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The map label for this gene is 37520523

Identifier: 37520523

GI number: 37520523

Start: 1010755

End: 1011855

Strand: Direct

Name: 37520523

Synonym: glr0954

Alternate gene names: NA

Gene position: 1010755-1011855 (Clockwise)

Preceding gene: 37520521

Following gene: 37520524

Centisome position: 21.69

GC content: 62.76

Gene sequence:

>1101_bases
GTGGCCGACTGCCATACACAATGCAAAATATGTCGTTCCGGCGACATGGCCACCGGGTCGCGTAGCAGGTGTGCGGGAAG
CGACAGTTCTTTCTTCTCGCCGAAACCACTACAATGCCCTCACCGATTTCCTGAGGGAGAAGTCATGGACACTTTGCACA
CCCGGCGGGCGAGTGGCCCGCCGGTCTGGAGTTCTTTATTCGCATTGGCATTTGTAGTAGCCGCTTCTGGCCTGGGGACA
CCTGCCGCTCTGGCGCAAGCGCTCTCCCCGGCCAATGCCCAGAGGCTCTATGTCTTTGGCGACAGCCTTGTCGATCTCGG
CAATGTCTTCATCATTTCGAGAGGAACCTTTCCTCCCAGTCCGCCGTACTTCGAGGGCCGCCTGTCCAACGGCCCGCTGT
GGATCGAAGATCTGGCCGCCCGGCTGAACCTGCCTTTGCAACCCAGTCTTGAAGGGGGCACCGGCTACGCTTTTGGAGGT
GCAACGACGGGCTTCAAGCCGTCGCAACCCCCGCCGCCCGGGATTCCCCCCGGCATTCCGGGCGTGCTTGCCCAGGTGGC
CACTTTCGCCGAAACCCGGCCGCCGGTGGCCCCGGAGGATCTGTTTTTTGTCGTGGCGGGTTCCAACGACATCTTGCTTT
TCGGCGAGAGCGATATTGACCTGTTGCTCGACAACGTCGCCACGGCCCTTTCGGAACTTTACGCCCAGGGGGCGCGGACC
ATCGTCGTGACCAACCTGCCGCCTCTATCCAGAACGCCCCTGGCGGGTTCCGACCCCCAGCAGGTTGCCGCTTTGGGCGT
GCTGACGCGGACCTACAACCGCAAGCTGGAACGCCGGTTGCAGCTGTTGGAGCAAACCCAACCCGGTCTCAAGCCGATCT
TGCTCGACGCCTACGCTTTGGTGCTGGCGCTCATCGACAACCCGGCCCGCTTCGGGCTCACCAACGTCACCGAGCCCTGT
CTGACAGAAACCGCGGTCTGCCCCGATCCAGAGCAATACCTGTTTTGGGACGAAGTGCACCCCACCGCTGCCGTCGGCCG
CATCCTCGCCGATTACGCCTATGCCGTGCTGGCGCGCTCCACACTGCCGGCGGCCAGATGA

Upstream 100 bases:

>100_bases
GCAGGCCAAGCCGGACAGAAGCGGCAACGGATGACATCTCATCTTGACAATCTCCCAAGTAAGGCGTCCCTTCGAGGAGT
CTACCGCGGTTAGGCGCCCG

Downstream 100 bases:

>100_bases
CCCTTAGGGTAGCCGACGCACCTCGCACGTTTGTCAAATTTCCCGGTGCGCGCGGGCGACACCGAGCAAGGACTGCAGGG
CAGGGCGTTCATCGTTTTCT

Product: esterase

Products: NA

Alternate protein names: Glycerophospholipid-cholesterol acyltransferase; GCAT [H]

Number of amino acids: Translated: 366; Mature: 365

Protein sequence:

>366_residues
MADCHTQCKICRSGDMATGSRSRCAGSDSSFFSPKPLQCPHRFPEGEVMDTLHTRRASGPPVWSSLFALAFVVAASGLGT
PAALAQALSPANAQRLYVFGDSLVDLGNVFIISRGTFPPSPPYFEGRLSNGPLWIEDLAARLNLPLQPSLEGGTGYAFGG
ATTGFKPSQPPPPGIPPGIPGVLAQVATFAETRPPVAPEDLFFVVAGSNDILLFGESDIDLLLDNVATALSELYAQGART
IVVTNLPPLSRTPLAGSDPQQVAALGVLTRTYNRKLERRLQLLEQTQPGLKPILLDAYALVLALIDNPARFGLTNVTEPC
LTETAVCPDPEQYLFWDEVHPTAAVGRILADYAYAVLARSTLPAAR

Sequences:

>Translated_366_residues
MADCHTQCKICRSGDMATGSRSRCAGSDSSFFSPKPLQCPHRFPEGEVMDTLHTRRASGPPVWSSLFALAFVVAASGLGT
PAALAQALSPANAQRLYVFGDSLVDLGNVFIISRGTFPPSPPYFEGRLSNGPLWIEDLAARLNLPLQPSLEGGTGYAFGG
ATTGFKPSQPPPPGIPPGIPGVLAQVATFAETRPPVAPEDLFFVVAGSNDILLFGESDIDLLLDNVATALSELYAQGART
IVVTNLPPLSRTPLAGSDPQQVAALGVLTRTYNRKLERRLQLLEQTQPGLKPILLDAYALVLALIDNPARFGLTNVTEPC
LTETAVCPDPEQYLFWDEVHPTAAVGRILADYAYAVLARSTLPAAR
>Mature_365_residues
ADCHTQCKICRSGDMATGSRSRCAGSDSSFFSPKPLQCPHRFPEGEVMDTLHTRRASGPPVWSSLFALAFVVAASGLGTP
AALAQALSPANAQRLYVFGDSLVDLGNVFIISRGTFPPSPPYFEGRLSNGPLWIEDLAARLNLPLQPSLEGGTGYAFGGA
TTGFKPSQPPPPGIPPGIPGVLAQVATFAETRPPVAPEDLFFVVAGSNDILLFGESDIDLLLDNVATALSELYAQGARTI
VVTNLPPLSRTPLAGSDPQQVAALGVLTRTYNRKLERRLQLLEQTQPGLKPILLDAYALVLALIDNPARFGLTNVTEPCL
TETAVCPDPEQYLFWDEVHPTAAVGRILADYAYAVLARSTLPAAR

Specific function: Fatty acid transfer between phosphatidylcholine and cholesterol [H]

COG id: COG3240

COG function: function code IR; Phospholipase/lecithinase/hemolysin

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'GDSL' lipolytic enzyme family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013830
- InterPro:   IPR013831
- InterPro:   IPR001087
- InterPro:   IPR008265 [H]

Pfam domain/function: PF00657 Lipase_GDSL [H]

EC number: =2.3.1.43 [H]

Molecular weight: Translated: 38950; Mature: 38819

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADCHTQCKICRSGDMATGSRSRCAGSDSSFFSPKPLQCPHRFPEGEVMDTLHTRRASGP
CCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCC
PVWSSLFALAFVVAASGLGTPAALAQALSPANAQRLYVFGDSLVDLGNVFIISRGTFPPS
HHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCEEEEECCCHHCCCCEEEEECCCCCCC
PPYFEGRLSNGPLWIEDLAARLNLPLQPSLEGGTGYAFGGATTGFKPSQPPPPGIPPGIP
CCCCCCCCCCCCEEHHHHHHHHCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCH
GVLAQVATFAETRPPVAPEDLFFVVAGSNDILLFGESDIDLLLDNVATALSELYAQGART
HHHHHHHHHHHCCCCCCCCCEEEEEECCCCEEEECCCCHHHHHHHHHHHHHHHHHCCCCE
IVVTNLPPLSRTPLAGSDPQQVAALGVLTRTYNRKLERRLQLLEQTQPGLKPILLDAYAL
EEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
VLALIDNPARFGLTNVTEPCLTETAVCPDPEQYLFWDEVHPTAAVGRILADYAYAVLARS
HHHHHCCCHHCCCCCCCCHHHHCCCCCCCCHHEEEECCCCHHHHHHHHHHHHHHHHHHHH
TLPAAR
CCCCCC
>Mature Secondary Structure 
ADCHTQCKICRSGDMATGSRSRCAGSDSSFFSPKPLQCPHRFPEGEVMDTLHTRRASGP
CCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCC
PVWSSLFALAFVVAASGLGTPAALAQALSPANAQRLYVFGDSLVDLGNVFIISRGTFPPS
HHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCEEEEECCCHHCCCCEEEEECCCCCCC
PPYFEGRLSNGPLWIEDLAARLNLPLQPSLEGGTGYAFGGATTGFKPSQPPPPGIPPGIP
CCCCCCCCCCCCEEHHHHHHHHCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCH
GVLAQVATFAETRPPVAPEDLFFVVAGSNDILLFGESDIDLLLDNVATALSELYAQGART
HHHHHHHHHHHCCCCCCCCCEEEEEECCCCEEEECCCCHHHHHHHHHHHHHHHHHCCCCE
IVVTNLPPLSRTPLAGSDPQQVAALGVLTRTYNRKLERRLQLLEQTQPGLKPILLDAYAL
EEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
VLALIDNPARFGLTNVTEPCLTETAVCPDPEQYLFWDEVHPTAAVGRILADYAYAVLARS
HHHHHCCCHHCCCCCCCCHHHHCCCCCCCCHHEEEECCCCHHHHHHHHHHHHHHHHHHHH
TLPAAR
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2271578; 3280033; 1985976; 8294469 [H]