| Definition | Gloeobacter violaceus PCC 7421 chromosome, complete genome. |
|---|---|
| Accession | NC_005125 |
| Length | 4,659,019 |
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The map label for this gene is ppiA [C]
Identifier: 37520542
GI number: 37520542
Start: 1033590
End: 1034321
Strand: Direct
Name: ppiA [C]
Synonym: glr0973
Alternate gene names: 37520542
Gene position: 1033590-1034321 (Clockwise)
Preceding gene: 37520541
Following gene: 37520544
Centisome position: 22.18
GC content: 65.98
Gene sequence:
>732_bases ATGCAACGGATACGACGGTTGGCCGGCGTGCTTGCGGGCGTCGCCTTCGTCCTGGCTACGACCGCCTGCACCCAGGCCGG AGCACCACCGGCCGCCCCACAGGAGAATCCCACGGTGAACAATCCCAGCGGCGCCCGGGCCGATTTGCCCTCCCTCGCGG GCAAGGCCACCGTCGATCTGAACACCTCCAAAGGCCGCATCCTCCTCGAGGTCGACGGCGATAACGCTCCGCTCTCCGCC GGCAACTTCGTCGACCTAGTCAAGCGCGGGTTCTACAACAACCTTGCGTTTCACCGGGTGGTGTCGGGGTTTGTCATCCA GGGCGGCGATCCGCTCGGCAATGGTACCGGCGGCTTTATCGACCCGGCCACGCGCCAGCCGCGTTCGCTGCCTTTGGAGA TTCGCGCCACTACTGGCGACGGCCGGCCGGGCGAGATTCTTTATGGCCAGACATTTAGCCTCAGCGGGCGCAACCCCCGC ACCCAGCCGCCGGTACTCGTCCATAGCCGGGGGGCTCTGGCCATGGCCCGGTCGCAAAATCCCAACTCGGCCTCGTCGCA GTTTTATATCACCCTAGCGGAAACCCGGCAGCTCGACGGCGAATACGCCGTCTTCGGCAAGGTGCTCGAAGGCCAGGATG TGGTCGATAAAATTCAGGTGGGCGACAAGATTCTCTCGGCCACCGTCGTCTCCGGGGGCGGCGACCCGGTCGGCGGCTCG GCCCCCGGTTAG
Upstream 100 bases:
>100_bases GCGCCGACGCTTCGAGCAAGAAGTAGGCGGAGCGGTCCCCGGCGCCTGACACTCACGGTACAATCTCTGGGCGGCAAAAA CGTTCGAGGAATCTGCTTCC
Downstream 100 bases:
>100_bases CGCGAGGCCGTCTGCAAGCGGCGCTGCGCTTCGCGCAGGCTGATCTGGGCGAGGGAGCGGTAGAAGACCACCAGTTCCTC CGACGGGTTGGCGTTCGCCA
Product: peptidyl-prolyl cis-trans isomerase
Products: NA
Alternate protein names: PPIase sll0227; Rotamase sll0227 [H]
Number of amino acids: Translated: 243; Mature: 243
Protein sequence:
>243_residues MQRIRRLAGVLAGVAFVLATTACTQAGAPPAAPQENPTVNNPSGARADLPSLAGKATVDLNTSKGRILLEVDGDNAPLSA GNFVDLVKRGFYNNLAFHRVVSGFVIQGGDPLGNGTGGFIDPATRQPRSLPLEIRATTGDGRPGEILYGQTFSLSGRNPR TQPPVLVHSRGALAMARSQNPNSASSQFYITLAETRQLDGEYAVFGKVLEGQDVVDKIQVGDKILSATVVSGGGDPVGGS APG
Sequences:
>Translated_243_residues MQRIRRLAGVLAGVAFVLATTACTQAGAPPAAPQENPTVNNPSGARADLPSLAGKATVDLNTSKGRILLEVDGDNAPLSA GNFVDLVKRGFYNNLAFHRVVSGFVIQGGDPLGNGTGGFIDPATRQPRSLPLEIRATTGDGRPGEILYGQTFSLSGRNPR TQPPVLVHSRGALAMARSQNPNSASSQFYITLAETRQLDGEYAVFGKVLEGQDVVDKIQVGDKILSATVVSGGGDPVGGS APG >Mature_243_residues MQRIRRLAGVLAGVAFVLATTACTQAGAPPAAPQENPTVNNPSGARADLPSLAGKATVDLNTSKGRILLEVDGDNAPLSA GNFVDLVKRGFYNNLAFHRVVSGFVIQGGDPLGNGTGGFIDPATRQPRSLPLEIRATTGDGRPGEILYGQTFSLSGRNPR TQPPVLVHSRGALAMARSQNPNSASSQFYITLAETRQLDGEYAVFGKVLEGQDVVDKIQVGDKILSATVVSGGGDPVGGS APG
Specific function: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides [H]
COG id: COG0652
COG function: function code O; Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family
Gene ontology:
Cell location: Periplasmic Protein [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 PPIase cyclophilin-type domain [H]
Homologues:
Organism=Homo sapiens, GI7706339, Length=161, Percent_Identity=35.4037267080745, Blast_Score=100, Evalue=2e-21, Organism=Homo sapiens, GI19557636, Length=164, Percent_Identity=31.7073170731707, Blast_Score=84, Evalue=1e-16, Organism=Homo sapiens, GI4758950, Length=176, Percent_Identity=32.9545454545455, Blast_Score=82, Evalue=5e-16, Organism=Homo sapiens, GI4505991, Length=184, Percent_Identity=32.6086956521739, Blast_Score=82, Evalue=5e-16, Organism=Homo sapiens, GI64276486, Length=149, Percent_Identity=31.5436241610738, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI10863927, Length=159, Percent_Identity=32.7044025157233, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI5031987, Length=159, Percent_Identity=35.8490566037736, Blast_Score=76, Evalue=3e-14, Organism=Homo sapiens, GI22547215, Length=169, Percent_Identity=33.7278106508876, Blast_Score=74, Evalue=2e-13, Organism=Homo sapiens, GI303305009, Length=165, Percent_Identity=33.3333333333333, Blast_Score=73, Evalue=2e-13, Organism=Homo sapiens, GI310110104, Length=159, Percent_Identity=32.0754716981132, Blast_Score=73, Evalue=2e-13, Organism=Homo sapiens, GI22547212, Length=169, Percent_Identity=33.7278106508876, Blast_Score=73, Evalue=2e-13, Organism=Homo sapiens, GI7657473, Length=169, Percent_Identity=33.7278106508876, Blast_Score=73, Evalue=2e-13, Organism=Homo sapiens, GI310129267, Length=159, Percent_Identity=31.4465408805031, Blast_Score=73, Evalue=2e-13, Organism=Homo sapiens, GI310120620, Length=159, Percent_Identity=31.4465408805031, Blast_Score=73, Evalue=2e-13, Organism=Homo sapiens, GI24308049, Length=160, Percent_Identity=31.25, Blast_Score=72, Evalue=3e-13, Organism=Homo sapiens, GI5174637, Length=164, Percent_Identity=32.9268292682927, Blast_Score=72, Evalue=6e-13, Organism=Homo sapiens, GI45439316, Length=164, Percent_Identity=32.9268292682927, Blast_Score=72, Evalue=6e-13, Organism=Homo sapiens, GI150418007, Length=158, Percent_Identity=33.5443037974684, Blast_Score=69, Evalue=5e-12, Organism=Homo sapiens, GI20911035, Length=162, Percent_Identity=29.6296296296296, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI42560244, Length=170, Percent_Identity=28.8235294117647, Blast_Score=66, Evalue=2e-11, Organism=Escherichia coli, GI1789763, Length=170, Percent_Identity=40, Blast_Score=106, Evalue=1e-24, Organism=Escherichia coli, GI1786736, Length=171, Percent_Identity=35.672514619883, Blast_Score=97, Evalue=1e-21, Organism=Caenorhabditis elegans, GI17539496, Length=160, Percent_Identity=36.875, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI17506311, Length=160, Percent_Identity=33.125, Blast_Score=85, Evalue=4e-17, Organism=Caenorhabditis elegans, GI71980594, Length=164, Percent_Identity=32.3170731707317, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI71980590, Length=164, Percent_Identity=32.3170731707317, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17552780, Length=201, Percent_Identity=31.3432835820896, Blast_Score=82, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17552784, Length=194, Percent_Identity=32.4742268041237, Blast_Score=82, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17506307, Length=187, Percent_Identity=32.0855614973262, Blast_Score=81, Evalue=4e-16, Organism=Caenorhabditis elegans, GI17532641, Length=168, Percent_Identity=30.952380952381, Blast_Score=78, Evalue=5e-15, Organism=Caenorhabditis elegans, GI17559074, Length=179, Percent_Identity=31.2849162011173, Blast_Score=76, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17566266, Length=179, Percent_Identity=31.2849162011173, Blast_Score=75, Evalue=3e-14, Organism=Caenorhabditis elegans, GI17539498, Length=158, Percent_Identity=32.2784810126582, Blast_Score=74, Evalue=8e-14, Organism=Caenorhabditis elegans, GI17552782, Length=165, Percent_Identity=30.3030303030303, Blast_Score=71, Evalue=4e-13, Organism=Caenorhabditis elegans, GI17551284, Length=165, Percent_Identity=30.9090909090909, Blast_Score=71, Evalue=4e-13, Organism=Caenorhabditis elegans, GI17551282, Length=165, Percent_Identity=30.9090909090909, Blast_Score=71, Evalue=4e-13, Organism=Caenorhabditis elegans, GI71997782, Length=161, Percent_Identity=29.8136645962733, Blast_Score=71, Evalue=6e-13, Organism=Caenorhabditis elegans, GI32563659, Length=161, Percent_Identity=27.3291925465839, Blast_Score=68, Evalue=5e-12, Organism=Caenorhabditis elegans, GI17565860, Length=166, Percent_Identity=31.3253012048193, Blast_Score=66, Evalue=2e-11, Organism=Saccharomyces cerevisiae, GI6320510, Length=181, Percent_Identity=30.939226519337, Blast_Score=71, Evalue=2e-13, Organism=Saccharomyces cerevisiae, GI6320359, Length=158, Percent_Identity=31.6455696202532, Blast_Score=70, Evalue=4e-13, Organism=Saccharomyces cerevisiae, GI6321848, Length=182, Percent_Identity=31.8681318681319, Blast_Score=69, Evalue=8e-13, Organism=Saccharomyces cerevisiae, GI6323562, Length=162, Percent_Identity=30.8641975308642, Blast_Score=67, Evalue=3e-12, Organism=Drosophila melanogaster, GI17986117, Length=164, Percent_Identity=38.4146341463415, Blast_Score=100, Evalue=1e-21, Organism=Drosophila melanogaster, GI19922376, Length=169, Percent_Identity=33.7278106508876, Blast_Score=100, Evalue=1e-21, Organism=Drosophila melanogaster, GI21357249, Length=176, Percent_Identity=31.8181818181818, Blast_Score=77, Evalue=1e-14, Organism=Drosophila melanogaster, GI24652460, Length=163, Percent_Identity=28.2208588957055, Blast_Score=76, Evalue=2e-14, Organism=Drosophila melanogaster, GI45549139, Length=215, Percent_Identity=29.3023255813954, Blast_Score=76, Evalue=2e-14, Organism=Drosophila melanogaster, GI24664125, Length=160, Percent_Identity=34.375, Blast_Score=71, Evalue=8e-13, Organism=Drosophila melanogaster, GI21357783, Length=160, Percent_Identity=34.375, Blast_Score=71, Evalue=8e-13, Organism=Drosophila melanogaster, GI17136360, Length=178, Percent_Identity=30.8988764044944, Blast_Score=68, Evalue=5e-12, Organism=Drosophila melanogaster, GI20130249, Length=158, Percent_Identity=31.0126582278481, Blast_Score=67, Evalue=9e-12,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR015891 - InterPro: IPR020892 - InterPro: IPR002130 [H]
Pfam domain/function: PF00160 Pro_isomerase [H]
EC number: =5.2.1.8 [H]
Molecular weight: Translated: 25132; Mature: 25132
Theoretical pI: Translated: 9.07; Mature: 9.07
Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00170 CSA_PPIASE_1 ; PS50072 CSA_PPIASE_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 0.8 %Met (Translated Protein) 1.2 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 0.8 %Met (Mature Protein) 1.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MQRIRRLAGVLAGVAFVLATTACTQAGAPPAAPQENPTVNNPSGARADLPSLAGKATVDL CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCEEEEE NTSKGRILLEVDGDNAPLSAGNFVDLVKRGFYNNLAFHRVVSGFVIQGGDPLGNGTGGFI ECCCCEEEEEECCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHCEEEECCCCCCCCCCCCC DPATRQPRSLPLEIRATTGDGRPGEILYGQTFSLSGRNPRTQPPVLVHSRGALAMARSQN CCCCCCCCCCCEEEEEECCCCCCCEEEECCEEEECCCCCCCCCCEEEECCCCEEEECCCC PNSASSQFYITLAETRQLDGEYAVFGKVLEGQDVVDKIQVGDKILSATVVSGGGDPVGGS CCCCCCEEEEEEECCCCCCCCEEEEEEECCCHHHHHHHHHCCCEEEEEEECCCCCCCCCC APG CCC >Mature Secondary Structure MQRIRRLAGVLAGVAFVLATTACTQAGAPPAAPQENPTVNNPSGARADLPSLAGKATVDL CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCEEEEE NTSKGRILLEVDGDNAPLSAGNFVDLVKRGFYNNLAFHRVVSGFVIQGGDPLGNGTGGFI ECCCCEEEEEECCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHCEEEECCCCCCCCCCCCC DPATRQPRSLPLEIRATTGDGRPGEILYGQTFSLSGRNPRTQPPVLVHSRGALAMARSQN CCCCCCCCCCCEEEEEECCCCCCCEEEECCEEEECCCCCCCCCCEEEECCCCEEEECCCC PNSASSQFYITLAETRQLDGEYAVFGKVLEGQDVVDKIQVGDKILSATVVSGGGDPVGGS CCCCCCEEEEEEECCCCCCCCEEEEEEECCCHHHHHHHHHCCCEEEEEEECCCCCCCCCC APG CCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 8905231 [H]