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The map label for this gene is nagA [H]

Identifier: 37520503

GI number: 37520503

Start: 990287

End: 991480

Strand: Reverse

Name: nagA [H]

Synonym: gll0934

Alternate gene names: 37520503

Gene position: 991480-990287 (Counterclockwise)

Preceding gene: 37520506

Following gene: 37520502

Centisome position: 21.28

GC content: 68.01

Gene sequence:

>1194_bases
ATGGCGGGCGGAAAAGTGAGAATGACGCGCTTGCGCATTGGTTACACTCTACTCAGCGAGGGGCTCGACAGGATGCGGCA
GATACGCAACGCCCGCTGGGCGGGAGACGGGAATCTCTACAGTCTACTGGTGGCCGAGGGACAACTGCAGGCGGTGGACC
CATCGGGCGACTGCTGGGAAGGGAGCGCCGACTCGATCGATCTGGCGGGAGCCTGGGTGAGCCCGGGGCTGGTGGATCTG
CAGCTCAACGGCGCTCTGGGGGTCGAATTTTCGGAACTGGAAGGCGACGAGGGCCTGGAGCAACTGGGGCGCATCTCGAC
CTATCTCTGGTCGATTGGCCTCTCGGCCTGGTTGCCCACCTTGATCAGCGTCCCGGTCGAAAAGCTGCAGGGAGCCCTCG
CGGTGATTGGCCGCTTTCGGCCCCCCAAAAGCGGCGCGCGCATCCTGGGGGTGCACCTCGAAGGACCGTTTCTCAACCCC
GAGTACGAAGGCGCCCACATGCGCCGGTACCTGCTGCCGCTCACCGTCGAAGACGCCAAGTGCGTCCTGGGGGATTACGC
CTCCCTGGTGAAGCTCGTCACCCTCGCCCCCGAACTCGACCCGGACGGCCAGACGATCCCCTGGCTGGTCGCCCAGGGCA
TCCACGTGAGCCTCGGCCACACCGCCGCCACCTTCGAGCAGGCGCAGCGGGCCTTCGACGCGGGGGCGCGGCTGGTGACC
CATATTTTTAATGCCCAGCGCCCCTTCCACCACCGCGAGCCCGGCGTGGTGGGGGCGGCTTTGCTGGATGAGCGGGTGCA
ATGCCTGTGCATTCCCGACGGCATCCACCTGCACCCGGCTGCCACCCAATTGCTGCTGCGCGCCAAGGGCGAAGCGGGCC
TCATCCCGGTGAGCGATGCGGTGGCACCCTTGGGAATCGCCGACGGTCGCTACGACTGGCATGGCCTCGCCATTACCGTG
CGCGCCGGGCAGGTGACCCTCGAAGACGGTCGGCTCGCCGGTAGCGCCCTCAGCCTCACCGATGTACTGGCGCGGCTGGT
GGGCCAGTGCGGGGTCGATCCGGGCGTGGCCCTGCGCCTGGGGGCGCTCCAGCCGCGGCGGGTCCTGGGCGAACCGGTCG
ATTGGCCGCCGGATGCCGATTTGCTGGTGTGGCCCCCGGGCAAAGACCGGCCCGAGCGCTTGGAGGTACGATGA

Upstream 100 bases:

>100_bases
CACCAGTTTGCCCACTTCGTCGGGGGCCACCTGGGCGCGCAGGATGTTGCTCGCGATGTTGAAATCCTTGGCCAGCCGGT
AGGTGACCGGCATATGCACG

Downstream 100 bases:

>100_bases
GCCCCCCCGCCGAACGCCTGCGCGAGTTTCGCTGGCGCGTCTTCAACATCGTGATGGCGATCGTCGGACTCTACGTGGTC
GGCGTGATCGGCTACATGGT

Product: N-acetyl-glucosamine-6-phosphate deacetylase

Products: NA

Alternate protein names: GlcNAc 6-P deacetylase [H]

Number of amino acids: Translated: 397; Mature: 396

Protein sequence:

>397_residues
MAGGKVRMTRLRIGYTLLSEGLDRMRQIRNARWAGDGNLYSLLVAEGQLQAVDPSGDCWEGSADSIDLAGAWVSPGLVDL
QLNGALGVEFSELEGDEGLEQLGRISTYLWSIGLSAWLPTLISVPVEKLQGALAVIGRFRPPKSGARILGVHLEGPFLNP
EYEGAHMRRYLLPLTVEDAKCVLGDYASLVKLVTLAPELDPDGQTIPWLVAQGIHVSLGHTAATFEQAQRAFDAGARLVT
HIFNAQRPFHHREPGVVGAALLDERVQCLCIPDGIHLHPAATQLLLRAKGEAGLIPVSDAVAPLGIADGRYDWHGLAITV
RAGQVTLEDGRLAGSALSLTDVLARLVGQCGVDPGVALRLGALQPRRVLGEPVDWPPDADLLVWPPGKDRPERLEVR

Sequences:

>Translated_397_residues
MAGGKVRMTRLRIGYTLLSEGLDRMRQIRNARWAGDGNLYSLLVAEGQLQAVDPSGDCWEGSADSIDLAGAWVSPGLVDL
QLNGALGVEFSELEGDEGLEQLGRISTYLWSIGLSAWLPTLISVPVEKLQGALAVIGRFRPPKSGARILGVHLEGPFLNP
EYEGAHMRRYLLPLTVEDAKCVLGDYASLVKLVTLAPELDPDGQTIPWLVAQGIHVSLGHTAATFEQAQRAFDAGARLVT
HIFNAQRPFHHREPGVVGAALLDERVQCLCIPDGIHLHPAATQLLLRAKGEAGLIPVSDAVAPLGIADGRYDWHGLAITV
RAGQVTLEDGRLAGSALSLTDVLARLVGQCGVDPGVALRLGALQPRRVLGEPVDWPPDADLLVWPPGKDRPERLEVR
>Mature_396_residues
AGGKVRMTRLRIGYTLLSEGLDRMRQIRNARWAGDGNLYSLLVAEGQLQAVDPSGDCWEGSADSIDLAGAWVSPGLVDLQ
LNGALGVEFSELEGDEGLEQLGRISTYLWSIGLSAWLPTLISVPVEKLQGALAVIGRFRPPKSGARILGVHLEGPFLNPE
YEGAHMRRYLLPLTVEDAKCVLGDYASLVKLVTLAPELDPDGQTIPWLVAQGIHVSLGHTAATFEQAQRAFDAGARLVTH
IFNAQRPFHHREPGVVGAALLDERVQCLCIPDGIHLHPAATQLLLRAKGEAGLIPVSDAVAPLGIADGRYDWHGLAITVR
AGQVTLEDGRLAGSALSLTDVLARLVGQCGVDPGVALRLGALQPRRVLGEPVDWPPDADLLVWPPGKDRPERLEVR

Specific function: N-acetylglucosamine utilization. [C]

COG id: COG1820

COG function: function code G; N-acetylglucosamine-6-phosphate deacetylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nagA family [H]

Homologues:

Organism=Homo sapiens, GI21361513, Length=300, Percent_Identity=36.3333333333333, Blast_Score=160, Evalue=1e-39,
Organism=Homo sapiens, GI224922791, Length=252, Percent_Identity=38.4920634920635, Blast_Score=159, Evalue=3e-39,
Organism=Escherichia coli, GI1786892, Length=333, Percent_Identity=33.9339339339339, Blast_Score=166, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI17553768, Length=376, Percent_Identity=31.3829787234043, Blast_Score=162, Evalue=4e-40,
Organism=Drosophila melanogaster, GI19920392, Length=378, Percent_Identity=33.5978835978836, Blast_Score=173, Evalue=2e-43,
Organism=Drosophila melanogaster, GI281361140, Length=390, Percent_Identity=32.5641025641026, Blast_Score=170, Evalue=2e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR003764
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.1.25 [H]

Molecular weight: Translated: 42677; Mature: 42545

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGGKVRMTRLRIGYTLLSEGLDRMRQIRNARWAGDGNLYSLLVAEGQLQAVDPSGDCWE
CCCCEEEEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCEEEEECCCCCCCC
GSADSIDLAGAWVSPGLVDLQLNGALGVEFSELEGDEGLEQLGRISTYLWSIGLSAWLPT
CCCCCEEECEEECCCCEEEEEECCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LISVPVEKLQGALAVIGRFRPPKSGARILGVHLEGPFLNPEYEGAHMRRYLLPLTVEDAK
HHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCCCCCCHHEEEEEEEEECCCH
CVLGDYASLVKLVTLAPELDPDGQTIPWLVAQGIHVSLGHTAATFEQAQRAFDAGARLVT
HHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCEEEECCCHHHHHHHHHHHHHHHHHHHH
HIFNAQRPFHHREPGVVGAALLDERVQCLCIPDGIHLHPAATQLLLRAKGEAGLIPVSDA
HHHHCCCCCCCCCCCCCHHHHHHCCCEEEEECCCCEECHHHHHHHHHCCCCCCEEECCCC
VAPLGIADGRYDWHGLAITVRAGQVTLEDGRLAGSALSLTDVLARLVGQCGVDPGVALRL
CCCCCCCCCCCEEEEEEEEEEECEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEE
GALQPRRVLGEPVDWPPDADLLVWPPGKDRPERLEVR
CCCCCHHHHCCCCCCCCCCCEEEECCCCCCCCCCCCC
>Mature Secondary Structure 
AGGKVRMTRLRIGYTLLSEGLDRMRQIRNARWAGDGNLYSLLVAEGQLQAVDPSGDCWE
CCCEEEEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCEEEEECCCCCCCC
GSADSIDLAGAWVSPGLVDLQLNGALGVEFSELEGDEGLEQLGRISTYLWSIGLSAWLPT
CCCCCEEECEEECCCCEEEEEECCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LISVPVEKLQGALAVIGRFRPPKSGARILGVHLEGPFLNPEYEGAHMRRYLLPLTVEDAK
HHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCCCCCCHHEEEEEEEEECCCH
CVLGDYASLVKLVTLAPELDPDGQTIPWLVAQGIHVSLGHTAATFEQAQRAFDAGARLVT
HHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCEEEECCCHHHHHHHHHHHHHHHHHHHH
HIFNAQRPFHHREPGVVGAALLDERVQCLCIPDGIHLHPAATQLLLRAKGEAGLIPVSDA
HHHHCCCCCCCCCCCCCHHHHHHCCCEEEEECCCCEECHHHHHHHHHCCCCCCEEECCCC
VAPLGIADGRYDWHGLAITVRAGQVTLEDGRLAGSALSLTDVLARLVGQCGVDPGVALRL
CCCCCCCCCCCEEEEEEEEEEECEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEE
GALQPRRVLGEPVDWPPDADLLVWPPGKDRPERLEVR
CCCCCHHHHCCCCCCCCCCCEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9301118; 10952301 [H]