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The map label for this gene is mdtA [H]

Identifier: 37520444

GI number: 37520444

Start: 923319

End: 924500

Strand: Reverse

Name: mdtA [H]

Synonym: gll0875

Alternate gene names: 37520444

Gene position: 924500-923319 (Counterclockwise)

Preceding gene: 37520445

Following gene: 37520442

Centisome position: 19.84

GC content: 66.5

Gene sequence:

>1182_bases
ATGCCTTCTTCGACAACGTCAAAGGTGATAGCCGGCCTCGTCGTAGGCGGTTTGCTATTCGGGGGACTGTTCGCCCTGGG
TTTGCTTCCCCGCCTCACTCGTCAGCAGGAGTTGCTTGCCGCGGCAAACGAAGCGGCGAGCGAAACCAGTGTTGTGGCGT
TGGCGCGCCCGACGCGCGCGGCGGCCCCGGCTCCTGTGCGGCTACCCGGCAACATCCAGGCTTTGCAGGAAACGGTCGTG
AACGCCCGCTCAGACGGTTACCTGCGCCGCCGCCTCGTCGATATCGGCGACCGGGTGCGCTCGGGCCAACTGCTGGCCGA
GATCGACACCCCCGAACTAGATCAACGGGTGAGCGAACTGCGCTCGACATTGGCCCAGGCCCGCGCCGATCTCCAGCAAC
AGGAGGCCAATTTGGCCCTCGCCCGCACCACCTTCGAGCGCTGGCGCACTCTGCGCGAGGAGCGAGCCGTCTCCCAGCAG
GACGTCGATGAGCGCCAATCGGCCTACCGGGCGCAAATGGCGGCGGTCGAAGCCCAGCGCGCCAACCTCCGCGCCCGCCA
GGCGGATCTCGATCGGCAGGTGGCCTTGCAAAACTTCAAGCAGGTGCGCGCCCCTTTTTCGGGTATCGTCACCGCCCGCA
ACGTCGATACCGGGGCGCTCATCGCCGCAGGCAGCAGCCAGAACGGTCTATTTCGGGTCGCCAAAACTGAGCGATTGCGC
ATCTTCATCGATGTGCCCCAGACTTTTGCTCCAGCAATCCGAGCCGGCCAGAGCGCCCGAGTCTCTGTCCAGGAGTACCC
GCGCCCCTTCGAAGGCCGGGTGACGCGCACGGCGGGTGCGCTCGACCCGGCGGCGCGCACGCTGCGCACTGAGGTGCAGC
TCGACAACCGCAACGACCGGCTGCTGCCGGGTATGTACGCCCAGGTGGAGATCGCGGGTAGGCGAGTCAGCCCACCGCTC
ACCGTCCCGGCCAATACGCTGCTGGTGCGCGCGGGGAGCACGCAGGTGGCGGTGGTGGGTTCCGACAGCGTCGTACACTT
GCGCCGGGTAGGTCTCGGGCGCGATCTGGGCGAAACGGTAGAAATTGTCTCGGGACTTGTCGGCAGCGAACGGCTGGTGG
TCAATCCGGGCGACGAGATTGCCGAGGGCAAGAAAGTCGAAGTTGCGGCTCCGCACGAGTAG

Upstream 100 bases:

>100_bases
GCCGCCCCACGATCCGGAGGCCGAGGAAACTGAACCCGCCGAATCCCTTGCCCGCCCCGCCTACTCAGCCCTACCGCAGC
AACAGCAGGAGTAGTCCGCC

Downstream 100 bases:

>100_bases
CCGCGAGCGTGGGCACAAAGCTTCCAGGCCACGGGTGTTAAAACGCTTAACTTGCCACCGACTTGGCAGGCCGCTCCGGA
CGGGGAGGCTTGCCTTTGGC

Product: HlyD family multidrug efflux protein

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 393; Mature: 392

Protein sequence:

>393_residues
MPSSTTSKVIAGLVVGGLLFGGLFALGLLPRLTRQQELLAAANEAASETSVVALARPTRAAAPAPVRLPGNIQALQETVV
NARSDGYLRRRLVDIGDRVRSGQLLAEIDTPELDQRVSELRSTLAQARADLQQQEANLALARTTFERWRTLREERAVSQQ
DVDERQSAYRAQMAAVEAQRANLRARQADLDRQVALQNFKQVRAPFSGIVTARNVDTGALIAAGSSQNGLFRVAKTERLR
IFIDVPQTFAPAIRAGQSARVSVQEYPRPFEGRVTRTAGALDPAARTLRTEVQLDNRNDRLLPGMYAQVEIAGRRVSPPL
TVPANTLLVRAGSTQVAVVGSDSVVHLRRVGLGRDLGETVEIVSGLVGSERLVVNPGDEIAEGKKVEVAAPHE

Sequences:

>Translated_393_residues
MPSSTTSKVIAGLVVGGLLFGGLFALGLLPRLTRQQELLAAANEAASETSVVALARPTRAAAPAPVRLPGNIQALQETVV
NARSDGYLRRRLVDIGDRVRSGQLLAEIDTPELDQRVSELRSTLAQARADLQQQEANLALARTTFERWRTLREERAVSQQ
DVDERQSAYRAQMAAVEAQRANLRARQADLDRQVALQNFKQVRAPFSGIVTARNVDTGALIAAGSSQNGLFRVAKTERLR
IFIDVPQTFAPAIRAGQSARVSVQEYPRPFEGRVTRTAGALDPAARTLRTEVQLDNRNDRLLPGMYAQVEIAGRRVSPPL
TVPANTLLVRAGSTQVAVVGSDSVVHLRRVGLGRDLGETVEIVSGLVGSERLVVNPGDEIAEGKKVEVAAPHE
>Mature_392_residues
PSSTTSKVIAGLVVGGLLFGGLFALGLLPRLTRQQELLAAANEAASETSVVALARPTRAAAPAPVRLPGNIQALQETVVN
ARSDGYLRRRLVDIGDRVRSGQLLAEIDTPELDQRVSELRSTLAQARADLQQQEANLALARTTFERWRTLREERAVSQQD
VDERQSAYRAQMAAVEAQRANLRARQADLDRQVALQNFKQVRAPFSGIVTARNVDTGALIAAGSSQNGLFRVAKTERLRI
FIDVPQTFAPAIRAGQSARVSVQEYPRPFEGRVTRTAGALDPAARTLRTEVQLDNRNDRLLPGMYAQVEIAGRRVSPPLT
VPANTLLVRAGSTQVAVVGSDSVVHLRRVGLGRDLGETVEIVSGLVGSERLVVNPGDEIAEGKKVEVAAPHE

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87081796, Length=320, Percent_Identity=28.75, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI87082036, Length=326, Percent_Identity=25.7668711656442, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI1789929, Length=305, Percent_Identity=24.9180327868852, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 42486; Mature: 42355

Theoretical pI: Translated: 10.84; Mature: 10.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSSTTSKVIAGLVVGGLLFGGLFALGLLPRLTRQQELLAAANEAASETSVVALARPTRA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCC
AAPAPVRLPGNIQALQETVVNARSDGYLRRRLVDIGDRVRSGQLLAEIDTPELDQRVSEL
CCCCCEECCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHH
RSTLAQARADLQQQEANLALARTTFERWRTLREERAVSQQDVDERQSAYRAQMAAVEAQR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
ANLRARQADLDRQVALQNFKQVRAPFSGIVTARNVDTGALIAAGSSQNGLFRVAKTERLR
HHHHHHHHHHHHHHHHHHHHHHHCCHHHCEEECCCCCCEEEEECCCCCCEEEEEECCEEE
IFIDVPQTFAPAIRAGQSARVSVQEYPRPFEGRVTRTAGALDPAARTLRTEVQLDNRNDR
EEEECCHHHHHHHHCCCCCEEEHHHCCCCCCCCEEECCCCCCHHHHHHHHHEEECCCCCC
LLPGMYAQVEIAGRRVSPPLTVPANTLLVRAGSTQVAVVGSDSVVHLRRVGLGRDLGETV
CCCCCEEEEEECCCCCCCCCCCCCCEEEEECCCCEEEEECCCCEEEHHHHCCCCCHHHHH
EIVSGLVGSERLVVNPGDEIAEGKKVEVAAPHE
HHHHHHCCCCEEEECCCHHHCCCCEEEEECCCC
>Mature Secondary Structure 
PSSTTSKVIAGLVVGGLLFGGLFALGLLPRLTRQQELLAAANEAASETSVVALARPTRA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCC
AAPAPVRLPGNIQALQETVVNARSDGYLRRRLVDIGDRVRSGQLLAEIDTPELDQRVSEL
CCCCCEECCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHH
RSTLAQARADLQQQEANLALARTTFERWRTLREERAVSQQDVDERQSAYRAQMAAVEAQR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
ANLRARQADLDRQVALQNFKQVRAPFSGIVTARNVDTGALIAAGSSQNGLFRVAKTERLR
HHHHHHHHHHHHHHHHHHHHHHHCCHHHCEEECCCCCCEEEEECCCCCCEEEEEECCEEE
IFIDVPQTFAPAIRAGQSARVSVQEYPRPFEGRVTRTAGALDPAARTLRTEVQLDNRNDR
EEEECCHHHHHHHHCCCCCEEEHHHCCCCCCCCEEECCCCCCHHHHHHHHHEEECCCCCC
LLPGMYAQVEIAGRRVSPPLTVPANTLLVRAGSTQVAVVGSDSVVHLRRVGLGRDLGETV
CCCCCEEEEEECCCCCCCCCCCCCCEEEEECCCCEEEEECCCCEEEHHHHCCCCCHHHHH
EIVSGLVGSERLVVNPGDEIAEGKKVEVAAPHE
HHHHHHCCCCEEEECCCHHHCCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA