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The map label for this gene is accC2 [H]

Identifier: 37520527

GI number: 37520527

Start: 1015311

End: 1018919

Strand: Reverse

Name: accC2 [H]

Synonym: gll0958

Alternate gene names: 37520527

Gene position: 1018919-1015311 (Counterclockwise)

Preceding gene: 37520528

Following gene: 37520526

Centisome position: 21.87

GC content: 65.78

Gene sequence:

>3609_bases
ATGTTCGACAAAGTCTTGATTGCCAACCGGGGCGAAATCGCCTGCCGCATCCTGCGCACCCTCGACCGGCTGGGGATCGC
CTCGGTGGCGGTGTACTCCGAGGCGGACGCCTACGCCCCCCACGTCCGGGGAGCGGGTGAAGCGGTCCTGATTGGCCCCG
CCCCGGCGGCCCAGAGCTATTTGCGCTACGAGCGGATTTTAGAAGCGGCCGTCGCCACCGGTGCCCAGGCGATCCACCCG
GGCTACGGTTTTTTGAGCGAGAACGCCGAATTTGCCGAGGCGTGCGAACGCGAGAATATTGTCTTTATTGGACCTACCCC
CTTGCAGATGGGTCGCTTCGGGCGCAAGCACACCGCCCGCGCTCTGGCGGCCGAAAACGGTGTGCCCCTGTTGCCGGGGA
CGGGCTTGCTCATCGATCTTGCCGAAGCGCACCGGCAGGCGGCGGCGATTGGCTACCCGGTGATGCTCAAGAGCACGGCG
GGTGGGGGCGGGATCGGCCTGGCACTCTGTCGGGGAGAAGCGAAACTCACCGAATCGTTCCAGGCCGTGCAGCGGCTCAG
CGAAAACAATTTCCGCGACGGCGGCGTGTACCTCGAAAAATACGTCGAGCGCGCCCGGCACCTGGAGGTGCAGATCTTCG
GCGACGGCGAGGGTAGGGTGATCGCCCTGGGCGAGCGCGACTGCTCGATCCAGCGGCGCAACCAGAAGCTGCTTGAGGAG
ACCCCGGCCCCCGGTATTTGCGAGACGCTGCGCGAACGGCTTTGTGAAGCGGCGGTGTGCCTGGGGCGGGCGGTCGGCTA
TCGCTCGGCGGGGACGGTGGAATTTATCTACGACGCCGAGGCGGCGGATTTTTATTTTCTGGAGGTGAACACCCGTCTGC
AGGTGGAGCACGGCGTCACCGAGGCGGTGGCGGGGATCGACCTGGTCGAATGGATGGTGCGCCTGGCGGCCGGGGAGCGC
GACTTTCTCGAGCAGTACCGCCACCGGCCCCGGGGGCATGCCGTCGAGGTGCGGCTCTACGCCGAGGATGCGGGCCGCAA
TTTTCAGCCCAGCACCGGCACGCTCACCGAAGCGGTCTTTGCGGCGGTGCGCTGCGACGGCTGGGTGGAGCGGGGCACGG
AGGTGACGCCCTACTACGACCCCTTGCTCGCCAAGCTCATCGTCCGGGGTGAATCGCGACCCGAGGCGATCGCCCGTCTG
CAGGCCGCGCTTGCGGACACCCGCATCGCCGGGGTGGAGACCAACCTGGACTACCTGCGCCAGATCCTTGCGGACGCCGA
TTTTTTGGCGGGCAACCTGAGTACCCGCTTCTCGCAAACTTTTCACTACGCGCCGCTGACCGTCGAGGTGCTGGAGCCCG
GTACCTACAGCACCATCCAGGACTACCCGGGGCGCACCGGCTACTGGGATATCGGCGTGCCGCCCTCCGGCCCGATGGAC
CCGCTCGCCTTCCGCCTTGCCAACCGCCTGGTGGGCAACCCCCCCGAGACGGCCGGGCTCGAATGCACTGCCCTCGGCCC
GACCTTGCGTTTCCACACCGACGCGGTGATCTGCCTGTGCGGTGCCGCGATGGACGCCCGGATCGACAGCAAACCCGTTT
CCTACTGGTGCGCCGTGCCGGTGGCGGCAGGCAGCACCCTGCGCCTGGGGGCCGTCACCGGCCCCGGCTACCGCACCTAC
CTGGCGGTCCGGGGTGGTTTCGACGTGCCCGAGTATCTGGACAGCAAGGCGACTTTTACCCTGGGACAATTCGGCGGCCA
CTGCGGTCGGACGCTGCGCACCGGCGATGTGCTCCGGCTGGTGCGGCATGATCTTGCAGACCTCCCGCTGCCGCTCGCTC
CCGCTCTCATCCCCGAATACCGCTCCGATTGGGAAATTGGTGTACTCTACGGTCCCCACGGAGCGCCGGACTTTTTTACC
GACCGGGACATCGAGACATTTTTTGCCACCGCTTGGGAAGTTCACTACAACTCAGCGCGCACCGGCGTGCGGCTCATCGG
TCCCAAACCGCTATGGGCGCGCTCCGACGGCGGCGAAGCGGGATTGCACCCGTCGAATATTCATGACAATGCCTATGCGG
TGGGCACGGTCGATTTCACCGGCGACATGCCAGTCATCCTCGGTCCCGACGGCCCGAGCCTGGGAGGCTTCGTCTGCCCG
GCTACTGTCGCCCGGGCGGAACTGTGGAAAATCGGCCAACTCAAACCGGGAGACACCGTCCGCTTCCGGCGGCTGGGTTT
TGCCGAAGCCCTGCGCCGCGAACAAGCACAAGATTTCACAATCGATCGACTCTCCCTTCCGAAACCGGCTGCGCCCTCGC
TTGCCGAAGCCGGCGACCCGGCGGTGCTGCACACCATCGCGGCCACTGCGGAGCAAATCGCCGTCGTCTACCGCCAGTCG
GGGGACAAGTACCTGCTTATCGAGTACGGCCCGCCGGTGCTCGATCTCAATTTGCGCTTCCGGGTGCACGCGCTGATGGA
GTGGCTGCAGGCCAACGCCTTGCCGGGCATGCTCGAACTCACCCCCGGCATCCGCTCGCTGCAGGTGCACTTCGACGGCC
GCATCCTGCCGCGCGAAAGGTTGCTGGAGGTTCTGACCGCCGCAGAGTCGCAACTGCCCCCGATCGAGGCGATGGAGGTG
CCCACCCGTATCCTGCACCTGCCTTTGTCCTGGGAAGACGAATCGACGCTGCTCGCCATCCGCAAGTACATGCAGTCGGT
GCGCAAGGACGCTCCCTGGTGTCCGAGCAACATCGAATTTATCCGCCGCATCAACGGGCTTGAAAGTATTGACGAGGTGA
AGCGCATCGTCTTCGAGGCGAGCTACCTGGTATTGGGCCTGGGCGATGTCTACCTTGGAGCGCCCGTCGCTACCCCAATC
GATCCGCGCCACCGGCTGGTCACCACCAAGTACAACCCGGCGCGCACCTGGACACCCGAAAACGCCGTGGGCATCGGCGG
CGCGTATCTCTGCATCTACGGCATGGAGGGACCGGGGGGCTACCAGTTCGTGGGCCGTACCGTCCAGGTCTGGAACCGCT
ACCGGCAGACCGCCGATTTTACCCGGCCCTGGCTGCTGCGCTTTTTTGATCAGATCCGCTTCTATCCGGTTTCCGGGCCG
GAACTGTTGCGCCTGCGCGAGGATTTTCGCCACGGCCGCGCGAAGCTCGAGGTGAGCGAAGCGATCTTCAGCCTGAAACA
ATACAACGACTTTTTAGCCGAGATCGCCCCGGAGGCCGCAGCCTTTAAAGCGCAGCAGCAGACGGCCTTTGCCGAGGAGC
GCGAGCGGTGGCGCGAGGCGGGCGAATTTGCCGCCGTCGCCGAAGATCCGGCTATTGCGCCGTCTGCGGCCGAGGAGTAC
GCACTGCCCGCCGGAGCCTGCGCGGTGAGCGCCCAGCTCTCGGCGAATGTCTGGCAGATTGCCGTCCAACCGGGAGAGCC
GGTCGCCGCCGGTGATCCCCTGGTGATCTTGGAGTCGATGAAGATGGAGGTTGTCCTGACCGCTCCCATCTCCGGTACAG
TCCTCGCGGTGCTGTGCGCCGAAGGGTGTCTGGTCGCCGCCGGCCAGACGCTTGTGGTCGTGCAACCTTCCGAGTCCGCG
CCGCCATAG

Upstream 100 bases:

>100_bases
CTGCAACGGCTACAATCCGACCCCCATCCGGCTGGTCATCTGGGCTCCGCCCCCGCCTGACCCCTGCCGCTAAACTTACC
TACCCGACGACGACGTTCGC

Downstream 100 bases:

>100_bases
CACCCGGACATCCAAAATTTGTATTTTCTATACTCCACTTCTACAGAGGAAAAACCGATGACCGCCATCCAACCGCCCCG
CCCAAGGACTTACGAACTGC

Product: urea amidolyase

Products: NA

Alternate protein names: Acetyl-CoA carboxylase subunit A 2; ACC 2 [H]

Number of amino acids: Translated: 1202; Mature: 1202

Protein sequence:

>1202_residues
MFDKVLIANRGEIACRILRTLDRLGIASVAVYSEADAYAPHVRGAGEAVLIGPAPAAQSYLRYERILEAAVATGAQAIHP
GYGFLSENAEFAEACERENIVFIGPTPLQMGRFGRKHTARALAAENGVPLLPGTGLLIDLAEAHRQAAAIGYPVMLKSTA
GGGGIGLALCRGEAKLTESFQAVQRLSENNFRDGGVYLEKYVERARHLEVQIFGDGEGRVIALGERDCSIQRRNQKLLEE
TPAPGICETLRERLCEAAVCLGRAVGYRSAGTVEFIYDAEAADFYFLEVNTRLQVEHGVTEAVAGIDLVEWMVRLAAGER
DFLEQYRHRPRGHAVEVRLYAEDAGRNFQPSTGTLTEAVFAAVRCDGWVERGTEVTPYYDPLLAKLIVRGESRPEAIARL
QAALADTRIAGVETNLDYLRQILADADFLAGNLSTRFSQTFHYAPLTVEVLEPGTYSTIQDYPGRTGYWDIGVPPSGPMD
PLAFRLANRLVGNPPETAGLECTALGPTLRFHTDAVICLCGAAMDARIDSKPVSYWCAVPVAAGSTLRLGAVTGPGYRTY
LAVRGGFDVPEYLDSKATFTLGQFGGHCGRTLRTGDVLRLVRHDLADLPLPLAPALIPEYRSDWEIGVLYGPHGAPDFFT
DRDIETFFATAWEVHYNSARTGVRLIGPKPLWARSDGGEAGLHPSNIHDNAYAVGTVDFTGDMPVILGPDGPSLGGFVCP
ATVARAELWKIGQLKPGDTVRFRRLGFAEALRREQAQDFTIDRLSLPKPAAPSLAEAGDPAVLHTIAATAEQIAVVYRQS
GDKYLLIEYGPPVLDLNLRFRVHALMEWLQANALPGMLELTPGIRSLQVHFDGRILPRERLLEVLTAAESQLPPIEAMEV
PTRILHLPLSWEDESTLLAIRKYMQSVRKDAPWCPSNIEFIRRINGLESIDEVKRIVFEASYLVLGLGDVYLGAPVATPI
DPRHRLVTTKYNPARTWTPENAVGIGGAYLCIYGMEGPGGYQFVGRTVQVWNRYRQTADFTRPWLLRFFDQIRFYPVSGP
ELLRLREDFRHGRAKLEVSEAIFSLKQYNDFLAEIAPEAAAFKAQQQTAFAEERERWREAGEFAAVAEDPAIAPSAAEEY
ALPAGACAVSAQLSANVWQIAVQPGEPVAAGDPLVILESMKMEVVLTAPISGTVLAVLCAEGCLVAAGQTLVVVQPSESA
PP

Sequences:

>Translated_1202_residues
MFDKVLIANRGEIACRILRTLDRLGIASVAVYSEADAYAPHVRGAGEAVLIGPAPAAQSYLRYERILEAAVATGAQAIHP
GYGFLSENAEFAEACERENIVFIGPTPLQMGRFGRKHTARALAAENGVPLLPGTGLLIDLAEAHRQAAAIGYPVMLKSTA
GGGGIGLALCRGEAKLTESFQAVQRLSENNFRDGGVYLEKYVERARHLEVQIFGDGEGRVIALGERDCSIQRRNQKLLEE
TPAPGICETLRERLCEAAVCLGRAVGYRSAGTVEFIYDAEAADFYFLEVNTRLQVEHGVTEAVAGIDLVEWMVRLAAGER
DFLEQYRHRPRGHAVEVRLYAEDAGRNFQPSTGTLTEAVFAAVRCDGWVERGTEVTPYYDPLLAKLIVRGESRPEAIARL
QAALADTRIAGVETNLDYLRQILADADFLAGNLSTRFSQTFHYAPLTVEVLEPGTYSTIQDYPGRTGYWDIGVPPSGPMD
PLAFRLANRLVGNPPETAGLECTALGPTLRFHTDAVICLCGAAMDARIDSKPVSYWCAVPVAAGSTLRLGAVTGPGYRTY
LAVRGGFDVPEYLDSKATFTLGQFGGHCGRTLRTGDVLRLVRHDLADLPLPLAPALIPEYRSDWEIGVLYGPHGAPDFFT
DRDIETFFATAWEVHYNSARTGVRLIGPKPLWARSDGGEAGLHPSNIHDNAYAVGTVDFTGDMPVILGPDGPSLGGFVCP
ATVARAELWKIGQLKPGDTVRFRRLGFAEALRREQAQDFTIDRLSLPKPAAPSLAEAGDPAVLHTIAATAEQIAVVYRQS
GDKYLLIEYGPPVLDLNLRFRVHALMEWLQANALPGMLELTPGIRSLQVHFDGRILPRERLLEVLTAAESQLPPIEAMEV
PTRILHLPLSWEDESTLLAIRKYMQSVRKDAPWCPSNIEFIRRINGLESIDEVKRIVFEASYLVLGLGDVYLGAPVATPI
DPRHRLVTTKYNPARTWTPENAVGIGGAYLCIYGMEGPGGYQFVGRTVQVWNRYRQTADFTRPWLLRFFDQIRFYPVSGP
ELLRLREDFRHGRAKLEVSEAIFSLKQYNDFLAEIAPEAAAFKAQQQTAFAEERERWREAGEFAAVAEDPAIAPSAAEEY
ALPAGACAVSAQLSANVWQIAVQPGEPVAAGDPLVILESMKMEVVLTAPISGTVLAVLCAEGCLVAAGQTLVVVQPSESA
PP
>Mature_1202_residues
MFDKVLIANRGEIACRILRTLDRLGIASVAVYSEADAYAPHVRGAGEAVLIGPAPAAQSYLRYERILEAAVATGAQAIHP
GYGFLSENAEFAEACERENIVFIGPTPLQMGRFGRKHTARALAAENGVPLLPGTGLLIDLAEAHRQAAAIGYPVMLKSTA
GGGGIGLALCRGEAKLTESFQAVQRLSENNFRDGGVYLEKYVERARHLEVQIFGDGEGRVIALGERDCSIQRRNQKLLEE
TPAPGICETLRERLCEAAVCLGRAVGYRSAGTVEFIYDAEAADFYFLEVNTRLQVEHGVTEAVAGIDLVEWMVRLAAGER
DFLEQYRHRPRGHAVEVRLYAEDAGRNFQPSTGTLTEAVFAAVRCDGWVERGTEVTPYYDPLLAKLIVRGESRPEAIARL
QAALADTRIAGVETNLDYLRQILADADFLAGNLSTRFSQTFHYAPLTVEVLEPGTYSTIQDYPGRTGYWDIGVPPSGPMD
PLAFRLANRLVGNPPETAGLECTALGPTLRFHTDAVICLCGAAMDARIDSKPVSYWCAVPVAAGSTLRLGAVTGPGYRTY
LAVRGGFDVPEYLDSKATFTLGQFGGHCGRTLRTGDVLRLVRHDLADLPLPLAPALIPEYRSDWEIGVLYGPHGAPDFFT
DRDIETFFATAWEVHYNSARTGVRLIGPKPLWARSDGGEAGLHPSNIHDNAYAVGTVDFTGDMPVILGPDGPSLGGFVCP
ATVARAELWKIGQLKPGDTVRFRRLGFAEALRREQAQDFTIDRLSLPKPAAPSLAEAGDPAVLHTIAATAEQIAVVYRQS
GDKYLLIEYGPPVLDLNLRFRVHALMEWLQANALPGMLELTPGIRSLQVHFDGRILPRERLLEVLTAAESQLPPIEAMEV
PTRILHLPLSWEDESTLLAIRKYMQSVRKDAPWCPSNIEFIRRINGLESIDEVKRIVFEASYLVLGLGDVYLGAPVATPI
DPRHRLVTTKYNPARTWTPENAVGIGGAYLCIYGMEGPGGYQFVGRTVQVWNRYRQTADFTRPWLLRFFDQIRFYPVSGP
ELLRLREDFRHGRAKLEVSEAIFSLKQYNDFLAEIAPEAAAFKAQQQTAFAEERERWREAGEFAAVAEDPAIAPSAAEEY
ALPAGACAVSAQLSANVWQIAVQPGEPVAAGDPLVILESMKMEVVLTAPISGTVLAVLCAEGCLVAAGQTLVVVQPSESA
PP

Specific function: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA [H]

COG id: COG0439

COG function: function code I; Biotin carboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 biotin carboxylation domain [H]

Homologues:

Organism=Homo sapiens, GI116805327, Length=444, Percent_Identity=47.7477477477478, Blast_Score=410, Evalue=1e-114,
Organism=Homo sapiens, GI189095269, Length=442, Percent_Identity=45.2488687782805, Blast_Score=374, Evalue=1e-103,
Organism=Homo sapiens, GI65506442, Length=442, Percent_Identity=45.2488687782805, Blast_Score=374, Evalue=1e-103,
Organism=Homo sapiens, GI295821183, Length=442, Percent_Identity=45.2488687782805, Blast_Score=374, Evalue=1e-103,
Organism=Homo sapiens, GI106049528, Length=445, Percent_Identity=42.4719101123596, Blast_Score=329, Evalue=1e-89,
Organism=Homo sapiens, GI106049295, Length=445, Percent_Identity=42.4719101123596, Blast_Score=329, Evalue=1e-89,
Organism=Homo sapiens, GI106049292, Length=445, Percent_Identity=42.4719101123596, Blast_Score=329, Evalue=1e-89,
Organism=Homo sapiens, GI38679960, Length=500, Percent_Identity=31, Blast_Score=206, Evalue=9e-53,
Organism=Homo sapiens, GI38679974, Length=500, Percent_Identity=31, Blast_Score=206, Evalue=1e-52,
Organism=Homo sapiens, GI38679971, Length=500, Percent_Identity=31, Blast_Score=206, Evalue=1e-52,
Organism=Homo sapiens, GI38679977, Length=500, Percent_Identity=31, Blast_Score=206, Evalue=1e-52,
Organism=Homo sapiens, GI38679967, Length=500, Percent_Identity=31, Blast_Score=206, Evalue=1e-52,
Organism=Homo sapiens, GI134142062, Length=501, Percent_Identity=30.3393213572854, Blast_Score=200, Evalue=6e-51,
Organism=Escherichia coli, GI1789654, Length=444, Percent_Identity=46.8468468468468, Blast_Score=353, Evalue=4e-98,
Organism=Escherichia coli, GI1786930, Length=321, Percent_Identity=30.5295950155763, Blast_Score=111, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI71987519, Length=437, Percent_Identity=46.9107551487414, Blast_Score=375, Evalue=1e-104,
Organism=Caenorhabditis elegans, GI17567343, Length=442, Percent_Identity=43.6651583710407, Blast_Score=360, Evalue=2e-99,
Organism=Caenorhabditis elegans, GI17562816, Length=508, Percent_Identity=39.9606299212598, Blast_Score=332, Evalue=7e-91,
Organism=Caenorhabditis elegans, GI133931226, Length=483, Percent_Identity=29.1925465838509, Blast_Score=206, Evalue=8e-53,
Organism=Caenorhabditis elegans, GI71997168, Length=436, Percent_Identity=30.045871559633, Blast_Score=195, Evalue=1e-49,
Organism=Caenorhabditis elegans, GI71997163, Length=436, Percent_Identity=30.045871559633, Blast_Score=194, Evalue=3e-49,
Organism=Saccharomyces cerevisiae, GI6319685, Length=1206, Percent_Identity=45.4394693200663, Blast_Score=1112, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319695, Length=447, Percent_Identity=37.8076062639821, Blast_Score=274, Evalue=8e-74,
Organism=Saccharomyces cerevisiae, GI6321376, Length=446, Percent_Identity=38.1165919282511, Blast_Score=268, Evalue=6e-72,
Organism=Saccharomyces cerevisiae, GI6323863, Length=451, Percent_Identity=31.9290465631929, Blast_Score=207, Evalue=7e-54,
Organism=Saccharomyces cerevisiae, GI6324343, Length=525, Percent_Identity=29.7142857142857, Blast_Score=204, Evalue=7e-53,
Organism=Drosophila melanogaster, GI24651757, Length=439, Percent_Identity=46.6970387243736, Blast_Score=389, Evalue=1e-108,
Organism=Drosophila melanogaster, GI24651759, Length=402, Percent_Identity=46.0199004975124, Blast_Score=345, Evalue=9e-95,
Organism=Drosophila melanogaster, GI24652212, Length=457, Percent_Identity=42.4507658643326, Blast_Score=325, Evalue=2e-88,
Organism=Drosophila melanogaster, GI24652210, Length=457, Percent_Identity=42.4507658643326, Blast_Score=325, Evalue=2e-88,
Organism=Drosophila melanogaster, GI24652214, Length=457, Percent_Identity=42.4507658643326, Blast_Score=325, Evalue=2e-88,
Organism=Drosophila melanogaster, GI19921944, Length=457, Percent_Identity=42.4507658643326, Blast_Score=325, Evalue=2e-88,
Organism=Drosophila melanogaster, GI24652216, Length=457, Percent_Identity=42.4507658643326, Blast_Score=325, Evalue=2e-88,
Organism=Drosophila melanogaster, GI281363050, Length=457, Percent_Identity=42.4507658643326, Blast_Score=324, Evalue=2e-88,
Organism=Drosophila melanogaster, GI24652224, Length=457, Percent_Identity=42.4507658643326, Blast_Score=324, Evalue=2e-88,
Organism=Drosophila melanogaster, GI24652222, Length=457, Percent_Identity=42.4507658643326, Blast_Score=324, Evalue=2e-88,
Organism=Drosophila melanogaster, GI24652220, Length=457, Percent_Identity=42.4507658643326, Blast_Score=324, Evalue=2e-88,
Organism=Drosophila melanogaster, GI24652218, Length=457, Percent_Identity=42.4507658643326, Blast_Score=324, Evalue=2e-88,
Organism=Drosophila melanogaster, GI161076409, Length=495, Percent_Identity=31.1111111111111, Blast_Score=195, Evalue=1e-49,
Organism=Drosophila melanogaster, GI161076407, Length=495, Percent_Identity=31.1111111111111, Blast_Score=195, Evalue=1e-49,
Organism=Drosophila melanogaster, GI24586460, Length=495, Percent_Identity=31.1111111111111, Blast_Score=195, Evalue=1e-49,
Organism=Drosophila melanogaster, GI24586458, Length=495, Percent_Identity=31.1111111111111, Blast_Score=195, Evalue=2e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR011764
- InterPro:   IPR005482
- InterPro:   IPR005479
- InterPro:   IPR005481
- InterPro:   IPR013817
- InterPro:   IPR016185
- InterPro:   IPR011054 [H]

Pfam domain/function: PF02785 Biotin_carb_C; PF00289 CPSase_L_chain; PF02786 CPSase_L_D2 [H]

EC number: =6.3.4.14; =6.4.1.2 [H]

Molecular weight: Translated: 131225; Mature: 131225

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: PS50975 ATP_GRASP ; PS00866 CPSASE_1 ; PS00867 CPSASE_2 ; PS50979 BC ; PS50968 BIOTINYL_LIPOYL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDKVLIANRGEIACRILRTLDRLGIASVAVYSEADAYAPHVRGAGEAVLIGPAPAAQSY
CCCCEEEECCCHHHHHHHHHHHHCCHHHEEEECCCCCCCCCCCCCCCEEEECCCHHHHHH
LRYERILEAAVATGAQAIHPGYGFLSENAEFAEACERENIVFIGPTPLQMGRFGRKHTAR
HHHHHHHHHHHHCCCHHCCCCCCCCCCCCHHHHHHCCCCEEEECCCCHHHHCCCCHHHHH
ALAAENGVPLLPGTGLLIDLAEAHRQAAAIGYPVMLKSTAGGGGIGLALCRGEAKLTESF
HHHHCCCCCCCCCCCCEEEHHHHHHHHHHCCCCEEEEECCCCCCEEEEEECCCHHHHHHH
QAVQRLSENNFRDGGVYLEKYVERARHLEVQIFGDGEGRVIALGERDCSIQRRNQKLLEE
HHHHHHHHCCCCCCCHHHHHHHHHHHCEEEEEEECCCCCEEEECCCCCHHHHHHHHHHHH
TPAPGICETLRERLCEAAVCLGRAVGYRSAGTVEFIYDAEAADFYFLEVNTRLQVEHGVT
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEEEECCEEEECCCHH
EAVAGIDLVEWMVRLAAGERDFLEQYRHRPRGHAVEVRLYAEDAGRNFQPSTGTLTEAVF
HHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCEEEEEEEEECCCCCCCCCCCHHHHHHH
AAVRCDGWVERGTEVTPYYDPLLAKLIVRGESRPEAIARLQAALADTRIAGVETNLDYLR
HHHHCCHHHHCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHEECCCCCHHHHH
QILADADFLAGNLSTRFSQTFHYAPLTVEVLEPGTYSTIQDYPGRTGYWDIGVPPSGPMD
HHHCCCHHHHCCCHHHHHHCEEECCEEEEEECCCCCCHHHCCCCCCCEEECCCCCCCCCC
PLAFRLANRLVGNPPETAGLECTALGPTLRFHTDAVICLCGAAMDARIDSKPVSYWCAVP
HHHHHHHHHHCCCCCCCCCEEEEECCCEEEECCCEEEEEECCHHHCCCCCCCCEEEEEEE
VAAGSTLRLGAVTGPGYRTYLAVRGGFDVPEYLDSKATFTLGQFGGHCGRTLRTGDVLRL
ECCCCEEEEEEEECCCCEEEEEEECCCCCHHHHCCCCEEEHHHHCCCCCCCCCHHHHHHH
VRHDLADLPLPLAPALIPEYRSDWEIGVLYGPHGAPDFFTDRDIETFFATAWEVHYNSAR
HHHHHHHCCCCCCHHHHHCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHEEEEEEECCCC
TGVRLIGPKPLWARSDGGEAGLHPSNIHDNAYAVGTVDFTGDMPVILGPDGPSLGGFVCP
CCEEEECCCCCEECCCCCCCCCCCCCCCCCEEEEEEEEECCCCCEEECCCCCCCCCEECH
ATVARAELWKIGQLKPGDTVRFRRLGFAEALRREQAQDFTIDRLSLPKPAAPSLAEAGDP
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCHHHCCCC
AVLHTIAATAEQIAVVYRQSGDKYLLIEYGPPVLDLNLRFRVHALMEWLQANALPGMLEL
HHHHHHHHHHHHHHEEEECCCCEEEEEEECCCEEEEEEHHHHHHHHHHHHHCCCCCCEEE
TPGIRSLQVHFDGRILPRERLLEVLTAAESQLPPIEAMEVPTRILHLPLSWEDESTLLAI
CCCCEEEEEEECCEECCHHHHHHHHHHHHHCCCCCHHHHCCCEEEEECCCCCCCHHHHHH
RKYMQSVRKDAPWCPSNIEFIRRINGLESIDEVKRIVFEASYLVLGLGDVYLGAPVATPI
HHHHHHHHHCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHCEEEEEECCHHCCCCCCCCC
DPRHRLVTTKYNPARTWTPENAVGIGGAYLCIYGMEGPGGYQFVGRTVQVWNRYRQTADF
CCCCCEEEEECCCCCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCC
TRPWLLRFFDQIRFYPVSGPELLRLREDFRHGRAKLEVSEAIFSLKQYNDFLAEIAPEAA
CHHHHHHHHHHHEEEECCCHHHHHHHHHHHCCHHEEEHHHHHHHHHHHHHHHHHHCCHHH
AFKAQQQTAFAEERERWREAGEFAAVAEDPAIAPSAAEEYALPAGACAVSAQLSANVWQI
HHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCHHHHCCCCCHHEEEHCCCCCEEEE
AVQPGEPVAAGDPLVILESMKMEVVLTAPISGTVLAVLCAEGCLVAAGQTLVVVQPSESA
EECCCCCCCCCCCEEEEECCCEEEEEECCCCHHHHHHHHHCCCEEECCCEEEEEECCCCC
PP
CC
>Mature Secondary Structure
MFDKVLIANRGEIACRILRTLDRLGIASVAVYSEADAYAPHVRGAGEAVLIGPAPAAQSY
CCCCEEEECCCHHHHHHHHHHHHCCHHHEEEECCCCCCCCCCCCCCCEEEECCCHHHHHH
LRYERILEAAVATGAQAIHPGYGFLSENAEFAEACERENIVFIGPTPLQMGRFGRKHTAR
HHHHHHHHHHHHCCCHHCCCCCCCCCCCCHHHHHHCCCCEEEECCCCHHHHCCCCHHHHH
ALAAENGVPLLPGTGLLIDLAEAHRQAAAIGYPVMLKSTAGGGGIGLALCRGEAKLTESF
HHHHCCCCCCCCCCCCEEEHHHHHHHHHHCCCCEEEEECCCCCCEEEEEECCCHHHHHHH
QAVQRLSENNFRDGGVYLEKYVERARHLEVQIFGDGEGRVIALGERDCSIQRRNQKLLEE
HHHHHHHHCCCCCCCHHHHHHHHHHHCEEEEEEECCCCCEEEECCCCCHHHHHHHHHHHH
TPAPGICETLRERLCEAAVCLGRAVGYRSAGTVEFIYDAEAADFYFLEVNTRLQVEHGVT
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEEEECCEEEECCCHH
EAVAGIDLVEWMVRLAAGERDFLEQYRHRPRGHAVEVRLYAEDAGRNFQPSTGTLTEAVF
HHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCEEEEEEEEECCCCCCCCCCCHHHHHHH
AAVRCDGWVERGTEVTPYYDPLLAKLIVRGESRPEAIARLQAALADTRIAGVETNLDYLR
HHHHCCHHHHCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHEECCCCCHHHHH
QILADADFLAGNLSTRFSQTFHYAPLTVEVLEPGTYSTIQDYPGRTGYWDIGVPPSGPMD
HHHCCCHHHHCCCHHHHHHCEEECCEEEEEECCCCCCHHHCCCCCCCEEECCCCCCCCCC
PLAFRLANRLVGNPPETAGLECTALGPTLRFHTDAVICLCGAAMDARIDSKPVSYWCAVP
HHHHHHHHHHCCCCCCCCCEEEEECCCEEEECCCEEEEEECCHHHCCCCCCCCEEEEEEE
VAAGSTLRLGAVTGPGYRTYLAVRGGFDVPEYLDSKATFTLGQFGGHCGRTLRTGDVLRL
ECCCCEEEEEEEECCCCEEEEEEECCCCCHHHHCCCCEEEHHHHCCCCCCCCCHHHHHHH
VRHDLADLPLPLAPALIPEYRSDWEIGVLYGPHGAPDFFTDRDIETFFATAWEVHYNSAR
HHHHHHHCCCCCCHHHHHCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHEEEEEEECCCC
TGVRLIGPKPLWARSDGGEAGLHPSNIHDNAYAVGTVDFTGDMPVILGPDGPSLGGFVCP
CCEEEECCCCCEECCCCCCCCCCCCCCCCCEEEEEEEEECCCCCEEECCCCCCCCCEECH
ATVARAELWKIGQLKPGDTVRFRRLGFAEALRREQAQDFTIDRLSLPKPAAPSLAEAGDP
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCHHHCCCC
AVLHTIAATAEQIAVVYRQSGDKYLLIEYGPPVLDLNLRFRVHALMEWLQANALPGMLEL
HHHHHHHHHHHHHHEEEECCCCEEEEEEECCCEEEEEEHHHHHHHHHHHHHCCCCCCEEE
TPGIRSLQVHFDGRILPRERLLEVLTAAESQLPPIEAMEVPTRILHLPLSWEDESTLLAI
CCCCEEEEEEECCEECCHHHHHHHHHHHHHCCCCCHHHHCCCEEEEECCCCCCCHHHHHH
RKYMQSVRKDAPWCPSNIEFIRRINGLESIDEVKRIVFEASYLVLGLGDVYLGAPVATPI
HHHHHHHHHCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHCEEEEEECCHHCCCCCCCCC
DPRHRLVTTKYNPARTWTPENAVGIGGAYLCIYGMEGPGGYQFVGRTVQVWNRYRQTADF
CCCCCEEEEECCCCCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCC
TRPWLLRFFDQIRFYPVSGPELLRLREDFRHGRAKLEVSEAIFSLKQYNDFLAEIAPEAA
CHHHHHHHHHHHEEEECCCHHHHHHHHHHHCCHHEEEHHHHHHHHHHHHHHHHHHCCHHH
AFKAQQQTAFAEERERWREAGEFAAVAEDPAIAPSAAEEYALPAGACAVSAQLSANVWQI
HHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCHHHHCCCCCHHEEEHCCCCCEEEE
AVQPGEPVAAGDPLVILESMKMEVVLTAPISGTVLAVLCAEGCLVAAGQTLVVVQPSESA
EECCCCCCCCCCCEEEEECCCEEEEEECCCCHHHHHHHHHCCCEEECCCEEEEEECCCCC
PP
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]