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The map label for this gene is cmpR [H]

Identifier: 37520570

GI number: 37520570

Start: 1072648

End: 1073592

Strand: Reverse

Name: cmpR [H]

Synonym: gll1001

Alternate gene names: 37520570

Gene position: 1073592-1072648 (Counterclockwise)

Preceding gene: 37520571

Following gene: 37520565

Centisome position: 23.04

GC content: 61.9

Gene sequence:

>945_bases
TTGAAGCACGCCACATTGCACCAGCTGCAGGTGTTTCAGGTGGTTGCGCGCCACCGCAGCTTCACGCGCGCCGCGGAGGA
GTTGTTCCTCACCCAGCCGACCGTCTCGATGCAGATCAAGCAGCTGACCCGGGCGGTTGGGATGCCGCTGTTCGAGCAGA
TCGGCAAGCGGTTGTTTTTGACGGATGCGGGCCGGGAGCTGCTCGCCACCTGCGAAGAGATATTCACCCGTCTGGCCCAG
TTCGAGATGACCGTCTCCGACATGCAGGGGCTCAAAAAAGGGCAATTGCGCCTCGCGGTGGTGACAACAGCCAAGTACTT
TGCGCCGCGCCTTTTGGGGCCGTTTTGCCAGCGCTATCCGGAGATCGACATTTCGCTGGAGGTGGCCAACCGCGGCCGGG
TGCTCGAACGGTTGGCGGAGAACCTCGATGATTTTTATATCGTCGGCCAGGTGCCCGAGGATCTCAACGTCGAGATGCAT
CCGTTTCTCGATGACCAACTGGTGGTGATTGCGCCCTACCACCATCCGCTGGCGCTGCAGCGCAATATTCCTGCGAGCCG
TCTGGTGCAAGAACCCTTTTTGATGCGCGAACCCGGCTCGGGCACGCGCATGGTGGTGCAGCAATTTTTCGAAGAGCGCC
GTCTCACCCCGCGCGTCAAGATGGAACTGGGCAGTTCCGAAGCGATTAAGCAGGCGGTCATCGGCGGATTGGGCATCGCA
GTGCTCTCCCACCACGCCCTGGCGAGCGAAGGGGCGTTGCACCATCTGGCCATCCTCAATGTCGAAGGTTTTCCGATCCG
CCGCCACTGGCATGTCGTCTATCCGGCGGGCAAGCGCCTCTCGGTGGTCGCCCGCACGTTCTTGCAGTACCTCATCGAAG
AGGGCCGCGAGGTGGCCGAGCGCACCAGCTTCGAGATGACCAGTCTGTTGGAGCGGCCCGCCTGA

Upstream 100 bases:

>100_bases
GTCGGCTGGTAGATGAGAACATTCTCATTCAGCCATCACCTTAAGTTGATGTTATTCCTGTTCATGATAGAACTATGTCT
ATAGGTGCTGGAGGATCGTC

Downstream 100 bases:

>100_bases
ATTCGCCTCAACGGCGCAGGTGCTGCCAGCATTCCCGGGCAATCGCCCAGTCCTCCTGGGTGTGAATGACCAGCACCCGC
ACCGCTGAATCCGCGGCGGC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 314; Mature: 314

Protein sequence:

>314_residues
MKHATLHQLQVFQVVARHRSFTRAAEELFLTQPTVSMQIKQLTRAVGMPLFEQIGKRLFLTDAGRELLATCEEIFTRLAQ
FEMTVSDMQGLKKGQLRLAVVTTAKYFAPRLLGPFCQRYPEIDISLEVANRGRVLERLAENLDDFYIVGQVPEDLNVEMH
PFLDDQLVVIAPYHHPLALQRNIPASRLVQEPFLMREPGSGTRMVVQQFFEERRLTPRVKMELGSSEAIKQAVIGGLGIA
VLSHHALASEGALHHLAILNVEGFPIRRHWHVVYPAGKRLSVVARTFLQYLIEEGREVAERTSFEMTSLLERPA

Sequences:

>Translated_314_residues
MKHATLHQLQVFQVVARHRSFTRAAEELFLTQPTVSMQIKQLTRAVGMPLFEQIGKRLFLTDAGRELLATCEEIFTRLAQ
FEMTVSDMQGLKKGQLRLAVVTTAKYFAPRLLGPFCQRYPEIDISLEVANRGRVLERLAENLDDFYIVGQVPEDLNVEMH
PFLDDQLVVIAPYHHPLALQRNIPASRLVQEPFLMREPGSGTRMVVQQFFEERRLTPRVKMELGSSEAIKQAVIGGLGIA
VLSHHALASEGALHHLAILNVEGFPIRRHWHVVYPAGKRLSVVARTFLQYLIEEGREVAERTSFEMTSLLERPA
>Mature_314_residues
MKHATLHQLQVFQVVARHRSFTRAAEELFLTQPTVSMQIKQLTRAVGMPLFEQIGKRLFLTDAGRELLATCEEIFTRLAQ
FEMTVSDMQGLKKGQLRLAVVTTAKYFAPRLLGPFCQRYPEIDISLEVANRGRVLERLAENLDDFYIVGQVPEDLNVEMH
PFLDDQLVVIAPYHHPLALQRNIPASRLVQEPFLMREPGSGTRMVVQQFFEERRLTPRVKMELGSSEAIKQAVIGGLGIA
VLSHHALASEGALHHLAILNVEGFPIRRHWHVVYPAGKRLSVVARTFLQYLIEEGREVAERTSFEMTSLLERPA

Specific function: Activates transcription of the cmpABCD operon under carbon dioxide-limited conditions [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI157672245, Length=223, Percent_Identity=31.8385650224215, Blast_Score=117, Evalue=9e-28,
Organism=Escherichia coli, GI1788481, Length=294, Percent_Identity=31.2925170068027, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI145693105, Length=310, Percent_Identity=27.0967741935484, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1787530, Length=248, Percent_Identity=27.0161290322581, Blast_Score=95, Evalue=6e-21,
Organism=Escherichia coli, GI1787879, Length=241, Percent_Identity=26.9709543568465, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1789204, Length=244, Percent_Identity=24.5901639344262, Blast_Score=88, Evalue=9e-19,
Organism=Escherichia coli, GI87082132, Length=289, Percent_Identity=27.681660899654, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1789173, Length=151, Percent_Identity=37.7483443708609, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1790399, Length=277, Percent_Identity=24.9097472924188, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1788748, Length=244, Percent_Identity=25.4098360655738, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1786401, Length=295, Percent_Identity=25.7627118644068, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1790208, Length=242, Percent_Identity=28.099173553719, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788887, Length=244, Percent_Identity=25.4098360655738, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1787806, Length=270, Percent_Identity=25.9259259259259, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788296, Length=243, Percent_Identity=23.8683127572016, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1787589, Length=300, Percent_Identity=26.6666666666667, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788297, Length=242, Percent_Identity=26.0330578512397, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1787601, Length=217, Percent_Identity=23.5023041474654, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35669; Mature: 35669

Theoretical pI: Translated: 8.28; Mature: 8.28

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHATLHQLQVFQVVARHRSFTRAAEELFLTQPTVSMQIKQLTRAVGMPLFEQIGKRLFL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHCCEEEE
TDAGRELLATCEEIFTRLAQFEMTVSDMQGLKKGQLRLAVVTTAKYFAPRLLGPFCQRYP
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHCC
EIDISLEVANRGRVLERLAENLDDFYIVGQVPEDLNVEMHPFLDDQLVVIAPYHHPLALQ
CCEEEEEECCCCHHHHHHHHCCCCEEEEECCCCCCCCEECCCCCCCEEEEECCCCCEEEE
RNIPASRLVQEPFLMREPGSGTRMVVQQFFEERRLTPRVKMELGSSEAIKQAVIGGLGIA
CCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHH
VLSHHALASEGALHHLAILNVEGFPIRRHWHVVYPAGKRLSVVARTFLQYLIEEGREVAE
HHHHHHHHCCCCEEEEEEEECCCCEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHH
RTSFEMTSLLERPA
HHHHHHHHHHHCCC
>Mature Secondary Structure
MKHATLHQLQVFQVVARHRSFTRAAEELFLTQPTVSMQIKQLTRAVGMPLFEQIGKRLFL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHCCEEEE
TDAGRELLATCEEIFTRLAQFEMTVSDMQGLKKGQLRLAVVTTAKYFAPRLLGPFCQRYP
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHCC
EIDISLEVANRGRVLERLAENLDDFYIVGQVPEDLNVEMHPFLDDQLVVIAPYHHPLALQ
CCEEEEEECCCCHHHHHHHHCCCCEEEEECCCCCCCCEECCCCCCCEEEEECCCCCEEEE
RNIPASRLVQEPFLMREPGSGTRMVVQQFFEERRLTPRVKMELGSSEAIKQAVIGGLGIA
CCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHH
VLSHHALASEGALHHLAILNVEGFPIRRHWHVVYPAGKRLSVVARTFLQYLIEEGREVAE
HHHHHHHHCCCCEEEEEEEECCCCEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHH
RTSFEMTSLLERPA
HHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA