FLNRGLALAGLGERGAALADWRKAATLFRERNDQVGYRRARELIERVSRKSDLFA

Sequences:

>Translated_535_residues
MTALRRLLGLLVAVWLGWVAPPAPGVSAAPSKATMPVERWQQAQTHLRRSDYARLADECSRMLRQDAAFEPAYRWRAQAR
LRLGDLKGGLADAEQAIRLVPTNAEAYLLRGELHATAGTAAAARADYLQAVQASPDDAEGLRVRAMAQYALGDGDGALMH
LDRAVVLDARKERAYLQRGLLRAQRGDREGARADYLRAVVLAHDYVPAHLQLAALAQQRGEYAAAVETLDRVIELNKSHP
LAHANRGLAKLKLKEYRAAAADFSRAITLNAPAPAMLRLNRAVALAELRDHPAALTDLGEAIRLDPKLAAAHGNRGLVRT
RSGDFKGAIADFDRQLALDPSSADAYIGRADARTRSGDLQGALADFDRAVDLSPSSFALRSRAELHVRLKAYKEAIADYD
RVIALEPKLPTAYVGRGNARLGLQDTQGALADYDQALALDSAFGRAYYNRGLANFRLRSYRKAVNDFDRALDHNFDSAPV
FLNRGLALAGLGERGAALADWRKAATLFRERNDQVGYRRARELIERVSRKSDLFA
>Mature_534_residues
TALRRLLGLLVAVWLGWVAPPAPGVSAAPSKATMPVERWQQAQTHLRRSDYARLADECSRMLRQDAAFEPAYRWRAQARL
RLGDLKGGLADAEQAIRLVPTNAEAYLLRGELHATAGTAAAARADYLQAVQASPDDAEGLRVRAMAQYALGDGDGALMHL
DRAVVLDARKERAYLQRGLLRAQRGDREGARADYLRAVVLAHDYVPAHLQLAALAQQRGEYAAAVETLDRVIELNKSHPL
AHANRGLAKLKLKEYRAAAADFSRAITLNAPAPAMLRLNRAVALAELRDHPAALTDLGEAIRLDPKLAAAHGNRGLVRTR
SGDFKGAIADFDRQLALDPSSADAYIGRADARTRSGDLQGALADFDRAVDLSPSSFALRSRAELHVRLKAYKEAIADYDR
VIALEPKLPTAYVGRGNARLGLQDTQGALADYDQALALDSAFGRAYYNRGLANFRLRSYRKAVNDFDRALDHNFDSAPVF
LNRGLALAGLGERGAALADWRKAATLFRERNDQVGYRRARELIERVSRKSDLFA

Specific function: May Be Involved In Cell Division. Overexpression Of Nlpi Results In The Loss Of The Rod Morphology And The Formation Of Single Prolate Ellipsoids And Pairs Of Prolate Ellipsoids Joined By Partial Constrictions. [C]

COG id: COG0457

COG function: function code R; FOG: TPR repeat

Gene ontology:

Cell location: Attached To The Membrane By A Lipid Anchor [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 4 TPR repeats [H]

Homologues:

Organism=Homo sapiens, GI32307150, Length=380, Percent_Identity=29.7368421052632, Blast_Score=108, Evalue=2e-23,
Organism=Homo sapiens, GI32307148, Length=380, Percent_Identity=29.7368421052632, Blast_Score=108, Evalue=2e-23,
Organism=Homo sapiens, GI310123097, Length=355, Percent_Identity=25.0704225352113, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI310131789, Length=355, Percent_Identity=25.0704225352113, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI310110582, Length=355, Percent_Identity=25.0704225352113, Blast_Score=100, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI115532692, Length=377, Percent_Identity=26.525198938992, Blast_Score=99, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI115532690, Length=377, Percent_Identity=26.525198938992, Blast_Score=98, Evalue=9e-21,
Organism=Drosophila melanogaster, GI17647755, Length=360, Percent_Identity=28.3333333333333, Blast_Score=97, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24585827, Length=360, Percent_Identity=28.3333333333333, Blast_Score=97, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24585829, Length=360, Percent_Identity=28.3333333333333, Blast_Score=97, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001440
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF00515 TPR_1 [H]

EC number: NA

Molecular weight: Translated: 58620; Mature: 58489

Theoretical pI: Translated: 10.15; Mature: 10.15

Prosite motif: PS50005 TPR L=RR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTALRRLLGLLVAVWLGWVAPPAPGVSAAPSKATMPVERWQQAQTHLRRSDYARLADECS
CHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RMLRQDAAFEPAYRWRAQARLRLGDLKGGLADAEQAIRLVPTNAEAYLLRGELHATAGTA
HHHHHHCCCCHHHHHHHHHHHEECCCCCCHHCHHHCEEEECCCCCEEEEECCHHCCCCHH
AAARADYLQAVQASPDDAEGLRVRAMAQYALGDGDGALMHLDRAVVLDARKERAYLQRGL
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCEEEECHHHHHHHHHHHHHHHHHH
LRAQRGDREGARADYLRAVVLAHDYVPAHLQLAALAQQRGEYAAAVETLDRVIELNKSHP
HHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCC
LAHANRGLAKLKLKEYRAAAADFSRAITLNAPAPAMLRLNRAVALAELRDHPAALTDLGE
CHHHCCCHHHHHHHHHHHHHHHHHCEEEECCCCHHHHHHHHHHHHHHHHCCCHHHHHHHH
AIRLDPKLAAAHGNRGLVRTRSGDFKGAIADFDRQLALDPSSADAYIGRADARTRSGDLQ
HHCCCCHHEECCCCCCEEEECCCCCCCHHHHCCHHEECCCCCCCCCEECCCCCCCCCCCC
GALADFDRAVDLSPSSFALRSRAELHVRLKAYKEAIADYDRVIALEPKLPTAYVGRGNAR
HHHHHHHHHCCCCCCHHHHHCHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEECCCCCE
LGLQDTQGALADYDQALALDSAFGRAYYNRGLANFRLRSYRKAVNDFDRALDHNFDSAPV
ECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
FLNRGLALAGLGERGAALADWRKAATLFRERNDQVGYRRARELIERVSRKSDLFA
HHHCCEEEECCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TALRRLLGLLVAVWLGWVAPPAPGVSAAPSKATMPVERWQQAQTHLRRSDYARLADECS
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RMLRQDAAFEPAYRWRAQARLRLGDLKGGLADAEQAIRLVPTNAEAYLLRGELHATAGTA
HHHHHHCCCCHHHHHHHHHHHEECCCCCCHHCHHHCEEEECCCCCEEEEECCHHCCCCHH
AAARADYLQAVQASPDDAEGLRVRAMAQYALGDGDGALMHLDRAVVLDARKERAYLQRGL
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCEEEECHHHHHHHHHHHHHHHHHH
LRAQRGDREGARADYLRAVVLAHDYVPAHLQLAALAQQRGEYAAAVETLDRVIELNKSHP
HHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCC
LAHANRGLAKLKLKEYRAAAADFSRAITLNAPAPAMLRLNRAVALAELRDHPAALTDLGE
CHHHCCCHHHHHHHHHHHHHHHHHCEEEECCCCHHHHHHHHHHHHHHHHCCCHHHHHHHH
AIRLDPKLAAAHGNRGLVRTRSGDFKGAIADFDRQLALDPSSADAYIGRADARTRSGDLQ
HHCCCCHHEECCCCCCEEEECCCCCCCHHHHCCHHEECCCCCCCCCEECCCCCCCCCCCC
GALADFDRAVDLSPSSFALRSRAELHVRLKAYKEAIADYDRVIALEPKLPTAYVGRGNAR
HHHHHHHHHCCCCCCHHHHHCHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEECCCCCE
LGLQDTQGALADYDQALALDSAFGRAYYNRGLANFRLRSYRKAVNDFDRALDHNFDSAPV
ECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
FLNRGLALAGLGERGAALADWRKAATLFRERNDQVGYRRARELIERVSRKSDLFA
HHHCCEEEECCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1368342; 8905231 [H]