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The map label for this gene is btuB [H]

Identifier: 37520465

GI number: 37520465

Start: 950578

End: 952872

Strand: Reverse

Name: btuB [H]

Synonym: gll0896

Alternate gene names: 37520465

Gene position: 952872-950578 (Counterclockwise)

Preceding gene: 37520466

Following gene: 37520462

Centisome position: 20.45

GC content: 62.22

Gene sequence:

>2295_bases
ATGCGCTTTCAGGTCTGGGTGTTAGGTTTGGGTCTTGTTCTAGGCAACCCGCCTGTCCACGCCGAGCACGTTCCCACCAA
AAACGAGTTGCAGCGGCAGGAAGCAGGCATCCGAACACTGGCCCAAGCCCTGGAGCCACCGGCAGTCAGCGTCTCCCAGG
CTCCCCCGGACGAAACGGCGATCGAATCGATCGGGCCGGCGGGCAGCTATAGCCTCGACGAGGTCACCGTCACCGGCACC
CTCCGGCCGGCGCGCACCAACGAGACTTCCACCACGGTCTACACCGTCGATCGCAAAGAAATCGAGGACAAAGGCGCCAA
CAGCGTCGGCGAAGCGATCCGCGGCGTGCCCGGCGTGCAGTCGAACGTCTTCGGAGCGGGTGCCGATGTACACAACAACT
TTTTTATCCGCGGCCTGCCGAATCTCGGTATCGGCATCCTGGTGGACGGGCGGCTGATTACCAACCTCAACCAGGAACAC
TTTGATCTGAGCGATCTGCCGGTCTACAACACCGAGCGCATCGAGGTGCTCACCGGCAGCGGCACGACGCTCTACGGCAC
CAACGCGGCGGGCGGGGTGATCAACGTCATCACCCGCAAGCCGACCGGCCCGCTCGAAGCGGACCTCAAAGTCGAGTTCG
GCGGCTACGGCTACAGCAACTACAGCGCAAGCTACGGCGGCAAAGTCGACAAATTCGGTTTTCGCGCTGGCTACCGCCAA
TTCGACACCAACGACGATTATTACTACCAGGTCCAGCGGCCGACAACGGGGCTTTTTACCGGCAACCGCCCCAACGCCTA
CCAGCACGCCAAATTTTACGACCTCAATTTGAGCTACGACTTTGACGATCGCAACCGCCTGCGCCTCGACGGCTACTTGC
GGGGCAGCACGCGGGGAATAGCTCCTTTTTCGATTTTCGATCCGGCCAGGCCCTTTCTCGATTCGGCCACGGGCGAGCCG
CAGTTCGAGATTACCCGCCTGGTCACCCAGGCGAACGGCCTCGCCCTCACCTACGACAGCGACCTGGGCCAGGCGCGCGA
CTCGAAGCTGCAGGTACTCGCAGCCGTCGATCGCAATCTGGTGGAAGAATTTTCGGGCGTCGACCTGGGCGATCCGGGTA
CCTACACCGACATCTCCGTCTTGAACTTTCAGGTCCGCCACAACTGGCAGTTCAATCCGACCAACAACATCACCTACGGC
TTCGAGTACCAGCGCCAATTTGGCCGCTCGGGCGAAAACAGCGGTGAGATCACCAGCTTCGATACCGGCCAGGATCTGCC
GGCCCTCTTTGCCCTGTACACCTGGAAACCGCTCGAACCGCTGGTGATCACCGCCGGTGTGCGCGCCACTTTTGTGGGCA
ATATCGTGGCGCGCGGCCTGGTGCGCGATATTCCCAGTTCCGTCGACCCGTCGGTGGGTTTTCGCTACCAGCTGTTGCCG
GGACTAGCTCTGCGCGGCAACTACCAGCGCATCTACCGCGCCCCCAACTTTAACGATCTCTTTGGCCGCACCACCCACAT
CGGCAACCCGTTTTTGGAGCCCGAATCGGGCAACGCCTTCGACATCGGCCTTGACTGGCAGACCGGGGGCACCAGCTTAC
TGCGGCTCACTTACTTCACCGCCGATGTCAATAACCTCACCGACTACCTGCTGGTGCGCAACGCCTGCGATCTGAACGGC
AATGCCCCCGACTGCAACGACGACCCGCGCAGCAATGCCGAGCGCTTTCGGGTCAATTACCCGCGCGTCAATTCCTCCGG
CCTGGAGGCCGCCTTCAACTGGAAGATCGCCTCCGAGTGGAGTACTTTTGCCACCACAACCCTGGTCGATTCGCGTCTGG
TGGCCGCCCCCGATCCGGCCACCGTCAACAACCAGCTGGTGCAGCTCGGCAGCATCAACAACTCCGAGGACGGCACCTTT
CGTGTCGATGTGGCCGAGCGCAACGCCCTGGTGCAGACCCAGTACCCGCTGGTGCCTTTTTTGACCTCCCGATTGGGGGT
CACCTACGAGCCGCCCGGCGGGTTGCGGGCCAGCCTCTTTGCCAACATTTCGGGGGGCCGATCGGTGGATGTCAACCACG
TCGGCCCCTTCGACACGCTGCACCCGGCCCGCCTCACCCCCGGTTCGCTGCTGCCCGGCTACACCACCGTCGATATGTCC
GTACGGGTTCCCCTCACCCCGTCCGTGGCCCTGAACGGATACGTGTTCAACCTGTTCAACAGCTACTACGAGCGCTCCTA
CGGCAACCCCGGGCCGGGGATTAACTTTCGGGTGGGGCTTTCGAGCACGTTTTAA

Upstream 100 bases:

>100_bases
CAATTTGTAGCACCGCTGGGATTGTGCGATGCCCCCCGGAGGGATATCGCTAACGGTCTAGCGGATTGTTCAATCGACAG
TACTTGCCGAGGAGTTTGTC

Downstream 100 bases:

>100_bases
GCGCCCGTCATGGCGTGACCAAAAAGCGGTTGTGGCTGGCGGCACTCCCGGCTGTGGTGGTCACCTTCACCCGGCCGCTG
AGCGCCCCCACCGGCACAGT

Product: hypothetical protein

Products: NA

Alternate protein names: Cobalamin receptor; Outer membrane cobalamin translocator [H]

Number of amino acids: Translated: 764; Mature: 764

Protein sequence:

>764_residues
MRFQVWVLGLGLVLGNPPVHAEHVPTKNELQRQEAGIRTLAQALEPPAVSVSQAPPDETAIESIGPAGSYSLDEVTVTGT
LRPARTNETSTTVYTVDRKEIEDKGANSVGEAIRGVPGVQSNVFGAGADVHNNFFIRGLPNLGIGILVDGRLITNLNQEH
FDLSDLPVYNTERIEVLTGSGTTLYGTNAAGGVINVITRKPTGPLEADLKVEFGGYGYSNYSASYGGKVDKFGFRAGYRQ
FDTNDDYYYQVQRPTTGLFTGNRPNAYQHAKFYDLNLSYDFDDRNRLRLDGYLRGSTRGIAPFSIFDPARPFLDSATGEP
QFEITRLVTQANGLALTYDSDLGQARDSKLQVLAAVDRNLVEEFSGVDLGDPGTYTDISVLNFQVRHNWQFNPTNNITYG
FEYQRQFGRSGENSGEITSFDTGQDLPALFALYTWKPLEPLVITAGVRATFVGNIVARGLVRDIPSSVDPSVGFRYQLLP
GLALRGNYQRIYRAPNFNDLFGRTTHIGNPFLEPESGNAFDIGLDWQTGGTSLLRLTYFTADVNNLTDYLLVRNACDLNG
NAPDCNDDPRSNAERFRVNYPRVNSSGLEAAFNWKIASEWSTFATTTLVDSRLVAAPDPATVNNQLVQLGSINNSEDGTF
RVDVAERNALVQTQYPLVPFLTSRLGVTYEPPGGLRASLFANISGGRSVDVNHVGPFDTLHPARLTPGSLLPGYTTVDMS
VRVPLTPSVALNGYVFNLFNSYYERSYGNPGPGINFRVGLSSTF

Sequences:

>Translated_764_residues
MRFQVWVLGLGLVLGNPPVHAEHVPTKNELQRQEAGIRTLAQALEPPAVSVSQAPPDETAIESIGPAGSYSLDEVTVTGT
LRPARTNETSTTVYTVDRKEIEDKGANSVGEAIRGVPGVQSNVFGAGADVHNNFFIRGLPNLGIGILVDGRLITNLNQEH
FDLSDLPVYNTERIEVLTGSGTTLYGTNAAGGVINVITRKPTGPLEADLKVEFGGYGYSNYSASYGGKVDKFGFRAGYRQ
FDTNDDYYYQVQRPTTGLFTGNRPNAYQHAKFYDLNLSYDFDDRNRLRLDGYLRGSTRGIAPFSIFDPARPFLDSATGEP
QFEITRLVTQANGLALTYDSDLGQARDSKLQVLAAVDRNLVEEFSGVDLGDPGTYTDISVLNFQVRHNWQFNPTNNITYG
FEYQRQFGRSGENSGEITSFDTGQDLPALFALYTWKPLEPLVITAGVRATFVGNIVARGLVRDIPSSVDPSVGFRYQLLP
GLALRGNYQRIYRAPNFNDLFGRTTHIGNPFLEPESGNAFDIGLDWQTGGTSLLRLTYFTADVNNLTDYLLVRNACDLNG
NAPDCNDDPRSNAERFRVNYPRVNSSGLEAAFNWKIASEWSTFATTTLVDSRLVAAPDPATVNNQLVQLGSINNSEDGTF
RVDVAERNALVQTQYPLVPFLTSRLGVTYEPPGGLRASLFANISGGRSVDVNHVGPFDTLHPARLTPGSLLPGYTTVDMS
VRVPLTPSVALNGYVFNLFNSYYERSYGNPGPGINFRVGLSSTF
>Mature_764_residues
MRFQVWVLGLGLVLGNPPVHAEHVPTKNELQRQEAGIRTLAQALEPPAVSVSQAPPDETAIESIGPAGSYSLDEVTVTGT
LRPARTNETSTTVYTVDRKEIEDKGANSVGEAIRGVPGVQSNVFGAGADVHNNFFIRGLPNLGIGILVDGRLITNLNQEH
FDLSDLPVYNTERIEVLTGSGTTLYGTNAAGGVINVITRKPTGPLEADLKVEFGGYGYSNYSASYGGKVDKFGFRAGYRQ
FDTNDDYYYQVQRPTTGLFTGNRPNAYQHAKFYDLNLSYDFDDRNRLRLDGYLRGSTRGIAPFSIFDPARPFLDSATGEP
QFEITRLVTQANGLALTYDSDLGQARDSKLQVLAAVDRNLVEEFSGVDLGDPGTYTDISVLNFQVRHNWQFNPTNNITYG
FEYQRQFGRSGENSGEITSFDTGQDLPALFALYTWKPLEPLVITAGVRATFVGNIVARGLVRDIPSSVDPSVGFRYQLLP
GLALRGNYQRIYRAPNFNDLFGRTTHIGNPFLEPESGNAFDIGLDWQTGGTSLLRLTYFTADVNNLTDYLLVRNACDLNG
NAPDCNDDPRSNAERFRVNYPRVNSSGLEAAFNWKIASEWSTFATTTLVDSRLVAAPDPATVNNQLVQLGSINNSEDGTF
RVDVAERNALVQTQYPLVPFLTSRLGVTYEPPGGLRASLFANISGGRSVDVNHVGPFDTLHPARLTPGSLLPGYTTVDMS
VRVPLTPSVALNGYVFNLFNSYYERSYGNPGPGINFRVGLSSTF

Specific function: Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TonB-dependent receptor family. BtuB (TC 1.B.14.3.1) subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788478, Length=148, Percent_Identity=31.7567567567568, Blast_Score=69, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010101
- InterPro:   IPR010917 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 83658; Mature: 83658

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.3 %Met     (Translated Protein)
0.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFQVWVLGLGLVLGNPPVHAEHVPTKNELQRQEAGIRTLAQALEPPAVSVSQAPPDETA
CEEEEEEEEEEHEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHH
IESIGPAGSYSLDEVTVTGTLRPARTNETSTTVYTVDRKEIEDKGANSVGEAIRGVPGVQ
HHHCCCCCCCCCCEEEEEEEECCCCCCCCCEEEEEEEHHHHHHCCCCHHHHHHHCCCCCC
SNVFGAGADVHNNFFIRGLPNLGIGILVDGRLITNLNQEHFDLSDLPVYNTERIEVLTGS
CCCEECCCCCCCCEEEEECCCCCEEEEECCEEEECCCCCCCCCCCCCCCCCCEEEEEECC
GTTLYGTNAAGGVINVITRKPTGPLEADLKVEFGGYGYSNYSASYGGKVDKFGFRAGYRQ
CCEEEECCCCCCEEEEEECCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCHHHCCCCC
FDTNDDYYYQVQRPTTGLFTGNRPNAYQHAKFYDLNLSYDFDDRNRLRLDGYLRGSTRGI
CCCCCCEEEEEECCCCEEEECCCCCCCCCCEEEEEEEEECCCCCCEEEEEEEEECCCCCC
APFSIFDPARPFLDSATGEPQFEITRLVTQANGLALTYDSDLGQARDSKLQVLAAVDRNL
CCEECCCCCCHHHHCCCCCCCEEEEEEEHHCCCEEEEECCCCCCCCCCCEEEHHHHHHHH
VEEFSGVDLGDPGTYTDISVLNFQVRHNWQFNPTNNITYGFEYQRQFGRSGENSGEITSF
HHHHCCCCCCCCCCCCEEEEEEEEEEECEEECCCCCEEECCHHHHHHCCCCCCCCCEEEE
DTGQDLPALFALYTWKPLEPLVITAGVRATFVGNIVARGLVRDIPSSVDPSVGFRYQLLP
CCCCCCHHHHHEECCCCCCCEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECC
GLALRGNYQRIYRAPNFNDLFGRTTHIGNPFLEPESGNAFDIGLDWQTGGTSLLRLTYFT
CEEECCCCCEEEECCCCHHHCCCEEECCCCCCCCCCCCEEEEEEECCCCCCEEEEEEEEE
ADVNNLTDYLLVRNACDLNGNAPDCNDDPRSNAERFRVNYPRVNSSGLEAAFNWKIASEW
CCHHHHHHHHHEECCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCEEEEEEEECCC
STFATTTLVDSRLVAAPDPATVNNQLVQLGSINNSEDGTFRVDVAERNALVQTQYPLVPF
CHHEEEEECCCEEEECCCCCCCCCEEEEECCCCCCCCCEEEEEECCCCCEEEECCCHHHH
LTSRLGVTYEPPGGLRASLFANISGGRSVDVNHVGPFDTLHPARLTPGSLLPGYTTVDMS
HHHHCCEEECCCCCCEEEEEEECCCCCEEECCCCCCCCCCCCCCCCCCCCCCCEEEEEEE
VRVPLTPSVALNGYVFNLFNSYYERSYGNPGPGINFRVGLSSTF
EEECCCCCEEECCCHHHHHHHHHHHCCCCCCCCCEEEEECCCCC
>Mature Secondary Structure
MRFQVWVLGLGLVLGNPPVHAEHVPTKNELQRQEAGIRTLAQALEPPAVSVSQAPPDETA
CEEEEEEEEEEHEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHH
IESIGPAGSYSLDEVTVTGTLRPARTNETSTTVYTVDRKEIEDKGANSVGEAIRGVPGVQ
HHHCCCCCCCCCCEEEEEEEECCCCCCCCCEEEEEEEHHHHHHCCCCHHHHHHHCCCCCC
SNVFGAGADVHNNFFIRGLPNLGIGILVDGRLITNLNQEHFDLSDLPVYNTERIEVLTGS
CCCEECCCCCCCCEEEEECCCCCEEEEECCEEEECCCCCCCCCCCCCCCCCCEEEEEECC
GTTLYGTNAAGGVINVITRKPTGPLEADLKVEFGGYGYSNYSASYGGKVDKFGFRAGYRQ
CCEEEECCCCCCEEEEEECCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCHHHCCCCC
FDTNDDYYYQVQRPTTGLFTGNRPNAYQHAKFYDLNLSYDFDDRNRLRLDGYLRGSTRGI
CCCCCCEEEEEECCCCEEEECCCCCCCCCCEEEEEEEEECCCCCCEEEEEEEEECCCCCC
APFSIFDPARPFLDSATGEPQFEITRLVTQANGLALTYDSDLGQARDSKLQVLAAVDRNL
CCEECCCCCCHHHHCCCCCCCEEEEEEEHHCCCEEEEECCCCCCCCCCCEEEHHHHHHHH
VEEFSGVDLGDPGTYTDISVLNFQVRHNWQFNPTNNITYGFEYQRQFGRSGENSGEITSF
HHHHCCCCCCCCCCCCEEEEEEEEEEECEEECCCCCEEECCHHHHHHCCCCCCCCCEEEE
DTGQDLPALFALYTWKPLEPLVITAGVRATFVGNIVARGLVRDIPSSVDPSVGFRYQLLP
CCCCCCHHHHHEECCCCCCCEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECC
GLALRGNYQRIYRAPNFNDLFGRTTHIGNPFLEPESGNAFDIGLDWQTGGTSLLRLTYFT
CEEECCCCCEEEECCCCHHHCCCEEECCCCCCCCCCCCEEEEEEECCCCCCEEEEEEEEE
ADVNNLTDYLLVRNACDLNGNAPDCNDDPRSNAERFRVNYPRVNSSGLEAAFNWKIASEW
CCHHHHHHHHHEECCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCEEEEEEEECCC
STFATTTLVDSRLVAAPDPATVNNQLVQLGSINNSEDGTFRVDVAERNALVQTQYPLVPF
CHHEEEEECCCEEEECCCCCCCCCEEEEECCCCCCCCCEEEEEECCCCCEEEECCCHHHH
LTSRLGVTYEPPGGLRASLFANISGGRSVDVNHVGPFDTLHPARLTPGSLLPGYTTVDMS
HHHHCCEEECCCCCCEEEEEEECCCCCEEECCCCCCCCCCCCCCCCCCCCCCCEEEEEEE
VRVPLTPSVALNGYVFNLFNSYYERSYGNPGPGINFRVGLSSTF
EEECCCCCEEECCCHHHHHHHHHHHCCCCCCCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA